Cell-cycle checkpoints and cancer

The Causes of Cancer: Quantitative Estimates of Avoidable Risks of Cancer in the United States Today

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The Causes of Cancer: Quantitative Estimates of Avoidable Risks of Cancer in the United States Today

Peto, R. (1983) · Springer eBooks · doi:10.1007/978-1-4757-1117-2_30 · Cited by 3,504

DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation

Bakkenist, C. J., & Kastan, M. B. (2003) · Nature · doi:10.1038/nature01368 · Cited by 3,466

Checkpoints: Controls That Ensure the Order of Cell Cycle Events

Hartwell, L. H., & Weinert, T. A. (1989) · Science · doi:10.1126/science.2683079 · Cited by 3,053

Sensing DNA Damage Through ATRIP Recognition of RPA-ssDNA Complexes

Zou, L., & Elledge, S. J. (2003) · Science · doi:10.1126/science.1083430 · Cited by 2,693

ATM and related protein kinases: safeguarding genome integrity

Shiloh, Y. (2003) · Nature Reviews Cancer · doi:10.1038/nrc1011 · Cited by 2,577

Megabase Chromatin Domains Involved in DNA Double-Strand Breaks in Vivo

Rogakou, E. P., Boon, C., Redon, C., & Bonner, W. M. (1999) · The Journal of Cell Biology · doi:10.1083/jcb.146.5.905 · Cited by 2,422

Breast and Ovarian Cancer Risks Due to Inherited Mutations in BRCA1 and BRCA2

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Cell cycle checkpoint signaling through the ATM and ATR kinases

Abraham, R. T. (2001) · Genes & Development · doi:10.1101/gad.914401 · Cited by 1,966

Cancer Susceptibility and the Functions of BRCA1 and BRCA2

Venkitaraman, A. R. (2002) · Cell · doi:10.1016/s0092-8674(02)00615-3 · Cited by 1,713

E2F1 promotes the recruitment of DNA repair factors to sites of DNA double-strand breaks

Chen, J., Zhu, F., Weaks, R. L., Biswas, A., Guo, R. R., Li, Y., & Johnson, D. G. (2011) · Cell Cycle · doi:10.4161/cc.10.8.15341 · Cited by 76

Polo-like kinases mediate cell survival in mitochondrial dysfunction

Matsumoto, T., Wang, P., Ma, W., Sung, H. J., Matoba, S., & Hwang, P. M. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0904229106 · Cited by 75

Maintenance of the DNA-Damage Checkpoint Requires DNA-Damage-Induced Mediator Protein Oligomerization

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A water soluble parthenolide analog suppresses in vivo tumor growth of two tobacco‐associated cancers, lung and bladder cancer, by targeting NF‐κB and generating reactive oxygen species

Shanmugam, R., Kusumanchi, P., Appaiah, H. N., Liang Cheng, C., Crooks, P. A., Neelakantan, S., Peat, T. J., Klaunig, J. E., Matthews, W., Nakshatri, H., et al. (2010) · International Journal of Cancer · doi:10.1002/ijc.25587 · Cited by 75

The DNA Damage Response Induced by Infection with Human Cytomegalovirus and Other Viruses

Xiaofei, E., & Kowalik, T. F. (2014) · Viruses · doi:10.3390/v6052155 · Cited by 80

Aurora B opposes PP1 function in mitosis by phosphorylating the conserved PP1-binding RVxF motif in PP1 regulatory proteins

Nasa, I., Rusin, S. F., Kettenbach, A. N., & Moorhead, G. B. G. (2018) · Science Signaling · doi:10.1126/scisignal.aai8669 · Cited by 75

Cell migration and adhesion of a human melanoma cell line is decreased by cold plasma treatment

Schmidt, A., Bekeschus, S., von Woedtke, T., & Hasse, S. (2015) · Clinical Plasma Medicine · doi:10.1016/j.cpme.2015.05.003 · Cited by 77

PFKFB3 blockade inhibits hepatocellular carcinoma growth by impairing DNA repair through AKT

