Causes and consequences of replication stress

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Items 601–700 of 1,001

1. A Small-Molecule Inhibitor of Human DNA Polymerase η Potentiates the Effects of Cisplatin in Tumor Cells
   Maroof Khan Zafar, Leena Maddukuri, Amit D. Ketkar, Narsimha Reddy Penthala, Megan R. Reed, Sarah Eddy, Peter Anthony Crooks, Robert Lawton Eoff · 2018 · Biochemistry
2. Sublethal engagement of apoptotic pathways in residual cancer
   Shane T. Killarney, Stephen W. G. Tait, Douglas R. Green, Kris C. Wood · 2023 · Trends in Cell Biology
3. Alternative lengthening of telomeres: mechanism and the pathogenesis of cancer
   Joakin Mori, Joshua Keegan, Rachel Litman Flynn, Christopher M. Heaphy · 2023 · Journal of Clinical Pathology
4. Latexin sensitizes leukemogenic cells to gamma-irradiation-induced cell-cycle arrest and cell death through Rps3 pathway
   Yanwu You, R Wen, Rupak Pathak, A Li, Wei-Hua Li, Daret K. St. Clair, Martin Hauer‐Jensen, Daohong Zhou, Y Liang · 2014 · Cell Death and Disease
5. Identification of Multiple Proteins Coupling Transcriptional Gene Silencing to Genome Stability in Arabidopsis thaliana
   Christopher J. Hale, Magdalena E. Potok, Jennifer C. Lopez, Truman J. Do, Ao Liu, Javier Gallego‐Bartolomé, Scott D. Michaels, Steven E. Jacobsen · 2016 · PLoS Genetics
6. Around and beyond 53BP1 Nuclear Bodies
   Anne Fernandez-Vidal, Julien Vignard, Gladys Mirey · 2017 · International Journal of Molecular Sciences
7. MOF Suppresses Replication Stress and Contributes to Resolution of Stalled Replication Forks
   Dharmendra Kumar Singh, RAJ KUMAR PANDITA, Mayank Kumar Singh, Sharmistha Chakraborty, Shashank Hambarde, Deepti B. Ramnarain, Vijaya Charaka, Kazi Mokim Ahmed, Clayton R. Hunt, Tej K. Pandita · 2018 · Molecular and Cellular Biology
8. HMCES safeguards replication from oxidative stress and ensures error‐free repair
   Mrinal Srivastava, Dan Su, Huimin Zhang, Zhen Chen, Mengfan Tang, Litong Nie, Junjie Chen · 2020 · EMBO Reports
9. SLFN11 promotes stalled fork degradation that underlies the phenotype in Fanconi anemia cells
   Yusuke Okamoto, Masako Abe, Anfeng Mu, Yasuko Tempaku, Colette B. Rogers, Ayako L. Mochizuki, Yoko Katsuki, Masato T. Kanemaki, Akifumi Takaori‐Kondo, Alexandra Sobeck et al. · 2020 · Blood
10. The S-phase-induced lncRNA SUNO1 promotes cell proliferation by controlling YAP1/Hippo signaling pathway
    Qinyu Hao, Xinying Zong, Qinyu Sun, Yo-Chuen Lin, You Jin Song, Seyedsasan Hashemikhabir, Rosaline Y.C. Hsu, Mohammad Zahid Kamran, Ritu Chaudhary, Vidisha Tripathi et al. · 2020 · eLife
11. Lethal and Non-Lethal Functions of Caspases in the DNA Damage Response
    Karla E. Lopez, Lisa Bouchier‐Hayes · 2022 · Cells
12. Stress-triggered hematopoietic stem cell proliferation relies on PrimPol-mediated repriming
    Kurt Jacobs, Cyril Doerdelmann, Jana Krietsch, Daniel González‐Acosta, Nicolas Mathis, Saul Kushinsky, Estrella Guarino, Carmen Gómez‐Escolar, Dolores Martínez, Jonas Andreas Schmid et al. · 2022 · Molecular Cell
13. Antitumor Effects of a Novel Small Molecule Targeting PCNA Chromatin Association in Prostate Cancer
    Kelsey Dillehay McKillip, Shan Lu, Zhongyun Dong · 2014 · Molecular Cancer Therapeutics
14. SPOP mutation induces replication over-firing by impairing Geminin ubiquitination and triggers replication catastrophe upon ATR inhibition
    Jian Ma, Qing Shi, Gaofeng Cui, Haoyue Sheng, Maria Victoria Botuyan, Yingke Zhou, Yuqian Yan, Yundong He, Liguo Wang, Yuzhuo Z. Wang et al. · 2021 · Nature Communications
