Causes and consequences of replication stress

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Items 301–400 of 1,001

1. Breaking the DNA damage response to improve cervical cancer treatment
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2. Bacterial Genotoxin-Induced DNA Damage and Modulation of the Host Immune Microenvironment
   Océane C. B. Martin, Teresa Frisan · 2020 · Toxins
3. DNA repair as a shared hallmark in cancer and ageing
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4. Short-term molecular consequences of chromosome mis-segregation for genome stability
   Lorenza Garribba, Giuseppina De Feudis, Valentino Martis, M. G. Galli, Marie Dumont, Yonatan Eliezer, René Wardenaar, Marica Rosaria Ippolito, Divya Iyer, Andréa E. Tijhuis et al. · 2023 · Nature Communications
5. ATRIP Deacetylation by SIRT2 Drives ATR Checkpoint Activation by Promoting Binding to RPA-ssDNA
   Hui Zhang, PamelaSara E. Head, Waaqo B. Daddacha, Seong‐Hoon Park, Xingzhe Li, Yunfeng Pan, Matthew Z. Madden, Duc Minh Duong, Maohua Xie, Bing Yu et al. · 2016 · Cell Reports
6. Polynucleotide kinase-phosphatase (PNKP) mutations and neurologic disease
   Lavinia C. Dumitrache, Peter J. McKinnon · 2017 · Mechanisms of Ageing and Development
7. PrimPol—Prime Time to Reprime
   Thomas A. Guilliam, Aidan J. Doherty · 2017 · Genes
8. Causes and consequences of genomic instability in laminopathies: Replication stress and interferon response
   Simona Graziano, Ray Kreienkamp, Núria Coll-Bonfill, Susana Gonzalo · 2018 · Nucleus
9. Uncoupling fork speed and origin activity to identify the primary cause of replicative stress phenotypes
   Sara Rodríguez‐Acebes, Silvana Andrea Mouron, Juan Méndez · 2018 · Journal of Biological Chemistry
10. Dynamics of Replication Fork Progression Following Helicase–Polymerase Uncoupling in Eukaryotes
    Martin R.G. Taylor, Joseph T.P. Yeeles · 2019 · Journal of Molecular Biology
11. Abro1 maintains genome stability and limits replication stress by protecting replication fork stability
    Shengfeng Xu, Xiao Y. Wu, Ling Wu, Andy Castillo, Jianxin Liu, Erin Atkinson, Atanu Paul, Dan Su, Katharina Schlacher, Yoshihiro Komatsu et al. · 2017 · Genes & Development
12. Updating the mechanisms of common fragile site instability: how to reconcile the different views?
    Benoît Le Tallec, Stéphane Koundrioukoff, Therese Wilhelm, Anne Letessier, Olivier Brison, Michelle Debatisse · 2014 · Cellular and Molecular Life Sciences
13. Complete loss of ATM function augments replication catastrophe induced by ATR inhibition and gemcitabine in pancreatic cancer models
    Charles R. Dunlop, Yann Wallez, Timothy Isaac Johnson, Sandra Bernaldo de Quirós Fernández, Stephen T. Durant, Elaine B. Cadogan, Alan Lau, Frances M. Richards, Duncan Ian Jodrell · 2020 · British Journal of Cancer
14. Global increase in replication fork speed during a p57 KIP2 -regulated erythroid cell fate switch
    Yung Hwang, Melinda Futran, Daniel Hidalgo, Ramona Pop, Divya Iyer, Ralph Scully, Nick Rhind, Merav Socolovsky · 2017 · Science Advances
15. The pathogenesis, diagnosis and management of congenital dyserythropoietic anaemia type I
    Noemi B. A. Roy, Christian Babbs · 2019 · British Journal of Haematology
16. WEE1 kinase protects the stability of stalled DNA replication forks by limiting CDK2 activity
    Elbæk, Camilla Reiter, Petrosius, Valdemaras, Benada, Jan, Erichsen, Louisa, Damgaard, Rune Busk, Sørensen, Claus Storgaard · 2022 · Cell Reports
17. More than Meets the ISG15: Emerging Roles in the DNA Damage Response and Beyond
    Zac Sandy, Isabelle Cristine da Costa, Christine K. Schmidt · 2020 · Biomolecules