Shi, W.-K., Zhu, X.-D., Wang, C.-H., Zhang, Y.-Y., Cai, H., Li, X., Cao, M.-Q., Zhang, S.-Z., Li, K.-S., & Sun, H. (2018) · Cell Death and Disease · doi:10.1038/s41419-018-0435-y · Cited by 74

NR4A1 regulates expression of immediate early genes, suppressing replication stress in cancer

Guo, H., Golczer, G., Wittner, B. S., Langenbucher, A., Zachariah, M. A., Dubash, T. D., Hong, X., Comaills, V., Burr, R., Ebright, R. Y., et al. (2021) · Molecular Cell · doi:10.1016/j.molcel.2021.09.016 · Cited by 79

Computational systems biology of the cell cycle

Csikász‐Nagy, A. (2009) · Briefings in Bioinformatics · doi:10.1093/bib/bbp005 · Cited by 76

Safety, Antitumor Activity, and Biomarker Analysis in a Phase I Trial of the Once-daily Wee1 Inhibitor Adavosertib (AZD1775) in Patients with Advanced Solid Tumors

Takebe, N., Naqash, A. R., Coyne, G. O., Kummar, S., Do, K. T., Bruns, A. B., Juwara, L., Zlott, J., Rubinstein, L., Piekarz, R., et al. (2021) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-21-0329 · Cited by 73

cGAS/STING cross-talks with cell cycle and potentiates cancer immunotherapy

Long, Z., Wang, J., Xu, J., Lei, X., & Liu, Q. (2022) · Molecular Therapy · doi:10.1016/j.ymthe.2022.01.044 · Cited by 76

Combined experimental and computational analysis of DNA damage signaling reveals context‐dependent roles for Erk in apoptosis and G1/S arrest after genotoxic stress

Tentner, A. R., Lee, M. J., Ostheimer, G. J., Samson, L. D., Lauffenburger, D. A., & Yaffe, M. B. (2012) · Molecular Systems Biology · doi:10.1038/msb.2012.1 · Cited by 74

Cigarette smoke extract induced cytokine and chemokine gene expression changes in COPD macrophages

Kent, L. M., Smyth, L. J. C., Clayton, C. L., Scott, L., Cook, T., Stephens, R., Fox, S. M., Hext, P., Farrow, S. N., & Singh, D. (2008) · Cytokine · doi:10.1016/j.cyto.2008.02.001 · Cited by 73

Genistein exhibits anti-cancer effects via down-regulating FoxM1 in H446 small-cell lung cancer cells

Tiantian, T., Li, J., Li, B., Wang, Y., Li, M., Ma, D., & Wang, X. (2013) · Tumor Biology · doi:10.1007/s13277-013-1542-0 · Cited by 73

DNA Methylation of Tumor Suppressor Mirna Genes: A Lesson from the miR-34 family

Wong, K. Y., Yu, L., & Chim, C. S. (2011) · Epigenomics · doi:10.2217/epi.10.74 · Cited by 75

Origin licensing and p53 status regulate Cdk2 activity during G1

Nevis, K. R., Cordeiro‐Stone, M., & Cook, J. G. (2009) · Cell Cycle · doi:10.4161/cc.8.12.8811 · Cited by 73

Drosophila melanogaster: a Model for the Study of DNA Damage Checkpoint Response

Song, Y. (2005) · Molecules and Cells · doi:10.1016/s1016-8478(23)13152-9 · Cited by 73

Zika Virus Infection Induces DNA Damage Response in Human Neural Progenitors That Enhances Viral Replication

Hammack, C., Ogden, S. C., Madden, J. C., Medina, A., Xu, C., Phillips, E. O. N., Son, Y., Cone, A. S., Giovinazzi, S., Didier, R., et al. (2019) · Journal of Virology · doi:10.1128/jvi.00638-19 · Cited by 73

Assessment of ATM phosphorylation on Ser‐1981 induced by DNA topoisomerase I and II inhibitors in relation to Ser‐139‐histone H2AX phosphorylation, cell cycle phase, and apoptosis

