High-frequency off-target mutagenesis induced by CRISPR-Cas nucleases in human cells

Cited by (1,023)

Items 501–600 of 1,023

1. mlDEEPre: Multi-Functional Enzyme Function Prediction With Hierarchical Multi-Label Deep Learning
   Zhenzhen Zou, Shuye Tian, Xin Gao, Yu Li · 2019 · Frontiers in Genetics
2. Prime Editing in the model plant Physcomitrium patens and its potential in the tetraploid potato
   Pierre‐François Perroud, Anouchka Guyon‐Debast, Florian Veillet, Marie-Paule Kermarrec, Laura Chauvin, Jean-Éric Chauvin, Jean‐Luc Gallois, Fabien Nogué · 2021 · Plant Science
3. AAV-Mediated Delivery of Zinc Finger Nucleases Targeting Hepatitis B Virus Inhibits Active Replication
   Nicholas D. Weber, Daniel Stone, Ruth Hall Sedlak, Harshana S. De Silva Feelixge, Pavitra Roychoudhury, Joshua Tisdell Schiffer, Martine Aubert, Keith R. Jerome · 2014 · PLoS ONE
4. CRISPR ‐Cas9‐mediated efficient directed mutagenesis and RAD 51‐dependent and RAD 51‐independent gene targeting in the moss Physcomitrella patens
   Cécile Collonnier, Aline Epert, Kostlend Mara, François Maclot, Anouchka Guyon‐Debast, Florence Charlot, Charles I. White, Didier G. Schaefer, Fabien Nogué · 2016 · Plant Biotechnology Journal
5. Precision Control of CRISPR-Cas9 Using Small Molecules and Light
   Soumyashree A. Gangopadhyay, Kurt J. Cox, Debasish Manna, Donghyun Lim, Basudeb Maji, Qingxuan Zhou, Amit Choudhary · 2019 · Biochemistry
6. Evaluation and Reduction of CRISPR Off-Target Cleavage Events
   Christopher A. Vakulskas, Mark A. Behlke · 2019 · Nucleic Acid Therapeutics
7. Delivering Cas9/sgRNA ribonucleoprotein (RNP) by lentiviral capsid-based bionanoparticles for efficient ‘hit-and-run’ genome editing
   Pin Lyu, Parisa Javidi-Parsijani, Anthony Atala, Baisong Lu · 2019 · Nucleic Acids Research
8. Genome editing and its applications in genetic improvement in aquaculture
   Zituo Yang, Yepin Yu, Yi Xuan Tay, Gen Hua Yue · 2021 · Reviews in Aquaculture
9. CAR-T cell manufacturing landscape—Lessons from the past decade and considerations for early clinical development
   Juliana Dias, John García, Giulia Agliardi, Claire Roddie · 2024 · Molecular Therapy — Methods & Clinical Development
10. A simplified and efficient germline-specific CRISPR/Cas9 system forDrosophilagenomic engineering
    Zachary L. Sebo, Han B. Lee, Ying Peng, Yi Guo · 2013 · Fly
11. Enhanced integration of large DNA into E. coli chromosome by CRISPR/Cas9
    Mu‐En Chung, Yeh I-Hsin, Li‐Yu Sung, Mengying Wu, Yun‐Peng Chao, I‐Son Ng, Yu‐Chen Hu · 2016 · Biotechnology and Bioengineering
12. In Vitro Enzymology of Cas9
    Carolin Anders, Martin Jínek · 2014 · Methods in enzymology on CD-ROM/Methods in enzymology
13. Efficient, Complete Deletion of Synaptic Proteins using CRISPR
    Salvatore Incontro, Cédric S. Asensio, Robert H. Edwards, Roger A. Nicoll · 2014 · Neuron
14. VSV-G-Enveloped Vesicles for Traceless Delivery of CRISPR-Cas9
    Montagna, Claudia, Petris, Gianluca, Casini, Antonio, Maule, Giulia, Franceschini, Gian Marco, Zanella, Ilaria, Conti, Luciano, Arnoldi, Francesca, Burrone, Oscar R., Zentilin, Lorena et al. · 2018 · Molecular Therapy Nucleic Acids