15. CDT1 inhibits CMG helicase in early S phase to separate origin licensing from DNA synthesis
    Nalin Ratnayeke, Yasemin Baris, Mingyu Chung, Joseph T.P. Yeeles, Tobias Meyer · 2023 · Molecular Cell
16. HLTF resolves G4s and promotes G4-induced replication fork slowing to maintain genome stability
    Gongshi Bai, Theresa Endres, Ulrike Kühbacher, Valentina Mengoli, Briana H. Greer, Emma M. Peacock, Matthew D. Newton, Tyler H. Stanage, Maria Rosaria Dello Stritto, Roxana Lungu et al. · 2024 · Molecular Cell
17. Bim directly antagonizes Bcl-xl in doxorubicin-induced prostate cancer cell apoptosis independently of p53
    Min-Chi Yang, Ru‐Wei Lin, Shih‐Bo Huang, Shin-Yuan Huang, Wenjie Chen, Shiaw Wang, Yi‐Ren Hong, Chihuei Wang · 2015 · Cell Cycle
18. Activity and in vivo dynamics of Bacillus subtilis DisA are affected by RadA/Sms and by Holliday junction-processing proteins
    Carolina Gándara, Daniella Lucena, Rubén Torres, Ester Serrano, Stephan Altenburger, Peter L. Graumann, Juan C. Alonso · 2017 · DNA repair
19. Oncogene-Induced Replication Stress Drives Genome Instability and Tumorigenesis
    Dan Sarni, Batsheva Kerem · 2017 · International Journal of Molecular Sciences
20. Epigenetic changes in the early stage of silica-induced cell transformation
    Carole Seidel, Anaïs Kirsch, Caroline Fontana, Athanase Visvikis, Aurélie Remy, Laurent Gaté, Christian Darné, Yves Guichard · 2017 · Nanotoxicology
21. Loss of NEIL3 DNA glycosylase markedly increases replication associated double strand breaks and enhances sensitivity to ATR inhibitor in glioblastoma cells
    Alex W. Klattenhoff, Megha A. Thakur, Christopher S. Chu, Debolina Ray, Samy L. Habib, Dawit Kidane · 2017 · Oncotarget
22. Torin2 Exploits Replication and Checkpoint Vulnerabilities to Cause Death of PI3K-Activated Triple-Negative Breast Cancer Cells
    Sameer S. Chopra, Anne Jenney, Adam Christopher Palmer, Mario Niepel, Mirra Chung, Caitlin E. Mills, Sindhu Carmen Sivakumaren, Qingsong Liu, Jia-Yun Chen, Clarence Yapp et al. · 2019 · Cell Systems
23. DNA–protein crosslinks from environmental exposure: Mechanisms of formation and repair
    Yusuke Kojima, Yuichi Machida · 2020 · Environmental and Molecular Mutagenesis
24. MCM10 compensates for Myc‐induced DNA replication stress in breast cancer stem‐like cells
    Takahiko Murayama, Yasuto Takeuchi, Kaoru Yamawaki, Toyoaki Natsume, Mengjiao Li, Rojas‐Chaverra N. Marcela, Tatsunori Nishimura, Yuta Kogure, Asuka Nakata, Kana Tominaga et al. · 2020 · Cancer Science
25. CST in maintaining genome stability: beyond telomeres
    Xinxing Lyu, Pau Biak Sang, Wei-Hang Chai · 2021 · DNA Repair
26. A Tale of Ice and Fire: The Dual Role for 17β-Estradiol in Balancing DNA Damage and Genome Integrity
    Sara Pescatori, Francesco Berardinelli, Jacopo Albanesi, Paolo Ascenzi, Maria Marino, Antonio Antoccia, Alessandra di Masi, Filippo Acconcia · 2021 · Cancers
27. Large-scale preparation of fluorescence multiplex host cell reactivation (FM-HCR) reporters
    Cortt G. Piett, Turner J. Pecen, Daniel J. Laverty, Zachary David Nagel · 2021 · Nature Protocols
28. Mechanisms and Regulation of DNA-Protein Crosslink Repair During DNA Replication by SPRTN Protease
    Megan C. Perry, Gargi Ghosal · 2022 · Frontiers in Molecular Biosciences
29. Personalised pathway analysis reveals association between DNA repair pathway dysregulation and chromosomal instability in sporadic breast cancer