Kurose, A., Tanaka, T., Huang, X., Halicka, H. D., Traganos, F., Dai, W. H., & Darżynkiewicz, Z. (2005) · Cytometry Part A · doi:10.1002/cyto.a.20186 · Cited by 74

Policing Cancer: Vitamin D Arrests the Cell Cycle

Bhoora, S., & Punchoo, R. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21239296 · Cited by 75

Targeting Wee1 kinase as a therapeutic approach in Hematological Malignancies

Vakili‐Samiani, S., Jalil, A. T., Abdelbasset, W. K., Yumashev, A. V., Karpisheh, V., Jalali, P., Adibfar, S., Ahmadi, M., Feizi, A. A. H., & Jadidi‐Niaragh, F. (2021) · DNA repair · doi:10.1016/j.dnarep.2021.103203 · Cited by 74

Autophagy induction by leptin contributes to suppression of apoptosis in cancer cells and xenograft model: Involvement of p53/FoxO3A axis

Nepal, S., Kim, M. J., Hong, J. T., Kim, S. H., Sohn, D., Lee, S. H., Song, K., Choi, D. Y., Lee, E. S., & Park, P. (2015) · Oncotarget · doi:10.18632/oncotarget.3347 · Cited by 74

Enhancement of radiation response by inhibition of Aurora-A kinase using siRNA or a selective Aurora kinase inhibitor PHA680632 in p53-deficient cancer cells

Tao, Y., Zhang, P., Frascogna, V., Lécluse, Y., Auperin, A., Bourhis, J., & Deutsch, É. (2007) · British Journal of Cancer · doi:10.1038/sj.bjc.6604083 · Cited by 72

Replicative stress, stem cells and aging

Ruzankina, Y., Asare, A., & Brown, E. J. (2008) · Mechanisms of Ageing and Development · doi:10.1016/j.mad.2008.03.009 · Cited by 73

Discovery of pyrazolo[1,5-a]pyrimidine-based CHK1 inhibitors: A template-based approach—Part 1

Dwyer, M. P., Paruch, K., Labroli, M. A., Alvarez, C., Keertikar, K. M., Poker, C., Rossman, R. R., Fischmann, T. O., Duca, J. S., Madison, V., et al. (2010) · Bioorganic & Medicinal Chemistry Letters · doi:10.1016/j.bmcl.2010.10.113 · Cited by 72

Mutations in Proline 82 of p53 Impair Its Activation by Pin1 and Chk2 in Response to DNA Damage

Berger, M., Stahl, N., Sal, G. D., & Haupt, Y. (2005) · Molecular and Cellular Biology · doi:10.1128/mcb.25.13.5380-5388.2005 · Cited by 72

USP39 regulates DNA damage response and chemo-radiation resistance by deubiquitinating and stabilizing CHK2

Wu, J., Chen, Y., Geng, G., Li, L., Yin, P., Nowsheen, S., Li, Y., Wu, C., Liu, J., Zhao, F., et al. (2019) · Cancer Letters · doi:10.1016/j.canlet.2019.02.015 · Cited by 71

The bromodomain containing protein BRD-9 orchestrates RAD51–RAD54 complex formation and regulates homologous recombination-mediated repair

Zhou, Q., Huang, J., Zhang, C., Zhao, F., Kim, W., Tu, X., Zhang, Y., Nowsheen, S., Zhu, Q., Deng, M., et al. (2020) · Nature Communications · doi:10.1038/s41467-020-16443-x · Cited by 71

Influence of cell cycle on responses of MCF-7 cells to benzo[a]pyrene

Hamouchene, H., Arlt, V. M., Giddings, I., & Phillips, D. H. (2011) · BMC Genomics · doi:10.1186/1471-2164-12-333 · Cited by 71

A Conserved DNA Damage Response Pathway Responsible for Coupling the Cell Division Cycle to the Circadian and Metabolic Cycles

Chen, Z., & McKnight, S. L. (2007) · Cell Cycle · doi:10.4161/cc.6.23.5041 · Cited by 72