15. Plant Genome Editing and the Relevance of Off-Target Changes
    Nathaniel D. Graham, Gunvant Patil, David M. Bubeck, Raymond C. Dobert, Kevin C. Glenn, Annie T. Gutsche, Sandeep Kumar, John A. Lindbo, Luis Maas, Gregory D. May et al. · 2020 · PLANT PHYSIOLOGY
16. CRISPR/Cas9-mediated genome engineering and the promise of designer flies on demand
    Scott J. Gratz, Jill Wildonger, Melissa M. Harrison, Kate M. O’Connor-Giles · 2013 · Fly
17. The pros and cons of vertebrate animal models for functional and therapeutic research on inherited retinal dystrophies
    Ralph W. N. Slijkerman, Fei Song, Galuh Astuti, Martijn A. Huynen, Erwin van Wijk, Knut Stieger, Rob W.J. Collin · 2015 · Progress in Retinal and Eye Research
18. CRISPR/Cas9 nickase-mediated disruption of hepatitis B virus open reading frame S and X
    Madina Karimova, Niklas Beschorner, Werner Dammermann, Jan Chemnitz, Daniela Indenbirken, Jan‐Hendrik Bockmann, Adam T. Grundhoff, Stefan Lüth, Frank Buchholz, Julian Schulze zur Wiesch et al. · 2015 · Scientific Reports
19. Allele-Specific CRISPR-Cas9 Genome Editing of the Single-Base P23H Mutation for Rhodopsin-Associated Dominant Retinitis Pigmentosa
    Pingjuan Li, Benjamin P. Kleinstiver, Mihoko Leon, Michelle S. Prew, Daniel Navarro-Gomez, Scott H. Greenwald, Eric A. Pierce, J. Keith Joung, Qin Liu · 2018 · The CRISPR Journal
20. Mutagenesis and homologous recombination in Drosophila cell lines using CRISPR/Cas9
    Andrew Roger Bassett, Charlotte Tibbit, Chris Paul Ponting, Ji‐Long Liu · 2013 · Biology Open
21. DNA-binding-domain fusions enhance the targeting range and precision of Cas9
    Mehmet Fatih Bolukbasi, Ankit Gupta, Sarah Oikemus, Alan G. Derr, Manuel G. Garber, Michael H Brodsky, Lihua Julie Zhu, Scot A. Wolfe · 2015 · Nature Methods
22. Fanconi Anemia Gene Editing by the CRISPR/Cas9 System
    Mark J. Osborn, Richard Gabriel, Beau R. Webber, Anthony P. DeFeo, Amber N. McElroy, Jordan Jarjour, Colby G. Starker, John E. Wagner, J. Keith Joung, Daniel F. Voytas et al. · 2014 · Human Gene Therapy
23. Metabolic Engineering of Probiotic Saccharomyces boulardii
    Jingjing Liu, In Iok Kong, Guo-Chang Zhang, Lahiru Niroshan Jayakody, Heejin Kim, Peng‐Fei Xia, Suryang Kwak, Bong Hyun Sung, Jung‐Hoon Sohn, Hanna E. Walukiewicz et al. · 2016 · Applied and Environmental Microbiology
24. CRISPR/Cas9 Genome-Editing System in Human Stem Cells: Current Status and Future Prospects
    Zhao Zhang, Yuelin Zhang, Fei Gao, Shuo Han, Kathryn S.E. Cheah, Hung‐Fat Tse, Qizhou Lian · 2017 · Molecular Therapy — Nucleic Acids
25. Hybridization Kinetics Explains CRISPR-Cas Off-Targeting Rules
    Misha Klein, Behrouz Eslami-Mossallam, Dylan Gonzalez Arroyo, Martin Depken · 2018 · Cell Reports
26. Genome-wide determination of on-target and off-target characteristics for RNA-guided DNA methylation by dCas9 methyltransferases
    Lin Lin, Yong Liu, Fengping Xu, Jinrong Huang, Tina Fuglsang Daugaard, Trine Skov Petersen, Bettina Dencker Hansen, Lingfei Ye, Qing Xiao Zhou, Fang Fang et al. · 2018 · GigaScience
27. Ultrasound-activated particles as CRISPR/Cas9 delivery system for androgenic alopecia therapy
