Cited by 160Genetic Associations and EpidemiologyIntergenerational and Educational Inequality StudiesCognitive Abilities and Testing

Genetic link between family socioeconomic status and children’s educational achievement estimated from genome-wide SNPs

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Krapohl, E, Plomin, R·2016·Molecular Psychiatry

Abstract

One of the best predictors of children's educational achievement is their family's socioeconomic status (SES), but the degree to which this association is genetically mediated remains unclear. For 3000 UK-representative unrelated children we found that genome-wide single-nucleotide polymorphisms could explain a third of the variance of scores on an age-16 UK national examination of educational achievement and half of the correlation between their scores and family SES. Moreover, genome-wide polygenic scores based on a previously published genome-wide association meta-analysis of total number of years in education accounted for ~3.0% variance in educational achievement and ~2.5% in family SES. This study provides the first molecular evidence for substantial genetic influence on differences in children's educational achievement and its association with family SES.

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  1. OECD Education at a Glance 2013. Organisation for Economic Co-operation and Development, 2013 Available at http://www.oecd-ilibrary.org/content/book/eag_highlights-2013-en.
  2. Saunders P. Social Mobility Delusions: Why So Much of What Politicians Say about Social Mobility in Britain Is Wrong, Misleading or Unreliable. Civitas: London, UK, 2012.

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Authors
Krapohl, E., & Plomin, R.
Affiliations
King's College London (GB)
Corresponding author
Krapohl, E
Venue
Molecular Psychiatry
Published
2015-03-10
Volume
21
Issue
3
Pages
437-443
ISSN
  • 1359-4184 (ISSN-L)
  • 1476-5578
OpenAlex
W2044538991
Cited by
160
References
64
Citations by year
2026: 4 · 2025: 6 · 2024: 11 · 2023: 8 · 2022: 16 · 2021: 12 · 2020: 21 · 2019: 31 · 2018: 15 · 2017: 16 · 2016: 14 · 2015: 5 · 2012: 1
FWCI
11.39
Type
journal article
Language
en
Open access
Locations
  • Molecular Psychiatry (publishedVersion, cc-by)
  • Research Portal (King's College London) (publishedVersion, cc-by)
  • PubMed Central (publishedVersion, cc-by)
  • PubMed (publishedVersion)
Funders
  • National Institutes of Health (G0901245)
  • Medical Research Council (G0901245, G19/2, previously G0500079, G0500079, 295366)
  • Eunice Kennedy Shriver National Institute of Child Health and Human Development (HD044454, R01HD059215, HD059215, R01HD044454)
Topics
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Genetic Associations and Epidemiology
  • Social Sciences › Sociology and Political Science › Intergenerational and Educational Inequality Studies
  • Social Sciences › Psychology › Experimental and Cognitive Psychology › Cognitive Abilities and Testing
Keywords
academic performance, family socioeconomic status, genetic mediation, polygenic risk score, single nucleotide polymorphisms, years of schooling, children
MeSH terms
Adolescent, Child, Child, Preschool, Educational Status, Family, Female, Genotype, United Kingdom, Humans, Intelligence, Male, Social Class, Oligonucleotide Array Sequence Analysis, Multifactorial Inheritance, Polymorphism, Single Nucleotide, Genome-Wide Association Study

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