Cited by 1,216Genomics and Phylogenetic StudiesMicrobial Community Ecology and PhysiologyBacterial Genetics and Biotechnology

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Unusual biology across a group comprising more than 15% of domain Bacteria

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Brown, Christopher T., Hug, Laura A., Thomas, Brian C., Sharon, Itai, Castelle, Cindy J., Singh, Andrea, Wilkins, Michael J., Wrighton, Kelly C., Williams, Kenneth H., Banfield, Jillian F.·2015·Nature

DOI 10.1038/nature14486

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Abstract

A prominent feature of the bacterial domain is a radiation of major lineages that are defined as candidate phyla because they lack isolated representatives. Bacteria from these phyla occur in diverse environments and are thought to mediate carbon and hydrogen cycles. Genomic analyses of a few representatives suggested that metabolic limitations have prevented their cultivation. Here we reconstructed 8 complete and 789 draft genomes from bacteria representing >35 phyla and documented features that consistently distinguish these organisms from other bacteria. We infer that this group, which may comprise >15% of the bacterial domain, has shared evolutionary history, and describe it as the candidate phyla radiation (CPR). All CPR genomes are small and most lack numerous biosynthetic pathways. Owing to divergent 16S ribosomal RNA (rRNA) gene sequences, 50-100% of organisms sampled from specific phyla would evade detection in typical cultivation-independent surveys. CPR organisms often have self-splicing introns and proteins encoded within their rRNA genes, a feature rarely reported in bacteria. Furthermore, they have unusual ribosome compositions. All are missing a ribosomal protein often absent in symbionts, and specific lineages are missing ribosomal proteins and biogenesis factors considered universal in bacteria. This implies different ribosome structures and biogenesis mechanisms, and underlines unusual biology across a large part of the bacterial domain.