18. Shaping the BRCAness mutational landscape by alternative double-strand break repair, replication stress and mitotic aberrancies
    Colin Stok, Yannick P. Kok, Nathalie van den Tempel, Marcel A.T.M. van Vugt · 2021 · Nucleic Acids Research
19. SUMO-Targeted Ubiquitin Ligases and Their Functions in Maintaining Genome Stability
    Ya‐Chu Chang, Marissa K. Oram, Anja‐Katrin Bielinsky · 2021 · International Journal of Molecular Sciences
20. CHK1 inhibitor sensitizes resistant colorectal cancer stem cells to nortopsentin
    Simone Di Franco, Barbara Parrino, Miriam Gaggianesi, Vincenzo Davide Pantina, Paola Bianca, Annalisa Nicotra, Laura Rosa Mangiapane, Melania Lo Iacono, Gloria Ganduscio, Veronica Veschi et al. · 2021 · iScience
21. High-affinity DNA-binding Domains of Replication Protein A (RPA) Direct SMARCAL1-dependent Replication Fork Remodeling
    Kamakoti P. Bhat, Rémy Betous, David Cortez · 2015 · Journal of Biological Chemistry
22. CHK1 Inhibition Synergizes with Gemcitabine Initially by Destabilizing the DNA Replication Apparatus
    Siang‐Boon Koh, Aurélie Courtin, Richard J. Boyce, Robert G. Boyle, Frances M. Richards, Duncan Ian Jodrell · 2015 · Cancer Research
23. Genomic rearrangements induced by unscheduled DNA double strand breaks in somatic mammalian cells
    Ayeong So, Tangui Le Guen, Bernard S. López, Josée Guirouilh‐Barbat · 2017 · FEBS Journal
24. Molecular mechanism and potential target indication of TAK-931, a novel CDC7-selective inhibitor
    Kenichi Iwai, Tadahiro Nambu, Ryo Dairiki, Momoko Ohori, Jie Yu, Kristine E. Burke, Masamitsu Gotou, Yukiko Yamamoto, Shunsuke Ebara, Sachio Shibata et al. · 2019 · Science Advances
25. Suppression of p16 Induces mTORC1-Mediated Nucleotide Metabolic Reprogramming
    Raquel Buj, Chi‐Wei Chen, Erika S. Dahl, Kelly E. Leon, Rostislav Kuskovsky, Natella Maglakelidze, Maithili Navaratnarajah, Gao Zhang, Mary T. Doan, Helen Jiang et al. · 2019 · Cell Reports
26. Human CST complex protects stalled replication forks by directly blocking MRE11 degradation of nascent‐strand DNA
    Xinxing Lyu, Kai-Hang Lei, Pau Biak Sang, Olga Shiva, M. Chastain, Peter Chi, Wei-Hang Chai · 2020 · EMBO Journal
27. Emerging strategies for cancer therapy by ATR inhibitors
    Kimiyoshi Yano, Bunsyo Shiotani · 2023 · Cancer Science
28. Role of Oxidative Stress in the Occurrence, Development, and Treatment of Breast Cancer
    Rui Dong, Jing Wang, Ruiqi Guan, Jianwei Sun, Ping Jin, Junling Shen · 2025 · Antioxidants
29. Interaction between the Rev1 C-Terminal Domain and the PolD3 Subunit of Polζ Suggests a Mechanism of Polymerase Exchange upon Rev1/Polζ-Dependent Translesion Synthesis
    Yulia E. Pustovalova, Mariana T. Q. de Magalhães, Sanjay D’Souza, Alessandro A. Rizzo, George Korza, Graham Charles Walker, Dmitry M. Korzhnev · 2016 · Biochemistry
30. Rescue from replication stress during mitosis
    Michalis Fragkos, Valeria Naim · 2017 · Cell Cycle
31. Checkpoint Kinase Rad53 Couples Leading- and Lagging-Strand DNA Synthesis under Replication Stress
    Haiyun Gan, Chuanhe Yu, Sujan Devbhandari, Sushma Sharma, Junhong Han, Andrei Chabes, Dirk Remus, Zhiguo Zhang · 2017 · Molecular Cell
32. Clinical use and mechanisms of resistance for PARP inhibitors in homologous recombination-deficient cancers
    Dawn C. Janysek, Jennifer S. Kim, Pascal H. G. Duijf, Eloise V. Dray · 2021 · Translational Oncology
33. Nonsense-Mediated RNA Decay Is a Unique Vulnerability of Cancer Cells Harboring SF3B1 or U2AF1 Mutations
    Abigael Cheruiyot, Shan Li, Sridhar Nonavinkere Srivatsan, Tanzir Ahmed, Yuhao Chen, Delphine Sangotokun Lemacon, Ying Li, Zheng Yang, Brian A. Wadugu, Wayne A. Warner et al. · 2021 · Cancer Research
34. Mechanisms and regulation of replication fork reversal
