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Autophagosome–lysosome fusion triggers a lysosomal response mediated by TLR9 and controlled by OCRL

De Leo, Maria Giovanna, Staiano, Leopoldo, Vicinanza, Mariella, Luciani, Alessandro, Carissimo, Annamaria, Mutarelli, Margherita, Di Campli, Antonella, Polishchuk, Elena, Di Tullio, Giuseppe, Morra, Valentina, Levtchenko, Elena, Oltrabella, Francesca, Starborg, Tobias, Santoro, Michele, di Bernardo, Diego, Devuyst, Olivier, Lowe, Martin, Medina, Diego L., Ballabio, Andrea, De Matteis, Maria Antonietta·2016·Nature Cell Biology

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  1. Attree, O. et al. The Lowe’s oculocerebrorenal syndrome gene encodes a protein highly homologous to inositol polyphosphate-5-phosphatase. Nature 358, 239–242 (1992). · DOI
  2. Staiano, L., De Leo, M. G., Persico, M. & De Matteis, M. A. Mendelian disorders of PI metabolizing enzymes. Biochim. Biophys. Acta 1851, 867–881 (2015). · DOI
  3. Mehta, Z. B., Pietka, G. & Lowe, M. The cellular and physiological functions of the Lowe syndrome protein OCRL1. Traffic 15, 471–487 (2014). · DOI
  4. Nandez, R. et al. A role of OCRL in clathrin-coated pit dynamics and uncoating revealed by studies of Lowe syndrome cells. Elife 3, e02975 (2014). · DOI
  5. Vicinanza, M. et al. OCRL controls trafficking through early endosomes via PtdIns4,5P(2)-dependent regulation of endosomal actin. EMBO J. 30, 4970–4985 (2011). · DOI · Paper page
  6. Carvalho-Neto, A., Ono, S. E., Cardoso Gde, M., Santos, M. L. & Celidonio, I. Oculocerebrorenal syndrome of Lowe: magnetic resonance imaging findings in the first six years of life. Arq. Neuropsiquiatr. 67, 305–307 (2009). · DOI
  7. Allmendinger, A. M., Desai, N. S., Burke, A. T., Viswanadhan, N. & Prabhu, S. Neuroimaging and renal ultrasound manifestations of Oculocerebrorenal syndrome of Lowe. J. Radiol. Case Rep. 8, 1–7 (2014). · DOI
  8. Oltrabella, F. et al. The Lowe syndrome protein OCRL1 is required for endocytosis in the zebrafish pronephric tubule. PLoS Genet. 11, e1005058 (2015). · DOI
  9. Ramirez, I. B. et al. Impaired neural development in a zebrafish model for Lowe syndrome. Hum. Mol. Genet. 21, 1744–1759 (2012). · DOI
  10. Zhang, X., Hartz, P. A., Philip, E., Racusen, L. C. & Majerus, P. W. Cell lines from kidney proximal tubules of a patient with Lowe syndrome lack OCRL inositol polyphosphate 5-phosphatase and accumulate phosphatidylinositol 4,5-bisphosphate. J. Biol. Chem. 273, 1574–1582 (1998). · DOI
  11. Jiang, P. et al. The HOPS complex mediates autophagosome–lysosome fusion through interaction with syntaxin 17. Mol. Biol. Cell 25, 1327–1337 (2014). · DOI · Paper page
  12. Kochl, R., Hu, X. W., Chan, E. Y. & Tooze, S. A. Microtubules facilitate autophagosome formation and fusion of autophagosomes with endosomes. Traffic 7, 129–145 (2006). · DOI
  13. Itakura, E. & Mizushima, N. Syntaxin 17: the autophagosomal SNARE. Autophagy 9, 917–919 (2013). · DOI
  14. Choudhury, R., Noakes, C. J., McKenzie, E., Kox, C. & Lowe, M. Differential clathrin binding and subcellular localization of OCRL1 splice isoforms. J. Biol. Chem. 284, 9965–9973 (2009). · DOI