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Coevolution mechanisms that adapt viruses to genetic code variations implemented in their hosts
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Insights into the life of an oxygenic phototroph
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Role of Recombinant DNA Technology in Biofertilizer Production
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Microbiome: Current Status and Future Applications
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An Instrumental Environment for Metagenomic Analysis
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For the Future of Alkaliphiles: 50th Anniversary Year Since the Rediscovery of Alkaliphiles by Dr. Koki Horikoshi
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Analytic Methods in Microbiome Studies
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Precise correlation and metagenomic binning uncovers fine microbial community structure
Durno, W. E. (2017) · doi:10.14288/1.0348979 · Cited by 1
“Clustering methods have been used to inform on symbiotic relationships [40], genome isolations [65], and the tree of life [133].”
Method
Drivers of viral diversity and community compositional change over spatial and temporal scales in coastal British Columbia
Gustavsen, J. A. (2016) · doi:10.14288/1.0300438 · Cited by 1
“Amplicon sequencing andmetagenomic eorts directed towards marine bacteria (using the 16S rRNA gene) have revealed the possibility of more bacterial species than previously recognized (Sogin et al., 2006; Brown et al., 2015).”
BackgroundInfluential
Novel Microorganisms and Their Function on Anaerobic Digesters
Kirkegaard, R. (2016) · doi:10.5278/vbn.phd.engsci.00180 · Cited by 1
“The sequences deposited in the reference databases are mostly PCR derived and it is thus likely that the conservation of primer sites is overestimated (Brown et al., 2015).”
Background
Microbial life deep underground: From anaerobic cultures to reconstructed genomes
Westmeijer, G. (2024) · doi:10.15626/lud.516.2023
Stream–lake network position structures freshwater microbial communities across multiple catchments
Kirtane, A. A., Deiner, K., & Hall, A. R. (2026) · bioRxiv · doi:10.64898/2026.10.29.762755
“In contrast, stream cores included nitrifying and redox-associated taxa such as Nitrospira (Daims et al., 2015), freshwater methylotrophs such as Methylotenera (Kalyuzhnaya et al., 2012), soil-associated genera including Cellvibrio (DeBoy et al., 2008), and groundwater-linked candidate phyla radiation lineages such as…”
A life-history axis of resource acquisition in bacteria: depolymerisation versus uptake
Fu, Y.-Y., Rodriguez, L. C., Ramoneda, J., Shek, K. L., Martiny, J. B., Allison, S. D., Luo, Y., & Malik, A. A. (2026) · bioRxiv · doi:10.64898/2026.10.25.761621
Reconstructing spore evolution recalibrates the timescale of land plant diversification.
Hooper, J., Worth, A. M., Wellman, C. H., Clark, J. W., & Donoghue, P. C. J. (2026) · Nature Plants · doi:10.1038/s41477-026-02432-3
Host Cell Wall Polysaccharides Modulate Nanosynbacteria Recognition and Attachment
Grossman, A. S., Souza, J. G., Lei, L., Anochshenko, K., Xia, M.-Y., Wang, Y.-X., Reyre, J.-L., Lowe, E. C., He, X.-S., Moynihan, P. J., et al. (2026) · bioRxiv · doi:10.64898/2026.10.06.756255
Conserved Hydrocarbon Degradation Architectures in Petroleum-Associated Microbiomes Revealed by Genome-Resolved Analysis Using the Petroleum-Associated Genome Database (PaGeD)
Hidalgo-Martinez, K., dos Santos, R. A. C., Novoletti, J. V. L., Capelini, T. D. L., Oliveira, A. L. M., Riaño-Pachón, D., Zafra, G., de Sousa, M. D., Martins, L. F., & de Oliveira, V. D. (2026) · Microorganisms · doi:10.3390/microorganisms14102197
“Interestingly, nearly 3% of the genomes were affiliated with the recently proposed Patescibacteria phylum [36], with greater prevalence in activated sludge, wastewater, and tailing ponds (Figure S3).”
Microbial ecology of shallow groundwater ecosystems.
Karwautz, C., & Griebler, C. (2026) · Nature Reviews Microbiology · doi:10.1038/s41579-026-01362-3
Single-Cell Genomics Uncovers an Unexpectedly Abundant, Phylogenetically Hyperdiverse Patescibacteria (Candidate Phyla Radiation) Community in Agricultural Paddy Soil
Ali, A., Saisho, D., Mochida, K., & Tani, A. (2026) · Microorganisms · doi:10.3390/microorganisms14102213