    Madison B. Adolph, David Cortez · 2024 · DNA repair
35. Translational research in radiation-induced DNA damage signaling and repair
    Jac A. Nickoloff, Mary‐Keara Boss, Chris Allen, Susan Μ. LaRue · 2017 · Translational Cancer Research
36. IncreasedRrm2gene dosage reduces fragile site breakage and prolongs survival of ATR mutant mice
    Andres Joaquin Lopez-Contreras, Julia Specks, Jacqueline H. Barlow, Chiara Ambrogio, Claus Desler, Svante Vikingsson, Sara Rodrigo-Perez, Henrik Gréen, Lene Juel Rasmussen, Matilde Murga et al. · 2015 · Genes & Development
37. The pendulum of the Ku-Ku clock
    Atsushi Shibata, Penny Ann Jeggo, Markus Löbrich · 2018 · DNA repair
38. Nascent DNA Proteomics Reveals a Chromatin Remodeler Required for Topoisomerase I Loading at Replication Forks
    Cyril Ribeyre, Ralph Zellweger, Maeva Y. Chauvin, Nicole Bec, Christian Larroque, Massimo Lopes, Angelos Constantinou · 2016 · Cell Reports
39. Mec1 Is Activated at the Onset of Normal S Phase by Low-dNTP Pools Impeding DNA Replication
    Romain Forey, Ana Poveda, Sushma Sharma, Antoine Barthe, Ismaël Padioleau, Claire Renard, Robin Lambert, Magdalena Skrzypczak, Krzysztof Ginalski, Armelle Lengronne et al. · 2019 · Molecular Cell
40. Chromatin mobility and relocation in DNA repair
    Noa Lamm, Samuel Rogers, Anthony J. Cesare · 2021 · Trends in Cell Biology
41. BAP1 as a guardian of genome stability: implications in human cancer
    Jongbum Kwon, Daye Lee, Shin-Ai Lee · 2023 · Experimental & Molecular Medicine
42. HPV31 utilizes the ATR-Chk1 pathway to maintain elevated RRM2 levels and a replication-competent environment in differentiating Keratinocytes
    Daniel C. Anacker, Heather L. Aloor, Caitlin Shepard, Gina M. Lenzi, Bryan A. Johnson, Baek Kim, Cary A. Moody · 2016 · Virology
43. Mechanisms responsible for the synergistic antileukemic interactions between ATR inhibition and cytarabine in acute myeloid leukemia cells
    Jun Ma, Xinyu Li, Yongwei Su, Jianyun Zhao, Daniel A Luedtke, Valeria Epshteyn, Holly J. Edwards, Guan Wang, Zhihong Wang, Roland L. Chu et al. · 2017 · Scientific Reports
44. One end to rule them all: Non-homologous end-joining and homologous recombination at DNA double-strand breaks
    Michael Ensminger, Markus Löbrich · 2020 · British Journal of Radiology
45. A small molecule inhibitor of the UBE2F-CRL5 axis induces apoptosis and radiosensitization in lung cancer
    Tiantian Xu, Qisheng Ma, Yanan Li, Qing Yu, Peichen Pan, Yawen Zheng, Zhijian Li, Xiufang Xiong, Tingjun Hou, Bin Yu et al. · 2022 · Signal Transduction and Targeted Therapy
46. HUWE1 interacts with PCNA to alleviate replication stress
    Katherine N. Choe, Claudia M. Nicolae, Daniel Constantin, Yuka Imamura Kawasawa, Maria Rocio Delgado‐Diaz, Subhajyoti De, Raimundo Freire, Veronique A. J. Smits, George‐Lucian Moldovan · 2016 · EMBO Reports
47. ATR-Chk1 activation mitigates replication stress caused by mismatch repair-dependent processing of DNA damage
    Dipika Gupta, Bo Lin, Ann E. Cowan, Christopher D. Heinen · 2018 · Proceedings of the National Academy of Sciences
48. SAMHD1 and the innate immune response to cytosolic DNA during DNA replication
    Flavie Coquel, Christoph Neumayer, Yi‐Ching Lin, Philippe Pasero · 2018 · Current Opinion in Immunology
49. KHDC3L mutation causes recurrent pregnancy loss by inducing genomic instability of human early embryonic cells
    Weidao Zhang, Zhongliang Chen, Dengfeng Zhang, Bo Zhao, Lu Liu, Zhengyuan Xie, Yong‐Gang Yao, Ping Zheng · 2019 · PLoS Biology
50. Nucleosides Rescue Replication-Mediated Genome Instability of Human Pluripotent Stem Cells