    Chao Liu, Sriganesh Srihari, Samir Lal, Benoît Gautier, Peter T. Simpson, Kum Kum Khanna, Mark A. Ragan, Kim‐Anh Lê Cao · 2015 · Molecular Oncology
30. Cohesin maintains replication timing to suppress DNA damage on cancer genes
    Jinchun Wu, Yang Liu, Zhengrong Zhangding, Xuhao Liu, Ai Chen, Tingting Gan, Haoxin Liang, Yuefeng Guo, Mohan Chen, Yiyang Liu et al. · 2023 · Nature Genetics
31. Cancer Mutations Converge on a Collection of Protein Assemblies to Predict Resistance to Replication Stress
    Xiaoyu Zhao, Akshat Singhal, Sungjoon Park, JungHo Kong, Robin E. Bachelder, Trey E. Ideker · 2024 · Cancer Discovery
32. AKT1 interacts with DHX9 to Mitigate R Loop–Induced Replication Stress in Ovarian Cancer
    Tzu‐Ting Huang, Chih-Yuan Chiang, Jayakumar R. Nair, Kelli M. Wilson, Ken Chih-Chien Cheng, Jung‐Min Lee · 2024 · Cancer Research
33. Recent advances in graphene oxide-based electrochemical sensors
    Carlos A. Ramirez, Antony Raj Thiruppathi, Okoroike C. Ozoemena, Aicheng Chen · 2024 · Canadian Journal of Chemistry
34. Targeting Protein Kinase, Membrane-Associated Tyrosine/Threonine 1 (PKMYT1) for Precision Cancer Therapy: From Discovery to Clinical Trial
    Ming Yang, Hua Xiang, Guoshun Luo · 2024 · Journal of Medicinal Chemistry
35. Enhancer of Rudimentary Homolog Affects the Replication Stress Response through Regulation of RNA Processing
    Gina M. Kavanaugh, Runxiang Zhao, Yan Ping Guo, Kareem N. Mohni, Gloria G. Glick, Monica E. Lacy, M. Shane Hutson, Manuel Ascano, David Cortez · 2015 · Molecular and Cellular Biology
36. Rad51 recruitment and exclusion of non-homologous end joining during homologous recombination at a Tus/Ter mammalian replication fork barrier
    Nicholas A. Willis, Arvind Panday, Erin E. Duffey, Ralph Scully · 2018 · PLoS Genetics
37. DNA Damage Response Inhibitor Combinations Exert Synergistic Antitumor Activity in Aggressive B-Cell Lymphomas
    Valentina Restelli, Monica Lupi, Rosaria Chilà, Micaela Vagni, Chiara Tarantelli, Filippo Spriano, Eugenio Gaudio, Francesco Bertoni, Giovanna L.M. Damia, Laura Carrassa · 2019 · Molecular Cancer Therapeutics
38. SMC5/6 is required for replication fork stability and faithful chromosome segregation during neurogenesis
    Alisa Atkins, Michelle J. Xu, Maggie Li, Nathaniel P. Rogers, Marina V. Pryzhkova, Philip W. Jordan · 2020 · eLife
39. Reprogramming of nucleotide metabolism by interferon confers dependence on the replication stress response pathway in pancreatic cancer cells
    Evan R. Abt, Thuc M. Le, Amanda M. Dann, Joseph R. Capri, Soumya Poddar, Vincent M. Lok, Luyi Li, Keke Liang, Amanda L. Creech, Khalid Rashid et al. · 2022 · Cell Reports
40. The "enemies within": regions of the genome that are inherently difficult to replicate
    Rahul Bhowmick, Ian David Hickson · 2017 · F1000Research
41. Pold3is required for genomic stability and telomere integrity in embryonic stem cells and meiosis
    Zhongcheng Zhou, Lingling Wang, Feixiang Ge, Peng Gong, Hua Wang, Feng Wang, Lingyi Chen, Lin Liu · 2018 · Nucleic Acids Research
42. Role of histone acetyltransferases MOF and Tip60 in genome stability
    Mir, Ulfat Syed, Bhat, Audesh, Mushtaq, Arjamand, Pandita, Shruti, Altaf, Mohammad, Pandita, Tej K. · 2021 · DNA repair
43. Inhibition of uracil DNA glycosylase sensitizes cancer cells to 5-fluorodeoxyuridine through replication fork collapse-induced DNA damage