“Patescibacteria have repeatedly been reported at high relative abundance in subsurface and groundwater environments [14,50,51], providing an important point of reference for the patterns observed here.”
A hidden archaeal lineage with an ultra-reduced genome retaining only its replicative core
Harada, R., Nishimura, Y., Nomura, M., Yabuki, A., Shiba, K., Inaba, K., Allers, T., Inagaki, Y., & Nakayama, T. (2026) · Current Biology · doi:10.1016/j.cub.2026.09.042 · Cited by 9
Deep microbial biosphere.
Beaver, R. C., & Neufeld, J. D. (2026) · Current Biology · doi:10.1016/j.cub.2026.03.074
Extensive horizontal gene transfer drives microbial adaptation and diversification in Kermadec Trench hadal microbiomes
Liu, P.-Y., Lv, Y.-X., Zhang, Y., Wang, Y.-Z., Zhu, K.-L., Cao, Z.-Y., Dong, L., Xiao, X., Pan, Y., & Li, J.-H. (2026) · Nature Communications · doi:10.1038/s41467-026-77994-z
“For Patescibacteria , quality metrics were based on marker gene sets 65 .”
A Saccharimonadia epibiont interacts with the polyphosphate-accumulating bacterium Candidatus Phosphoribacter in wastewater treatment plants
Hu, H.-F., Kitzinger, K., Nierychlo, M., Liu, L., Lopatina, A., Kristensen, J. M., Peces, M., Herbold, C., Dueholm, M. K. D., Speth, D., et al. (2026) · bioRxiv · doi:10.64898/2026.09.16.751625
Reservoir fluids versus produced water as proxies for oil reservoir microbiomes
Alibrandi, A., Plewka, J., Vuillemin, A., Bartholomäus, A., Primio, R. D., Probst, A. J., & Kallmeyer, J. (2026) · Metabarcoding and Metagenomics · doi:10.3897/mbmg.10.194096
“Length-filtered scaffolds were binned into MAGs using Abawaca (v. 1.0.0; Brown et al. 2015) and MaxBin2 (v. 2.2.7; Wu et al. 2016) with default parameters, bins were aggregated with DASTool (v. 1.1.6; Sieber et al. 2018), and the resulting selection was manually curated with uBin (v. 0.9.14;…”
Influential
Groundwater microbial community structure under contrasting hydrological conditions in a sulfate-rich karst aquifer
Romano, R., Morita, T., Peres, F., Lizárraga, R., Padoan, L., Nascimento, M., Rocha, L., Bendia, A., Karmann, I., & Pellizari, V. (2026) · Frontiers in Microbiology · doi:10.3389/fmicb.2026.1883366
“…is now recognized as one of the deﬁning evolutionary features of the CPR radiation and has been consistently reported across phylogenetically diverse lineages occupying groundwater, subsurface and sedimentary environments (Brown et al., 2015; Castelle and Banﬁeld, 2018; Tian et al., 2020).”
Influential
A host-encoded prophage targets a Candidate Phyla Radiation bacterium and shapes episymbiotic interactions
Kumar, A., Nahar, N., Chouhan, D., McLean, J. S., Bor, B., Dong, P.-T., & He, X.-S. (2026) · Proceedings of the National Academy of Sciences of the United States of America · doi:10.1073/pnas.2615890123
Spatial heterogeneity in microbial community assembly and predicted functional profiles of sandstone microbiota from the Tianlongshan Grottoes
Liu, Z., Zheng, M.-Y., Ren, Y.-B., Wu, P.-C., Song, Y., Pei, Y.-L., Ma, M., Feng, Z.-H., & Jia, T. (2026) · International Biodeterioration & Biodegradation · doi:10.1016/j.ibiod.2026.106445
Serum physiology, fecal microbiota, and metabolome signatures associated with perinatal stage transitions in Mongolian mares
Liu, Y.-Y., He, Q.-Q., Wang, G., Wu, Z.-Y., Du, M., Bai, D.-Y., Dugarjaviin, M., & Zhang, X.-Z. (2026) · Frontiers in Veterinary Science · doi:10.3389/fvets.2026.1922191
“Candidatus_Saccharimonas , a representative genus of the Candidate Phyla Radiation (CPR) group Patescibacteria , is a specialized ﬁber-degrading taxon enriched in the EL period (66–68).”
Heatwave exposure and gastrointestinal and liver diseases: complementary evidence from a population-based study and animal experiments
Du, Y., Wu, M., Wu, H., Wu, Y., Fang, C., Li, L., Zhang, H.-T., & Wang, Y. (2026) · Frontiers in Physiology · doi:10.3389/fphys.2026.1883010
“…, although less studied, have recently been reported to show increased abundance in colorectal cancer and liver ﬁ brosis, suggesting that these underexplored taxa may also contribute to host metabolic dysregulation and immune perturbation (Brown et al., 2015; Wong and Yu, 2019; Iwaki et al., 2021).”
Phosphorus source shapes rhizosphere microbiome assembly and plant oxidative stress regulation in a volcanic Andisol: a path-analysis approach.