Increased Tumorigenicity and Sensitivity to Ionizing Radiation upon Loss of Chromosomal Protein HMGN1

Birger, Y., Catez, F., Furusawa, T., Lim, J. H., Prymakowska-Bosak, M., West, K. L., Postnikov, Y. V., Haines, D. C., & Bustin, M. (2005) · Cancer Research · doi:10.1158/0008-5472.can-05-0310 · Cited by 73

NG2 expression in glioblastoma identifies an actively proliferating population with an aggressive molecular signature

Al-Mayhani, M. T. F., Grenfell, R. D., Narita, M., Piccirillo, S. G. M., Kenney-Herbert, E., Fawcett, J. W., Collins, V. P., Ichimura, K., & Watts, C. (2011) · Neuro-Oncology · doi:10.1093/neuonc/nor088 · Cited by 74

Knock-down of hypoxia-induced carbonic anhydrases IX and XII radiosensitizes tumor cells by increasing intracellular acidosis

Doyen, J., Parks, S. K., Marcié, S., Pouysségur, J., & Chiche, J. (2013) · Frontiers in Oncology · doi:10.3389/fonc.2012.00199 · Cited by 71

Genotoxic Stress-Induced Cyclin D1 Phosphorylation and Proteolysis Are Required for Genomic Stability

Pontano, L. L., Aggarwal, P., Barbash, O., Brown, E. J., Bassing, C. H., & Diehl, J. A. (2008) · Molecular and Cellular Biology · doi:10.1128/mcb.01085-08 · Cited by 77

Differences in MWCNT- and SWCNT-induced DNA methylation alterations in association with the nuclear deposition

Öner, D., Ghosh, M., Bové, H., Moisse, M., Boeckx, B., Duca, R. C., Poels, K. L. C., Luyts, K., Putzeys, E., LANDUYT, K. L. V., et al. (2018) · Particle and Fibre Toxicology · doi:10.1186/s12989-018-0244-6 · Cited by 71

Bifunctional Mononuclear Dysprosium Complexes: Single-Ion Magnet Behaviors and Antitumor Activities

Zou, H., Meng, T., Chen, Q. H., Zhang, Y., Wang, H., Li, B., Wang, K., Chen, Z., & Liang, F. (2019) · Inorganic Chemistry · doi:10.1021/acs.inorgchem.8b02250 · Cited by 71

Checkpoint adaptation in human cells

Syljuåsen, R. G. (2007) · Oncogene · doi:10.1038/sj.onc.1210402 · Cited by 78

Recruitment of DNA damage checkpoint proteins to damage in transcribed and nontranscribed sequences

Jiang, G., & Sancar, A. (2006) · Molecular and Cellular Biology · doi:10.1128/mcb.26.1.39-49.2006 · Cited by 70

High in vivo antitumor activity of cobalt oxoisoaporphine complexes by targeting G-quadruplex DNA, telomerase and disrupting mitochondrial functions

Qin, Q., Qin, J.-L., Meng, T., Lin, W., Zhang, C., Wei, Z., Chen, J.-N., Liu, Y., Liang, H., & Chen, Z. (2016) · European Journal of Medicinal Chemistry · doi:10.1016/j.ejmech.2016.08.063 · Cited by 70

Long Non-Coding RNA LUCAT1 Promotes Proliferation and Invasion in Clear Cell Renal Cell Carcinoma Through AKT/GSK-3β Signaling Pathway

Zheng, Z., Zhao, F., Zhu, D., Han, J., Chen, H., Cai, Y., Chen, Z., & Xie, W. (2018) · Cellular Physiology and Biochemistry · doi:10.1159/000491957 · Cited by 70

SKA3 Promotes tumor growth by regulating CDK2/P53 phosphorylation in hepatocellular carcinoma

Hou, Y., Wang, Z., Huang, S., Sun, C., Zhao, J., Shi, J., Li, Z., Wang, Z., He, X., Tam, N. L., et al. (2019) · Cell Death and Disease · doi:10.1038/s41419-019-2163-3 · Cited by 70