    Jason Alexander Halliwell, Thomas J.R. Frith, Owen Laing, Christopher J. Price, Oliver J. Bower, Dylan Stavish, Paul J. Gokhale, Zoë Hewitt, Sherif F. El‐Khamisy, Ivana Barbaric et al. · 2020 · Stem Cell Reports
51. Loss of Slug Compromises DNA Damage Repair and Accelerates Stem Cell Aging in Mammary Epithelium
    Gross, Kayla M., Zhou, Wenhui, Breindel, Jerrica L., Ouyang, Jian, Jin, Dexter X., Sokol, Ethan S., Gupta, Piyush B., Huber, Kathryn, Zou, Lee, Kuperwasser, Charlotte · 2019 · Cell Reports
52. Rad5 Recruits Error-Prone DNA Polymerases for Mutagenic Repair of ssDNA Gaps on Undamaged Templates
    David Gallo, Taehyung P. Kim, Barnabás Szakál, Xanita Saayman, Ashrut Narula, Yoona Park, Dana Branzei, Zhaolei Zhang, Grant W. Brown · 2019 · Molecular Cell
53. Mitotic DNA synthesis is caused by transcription-replication conflicts in BRCA2-deficient cells
    Florian J. Groelly, Rebecca A. Dagg, Michalis Petropoulos, Giacomo G. Rossetti, Birbal Prasad, Ανδρέας Παναγόπουλος, Teressa Paulsen, Angeliki Karamichali, Samuel E. Jones, Fena Ochs et al. · 2022 · Molecular Cell
54. Cytosolic DNA sensing by cGAS/STING promotes TRPV2-mediated Ca2+ release to protect stressed replication forks
    Shan Li, Lingzhen Kong, Ying Meng, Cheng Chen, Delphine Sangotokun Lemacon, Zheng Yang, Ke Tan, Abigael Cheruiyot, Zhimin Lu, Zhongsheng You · 2023 · Molecular Cell
55. APE2 Zf-GRF facilitates 3′-5′ resection of DNA damage following oxidative stress
    Bret D. Wallace, Zachary Berman, Geoffrey A. Mueller, Yunfeng Lin, Timothy H. Chang, Sara N. Andres, Jessica L. Wojtaszek, Eugene F. DeRose, C. Denise Appel, Robert E. London et al. · 2016 · Proceedings of the National Academy of Sciences
56. Role of RAD51AP1 in homologous recombination DNA repair and carcinogenesis
    Elena Pires, Patrick Sung, Claudia Wiese · 2017 · DNA repair
57. Emerging roles of CST in maintaining genome stability and human disease
    J. Stewart, Yi-Lin Wang, Stephanie M. Ackerson, P. L. Schuck · 2018 · Frontiers in Bioscience
58. Overexpression of the base excision repair NTHL1 glycosylase causes genomic instability and early cellular hallmarks of cancer
    Kristin L. Limpose, Kelly S. Trego, Zhentian Li, Sara W. Leung, Altaf Hossain Sarker, Jason A. Shah, Suresh S. Ramalingam, Erica Werner, William S. Dynan, Priscilla K. Cooper et al. · 2018 · Nucleic Acids Research
59. Rev7 dimerization is important for assembly and function of the Rev1/Polζ translesion synthesis complex
    Alessandro A. Rizzo, Faye-Marie Vassel, Nimrat Chatterjee, Sanjay D’Souza, Yunfeng Li, Bing Hao, Michael T. Hemann, Graham Charles Walker, Dmitry M. Korzhnev · 2018 · Proceedings of the National Academy of Sciences
60. Organelle DNA rearrangement mapping reveals U-turn-like inversions as a major source of genomic instability in Arabidopsis and humans
    Éric Zampini, Étienne Lepage, Samuel Tremblay‐Belzile, Sébastien Truche, Normand Brisson · 2015 · Genome Research
61. Synergistic lethality between BRCA1 and H3K9me2 loss reflects satellite derepression
    Jan Padeken, Peter J. Zeller, Benjamin D. Towbin, Iskra Katic, Véronique Kalck, Stephen P. Methot, Susan M. Gasser · 2019 · Genes & Development
62. Guidelines for DNA recombination and repair studies: Cellular assays of DNA repair pathways
    Hannah L. Klein, Giedrė Bačinskaja, Jun Che, Anaïs Cheblal, Rajula Elango, Anastasiya Epshtein, Devon M. Fitzgerald, Belén Gómez‐González, Sharik R. Khan, Sandeep Kumar et al. · 2019 · Microbial Cell
63. Hair follicle stem cell replication stress drives IFI16/STING-dependent inflammation in hidradenitis suppurativa
    Cindy Orvain, Yi‐Ching Lin, Francette Jean‐Louis, Hakim Hocini, Barbara Hersant, Yamina Bennasser, Nicolás Ortonne, Claire Hotz, P. Wolkenstein, Michele Boniotto et al. · 2020 · Journal of Clinical Investigation