Barra, P., Parra-Almuna, L., Pontigo, S., Paredes, C., Larama, G., Valdebenito, D., Jerez-Quezada, C., Menezes-Blackburn, D., & Mora, M. D. L. L. (2026) · Plant physiology and biochemistry : PPB · doi:10.1016/j.plaphy.2026.111618
Root metabolite profiles support a chemical-trophic filtering hypothesis for genotype- and stage-specific rhizosphere assembly in chicory
Leclercq, L., Kientz, G., Lloret, E., Palaric, C., Taminiau, B., Daube, G., Molinié, R., Fontaine, J.-X., Mathiron, D., Drider, D., et al. (2026) · Frontiers in Microbiology · doi:10.3389/fmicb.2026.1855632
Development of an integrated workflow (NosZRef) for rapid and accurate nosZ gene profiling and its application to oceanic ecosystems.
Zhang, B.-S., Wang, X., Kuang, C.-Y., Wu, J.-P., & Hong, Y.-G. (2026) · Marine Environmental Research · doi:10.1016/j.marenvres.2026.108247
Metagenomics indicates new taxa in Candidatus Saccharimonadia and proposal of Parviradicicola hetaonensis gen. nov. sp. nov. and Parviputeicola dengkouensis gen. nov. sp. nov. following the rules of the SeqCode.
Wang, Y., Ye, L., Cao, C., Che, G., Zhang, C.-Z., Wei, Q., Hong, Y., & Jiang, K. (2026) · Systematic and Applied Microbiology · doi:10.1016/j.syapm.2026.126751
Multi-compartment denitrifying bioreactor for aquaculture tailwater treatment: Synergistic effects of temperature, HRT and nitrate loading on nitrogen removal and microbial community.
Sun, Y., Tang, J., Jia, L., Sun, X., Huang, Z.-T., Li, M.-Z., & Yang, X.-H. (2026) · Water Research · doi:10.1016/j.watres.2026.126588
Tryptophan became part of the universal genetic code post-LUCA
Wehbi, S., Ly-Trong, N., Wheeler, A. L., Bui, M., Lauretta, D., & Masel, J. (2026) · bioRxiv · doi:10.64898/2026.05.28.728509
“Wehbi et al. 8 also classified 2234 modern clans, for which all Pfams emerged in a single prokaryotic supergroup, using previously classified supergroups 61,81-83 .”
Multi-Year Biofilm Formation on Granitic Surfaces Reveals Dynamic Microbial Communities in Fennoscandian Shield Deep Groundwaters
Ståhle, M., Johnson, A., Turner, S., Mårtensson, P., Kalinowski, B., & Dopson, M. (2026) · Microbial Ecology · doi:10.1007/s00248-026-02812-4
“The BM004 family (Desulfobacterota) is from the order Desulfobulbales that mostly encompasses sulfate reducing bacteria [ 52] and along with UBA2206 have been identified in groundwaters [53 , 54 ].”
Museum specimens reveal evolutionary drivers and functions of oral microbiome in mammalsPreprint
Moraitou, M., Rozwalak, P., Richards, J., Saliari, K., Gillissen, E., Timmons, Z., Kitchener, A. C., Pauwels, O. S. G., Sabin, R., Kokkini, P., et al. (2026) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.64898/2026.06.19.733412 · Cited by 2
The ultrasmall ocean microbiome: a reservoir of microbial diversity and nitrogen fixation
Hollerer, C., Miravet-Verde, S., Ustick, L. J., Bork, P., Acinas, S., Pelletier, E., Sunagawa, S., & Bowler, C. (2026) · bioRxiv · doi:10.64898/2026.06.16.732551
“…Nanoarchaeota, and Nanohaloarchaeota) and the Patescibacteria (also known as Candidate Phyla Radiation, CPR), are both known to include lineages with ultrasmall cell sizes (100–400 nm) 7,8 , and are characterized by highly reduced genomes and symbiotic or host-dependent lifestyles 7–13 .”
A Novel Pilus System in Candidate Phyla Radiation BacteriaPreprint
Troman, L. A., Kim, J., Rose, J. J. A., Johnson, M. D., Banfield, J., Petrovski, S., & Ghosal, D. (2026) · bioRxiv · doi:10.64898/2026.03.03.709456
“The advancement of high-throughput sequencing and genome-resolved metagenomics led to the recognition of Candidate Phylum Radiation (CPR) bacteria and prediction of their symbiotic lifestyles (1, 2).”
Self-citation
The Elusive Fraction of Marine Plankton Diversity: Size, Abundance and Taxonomic Composition of 0.2 μm‐Filterable Prokaryotes Across Three Contrasting Coastal Environments
Ruiz-González, C., Andrés-Barrao, C., Lanzén, A., Alonso-Sáez, L., Ducklow, H. W., Gasol, J., & Morán, X. A. G. (2026) · Molecular Ecology · doi:10.1111/mec.70434
Metagenome-guided substrate selection enriches Terriglobus, reveals co-occurring taxa, and enables isolation of a novel speciesPreprint
Chiniquy, D., Diamond, S., Carlson, H. K., Kazakov, A., Coleman-Derr, D., Northen, T., Banfield, J., & Deutschbauer, A. (2026) · bioRxiv · doi:10.64898/2026.05.14.725246
