The DOI matches its Crossref record; 20 of the 21 references it cites were found in a registry or an index.
Nanoliter-scale synthesis of arrayed biomaterials and application to human embryonic stem cells
Abstract
Identification of biomaterials that support appropriate cellular attachment, proliferation and gene expression patterns is critical for tissue engineering and cell therapy. Here we describe an approach for rapid, nanoliter-scale synthesis of biomaterials and characterization of their interactions with cells. We simultaneously characterize over 1,700 human embryonic stem cell-material interactions and identify a host of unexpected materials effects that offer new levels of control over human embryonic stem cell behavior.
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“Synthetic polymer-based culture allows organoid formation conditions to be evaluated using high-throughput methods143–145.”
From Towards organoid culture without Matrigel (2021) · cites this paper as [145]
Citations
Cites
Embryonic Stem Cell Lines Derived from Human Blastocysts
Thomson, J. A., Itskovitz‐Eldor, J., Shapiro, S. S., Waknitz, M. A., Swiergiel, J. J., Marshall, V. S., & Jones, J. M. (1998) · Science · doi:10.1126/science.282.5391.1145 · Cited by 15,947
Quantitative Monitoring of Gene Expression Patterns with a Complementary DNA Microarray
Schena, M., Shalon, D., Davis, R. W., & Brown, P. O. (1995) · Science · doi:10.1126/science.270.5235.467 · Cited by 9,609
Moll, R., Franke, W. W., Schiller, D. L., Geiger, B., & Krepler, R. (1982) · Cell · doi:10.1016/0092-8674(82)90400-7 · Cited by 5,239
Printing Proteins as Microarrays for High-Throughput Function Determination
MacBeath, G., & Schreiber, S. L. (2000) · Science · doi:10.1126/science.289.5485.1760 · Cited by 2,767
Role of cell shape in growth control
Folkman, J., & Moscona, A. (1978) · Nature · doi:10.1038/273345a0 · Cited by 2,422
Serial passaging and differentiation of myogenic cells isolated from dystrophic mouse muscle
Yaffe, D., & Saxel, O. (1977) · Nature · doi:10.1038/270725a0 · Cited by 2,153
Principles of Tissue Engineering
(2014) · Elsevier eBooks · doi:10.1016/c2011-0-07193-4 · Cited by 1,912
Spradling, A. C., Drummond‐Barbosa, D., & Kai, T. (2001) · Nature · doi:10.1038/35102160 · Cited by 1,465
Endothelial cells derived from human embryonic stem cells
Levenberg, S., Golub, J. S., Amit, M., Itskovitz‐Eldor, J., & Langer, R. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.032074999 · Cited by 818
Self-citationDifferentiation of human embryonic stem cells on three-dimensional polymer scaffolds
Levenberg, S., Huang, N. F., Lavik, E., Rogers, A. B., Itskovitz‐Eldor, J., & Langer, R. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1735463100 · Cited by 691
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1 of the 21 references couldn’t be matched to a known paper.
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Liu, Y., Ai, K., & Lu, L. (2014) · Chemical Reviews · doi:10.1021/cr400407a · Cited by 4,794
Lutolf, M. P., & Hubbell, J. A. (2005) · Nature Biotechnology · doi:10.1038/nbt1055 · Cited by 4,551
Hydrogels in regenerative medicine
Slaughter, B. V., Khurshid, S. S., Fisher, O. Z., Khademhosseini, A., & Peppas, N. A. (2009) · Advanced Materials · doi:10.1002/adma.200802106 · Cited by 2,703
Growth Factors, Matrices, and Forces Combine and Control Stem Cells
Discher, D. E., Mooney, D. J., & Zandstra, P. W. (2009) · Science · doi:10.1126/science.1171643 · Cited by 2,666
Nanomedicine: current status and future prospects
Moghimi, S. M., Hunter, A. C., & Murray, J. C. (2005) · The FASEB Journal · doi:10.1096/fj.04-2747rev · Cited by 2,029
Metadata
- Authors
- Anderson, D. G., Levenberg, S., & Langer, R.
- Affiliations
- Massachusetts Institute of Technology (US)
- Venue
- Nature Biotechnology
- Published
- 2004-06-13
- Volume
- 22
- Issue
- 7
- Pages
- 863-866
- ISSN
- 0733-222X (ISSN-L)
- 1087-0156
- 1546-1696
- OpenAlex
- W2052098523
- Cited by
- 747
- References
- 21
- Citations by year
- 2026: 1 · 2025: 3 · 2024: 7 · 2023: 8 · 2022: 12 · 2021: 19 · 2020: 26 · 2019: 17 · 2018: 28 · 2017: 26 · 2016: 38 · 2015: 37 · 2014: 48 · 2013: 53 · 2012: 59
- FWCI
- 33.04
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Nature Biotechnology (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institutes of Health
- National Heart, Lung, and Blood Institute (HL 60435, R01HL060435)
- Topics
- Physical Sciences › Engineering › Biomedical Engineering › 3D Printing in Biomedical Research
- Health Sciences › Medicine › Surgery › Tissue Engineering and Regenerative Medicine
- Physical Sciences › Materials Science › Biomaterials › Hydrogels: synthesis, properties, applications
- Keywords
- human embryonic stem cells, cell-material interactions, biomaterials, tissue engineering, cell therapy, cell attachment, cell proliferation, gene expression
- MeSH terms
- Biocompatible Materials, Embryo, Mammalian, Humans, Polymers, Stem Cells, Combinatorial Chemistry Techniques, Microarray Analysis
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