64. PRIMPOL ready, set, reprime!
    Stephanie Tirman, Emily Cybulla, Annabel Quinet, Alice Meroni, Alessandro Vindigni · 2020 · Critical Reviews in Biochemistry and Molecular Biology
65. Paradoxical Activation of Oncogenic Signaling as a Cancer Treatment Strategy
    Matheus Henrique Dias, Anoek Friskes, Siying Wang, João M. Fernandes Neto, Frank P. A. van Gemert, Soufiane M. C. Mourragui, Chrysa Papagianni, Hendrik J. Kuiken, Sara Mainardi, Daniel Alvarez Villanueva et al. · 2024 · Cancer Discovery
66. DNA replication stress underlies renal phenotypes in CEP290-associated Joubert syndrome
    Gisela G.G. Slaats, Joshua C. Saldivar, Julien Bacal, Michelle K. Zeman, Andrew C. Kile, Ann Marie Hynes, Shalabh Srivastava, Jekaterina Nazmutdinova, Krista den Ouden, Miriam S. Zagers et al. · 2015 · Journal of Clinical Investigation
67. Tousled-like kinases stabilize replication forks and show synthetic lethality with checkpoint and PARP inhibitors
    Sung‐Bau Lee, Sandra Segura‐Bayona, Marina Villamor-Payà, Giulia Saredi, Matthew A. M. Todd, Camille Stephan‐Otto Attolini, Ting-Yu Chang, Travis H. Stracker, Anja Groth · 2018 · Science Advances
68. Application of the adverse outcome pathway framework to genotoxic modes of action
    Jennifer C. Sasaki, Ashley Allemang, Steven M. Bryce, Laura L. Custer, Kerry L. Dearfield, Yasmin Dietz, Azeddine Elhajouji, Patricia A. Escobar, Albert J. Fornace, Roland Frötschl et al. · 2019 · Environmental and Molecular Mutagenesis
69. TPP1 Blocks an ATR-Mediated Resection Mechanism at Telomeres
    Tatsuya Kibe, Michal Zimmermann, Titia de Lange · 2016 · Molecular Cell
70. Acute inactivation of the replicative helicase in human cells triggers MCM8–9-dependent DNA synthesis
    Toyoaki Natsume, Kohei Nishimura, Sheroy Minocherhomji, Rahul Bhowmick, Ian David Hickson, Masato T. Kanemaki · 2017 · Genes & Development
71. Hyperactive CDK2 Activity in Basal-like Breast Cancer Imposes a Genome Integrity Liability that Can Be Exploited by Targeting DNA Polymerase ε
    Sviderskiy, Vladislav O., Blumenberg, Lili, Gorodetsky, Elizabeth, Karakousi, Triantafyllia R., Hirsh, Nicole, Alvarez, Samantha W., Terzi, Erdem M., Kaparos, Efiyenia, Whiten, Gabrielle C., Ssebyala, Shakirah et al. · 2020 · Molecular Cell
72. Roles of homologous recombination in response to ionizing radiation-induced DNA damage
    Jac A. Nickoloff, Neelam Sharma, Chris Allen, Lynn E. Taylor, Sage J. Allen, Aruna Shanker Jaiswal, Robert Hromas · 2021 · International Journal of Radiation Biology
73. Transcription–replication conflicts in primordial germ cells necessitate the Fanconi anemia pathway to safeguard genome stability
    Yajuan Yang, Weiwei Xu, Fei Gao, Canxin Wen, Simin Zhao, Yongze Yu, Wenlin Jiao, Xin Mi, Yingying Qin, Zi‐Jiang Chen et al. · 2022 · Proceedings of the National Academy of Sciences
74. The Emerging Role of miR-223 in Platelet Reactivity: Implications in Antiplatelet Therapy
    Rui Shi, Xin Zhou, Wenjie Ji, Yingying Zhang, Yongqiang Ma, Jian-Qi Zhang, Yuming Li · 2015 · BioMed Research International
75. Non-catalytic Roles for XPG with BRCA1 and BRCA2 in Homologous Recombination and Genome Stability