Evaluating putative mechanisms of the mitotic spindle checkpoint

Doncic, A., Ben‐Jacob, E., & Barkai, N. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0409142102 · Cited by 70

Axitinib induces DNA damage response leading to senescence, mitotic catastrophe, and increased NK cell recognition in human renal carcinoma cells

Morelli, M. B., Amantini, C., Santoni, M., Soriani, A., Nabissi, M., Cardinali, C., Santoni, A., & Santoni, G. (2015) · Oncotarget · doi:10.18632/oncotarget.5768 · Cited by 70

The versatile functions of ATM kinase

Xu, B., & Boohaker, R. J. (2014) · Biomedical Journal · doi:10.4103/2319-4170.125655 · Cited by 71

Ataxia–telangiectasia

Perlman, S., Boder, E., Sedgewick, R. P., & Gatti, R. A. (2011) · Handbook of clinical neurology · doi:10.1016/b978-0-444-51892-7.00019-x · Cited by 70

Molecular Biology of Glioma

Marumoto, T., & Saya, H. (2012) · Advances in experimental medicine and biology · doi:10.1007/978-1-4614-3146-6_1 · Cited by 70

Anti-prostate cancer activity of a β-carboline alkaloid enriched extract from Rauwolfia vomitoria

Bemis, D. L., Capodice, J. L., Gorroochurn, P., Katz, A. E., & Buttyan, R. (2006) · International Journal of Oncology · doi:10.3892/ijo.29.5.1065 · Cited by 70

De Novo VPS4A Mutations Cause Multisystem Disease with Abnormal Neurodevelopment

Rodger, C. E., Flex, E., Allison, R. J., Sanchis‐Juan, A., Hasenahuer, M. A., Cecchetti, S., French, C. E., Edgar, J. R., Carpentieri, G., Ciolfi, A., et al. (2020) · The American Journal of Human Genetics · doi:10.1016/j.ajhg.2020.10.012 · Cited by 69

Cell Signaling Pathways That Promote Radioresistance of Cancer Cells

Ouellette, M. M., Zhou, S., & Yan, Y. (2022) · Diagnostics · doi:10.3390/diagnostics12030656 · Cited by 74

The p53 protein and its molecular network: Modelling a missing link between DNA damage and cell fate

Eliaš, J., Dimitrio, L., Clairambault, J., & Natalini, R. (2013) · Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics · doi:10.1016/j.bbapap.2013.09.019 · Cited by 74

Reactive Oxygen Species Mediate Isoalantolactone-Induced Apoptosis in Human Prostate Cancer Cells

Rasul, A., Di, J., Millimouno, F. M., Malhi, M., Tsuji, I., Ali, M., Li, J., & Li, X. (2013) · Molecules · doi:10.3390/molecules18089382 · Cited by 69

Molecular Targets and Mechanisms of Radiosensitization Using DNA Damage Response Pathways

Raleigh, D. R., & Haas-Kogan, D. A. (2013) · Future Oncology · doi:10.2217/fon.12.185 · Cited by 71

Fourier Transform Infrared Microspectroscopy and Multivariate Methods for Radiobiological Dosimetry

Meade, A. D., Clarke, C., Byrne, H. J., & Lyng, F. M. (2010) · Radiation Research · doi:10.1667/rr1836.1 · Cited by 69

RECQL1 and WRN Proteins Are Potential Therapeutic Targets in Head and Neck Squamous Cell Carcinoma

Arai, A., Chano, T., Futami, K., Furuichi, Y., Ikebuchi, K., Inui, T., Tameno, H., Ochi, Y., Shimada, T., Hisa, Y., et al. (2011) · Cancer Research · doi:10.1158/0008-5472.can-11-0320 · Cited by 70

Two New Faces of Amifostine: Protector from DNA Damage in Normal Cells and Inhibitor of DNA Repair in Cancer Cells

Hofer, M., Falk, M., Komůrková, D., Falková, I., Bačı́ková, A., Klejdus, B., Pagáčová, E., Štefančíková, L., Weiterová, L., Angelis, K. J., et al. (2016) · Journal of Medicinal Chemistry · doi:10.1021/acs.jmedchem.5b01628 · Cited by 69