    Jee‐Yeon Ryu, Eun-Jeong Won, Han A. Reum Lee, Jin Hyun Kim, Emmanuel Hui, Hong-Pyo Kim, Tae‐Jong Yoon · 2019 · Biomaterials
28. Engineering a far-red light–activated split-Cas9 system for remote-controlled genome editing of internal organs and tumors
    Yuanhuan Yu, Xin Wu, Ningzi Guan, Jiawei Shao, Huiying Li, Yuxuan Chen, Ping Yuan, Dali Li, Haifeng Ye · 2020 · Science Advances
29. Efficient production of biallelic GGTA 1 knockout pigs by cytoplasmic microinjection of CRISPR /Cas9 into zygotes
    Björn Petersen, Antje Frenzel, Andrea Lucas‐Hahn, Doris Herrmann, Petra Hassel, Sabine Klein, Maren Ziegler, Klaus‐Gerd Hadeler, Heiner Niemann · 2016 · Xenotransplantation
30. Complementary information derived from CRISPR Cas9 mediated gene deletion and suppression
    Joseph Rosenbluh, Han Xu, William Harrington, Stanley Gill, Xiaoxing Wang, Francisca Vázquez, David E. Root, Aviad Tsherniak, William C. Hahn · 2017 · Nature Communications
31. CRISPR/Cas9-mediated genome engineering of CHO cell factories: application and perspectives
    Lee, Jae Seong, Grav, Lise Marie, Lewis, Nathan E., Faustrup Kildegaard, Helene · 2015 · Biotechnology Journal
32. Precision cancer mouse models through genome editing with CRISPR-Cas9
    Haiwei Mou, Zachary Kennedy, Daniel G. Anderson, Hao Yin, Wen Xue · 2015 · Genome Medicine
33. Simple generation of albino C57BL/6J mice with G291T mutation in the tyrosinase gene by the CRISPR/Cas9 system
    Seiya Mizuno, Tra Thi Huong Dinh, Kanako Kato, Saori Mizuno‐Iijima, Yoko Tanimoto, Yoko Daitoku, Yoshikazu Hoshino, Masahito Ikawa, Satoru Takahashi, Fumihiro Sugiyama et al. · 2014 · Mammalian Genome
34. CRISPR-Cas12a delivery by DNA-mediated bioresponsive editing for cholesterol regulation
    Wujin Sun, Jinqiang Wang, Quanyin Hu, Xingwu Zhou, Ali Khademhosseini, Zhen Gu · 2020 · Science Advances
35. Tools for experimental and computational analyses of off-target editing by programmable nucleases
    Bao, X. Robert, Pan, Yidan, Lee, Ciaran M., Davis, Timothy H., Bao, Gang · 2021 · Nature Protocols
36. How specific is CRISPR/Cas9 really?
    Henriette O’Geen, Abigail S. Yu, David Jay Segal · 2015 · Current Opinion in Chemical Biology
37. Creating and evaluating accurate CRISPR-Cas9 scalpels for genomic surgery
    Mehmet Fatih Bolukbasi, Ankit Gupta, Scot A. Wolfe · 2015 · Nature Methods
38. A Biophysical Model of CRISPR/Cas9 Activity for Rational Design of Genome Editing and Gene Regulation
    Iman Farasat, Howard M. Salis · 2016 · PLoS Computational Biology
39. CRISPR/Cas9 therapeutics: a cure for cancer and other genetic diseases
    Faheem Ahmed Khan, Nuruliarizki Shinta Pandupuspitasari, Chunjie Huang, Zhou Ao, Muhammad Jamal, Ali Zohaib, Farhan Ahmed Khan, Muthia Raihana Hakim, Zhang ShuJun · 2016 · Oncotarget
40. Human-induced pluripotent stem cells: potential for neurodegenerative diseases
    Christopher A. Ross, Sergey Akimov · 2014 · Human Molecular Genetics
41. Genome Editing in Human Pluripotent Stem Cells: Approaches, Pitfalls, and Solutions
    Hendriks, William T., Warren, Curtis R., Cowan, Chad A. · 2016 · Cell Stem Cell