    Kelly S. Trego, Torsten Groesser, Albert R. Davalos, Ann Christin Parplys, Weixing Zhao, Michael R. Nelson, Aye Su Hlaing, Brian Shih, Björn Rydberg, Janice M. Pluth et al. · 2016 · Molecular Cell
76. How Human Papillomavirus Replication and Immune Evasion Strategies Take Advantage of the Host DNA Damage Repair Machinery
    Valentina Bordignon, Enea Gino Di Domenico, Elisabetta Trento, Giovanna D’Agosto, Ilaria Cavallo, Martina Pontone, Fulvia Pimpinelli, Luciano Mariani, Fabrizio Ensoli · 2017 · Viruses
77. Chromatin remodeler HELLS maintains glioma stem cells through E2F3 and MYC
    Guoxin Zhang, Zhen Dong, Briana C. Prager, Leo J.Y. Kim, Qiulian Wu, Ryan C. Gimple, Xiuxing Wang, Shideng Bao, Petra Hamerlik, Jeremy N. Rich · 2019 · JCI Insight
78. CHK1 Inhibitor Blocks Phosphorylation of FAM122A and Promotes Replication Stress
    Feng Li, David Kozono, Peter V. Deraska, Timothy B. Branigan, Connor E. Dunn, Xiao-Feng Zheng, Kalindi Parmar, Huy Q. Nguyen, James A. DeCaprio, Geoffrey Ira Shapiro et al. · 2020 · Molecular Cell
79. Homology-directed repair protects the replicating genome from metabolic assaults
    Kumar Somyajit, Julian Spies, Fabian Coscia, Ufuk Kirik, Maj‐Britt Rask, Ji‐Hoon Lee, Kai J. Neelsen, Andreas Mund, Lars Juhl Jensen, Tanya T. Paull et al. · 2021 · Developmental Cell
80. Cyclin E expression is associated with high levels of replication stress in triple-negative breast cancer
    Sergi Guerrero Llobet, Bert van der Vegt, Evelien Jongeneel, Rico D. Bense, Mieke C. Zwager, Carolien P. Schröder, Marieke Everts, Rudolf S.N. Fehrmann, Geertruida H. de Bock, Marcel A.T.M. van Vugt · 2020 · npj Breast Cancer
81. MIF is a 3’ flap nuclease that facilitates DNA replication and promotes tumor growth
    Yijie Wang, Yan Chen, Mingming Yang, Yanan Wang, Yanan Wang, Lei Bao, Jennifer E. Wang, BongWoo Kim, Kara Y. Chan, Weizhi Xu et al. · 2021 · Nature Communications
82. TRIM21 suppresses CHK1 activation by preferentially targeting CLASPIN for K63-linked ubiquitination
    Xuefei Zhu, Jingwei Xue, Xing Yu Jiang, Yamin Gong, Congwen Gao, Ting Cao, Qian Li, Lulu Bai, Yuwei Li, Gaixia Xu et al. · 2022 · Nucleic Acids Research
83. Stalled replication fork protection limits cGAS–STING and P-body-dependent innate immune signalling
    Ahmed Emam, Xiao Y. Wu, Shengfeng Xu, Longqiang Wang, Shichang Liu, Bin Wang · 2022 · Nature Cell Biology
84. First-in-Human Study of the Ataxia Telangiectasia and Rad3-Related (ATR) Inhibitor Tuvusertib (M1774) as Monotherapy in Patients with Solid Tumors
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85. DNA-PK triggers histone ubiquitination and signaling in response to DNA double-strand breaks produced during the repair of transcription-blocking topoisomerase I lesions
    Agnese Cristini, Joon-Hyung Park, Giovanni Capranico, Gaëlle Legube, Gilles Favre, Olivier Sordet · 2015 · Nucleic Acids Research
86. Cyclin E Deregulation and Genomic Instability
    Leonardo K. Teixeira, Steven I. Reed · 2017 · Advances in experimental medicine and biology
87. Spatiotemporal dynamics of homologous recombination repair at single collapsed replication forks
    Donna R. Whelan, Wei Ting C. Lee, Yandong Yin, Dylan M. Ofri, Keria Bermudez‐Hernandez, Sarah Keegan, David Fenyö, Eli Rothenberg · 2018 · Nature Communications