    Yan Yan, Xiangzi Han, Yulan Qing, Allison G. Condie, Shashank Gorityala, Shuming Yang, Yan Xu, Youwei Zhang, Stanton L. Gerson · 2016 · Oncotarget
44. DNA replication stress triggers rapid DNA replication fork breakage by Artemis and XPF
    Rémy Betous, Théo Goullet de Rugy, Alessandra Luíza Pelegrini, Sophie Queillé, Jean‐Pierre de Villartay, Jean‐Sébastien Hoffmann · 2018 · PLoS Genetics
45. Smarcal1 and Zranb3 Protect Replication Forks from Myc-Induced DNA Replication Stress
    Matthew V. Puccetti, Clare M. Adams, Saul Kushinsky, Christine M. Eischen · 2019 · Cancer Research
46. WRNIP1 Protects Reversed DNA Replication Forks from SLX4-Dependent Nucleolytic Cleavage
    Bartłomiej Porębski, Sebastian Wild, Sandra Kummer, Sarah Scaglione, Pierre-Henri L. Gaillard, Kerstin Gari · 2019 · iScience
47. MCL1 Is Required for Maintenance of Intestinal Homeostasis and Prevention of Carcinogenesis in Mice
    Marc Eammonn Healy, Yannick Boege, Michael C. Hodder, Friederike Böhm, Mohsen Malehmir, Anna‐Lena Scherr, Jasna Jetzer, Lap Kwan Chan, Rossella Parrotta, Kurt Jacobs et al. · 2020 · Gastroenterology
48. Genomic Instability in Fungal Plant Pathogens
    Shay Covo · 2020 · Genes
49. Histone chaperone FACT is essential to overcome replication stress in mammalian cells
    Laura A. Prendergast, Erin Hong, Alfiya F. Safina, Dante Poe, Katerina V. Gurova · 2020 · Oncogene
50. Under-Replicated DNA: The Byproduct of Large Genomes?
    Agustina P. Bertolin, Jean‐Sébastien Hoffmann, Vanesa Gottifredi · 2020 · Cancers
51. Dual targeting of higher-order DNA structures by azacryptands induces DNA junction-mediated DNA damage in cancer cells
    Joanna Zell, Katerina Duskova, Leïla Chouh, Madeleine Bossaert, Nicolas Chéron, Anton Granzhan, Sébastien Britton, David Monchaud · 2021 · Nucleic Acids Research
52. MCMBP promotes the assembly of the MCM2–7 hetero-hexamer to ensure robust DNA replication in human cells
    Yuichiro Saito, Venny Santosa, Kei-ichiro Ishiguro, Masato T. Kanemaki · 2022 · eLife
53. WASp modulates RPA function on single-stranded DNA in response to replication stress and DNA damage
    Seong‐Su Han, Kuo‐Kuang Wen, Maria Luisa García-Rubio, Marc S. Wold, Andrés Aguilera, Wojciech Niedźwiedź, Yatin M. Vyas · 2022 · Nature Communications
54. Genomic instability: Crossing pathways at the origin of structural and numerical chromosome changes
    Antonella Russo, Francesca Pacchierotti, Daniela Cimini, Neil J. Ganem, Anna Genescà, A.T. Natarajan, Sofia Pavanello, Giorgio Valle, Francesca Degrassi · 2015 · Environmental and Molecular Mutagenesis
55. Deterministic effect of oxygen level variation on shaping antibiotic resistome
    Sakina Bombaywala, Abhay Bajaj, Nishant A. Dafale · 2023 · Journal of Hazardous Materials
56. Antimicrobial Activity and Mechanisms of Walnut Green Husk Extract
    Lei Wang, Wenjing Li, Xuanyue Li, Jiancheng Liu, Yong Chen · 2023 · Molecules
57. Nuclear actin dynamics and functions at a glance
    Svenja Ulferts, Massimo Lopes, Kei Miyamoto, Robert Grosse · 2024 · Journal of Cell Science
58. Heterochromatin Controls γH2A Localization in Neurospora crassa
    Takahiko Sasaki, Kelsey L. Lynch, Caitlin V. Mueller, Steven Friedman, Michael Freitag, Zachary Lewis · 2014 · Eukaryotic Cell
59. Inhibiting PI3Kβ with AZD8186 Regulates Key Metabolic Pathways in PTEN-Null Tumors
    James T. Lynch, Urszula M. Polanska, Oona Delpuech, Urs J. Hancox, Antonio G. Trinidad, Filippos Michopoulos, Carol Lenaghan, Robert K. McEwen, James R. Bradford, Radek Polanski et al. · 2017 · Clinical Cancer Research