42. A Cas9 Variant for Efficient Generation of Indel-Free Knockin or Gene-Corrected Human Pluripotent Stem Cells
    Sara E. Howden, Bradley McColl, Astrid Glaser, Jim Vadolas, Steven Petrou, Melissa Helen Little, Andrew G. Elefanty, Edouard G. Stanley · 2016 · Stem Cell Reports
43. Editing the genome of hiPSC with CRISPR/Cas9: disease models
    Andrew Roger Bassett · 2017 · Mammalian Genome
44. Cell-type-specific genome editing with a microRNA-responsive CRISPR–Cas9 switch
    Moe Hirosawa, Yoshihiko Fujita, Callum Parr, Karin Hayashi, Shunnichi Kashida, Akitsu Hotta, Knut Woltjen, Hirohide Saito · 2017 · Nucleic Acids Research
45. Sclerostin and Osteocalcin: Candidate Bone-Produced Hormones
    Jialiang S. Wang, Courtney M. Mazur, Marc Nathan Wein · 2021 · Frontiers in Endocrinology
46. A glance at genome editing with CRISPR–Cas9 technology
    Antara Barman, Bornali Deb, Supriyo Chakraborty · 2019 · Current Genetics
47. Metabolic engineering of plant secondary metabolites: prospects and its technological challenges
    Asem Mipeshwaree Devi, Khomdram Khedashwori Devi, Premi Devi Pukhrambam, Moirangthem Lakshmipriyari Devi, Sudripta Das · 2023 · Frontiers in Plant Science
48. Forward and reverse mutagenesis in C. elegans
    Lena M. Kutscher · 2014 · WormBook
49. Modeling Human Severe Combined Immunodeficiency and Correction by CRISPR/Cas9-Enhanced Gene Targeting
    Chia‐Wei Chang, Yi-Shin Lai, Erik R. Westin, Alireza Khodadadi‐Jamayran, Kevin M. Pawlik, Lawrence S. Lamb, Frederick D. Goldman, Tim M. Townes · 2015 · Cell Reports
50. Mouse Genome Engineering via CRISPR-Cas9 for Study of Immune Function
    S. William Pelletier, Sébastien Gingras, Douglas R. Green · 2015 · Immunity
51. Genome editing: the road of CRISPR/Cas9 from bench to clinic
    Ayman Eid, Magdy M. Mahfouz · 2016 · Experimental & Molecular Medicine
52. CRISPR/Cas9 in zebrafish: an efficient combination for human genetic diseases modeling
    Jiaqi Liu, Yangzhong Zhou, Xiaolong Qi, Jia Chen, Wei‐Sheng Chen, Guixing Qiu, Zhihong Wu, Nan Wu · 2016 · Human Genetics
53. Biodegradable Amino-Ester Nanomaterials for Cas9 mRNA Delivery in Vitro and in Vivo
    Zhang, Xinfu, Li, Bin, Luo, Xiao, Zhao, Weiyu, Jiang, Justin, Zhang, Chengxiang, Gao, Min, Chen, Xiaofang, Dong, Yizhou · 2017 · ACS Applied Materials & Interfaces
54. CRISPR-based technologies: prokaryotic defense weapons repurposed
    Rebecca M. Terns, Michael P. Terns · 2014 · Trends in Genetics
55. Functional genetics for all: engineered nucleases, CRISPR and the gene editing revolution
    Anna F. Gilles, Michalis Averof · 2014 · EvoDevo
56. The use of induced pluripotent stem cells to reveal pathogenic gene mutations and explore treatments for retinitis pigmentosa
    Tetsu Yoshida, Yoko Ozawa, Keiichiro Suzuki, Kenya Yuki, Manabu Ohyama, Wado Akamatsu, Yumi Matsuzaki, Shigeto Shimmura, Kohnosuke Mitani, Kazuo Tsubota et al. · 2014 · Molecular Brain
57. Genome Editing Tools in Plants
    Tapan Kumar Mohanta, Tufail Bashir, Abeer Hashem, Elsayed Fathi Abd Allah, Hanhong Bae · 2017 · Genes
58. Lecithin nano-liposomal particle as a CRISPR/Cas9 complex delivery system for treating type 2 diabetes