“The association of CAZyme-poor taxa with Terriglobus could reflect: (i) vitamin/cofactor exchange that relieves auxotrophies [15,16,97], (ii) removal or detoxification of inhibitory intermediates generated during polymer turnover [88], and/or (iii) spatial or metabolic niche partitioning that…”
Self-citation
Current Understanding of Taxonomy and Ecology of the Phylum Minisyncoccota
Fujii, N., Nakajima, M., Narihiro, T., Kuroda, K., & Kindaichi, T. (2026) · Microbes and Environments · doi:10.1264/jsme2.me25084
“Additional lineages, such as Kazan and SM2F11, were also reported, but without prior documentation linking them to Patescibacteria .”
Influential
Single-cell transcriptomics reveals lateral transfers of multiple functional genes from prokaryotes to free-living ciliated protists in detrital food webs
Zhang, Q., Gentekaki, E., Leger, M. M., Zou, S., Zhang, G.-A.-T., Omar, A., Fu, Y., & Gong, J. (2026) · Marine Life Science & Technology · doi:10.1007/s42995-026-00382-5 · Cited by 1
“2; Supplementary Table S4)—largely uncultured microbial lineages known primarily through molecular data (Brown et al. 2015; Liu et al. 2022; Murug-kar et al. 2020; Rinke et al. 2013).”
Severe periodontitis patients with well-controlled type 2 diabetes display a distinct subgingival microbiome with increased Saccharibacteria compared to systemically healthy controls
Shi, S., Wang, S.-Y., Li, S.-Y., Lu, R.-F., Pan, S.-X., Chen, F., & He, X.-S. (2026) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2026.1814983
“…our data revealed between the two groups a signi ﬁ cant difference in the relative abundance of those non-conventional bacteria, such as Saccharibacteria and SR1, which have long been considered microbial “ dark matter ” with limited cultured representatives (Brown et al., 2015; Hug et al., 2016).”
Comparative genomics of Sphingomonas from the cupuassu (Theobroma grandiflorum) phyllosphere reveals signatures of host adaptation and beneficial interactions
da Silva, A. K., de Paula, C. H., de Matos, J. P., Ribeiro, D. F., Cordeiro, I. F., Lemes, C. G. D. C., Sanchez, A. B., Garcia, C. C. M., de Abreu, V. D., Alves, R. M., et al. (2026) · Symbiosis · doi:10.1007/s13199-026-01124-y
“This emphasizes the value of genome-resolved metagenomics for uncovering novel microbial diversity in non-model tropical systems (Brown et al. 2015; Hug et al. 2016; Parks et al. 2017).”
Deep-sea siliceous sponges harbor distinct and functionally diverse microbiomes
Lane, K. R., Meyer, K. S., Collens, A. B., Leal, C. V., Collins, A. G., Herrera, S., & Hansel, C. M. (2026) · Applied and Environmental Microbiology · doi:10.1128/aem.01747-26
“Patescibacteria are ultrasmall and have symbiotic and parasitic relationships with bacterial hosts (115–117).”
Summer drought impacts micropredator abundance and microbial food web structure in a rewetted fen peatland
Hu, D., Wang, H., Groß, V., Burns, A. M., & Urich, T. (2026) · ISME Communications · doi:10.1093/ismeco/ycag169
“Patescibacteria [ 28, 29].”
Metagenomics reveals potential interactions between Patescibacteriota and their phages in groundwater ecosystems
Hu, B., An, L.-Y., Wu, M., Xu, J.-B., Nie, Y., & Wu, X.-L. (2025) · mSystems · doi:10.1128/msystems.01204-25
“Based on three previous studies (7, 8, 11), a total of 82 groundwater metagenomic data sets were downloaded from NCBI Sequence Read Archive and NCBI BioSample databases (Data S1).”
Mapping the oral microbiome opens links to periodontitis.
Sempeck, C., & Olm, M. (2025) · Cell Host and Microbe · doi:10.1016/j.chom.2025.10.009
Growth of candidate phyla radiation bacteria in groundwater incubations reveals widespread adaptations to oxic conditions
Gabashvili, E., Küsel, K., Pratama, A. A., Wang, H., & Taubert, M. (2025) · Microbiome · doi:10.1186/s40168-025-02244-1
“Although its exact phylogenetic placement as one or multiple phyla is still debated, it represents a large fraction of bacterial diversity [3–6].”
Bacteria associated with the alga Ulva lactuca (Ulvaceae) from the Colombian Caribbean and their laccase activity
Millán-Aldana, N., González, N. C., & Vanegas, J. S. (2025) · Revista de Biología Tropical · doi:10.15517/8pkmas90