Small Molecule Fluorescent Probes for G- Quadruplex Visualization as Potential Cancer Theranostic Agents

Chilka, P., Desai, N. N., & Datta, B. (2019) · Molecules · doi:10.3390/molecules24040752 · Cited by 69

Prexasertib, a checkpoint kinase inhibitor: from preclinical data to clinical development

Angius, G., Tomao, S., Stati, V., Vici, P., Bianco, V., & Tomao, F. (2019) · Cancer Chemotherapy and Pharmacology · doi:10.1007/s00280-019-03950-y · Cited by 69

Rad52 depletion in Candida albicans triggers both the DNA‐damage checkpoint and filamentation accompanied by but independent of expression of hypha‐specific genes

Andaluz, E., Ciudad, T., Gómez‐Raja, J., Calderone, R., & Larriba, G. (2006) · Molecular Microbiology · doi:10.1111/j.1365-2958.2005.05038.x · Cited by 69

Exploring the anti‐cancer potential of dietary phytochemicals for the patients with breast cancer: A comprehensive review

Sohel, M., Aktar, S., Biswas, P., Amin, M. A., Hossain, M. A., Ahmed, N., Mim, M. I. H., Islam, F., & Mamun, A. A. (2023) · Cancer Medicine · doi:10.1002/cam4.5984 · Cited by 70

Bridging the gap between in vitro and in vivo: Dose and schedule predictions for the ATR inhibitor AZD6738

Checkley, S., MacCallum, L., Yates, J. W. T., Jasper, P., Luo, H., Tolsma, J., & Bendtsen, C. (2015) · Scientific Reports · doi:10.1038/srep13545 · Cited by 68

New tricks for old drugs: the anticarcinogenic potential of DNA repair inhibitors

Srougi, M. C., Bey, E. A., Dong, Y., Reinicke, K. E., & Boothman, D. A. (2006) · Journal of Molecular Histology · doi:10.1007/s10735-006-9043-8 · Cited by 68

Characterization of Biological Processes through Automated Image Analysis

Rittscher, J. (2010) · Annual Review of Biomedical Engineering · doi:10.1146/annurev-bioeng-070909-105235 · Cited by 70

Protein Phosphatase 2A-Dependent Dephosphorylation of Replication Protein A Is Required for the Repair of DNA Breaks Induced by Replication Stress

Feng, J., Wakeman, T. P., Yong, S. T., Wu, X., Kornbluth, S. A., & Wang, X. (2009) · Molecular and Cellular Biology · doi:10.1128/mcb.00191-09 · Cited by 70

Aryl-phosphorus-containing flame retardants induce oxidative stress, the p53-dependent DNA damage response and mitochondrial impairment in A549 cells

Yuan, S., Han, Y., Ma, M., Rao, K., Wang, Z., Yang, R., Liu, Y., & Zhou, X. (2019) · Environmental Pollution · doi:10.1016/j.envpol.2019.03.109 · Cited by 69

DNA damage repair: anytime, anywhere?

Essers, J., Vermeulen, W., & Houtsmuller, A. B. (2006) · Current Opinion in Cell Biology · doi:10.1016/j.ceb.2006.03.004 · Cited by 67

Significance of the melanocortin 1 receptor in the DNA damage response of human melanocytes to ultraviolet radiation

Swope, V., Alexander, C., Starner, R., Schwemberger, S., Babcock, G., & Abdel‐Malek, Z. A. (2014) · Pigment Cell & Melanoma Research · doi:10.1111/pcmr.12252 · Cited by 67

Papilomavírus humano e neoplasia cervical

da Rosa, M. I., Medeiros, L. R., Rosa, D. D., Bozzetti, M. C., Silva, F. R., & Silva, B. R. (2009) · Cadernos de Saúde Pública · doi:10.1590/s0102-311x2009000500002 · Cited by 69