    Eun Yi Cho, Jee‐Yeon Ryu, Han A. Reum Lee, Shin Hee Hong, Hye Sun Park, Kwan Soo Hong, Sanggyu Park, Hong-Pyo Kim, Tae‐Jong Yoon · 2019 · Journal of Nanobiotechnology
59. Optimizing genome editing strategy by primer-extension-mediated sequencing
    Jianhang Yin, Mengzhu Liu, Yang Liu, Jinchun Wu, Tingting Gan, Weiwei Zhang, Yinghui Li, Yaxuan Zhou, Jiazhi Hu · 2019 · Cell Discovery
60. Rationally engineered Staphylococcus aureus Cas9 nucleases with high genome-wide specificity
    Yuanyan Tan, Athena H. Y. Chu, Siyu Bao, Duc Anh Hoang, Firaol Tamiru Kebede, Wenjun Xiong, Mingfang Ji, Jiahai Shi, Zongli Zheng · 2019 · Proceedings of the National Academy of Sciences
61. CRISPR‐Net: A Recurrent Convolutional Network Quantifies CRISPR Off‐Target Activities with Mismatches and Indels
    Lin, Jiecong, Zhang, Zhaolei, Zhang, Shixiong, Chen, Junyi, Wong, Ka‐Chun · 2020 · Advanced Science
62. Cas9-Based Genome Editing in Xenopus tropicalis
    Takuya Nakayama, Ira L. Blitz, Margaret B. Fish, Akinleye O. Odeleye, Sumanth Manohar, Ken W.Y. Cho, Robert M. Grainger · 2014 · Methods in enzymology on CD-ROM/Methods in enzymology
63. Profiling single-guide RNA specificity reveals a mismatch sensitive core sequence
    Ting Zheng, Yingzi Hou, Pingjing Zhang, Zhenxi Zhang, Ying Ming Xu, Letian Zhang, Leilei Niu, Yi Qing Yang, Da Liang, Yi Fan et al. · 2017 · Scientific Reports
64. CRISPR/Cas9-Enabled Multiplex Genome Editing and Its Application
    Bastian Minkenberg, Matthew S. Wheatley, Yinong Yang · 2017 · Progress in molecular biology and translational science
65. Computational Tools and Resources for CRISPR/Cas Genome Editing
    Chao Li, Wen Chu, Rafaqat A. Gill, Shifei Sang, Yuqin Shi, Xuezhi Hu, Yuting Yang, Qamar U. Zaman, Baohong Zhang · 2022 · Genomics Proteomics & Bioinformatics
66. Patient-specific induced pluripotent stem cells (iPSCs) for the study and treatment of retinal degenerative diseases
    Luke A. Wiley, Erin R. Burnight, Allison E. Songstad, Arlene V. Drack, Robert F. Mullins, Edwin M. Stone, Budd A. Tucker · 2014 · Progress in Retinal and Eye Research
67. Targeted genome engineering in human induced pluripotent stem cells from patients with hemophilia B using the CRISPR-Cas9 system
    Cuicui Lyu, Jun Shen, Rui Wang, Haihui Gu, Jianping Zhang, Feng Xue, Xiao Fan Liu, Wei Liu, Rongfeng Fu, Liyan Zhang et al. · 2018 · Stem Cell Research & Therapy
68. Developments and opportunities in fungal strain engineering for the production of novel enzymes and enzyme cocktails for plant biomass degradation
    Roland S. Kun, Ana Carolina dos Santos Gomes, Kristiina Hildén, Sonia Salazar-Cerezo, Miia Mäkelä, Ronald P. de Vries · 2019 · Biotechnology Advances
69. CRISPR/Cas9 gene editing for curing sickle cell disease
    So Hyun Park, Gang Bao · 2021 · Transfusion and Apheresis Science
70. Modeling Disease In Vivo With CRISPR/Cas9
    Lukas E. Dow · 2015 · Trends in Molecular Medicine
71. The Conformational Dynamics of Cas9 Governing DNA Cleavage Are Revealed by Single-Molecule FRET
    Mengyi Yang, Sijia Peng, Ruirui Sun, Jingdi Lin, Nan Wang, Chunlai Chen · 2018 · Cell Reports