“Amplification of the 16S rRNA gene via PCR primers shows a bias towards certain taxa, resulting in the inability to detect others that could be identified using a metagenomic approach (Brown et al., 2015; Eloe-Fadrosh et al., 2016).”
Diverse but temporally stable virome in a 1.2 km deep karst aquifer accessed via Moab Khotsong mine, South Africa
Jobe, N. E., Jones, D. S., Hernandez, J. C., Nisson, D., Skaar, C. H., Onstott, T., & Kieft, T. (2025) · bioRxiv · doi:10.1101/2025.10.27.684889
“…the virome study at the Äspö hard rock laboratory include dominance of Pseudomonadota hosts and also of viruses infecting members of the candidate phyla radiation, now termed Patescibacteria , a group of divergent microorganisms first identified in an aquifer near Rifle, Colorado in the U.S. [67].”
ChloroScan: Recovering Plastid Genome Bins From Metagenomic Data
Tong, Y., Marcelino, V., Turnbull, R., & Verbruggen, H. (2025) · Molecular Ecology Resources · doi:10.1111/1755-0998.70143
Diving into borpung hot spring: microbial diversity, sediment characteristics, and potential for lignocellulolytic thermozymes
Boruah, J. L. H., Borah, B., Yadav, A., Gogoi, P., Dutta, P., Goswami, M., Dasgupta, A., Gogoi, P., Sarma, R. K., Debnath, R., et al. (2025) · International Journal of Environmental Science and Technology · doi:10.1007/s13762-025-06769-8
“Syntrophorhabdus and Candidate Division OD1 are syntrophic bacteria and engage in interspecies hydrogen and acetate transfer with methanogens, optimizing energy yield from complex substrates under thermophilic, anoxic conditions (Brown et al. 2015).”
Forest type and stand structure influence soil microbial network composition and stability in urban forests: Insights from Beijing, China
Zhu, J., Li, Z., Han, C.-H., Ma, L., Liu, X.-J., Qin, Y., & Yang, Y.-Z. (2025) · Urban Forestry & Urban Greening · doi:10.1016/j.ufug.2025.129062
A prevalent huge phage clade in human and animal gut microbiomes
Chen, L.-X., Qin, Y., Duan, Y., Li, H., Koonin, E., Camargo, A. P., Wang, H.-Y., & Zou, Y.-Q. (2025) · Research Square · doi:10.21203/rs.3.rs-7356405/v1
“They have a genome size of 540-660 kbp, which is comparable to that of some prokaryotes 37 , and were detected mostly in gut metagenomes of humans on non-Western diets as well as various animals 35,36 .”
A prevalent huge phage clade in human and animal gut microbiomes
Chen, L.-X., Camargo, A. P., Qin, Y., Koonin, E., Wang, H.-Y., Zou, Y.-Q., Duan, Y., & Li, H. (2025) · bioRxiv · doi:10.1101/2025.08.10.669567
“They have a genome size of 540-660 kbp, which is comparable to that of some prokaryotes 37 , and were detected mostly in gut metagenomes of humans on non-Western diets as well as various animals 35,36 .”
A silent sulfonamide-resistant microbial world: the curious case of missing DHPS in candidate phyla radiation.
Razzouk, R., Azour, A., Rolain, J., & Bittar, F. (2025) · Journal of Global Antimicrobial Resistance · doi:10.1016/j.jgar.2025.06.024
Metagenomic analysis of pristine oil sheds new light on the global distribution of microbial genetic repertoire in hydrocarbon-associated ecosystems
Plewka, J., Alibrandi, A., Bornemann, T., Esser, S., Stach, T., Sures, K., Becker, J., Moraru, C., Soares, A., Primio, R. D., et al. (2025) · microLife · doi:10.1093/femsml/uqae027
Carbon and microbes in a degrading palsa mire are distinct from a peatland and a wider connected sub-Arctic fluvial system
Tuomela, N., Elovaara, S., Hultman, J., Kaartokallio, H., & Thomas, D. N. (2025) · ISME Communications · doi:10.1093/ismeco/ycaf240 · Cited by 1
“While this bacterial phylum is relatively unknown, it has been detected in high abundances in, e.g. groundwater [87, 88] wastewaters [89] and thermokarst ponds [35, 40].”
Microbial Communities of Bottom Sediments of Alas Lakes of Central Yakutia as Indicators of Agricultural Load
Samylina, O., Gabyshev, V., Kosyakova, A. I., Kadnikov, V. V., Beletsky, A., & Pimenov, N. (2024) · Microbiology · doi:10.1134/s0026261724609813
“The presumed physiology of “ Candidatus Patescibacteria” is based solely on metagenomic data (Brown et al., 2015; Anantharaman et al., 2016; Castelle et al., 2018; Tian et al., 2020).”
First detection of fungal diversity associated with Prunus salicina Lindl malformation syndrome
Huang, D., Pu, P., He, X., Lan, M., Du, B., Zhu, L., Li, Q., Yang, Y., Xiang, R., Wang, L., et al. (2024) · All Life · doi:10.1080/26895293.2024.2417460