  15. Mao, Y. et al. A PH domain within OCRL bridges clathrin-mediated membrane trafficking to phosphoinositide metabolism. EMBO J. 28, 1831–1842 (2009). · DOI
  16. Traub, L. M. et al. AP-2-containing clathrin coats assemble on mature lysosomes. J. Cell Biol. 135, 1801–1814 (1996). · DOI
  17. Rong, Y. et al. Clathrin and phosphatidylinositol-4,5-bisphosphate regulate autophagic lysosome reformation. Nat. Cell Biol. 14, 924–934 (2012). · DOI · Paper page
  18. Sridhar, S. et al. The lipid kinase PI4KIIIβ preserves lysosomal identity. EMBO J. 32, 324–339 (2013). · DOI · Paper page
  19. Mudaliar, H. et al. The role of Toll-like receptor proteins (TLR) 2 and 4 in mediating inflammation in proximal tubules. Am. J. Physiol. Renal Physiol. 305, F143–F154 (2013). · DOI
  20. Benigni, A. et al. Involvement of renal tubular Toll-like receptor 9 in the development of tubulointerstitial injury in systemic lupus. Arthritis Rheumatol. 56, 1569–1578 (2007). · DOI
  21. Li, X. et al. The role of Toll-like receptor (TLR) 2 and 9 in renal ischemia and reperfusion injury. Urology 81, 1379 e15-20 (2013).
  22. Brencicova, E. & Diebold, S. S. Nucleic acids and endosomal pattern recognition: how to tell friend from foe? Front. Cell Infect. Microbiol. 3, 37 (2013). · DOI
  23. Lee, B. L. et al. UNC93B1 mediates differential trafficking of endosomal TLRs. Elife 2, e00291 (2013). · DOI · Paper page
  24. Wu, J. Y. & Kuo, C. C. ADP-ribosylation factor 3 mediates cytidine-phosphate-guanosine oligodeoxynucleotide-induced responses by regulating toll-like receptor 9 trafficking. J. Innate Immun. 7, 623–636 (2015). · DOI
  25. Carchman, E. H. et al. Experimental sepsis-induced mitochondrial biogenesis is dependent on autophagy, TLR4, and TLR9 signaling in liver. FASEB J. 27, 4703–4711 (2013). · DOI
  26. Pawaria, S. et al. Cutting edge: DNase II deficiency prevents activation of autoreactive B cells by double-stranded DNA endogenous ligands. J. Immunol. 194, 1403–1407 (2015). · DOI
  27. Chen, G. et al. A regulatory signaling loop comprising the PGAM5 phosphatase and CK2 controls receptor-mediated mitophagy. Mol. Cell 54, 362–377 (2014). · DOI
  28. Ding, W. X. et al. Nix is critical to two distinct phases of mitophagy, reactive oxygen species-mediated autophagy induction and Parkin-ubiquitin-p62-mediated mitochondrial priming. J. Biol. Chem. 285, 27879–27890 (2010). · DOI · Paper page
  29. Nguyen, T. T. et al. Phosphatidylinositol 4-phosphate 5-kinase α facilitates Toll-like receptor 4-mediated microglial inflammation through regulation of the Toll/interleukin-1 receptor domain-containing adaptor protein (TIRAP) location. J. Biol. Chem. 288, 5645–5659 (2013). · DOI
  30. Platt, N. et al. Immune dysfunction in Niemann-Pick disease type C. J. Neurochem. 136, 74–80 (2015). · DOI
  31. Pirruccello, M. et al. Identification of inhibitors of inositol 5-phosphatases through multiple screening strategies. ACS Chem. Biol. 9, 1359–1368 (2014). · DOI
  32. Zhang, X., Li, X. & Xu, H. Phosphoinositide isoforms determine compartment-specific ion channel activity. Proc. Natl Acad. Sci. USA 109, 11384–11389 (2012). · DOI
  33. Vergarajauregui, S., Connelly, P. S., Daniels, M. P. & Puertollano, R. Autophagic dysfunction in mucolipidosis type IV patients. Hum. Mol. Genet. 17, 2723–2737 (2008). · DOI