72. Harnessing Genome Editing Techniques to Engineer Disease Resistance in Plants
    Muntazir Mushtaq, Aafreen Sakina, Shabir Hussain Wani, Asif B. Shikari, Prateek Tripathi, Abbu Zaid, Aravind Galla, Mostafa Abdelrahman, Manmohan Sharma, Anil Kumar Singh et al. · 2019 · Frontiers in Plant Science
73. Modular one-pot assembly of CRISPR arrays enables library generation and reveals factors influencing crRNA biogenesis
    Chunyu Liao, Fani Ttofali, Rebecca Slotkowski, Steven R. Denny, Taylor D. Cecil, Ryan T. Leenay, Albert J. Keung, Chase L. Beisel · 2019 · Nature Communications
74. Friend or Foe? Evidence Indicates Endogenous Exosomes Can Deliver Functional gRNA and Cas9 Protein
    Ran Chen, Hongxin Huang, Hui Liu, Jingyuan Xi, Jing Ning, Wanjia Zeng, Congle Shen, Ting Zhang, Guangxin Yu, Qiang Xu et al. · 2019 · Small
75. CRISPR technologies for stem cell engineering and regenerative medicine
    Mu‐Nung Hsu, Yu‐Han Chang, Vu Anh Truong, Po‐Liang Lai, Thị Kieu Nuong Nguyen, Yu‐Chen Hu · 2019 · Biotechnology Advances
76. TCR Redirected T Cells for Cancer Treatment: Achievements, Hurdles, and Goals
    Francesco Manfredi, Beatrice Claudia Cianciotti, Alessia Potenza, Elena Tassi, Maddalena Noviello, Andrea Biondi, Fabio Ciceri, Chiara Bonini, Eliana Ruggiero · 2020 · Frontiers in Immunology
77. Catalytic Mechanism of Non-Target DNA Cleavage in CRISPR-Cas9 Revealed by Ab Initio Molecular Dynamics
    Lorenzo Casalino, Łukasz Nierzwicki, Martin Jínek, Giulia Palermo · 2020 · ACS Catalysis
78. Enabling functional genomics with genome engineering
    Isaac B. Hilton, Charles A. Gersbach · 2015 · Genome Research
79. Modularized Functions of the Fanconi Anemia Core Complex
    Yaling Huang, Justin W. C. Leung, Megan G. Lowery, Nobuko Matsushita, Yucai Wang, Xi Hua Shen, Huong Do, Minoru Takata, Junjie Chen, Lei Li · 2014 · Cell Reports
80. CRISPR/Cas9 for Human Genome Engineering and Disease Research
    Xin Xiong, Meng Chen, Wendell A. Lim, Dehua Zhao, Lei S. Qi · 2016 · Annual Review of Genomics and Human Genetics
81. Different Effects of sgRNA Length on CRISPR-mediated Gene Knockout Efficiency
    Jianping Zhang, Xiaolan Li, Amanda Neises, Wanqiu Chen, Linping Hu, Guangzhen Ji, Jun-Yao Yu, Jing Xu, Weiping Yuan, Tao Cheng et al. · 2016 · Scientific Reports
82. CRISPR/Cas9 system targeting regulatory genes of HIV-1 inhibits viral replication in infected T-cell cultures
    Youdiil Ophinni, Mari Inoue, Tomohiro Kotaki, Masanori Kameoka · 2018 · Scientific Reports
83. CRISPR ‐ PLANT v2: an online resource for highly specific guide RNA spacers based on improved off‐target analysis
    Bastian Minkenberg, Jianwei Zhang, Kabin Xie, Yinong Yang · 2018 · Plant Biotechnology Journal
84. Heat‐shock‐inducible CRISPR/Cas9 system generates heritable mutations in rice
    Soumen Nandy, Bhuvan P. Pathak, Shan Zhao, Vibha Srivastava · 2019 · Plant Direct
85. Generation of an ICF Syndrome Model by Efficient Genome Editing of Human Induced Pluripotent Stem Cells Using the CRISPR System
    Horii, Takuro, Tamura, Daiki, Morita, Sumiyo, Kimura, Mika, Hatada, Izuho · 2013 · International Journal of Molecular Sciences