60. Evaluation of mechanisms that may generate DNA lesions triggering antigenic variation in African trypanosomes
    Marcelo S. da Silva, Galadriel A. Hovel-Miner, Emma M. Briggs, Maria Carolina Elias, Richard McCulloch · 2018 · PLoS Pathogens
61. A distinct role for recombination repair factors in an early cellular response to transcription–replication conflicts
    Xin Shao, Amalie M Joergensen, Niall G. Howlett, Michael Lisby, Vibe H. Oestergaard · 2020 · Nucleic Acids Research
62. Shelterin and the replisome: at the intersection of telomere repair and replication
    Alessandro Cicconi, Sandy S. Chang · 2020 · Current Opinion in Genetics & Development
63. Mechanisms of direct replication restart at stressed replisomes
    Brooke A. Conti, Agata Smogorzewska · 2020 · DNA repair
64. Roles of ATM and ATR in DNA double strand breaks and replication stress
    Rhys M. Williams, Xiaodong Zhang · 2021 · Progress in Biophysics and Molecular Biology
65. Replication Stress, Genomic Instability, and Replication Timing: A Complex Relationship
    Lina-Marie Briu, Chrystelle Antoinat Maric, Jean‐Charles Cadoret · 2021 · International Journal of Molecular Sciences
66. The plant DNA polymerase theta is essential for the repair of replication‐associated DNA damage
    Maherun Nisa, Clara Bergis, José Antonio Pedroza Garcia, Jeannine Drouin‐Wahbi, Christelle Mazubert, Catherine Bergounioux A, Moussa Benhamed, Cécile Raynaud · 2021 · The Plant Journal
67. The intra-S phase checkpoint directly regulates replication elongation to preserve the integrity of stalled replisomes
    Yang Liu, Lu Wang, Xin Xu, Yue Yuan, Bo Zhang, Zeyang Li, Yuchen Xie, Rui Yan, Zeqi Zheng, Jianguo Ji et al. · 2021 · Proceedings of the National Academy of Sciences
68. Oxidative Stress and DNA Damage at Telomeres
    Opresko, Patricia L., Sanford, Samantha L., De Rosa, Mariarosaria · 2025 · Cold Spring Harbor Perspectives in Biology
69. MAD2L2 promotes replication fork protection and recovery in a shieldin-independent and REV3L-dependent manner
    Inés Paniagua, Zainab Tayeh, Mattia Falcone, Santiago Hernández-Pérez, Aurora Cerutti, Jacqueline J.L. Jacobs · 2022 · Nature Communications
70. PRMT blockade induces defective DNA replication stress response and synergizes with PARP inhibition
    Yang Li, Lacey Elizabeth Dobrolecki, Christina Sallas, Xudong Zhang, Travis D. Kerr, Deepa Bisht, Yalong Wang, Sharad Awasthi, Babita Kaundal, Siqi Wu et al. · 2023 · Cell Reports Medicine
71. Heme oxygenase-1 protects cells from replication stress
    Patryk Chudy, Jakub A. Kochan, Mateusz Wawro, Phu Nguyen, Monika E. Gorczyca, Aliaksandra Varanko, Aleksandra Retka, Swati Sweta Ghadei, Emilija Napieralska, Anna Grochot‐Przeczek et al. · 2024 · Redox Biology
72. Managing Single-Stranded DNA during Replication Stress in Fission Yeast
    Sarah Sabatinos, Susan L. Forsburg · 2015 · Biomolecules
73. Inhibition of checkpoint kinase 1 following gemcitabine-mediated S phase arrest results in CDC7- and CDK2-dependent replication catastrophe
    Nicholas J.H. Warren, Alan R. Eastman · 2018 · Journal of Biological Chemistry
74. Visualizing locus-specific sister chromatid exchange reveals differential patterns of replication stress-induced fragile site breakage
    Irina S.-R. Waisertreiger, Katherine Popovich, Maya Block, Krista R. Anderson, Jacqueline H. Barlow · 2019 · Oncogene