  34. Abe, K. & Puertollano, R. Role of TRP channels in the regulation of the endosomal pathway. Physiology (Bethesda) 26, 14–22 (2011).
  35. Grimm, C. et al. Small molecule activators of TRPML3. Chem. Biol. 17, 135–148 (2010). · DOI
  36. Xu, H. & Ren, D. Lysosomal physiology. Annu. Rev. Physiol. 77, 57–80 (2015). · DOI
  37. Nikoletopoulou, V., Papandreou, M. E. & Tavernarakis, N. Autophagy in the physiology and pathology of the central nervous system. Cell Death Differ. 22, 398–407 (2015). · DOI
  38. Yuan, Y. et al. Mitochondrial dysfunction accounts for aldosterone-induced epithelial-to-mesenchymal transition of renal proximal tubular epithelial cells. Free Radic. Biol. Med. 53, 30–43 (2012). · DOI
  39. Gautier, L., Cope, L., Bolstad, B. M. & Irizarry, R. A. affy–analysis of Affymetrix GeneChip data at the probe level. Bioinformatics 20, 307–315 (2004). · DOI
  40. Irizarry, R. A. et al. Exploration, normalization, and summaries of high density oligonucleotide array probe level data. Biostatistics 4, 249–264 (2003). · DOI · Paper page
  41. Baldi, P. & Long, A. D. A Bayesian framework for the analysis of microarray expression data: regularized t-test and statistical inferences of gene changes. Bioinformatics 17, 509–519 (2001). · DOI
  42. Kuhn, R. M., Haussler, D. & Kent, W. J. The UCSC genome browser and associated tools. Brief. Bioinform. 14, 144–161 (2013). · DOI · Paper page
  43. Wasserman, W. W. & Sandelin, A. Applied bioinformatics for the identification of regulatory elements. Nat. Rev. Genet. 5, 276–287 (2004). · DOI
  44. Sardiello, M. et al. A gene network regulating lysosomal biogenesis and function. Science 325, 473–477 (2009). · DOI · Paper page
  45. Ashley, N., Harris, D. & Poulton, J. Detection of mitochondrial DNA depletion in living human cells using PicoGreen staining. Exp. Cell Res. 303, 432–446 (2005). · DOI
  46. Hammond, G. R., Schiavo, G. & Irvine, R. F. Immunocytochemical techniques reveal multiple, distinct cellular pools of PtdIns4P and PtdIns(4,5)P2 . Biochem. J. 422, 23–35 (2009). · DOI
  47. Carpenter, A. E. et al. CellProfiler: image analysis software for identifying and quantifying cell phenotypes. Genome Biol. 7, R100 (2006). · DOI
  48. Ladoire, S. et al. Immunohistochemical detection of cytoplasmic LC3 puncta in human cancer specimens. Autophagy 8, 1175–1184 (2012). · DOI
  49. Polishchuk, E. V., Polishchuk, R. S. & Luini, A. Correlative light-electron microscopy as a tool to study in vivo dynamics and ultrastructure of intracellular structures. Methods Mol. Biol. 931, 413–422 (2013). · DOI

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Metadata

Authors
De Leo, M. G., Staiano, L., Vicinanza, M., Luciani, A., Carissimo, A., Mutarelli, M., Di Campli, A., Polishchuk, E., Di Tullio, G., Morra, V., Levtchenko, E., Oltrabella, F., Starborg, T., Santoro, M., di Bernardo, D., Devuyst, O., Lowe, M., Medina, D. L., Ballabio, A., & De Matteis, M. A.
Venue
Nature Cell Biology
Published
2016-07-11
Volume
18
Issue
8
Pages
839-850
ISSN
  • 1465-7392
  • 1476-4679
Cited by
165
References
15
Language
en

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