Authors: Brown, C. T., Hug, L. A., Thomas, B. C., Sharon, I., Castelle, C. J., Singh, A., Wilkins, M. J., Wrighton, K. C., Williams, K. H., & Banfield, J. F.
Affiliations: University of California, Berkeley (US)
The Ohio State University (US)
Lawrence Berkeley National Laboratory (US)
Corresponding author: Banfield, Jillian F.
ORCID: Brown, Christopher T.
Hug, Laura A.
Thomas, Brian C.
Sharon, Itai
Castelle, Cindy J.
Wilkins, Michael J.
Wrighton, Kelly C.
Williams, Kenneth H.
Banfield, Jillian F.
Venue: Nature
Publisher: Springer Science and Business Media LLC
Published: 2015-06-15
Volume: 523
Issue: 7559
Pages: 208-211
ISSN: 0028-0836 (ISSN-L)
1476-4687
DOI: 10.1038/nature14486
OpenAlex: W1528357204
Cited by: 1,216
References: 63
Citations by year: 2026: 56 · 2025: 100 · 2024: 95 · 2023: 125 · 2022: 108 · 2021: 120 · 2020: 144 · 2019: 121 · 2018: 116 · 2017: 104 · 2016: 101 · 2015: 26
FWCI: 50.17
Type: journal article
Language: en
Open access: green
www.osti.gov
Licence: www.springer.com/tdm (tdm)
Locations: Nature (publishedVersion)
PubMed (publishedVersion)
OSTI OAI (U.S. Department of Energy Office of Scientific and Technical Information) (submittedVersion)
RePEc: Research Papers in Economics (submittedVersion)
eScholarship (California Digital Library) (submittedVersion)
Funders: U.S. Department of Energy (DESC0004918, DE AC02 05CH11231)
Joint Genome Institute
Office of Science
Biological and Environmental Research
Pacific Northwest National Laboratory
Topics: Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Genomics and Phylogenetic Studies
Physical Sciences › Environmental Science › Ecology › Microbial Community Ecology and Physiology
Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Bacterial Genetics and Biotechnology
Keywords: Candidate Phyla Radiation, uncultured bacteria, bacterial evolution, ribosome composition, ribosome biogenesis, self-splicing introns, small genomes, groundwater bacteria, metagenome-assembled genomes, symbionts
MeSH terms: Bacteria, Environmental Microbiology, Introns, Phylogeny, Ribosomal Proteins, RNA, Ribosomal, 16S, Genome, Bacterial

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Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

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Unusual biology across a group comprising more than 15% of domain Bacteria

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cites

Cited by

Metadata

Record

About these checks