Causes and consequences of replication stress
Zeman, Michelle K., Cimprich, Karlene A.·2014·Nature Cell Biology
DOI 10.1038/ncb2897
Cited by (1,001)
Items 101–200 of 1,001
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- Targeting DNA repair in cancer: current state and novel approachesApostolos Klinakis, Dimitris Karagiannis, Theodoros N Rampias · 2019 · Cellular and Molecular Life Sciences
- PTEN regulates RPA1 and protects DNA replication forksGuangxi Wang, Yang Li, Pan Wang, Hui Liang, Ming Cui, Minglu Zhu, Limei Guo, Qian Peter Su, Yujie Sun, Michael A. McNutt et al. · 2015 · Cell Research
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- DNA polymerase ε and its roles in genome stabilityErin E. Henninger, Zachary F. Pursell · 2014 · IUBMB Life
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