75. Exploiting Replication Stress as a Novel Therapeutic Intervention
    Jeffrey C. Martin, Tamara J. Hoegel, Miranda L. Lynch, Anna Woloszynska‐Read, Thomas Melendy, Joyce Ellen Ohm · 2020 · Molecular Cancer Research
76. Control of replication stress and mitosis in colorectal cancer stem cells through the interplay of PARP1, MRE11 and RAD51
    Gwenola Manic, Martina Musella, Francesca Corradi, Antonella Sistigu, Sara Vitale, Sara Soliman Abdel Rehim, Luca Mattiello, Eva Malacaria, Claudia Galassi, Michele Signore et al. · 2021 · Cell Death and Differentiation
77. A phase 1b study evaluating the safety and preliminary efficacy of berzosertib in combination with gemcitabine in patients with advanced non-small cell lung cancer
    Ruth Plummer, Emma Jane Dean, Hendrik‐Tobias Arkenau, Charles H. Redfern, Alexander I. Spira, Jason M. Melear, Ki Young Chung, Jordi Ferrer-Playan, Thomas Goddemeier, Giuseppe Locatelli et al. · 2021 · Lung Cancer
78. A positive feedback loop: RAD18-YAP-TGF-β between triple-negative breast cancer and macrophages regulates cancer stemness and progression
    Xueqi Yan, Yaozhou He, Shikun Yang, Tianyu Zeng, Yijia Hua, Shengnan Bao, Fan Yang, Ningjun Duan, Chunxiao Sun, Yan Liang et al. · 2022 · Cell Death Discovery
79. Transcription-associated events affecting genomic integrity
    Robin Sebastian, Philipp Oberdoerffer · 2017 · Philosophical Transactions of the Royal Society B Biological Sciences
80. TUG1-mediated R-loop resolution at microsatellite loci as a prerequisite for cancer cell proliferation
    Miho M. Suzuki, Kenta Iijima, Koichi Ogami, Keiko Shinjo, Yoshiteru Murofushi, Jingqi Xie, Xuebing Wang, Yotaro Kitano, A. Mamiya, Yuji Kibe et al. · 2023 · Nature Communications
81. USP1-dependent nucleolytic expansion of PRIMPOL-generated nascent DNA strand discontinuities during replication stress
    Alexandra Nusawardhana, Lindsey M Pale, Claudia M. Nicolae, George‐Lucian Moldovan · 2024 · Nucleic Acids Research
82. Bacillus subtilis DisA helps to circumvent replicative stress during spore revival
    Marina Raguse, Rubén Torres, Elena M. Seco, Carolina Gándara, Silvia Ayora, Ralf Moeller, Juan C. Alonso · 2017 · DNA repair
83. Detours to Replication: Functions of Specialized DNA Polymerases during Oncogene-induced Replication Stress
    Wei-Chung Tsao, Kristin A. Eckert · 2018 · International Journal of Molecular Sciences
84. The Nup84 complex coordinates the DNA damage response to warrant genome integrity
    Hélène Gaillard, José M. Santos-Pereira, Andrés Aguilera · 2019 · Nucleic Acids Research
85. EXD2 Protects Stressed Replication Forks and Is Required for Cell Viability in the Absence of BRCA1/2
    Jadwiga Nieminuszczy, Ronan Broderick, Marina A. Bellani, Elizabeth A. Smethurst, Rebekka A. Schwab, Veronica Cherdyntseva, Theodora Evmorfopoulou, Yi‐Ching Lin, Michal A. Minczuk, Philippe Pasero et al. · 2019 · Molecular Cell
86. Genome-wide mapping and profiling of γH2AX binding hotspots in response to different replication stress inducers
    Xinxing Lyu, Megan Chastain, Weihang Chai · 2019 · BMC Genomics
87. MiR223-3p promotes synthetic lethality in BRCA1-deficient cancers
    Srinivasan, Gayathri, Williamson, Elizabeth A., Kong, Kimi, Jaiswal, Aruna S., Huang, Guangcun, Kim, Hyun-Suk, Schärer, Orlando, Zhao, Weixing, Burma, Sandeep, Sung, Patrick et al. · 2019 · Proceedings of the National Academy of Sciences
88. Functional Genomic Screen in Mesothelioma Reveals that Loss of Function of BRCA1-Associated Protein 1 Induces Chemoresistance to Ribonucleotide Reductase Inhibition