86. Highly efficient targeted mutagenesis in axolotl using Cas9 RNA-guided nuclease
    Grant Parker Flowers, Andrew T. Timberlake, Kaitlin C. McLean, James R. Monaghan, Craig M. Crews · 2014 · Development
87. CRISPR interference and priming varies with individual spacer sequences
    Chaoyou Xue, Arun Somwarpet Seetharam, Olga S. Musharova, Konstantin Severinov, Stan J. J. Brouns, Andrew Josef Severin, Dipali G. Sashital · 2015 · Nucleic Acids Research
88. Toward an optimized process for clinical manufacturing of CAR-treg cell therapy
    Fritsche, Enrico, Volk, Hans-Dieter, Reinke, Petra, Abou-El-Enein, Mohamed · 2020 · Trends in Biotechnology
89. COL7A1 Editing via CRISPR/Cas9 in Recessive Dystrophic Epidermolysis Bullosa
    Stefan Hainzl, Patricia Peking, Thomas Köcher, Eva Maria Murauer, Fernando Larcher, Marcela Del Río, Blanca Duarte, Markus J. Steiner, Alfred Klausegger, Johann Wolfgang Bauer et al. · 2017 · Molecular Therapy
90. Genome Editing of Pigs for Agriculture and Biomedicine
    Huaqiang Yang, Zhenfang Wu · 2018 · Frontiers in Genetics
91. Heritable Genome Editing with CRISPR/Cas9 in the Silkworm, Bombyx mori
    Wei Wei, Huhu Xin, Bhaskar Roy, Junbiao Dai, Yun‐gen Miao, Guanjun Gao · 2014 · PLoS ONE
92. Generation and evaluation of Myostatin knock-out rabbits and goats using CRISPR/Cas9 system
    Rihong Guo, Yongjie Wan, Dan Xu, Libin Cui, Mingtian Deng, Guomin Zhang, Ruoxin Jia, Wenjun Zhou, Zhen Wang, Kaiping Deng et al. · 2016 · Scientific Reports
93. Genome Editing Technologies: Defining a Path to Clinic
    Jacqueline Corrigan‐Curay, Marina O’Reilly, Donald B. Kohn, Paula M. Cannon, Gang Bao, Frederic D. Bushman, Dana Carroll, Toni Cathomen, J. Keith Joung, David B. Roth et al. · 2015 · Molecular Therapy
94. Transgene-Free Genome Editing in Caenorhabditis elegans Using CRISPR-Cas
    Hui Chiu, Hillel T. Schwartz, Igor A. Antoshechkin, Paul W. Sternberg · 2013 · Genetics
95. Advancing chimeric antigen receptor T cell therapy with CRISPR/Cas9
    Jiangtao Ren, Yangbing Zhao · 2017 · Protein & Cell
96. Assessing and Exploiting Functional Diversity in Germplasm Pools to Enhance Abiotic Stress Adaptation and Yield in Cereals and Food Legumes
    Sangam Lal Dwivedi, Armin Scheben, David Edwards, Charles Spillane, Rodomiro Octavio Ortiz · 2017 · Frontiers in Plant Science
97. CRISPR-Cas9 Editing in Maize: Systematic Evaluation of Off-target Activity and Its Relevance in Crop Improvement
    Joshua K. Young, Gina Zastrow‐Hayes, Stéphane Deschamps, Sergei K. Svitashev, Mindaugas Zaremba, Ananta Acharya, Sushmitha Paulraj, Brooke D. Peterson-Burch, Chris S. Schwartz, Vesna Djukanovic et al. · 2019 · Scientific Reports
98. Cas9-edited immune checkpoint blockade PD-1 DNA polyaptamer hydrogel for cancer immunotherapy
    Jaiwoo Lee, Quoc‐Viet Le, Geon Yang, Yu‐Kyoung Oh · 2019 · Biomaterials
99. Challenges in delivery systems for CRISPR-based genome editing and opportunities of nanomedicine
    Victor Aaron Sioson, Minjong Kim, Jinmyoung Joo · 2021 · Biomedical Engineering Letters
100. Genome Editing Using Cas9 Nickases
     Alexandro E. Trevino, Feng Zhang · 2014 · Methods in enzymology on CD-ROM/Methods in enzymology