88. SLX4: multitasking to maintain genome stability
    Jean-Hugues Guervilly, Pierre-Henri L. Gaillard · 2018 · Critical Reviews in Biochemistry and Molecular Biology
89. DNA minor groove binding of a well known anti-mycobacterial drug dapsone: A spectroscopic, viscometric and molecular docking study
    Ayon Chakraborty, Alok Kumar Panda, Rajesh Ghosh, Ashis Biswas · 2019 · Archives of Biochemistry and Biophysics
90. CD98hc (SLC3A2) sustains amino acid and nucleotide availability for cell cycle progression
    Sara Cano-Crespo, Josep Chillarón, Alexandra Junza, Gonzalo Fernández‐Miranda, Judit García, Christine Polte, Laura Rodríguez de la Ballina, Zoya Ignatova, Óscar Yanes, Antonio Zorzano A et al. · 2019 · Scientific Reports
91. WAPL-Dependent Repair of Damaged DNA Replication Forks Underlies Oncogene-Induced Loss of Sister Chromatid Cohesion
    Bente Benedict, Janne J. M. van Schie, Anneke B. Oostra, Jesper A. Balk, Rob M.F. Wolthuis, Hein te Riele, Job de Lange · 2020 · Developmental Cell
92. Loss of Cyclin C or CDK8 provides ATR inhibitor resistance by suppressing transcription-associated replication stress
    Rebecca L. Lloyd, Václav Urban, Francisco Muñoz‐Martínez, Iñigo Ayestaran, John Christopher Thomas, Christelle de Renty, Mark J. O’Connor, Josep V. Forment, Yaron Galanty, Stephen P Jackson · 2021 · Nucleic Acids Research
93. Human CDK18 promotes replication stress signaling and genome stability
    Barone, Giancarlo, Staples, Christopher J., Ganesh, Anil, Patterson, Karl W., Bryne, Dominic P., Myers, Katie N., Patil, Abhijit A., Eyers, Claire E., Maslen, Sarah, Skehel, J. Mark et al. · 2016 · Nucleic Acids Research
94. Chromatin Replication and Histone Dynamics
    Constance Alabert, Zuzana Jasencakova, Anja Groth · 2017 · Advances in experimental medicine and biology
95. RAD51 protects human cells from transcription-replication conflicts
    Rahul Bhowmick, Mads Lerdrup, Sampath Amitash Gadi, Giacomo G. Rossetti, Manika Indrajit Singh, Ying Liu, Thanos D. Halazonetis, Ian D. Hickson · 2022 · Molecular Cell
96. The emerging roles of TRIM21 in coordinating cancer metabolism, immunity and cancer treatment
    Xintian Chen, Menghan Cao, Pengfei Wang, Sufang Chu, Minle Li, Pingfu Hou, Junnian Zheng, Zhongwei Li, Jin Bai · 2022 · Frontiers in Immunology
97. Endogenous DNA Double-Strand Breaks during DNA Transactions: Emerging Insights and Methods for Genome-Wide Profiling
    Britta A. M. Bouwman, Nicola Crosetto · 2018 · Genes
98. Replication stress induces mitotic death through parallel pathways regulated by WAPL and telomere deprotection
    V. Pragathi Masamsetti, Ronnie Ren Jie Low, Ka Sin Mak, Aisling O’Connor, Chris D. Riffkin, Noa Lamm, Laure Crabbé, Jan Karlseder, David C.S. Huang, Makoto Hayashi et al. · 2019 · Nature Communications
99. Working on Genomic Stability: From the S-Phase to Mitosis
    Sara Ovejero, Avelino Bueno, María P. Sacristán · 2020 · Genes
100. Removal of RTF2 from Stalled Replisomes Promotes Maintenance of Genome Integrity
     Kottemann, Molly C., Conti, Brooke A., Lach, Francis P., Smogorzewska, Agata · 2018 · Molecular Cell