Human prostate epithelium lacks Wee1A-mediated DNA damage-induced checkpoint enforcement

af Hällström, T., Jäämaa, S., Mönkkönen, M., Peltonen, K., Andersson, L. C., Medema, R. H., Peehl, D. M., & Laiho, M. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0609299104 · Cited by 68

Human Tim-Tipin complex affects the biochemical properties of the replicative DNA helicase and DNA polymerases

Cho, W., Kang, Y., An, Y.-Y., Tappin, I., Hurwitz, J., & Lee, J.-K. (2013) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1222494110 · Cited by 67

Tumour selective targeting of cell cycle kinases for cancer treatment

Aarts, M., Linardopoulos, S., & Turner, N. C. (2013) · Current Opinion in Pharmacology · doi:10.1016/j.coph.2013.03.012 · Cited by 67

Antimycin A as a mitochondrial electron transport inhibitor prevents the growth of human lung cancer A549 cells

Han (1994) · Oncology Reports · doi:10.3892/or_00000061 · Cited by 67

Centchroman induces G0/G1 arrest and Caspase-dependent Apoptosis involving Mitochondrial Membrane Depolarization in MCF-7 and MDA MB-231 Human Breast Cancer Cells

Nigam, M., Ranjan, V., Srivastava, S., Sharma, R., & Balapure, A. K. (2008) · Life Sciences · doi:10.1016/j.lfs.2007.11.028 · Cited by 67

Induction and processing of complex DNA damage in human breast cancer cells MCF-7 and nonmalignant MCF-10A cells

Francisco, D., Peddi, P., Hair, J. M., Flood, B., Cecil, A. M., Kalogerinis, P. T., Sigounas, G., & Georgakilas, A. G. (2007) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2007.10.045 · Cited by 67

RBM3-Regulated Genes Promote DNA Integrity and Affect Clinical Outcome in Epithelial Ovarian Cancer

Ehlén, Õ., Nodin, B., Rexhepaj, E., Brändstedt, J., Uhlén, M., Alvarado-Kristensson, M., Pontén, F., Brennan, D. J., & Jirström, K. (2011) · Translational Oncology · doi:10.1593/tlo.11106 · Cited by 67

Rsf-1, a Chromatin Remodeling Protein, Induces DNA Damage and Promotes Genomic Instability

Sheu, J. J., Guan, B., Choi, J., Lin, A. W., Lee, C., Hsiao, Y.-T., Wang, T., Tsai, F., & Shih, I. (2010) · Journal of Biological Chemistry · doi:10.1074/jbc.m110.138735 · Cited by 67

Aqueous extract from pecan nut [Carya illinoinensis (Wangenh) C. Koch] shell show activity against breast cancer cell line MCF-7 and Ehrlich ascites tumor in Balb-C mice

Hilbig, J., Policarpi, P. D. B., Grinevicius, V. M. A. S., Mota, N. S. R. S., Toaldo, I. M., Bordignon-Luiz, M. T., Pedrosa, R. C., & Block, J. M. (2017) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2017.08.012 · Cited by 67

Orally Bioavailable and Blood–Brain Barrier-Penetrating ATM Inhibitor (AZ32) Radiosensitizes Intracranial Gliomas in Mice

Karlin, J. D., Allen, J., Ahmad, S. F., Hughes, G. D., Sheridan, V. H., Odedra, R., Farrington, P. M., Cadogan, E. B., Riches, L. C., Garcia-Trinidad, A., et al. (2018) · Molecular Cancer Therapeutics · doi:10.1158/1535-7163.mct-17-0975 · Cited by 70

Re-evaluation of the linear no-threshold (LNT) model using new paradigms and modern molecular studies

Tharmalingam, S., Sreetharan, S., Brooks, A. L., & Boreham, D. R. (2019) · Chemico-Biological Interactions · doi:10.1016/j.cbi.2018.11.013 · Cited by 71

Molecular basis of human ATM kinase inhibition

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Aurora‐A expressing tumour cells are deficient for homology‐directed DNA double strand‐break repair and sensitive to PARP inhibition

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