The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
The exocyst complex is required for targeting of Glut4 to the plasma membrane by insulin
Open accessOverview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Insulin signalling and the regulation of glucose and lipid metabolism
Saltiel, A. R., & Kahn, C. R. (2001) · Nature · doi:10.1038/414799a · Cited by 5,326
Self-citation
Cited by
Mechanisms of Insulin Action and Insulin Resistance
Petersen, M. C., & Shulman, G. I. (2018) · Physiological Reviews · doi:10.1152/physrev.00063.2017 · Cited by 3,028
The Dynamics of Genome-wide DNA Methylation Reprogramming in Mouse Primordial Germ Cells
Seisenberger, S., Andrews, S., Krueger, F., Arand, J., Walter, J., Santos, F., Popp, C., Thienpont, B., Dean, W., & Reik, W. (2012) · Molecular Cell · doi:10.1016/j.molcel.2012.11.001 · Cited by 973
Regulation of glucose transport by insulin: traffic control of GLUT4
Leto, D., & Saltiel, A. R. (2012) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm3351 · Cited by 848
Self-citationMîinea, C. P., Sano, H., Kane, S., Sano, E., Fukuda, M., Peränen, J., Lane, W. S., & Lienhard, G. E. (2005) · Biochemical Journal · doi:10.1042/bj20050887 · Cited by 449
Insulin signaling in health and disease
Saltiel, A. R. (2021) · Journal of Clinical Investigation · doi:10.1172/jci142241 · Cited by 446
Self-citationThe exocyst complex in polarized exocytosis
He, B., & Guo, W. (2009) · Current Opinion in Cell Biology · doi:10.1016/j.ceb.2009.04.007 · Cited by 438
The exocyst defrocked, a framework of rods revealed
Munson, M., & Novick, P. (2006) · Nature Structural & Molecular Biology · doi:10.1038/nsmb1097 · Cited by 290
Regulation of Glucose Transporter Translocation in Health and Diabetes
Bogan, J. S. (2012) · Annual Review of Biochemistry · doi:10.1146/annurev-biochem-060109-094246 · Cited by 279
Ishiki, M., & Klip, A. (2005) · Endocrinology · doi:10.1210/en.2005-0850 · Cited by 281
Wu, B., & Guo, W. (2015) · Journal of Cell Science · doi:10.1242/jcs.156398 · Cited by 240
Ral GTPases Regulate Exocyst Assembly through Dual Subunit Interactions
Moskalenko, S., Tong, C., Rosse, C., Mirey, G., Formstecher, E., Daviet, L., Camonis, J., & White, M. A. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m308702200 · Cited by 238
Chapter 21 Interleukin‐6 and Insulin Resistance
Kim, J., Bachmann, R. A., & Chen, J. (2009) · Vitamins & Hormones · doi:10.1016/s0083-6729(08)00621-3 · Cited by 224
Multiple roles for the actin cytoskeleton during regulated exocytosis
Porat-Shliom, N., Milberg, O., Masedunskas, A., & Weigert, R. (2013) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-012-1156-5 · Cited by 181
Xia, W., Veeragandham, P., Cao, Y., Xu, Y., Rhyne, T. E., Qian, J., Hung, C.-W., Zhao, P., Jones, Y., Gao, H., et al. (2024) · Nature Metabolism · doi:10.1038/s42255-024-00978-0 · Cited by 176
Self-citationDual role of the exocyst in AMPA receptor targeting and insertion into the postsynaptic membrane
Gerges, N. Z., Backos, D. S., Rupasinghe, C. N., Spaller, M. R., & Esteban, J. A. (2006) · The EMBO Journal · doi:10.1038/sj.emboj.7601065 · Cited by 147
Exo84 and Sec5 are competitive regulatory Sec6/8 effectors to the RalA GTPase
Jin, R., Junutula, J. R., Matern, H. T., Ervin, K. E., Scheller, R. H., & Brunger, A. T. (2005) · The EMBO Journal · doi:10.1038/sj.emboj.7600699 · Cited by 145
On being the right size: scaling effects in designing a human-on-a-chip
Moraes, C., Labuz, J. M., Leung, B. M., Inoue, M., Chun, T.-H., & Takayama, S. (2013) · Integrative Biology · doi:10.1039/c3ib40040a · Cited by 134
Self-citationMehta, S. Q., Hiesinger, P. R., Beronja, S., Zhai, R. G., Schulze, K. L., Verstreken, P., Cao, Y., Zhou, Y., Tepass, U., Crair, M. C., et al. (2005) · Neuron · doi:10.1016/j.neuron.2005.02.029 · Cited by 136