    Agata Okonska, Saskja Bühler, Vasundhara Rao, Manuel Ronner, Maxime Blijlevens, Ida H. van der Meulen‐Muileman, Renée X. de Menezes, Martin Wipplinger, Kathrin Oehl, Egbert Frederik Smit et al. · 2019 · Molecular Cancer Therapeutics
89. Established and Novel Mechanisms Leading to de novo Genomic Rearrangements in the Human Germline
    Atsushi Hattori, Maki Fukami · 2020 · Cytogenetic and Genome Research
90. A CDC7 inhibitor sensitizes DNA-damaging chemotherapies by suppressing homologous recombination repair to delay DNA damage recovery
    Kenichi Iwai, Tadahiro Nambu, Yukie Kashima, Jie Yu, Kurt Eng, Kazumasa Miyamoto, Kazuyo Kakoi, Masamitsu Gotou, Toshiyuki Takeuchi, Akifumi Kogame et al. · 2021 · Science Advances
91. The Safe Path at the Fork: Ensuring Replication-Associated DNA Double-Strand Breaks are Repaired by Homologous Recombination
    Jac A. Nickoloff, Neelam Sharma, Lynn E. Taylor, Sage J. Allen, Robert Hromas · 2021 · Frontiers in Genetics
92. Life of double minutes: generation, maintenance, and elimination
    Mila Ilić, Irene C. Zaalberg, Jonne A. Raaijmakers, René H. Medema · 2022 · Chromosoma
93. Investigating the Anticancer Potential of Salvicine as a Modulator of Topoisomerase II and ROS Signaling Cascade
    Dipta Dey, Mohammad Mehedi Hasan, Partha Biswas, Stavros P. Papadakos, Rehab Α. Rayan, Sabiha Tasnim, Muhammad Bilal, Mohammod Johirul Islam, Farzana Alam Arshe, Efat Muhammad Arshad et al. · 2022 · Frontiers in Oncology
94. The genome of a hadal sea cucumber reveals novel adaptive strategies to deep-sea environments
    Guangming Shao, Tianliang He, Yinnan Mu, Pengfei Mu, Jingqun Ao, Xihuang Lin, Lingwei Ruan, YuGuang Wang, Yuan Gao, Dinggao Liu et al. · 2022 · iScience
95. DNA Damage Response Mechanisms in Head and Neck Cancer: Significant Implications for Therapy and Survival
    Chara Papalouka, Maria Adamaki, Panagiota Batsaki, Panagiotis Zoumpourlis, Antonis Tsintarakis, Maria Goulielmaki, Sotirios P. Fortis, Constantin N. Baxevanis, Vassilis C. Zoumpourlis · 2023 · International Journal of Molecular Sciences
96. Disentangling the roles of aneuploidy, chromosomal instability and tumour heterogeneity in developing resistance to cancer therapies
    Joana Andrade, A. Gallagher, Jovanna Maharaj, Sarah Elizabeth McClelland · 2023 · Chromosome Research
97. Therapeutic targeting of ATR in alveolar rhabdomyosarcoma
    Heathcliff Dorado García, Fabian F. Pusch, Yi Bei, Jennifer von Stebut, Glorymar Ibáñez, Kristina C. Guillan, Koshi Imami, Dennis Gürgen, Jana Rolff, Konstantin Helmsauer et al. · 2022 · Nature Communications
98. Alternative lengthening of telomeres (ALT) cells viability is dependent on C-rich telomeric RNAs
    Ilaria Rosso, Corey Winston Jones-Weinert, Francesca Rossiello, Matteo Cabrini, Silvia Brambillasca, Leonel Muñoz‐Sagredo, Zeno Lavagnino, Emanuele Martini, Enzo Tedone, Massimiliano Garrè et al. · 2023 · Nature Communications
99. MCM8 interacts with DDX5 to promote R-loop resolution
    Canxin Wen, Lili Cao, Shuhan Wang, Weiwei Xu, Yongze Yu, Simin Zhao, Fan Yang, Zi‐Jiang Chen, Shidou Zhao, Yajuan Yang et al. · 2024 · The EMBO Journal
100. Glucose limitation protects cancer cells from apoptosis induced by pyrimidine restriction and replication inhibition
     Minwoo Nam, Wenxin Xia, Hannan Mir, Alexandra E. Jerrett, Jessica B. Spinelli, Tony T. Huang, Richard Possemato · 2024 · Nature Metabolism