Structural basis of the interaction between RalA and Sec5, a subunit of the sec6/8 complex
Fukai, S., Matern, H. T., Jagath, J. R., Scheller, R. H., & Brunger, A. T. (2003) · The EMBO Journal · doi:10.1093/emboj/cdg329 · Cited by 126
PI(4,5)P2-binding effector proteins for vesicle exocytosis
Martin, T. F. J. (2015) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · doi:10.1016/j.bbalip.2014.09.017 · Cited by 124
Essential function of Drosophila Sec6 in apical exocytosis of epithelial photoreceptor cells
Beronja, S., Laprise, P., Papoulas, O., Pellikka, M., Sisson, J., & Tepass, U. (2005) · The Journal of Cell Biology · doi:10.1083/jcb.200410081 · Cited by 120
Dupraz, S., Grassi, D., Bernis, M. E., Sosa, L., Bisbal, M., Gastaldi, L., Jausoro, I., Cáceres, A., Pfenninger, K. H., & Quiroga, S. (2009) · The Journal of Neuroscience · doi:10.1523/jneurosci.3907-09.2009 · Cited by 111
A Ral GAP complex links PI 3-kinase/Akt signaling to RalA activation in insulin action
Chen, X.-W., Leto, D., Xiong, T., Yu, G., Cheng, A., Decker, S., & Saltiel, A. R. (2011) · Molecular Biology of the Cell · doi:10.1091/mbc.e10-08-0665 · Cited by 108
Self-citationThrombospondin 1 Mediates High-Fat Diet-Induced Muscle Fibrosis and Insulin Resistance in Male Mice
Inoue, M., Jiang, Y., Barnes, R. H., Tokunaga, M., Martinez-Santibañez, G., Geletka, L., Lumeng, C. N., Buchner, D. A., & Chun, T.-H. (2013) · Endocrinology · doi:10.1210/en.2013-1587 · Cited by 85
Self-citationRab10 associates with primary cilia and the exocyst complex in renal epithelial cells
Babbey, C. M., Bacallao, R. L., & Dunn, K. W. (2010) · American Journal of Physiology-Renal Physiology · doi:10.1152/ajprenal.00198.2010 · Cited by 81
RalA Functions as an Indispensable Signal Mediator for the Nutrient-sensing System
Maehama, T., Tanaka, M., Nishina, H., Murakami, M., Kanaho, Y., & Hanada, K. (2008) · Journal of Biological Chemistry · doi:10.1074/jbc.m805822200 · Cited by 80
Exocyst function regulated by effector phosphorylation
Chen, X.-W., Leto, D., Xiao, J., Goss, J., Wang, Q., Shavit, J. A., Xiong, T., Yu, G., Ginsburg, D., Toomre, D., et al. (2011) · Nature Cell Biology · doi:10.1038/ncb2226 · Cited by 76
Self-citationRoy, D., & Tedeschi, A. (2021) · Cells · doi:10.3390/cells10051078 · Cited by 68
Richter, E. A., Bilan, P. J., & Klip, A. (2025) · Physiological Reviews · doi:10.1152/physrev.00033.2024 · Cited by 64
Insulin regulates leptin secretion from 3T3–L1 adipocytes by a PI 3 kinase independent mechanism
Zeigerer, A., Rodeheffer, M. S., McGraw, T. E., & Friedman, J. M. (2008) · Experimental Cell Research · doi:10.1016/j.yexcr.2008.04.003 · Cited by 46
Regulation of Platelet Dense Granule Secretion by the Ral GTPase-Exocyst Pathway
Kawato, M., Shirakawa, R., Kondo, H., Higashi, T., Ikeda, T., Okawa, K., Fukai, S., Nureki, O., Kita, T., & Horiuchi, H. (2008) · Journal of Biological Chemistry · doi:10.1074/jbc.m705340200 · Cited by 46
Papadopoulos, T., Rhee, H. J., Subramanian, D., Paraskevopoulou, F., Mueller, R., Schultz, C., Brose, N., Rhee, J.-S., & Betz, H. (2017) · Journal of Biological Chemistry · doi:10.1074/jbc.m116.771592 · Cited by 38
Sano, H., Peck, G. R., Blachon, S., & Lienhard, G. E. (2015) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2015.08.069 · Cited by 35
Metadata
- Authors
- Inoue, M., Chang, L., Hwang, J., Chiang, S.-H., & Saltiel, A. R.
- Venue
- Nature
- Published
- 2003-04
- Volume
- 422
- Issue
- 6932
- Pages
- 629-633
- ISSN
- 0028-0836 (ISSN-L)
- 1476-4687
- OpenAlex
- W2004102471
- Cited by
- 354
- References
- 1
- FWCI
- 9.60
- Type
- journal article
- Language
- en
- Open access
- green
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
