Activation of the Raf-MEK-ERK pathway is required for neutrophil extracellular trap formation

Neutrophil Extracellular Traps Kill Bacteria

Brinkmann, V., Reichard, U., Goosmann, C., Fauler, B., Uhlemann, Y., Weiss, D. S., Weinrauch, Y., & Zychlinsky, A. (2004) · Science · doi:10.1126/science.1092385 · Cited by 10,268 · see citing works

Novel cell death program leads to neutrophil extracellular traps

Fuchs, T. A., Abed, U., Goosmann, C., Hurwitz, R., Schulze, I., Wahn, V., Weinrauch, Y., Brinkmann, V., & Zychlinsky, A. (2007) · The Journal of Cell Biology · doi:10.1083/jcb.200606027 · Cited by 3,197 · see citing works

Identification of a Novel Inhibitor of Mitogen-activated Protein Kinase Kinase

Favata, M. F., Horiuchi, K. Y., Manos, E. J., Daulerio, A. J., Stradley, D. A., Feeser, W. S., Dyk, D. E. V., Pitts, W. J., Earl, R. A., Hobbs, F. W., et al. (1998) · Journal of Biological Chemistry · doi:10.1074/jbc.273.29.18623 · Cited by 3,016 · see citing works

Neutrophils and immunity: challenges and opportunities

Nathan, C. (2006) · Nature reviews. Immunology · doi:10.1038/nri1785 · Cited by 2,971 · see citing works

Staurosporine, a potent inhibitor of phospholipidCa++dependent protein kinase

Tamaoki, T., Nomoto, H., TAKAHASHI, I., Kato, Y., Morimoto, M., & Tomita, F. (1986) · Biochemical and Biophysical Research Communications · doi:10.1016/0006-291x(86)90008-2 · Cited by 2,452 · see citing works

Platelet TLR4 activates neutrophil extracellular traps to ensnare bacteria in septic blood

Clark, S. R., Ma, A. C., Tavener, S. A., McDonald, B., Goodarzi, Z., Kelly, M. M., Patel, K. D., Chakrabarti, S., McAvoy, E., Sinclair, G. D., et al. (2007) · Nature Medicine · doi:10.1038/nm1565 · Cited by 2,309 · see citing works

Netting neutrophils in autoimmune small-vessel vasculitis

Kessenbrock, K., Krumbholz, M., Schönermarck, U., Back, W. E., Gross, W. L., Werb, Z., Gröne, H., Brinkmann, V., & Jenne, D. E. (2009) · Nature Medicine · doi:10.1038/nm.1959 · Cited by 1,650 · see citing works

Impairment of neutrophil extracellular trap degradation is associated with lupus nephritis

Hakkim, A., Fürnrohr, B. G., Amann, K., Laube, B., Abed, U. A., Brinkmann, V., i, M. H., Voll, R. E., & Zychlinsky, A. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0909927107 · Cited by 1,473 · see citing works

Meaningful relationships: the regulation of the Ras/Raf/MEK/ERK pathway by protein interactions

Kölch, W. (2000) · Biochemical Journal · doi:10.1042/bj3510289 · Cited by 1,443 · see citing works

Beneficial suicide: why neutrophils die to make NETs

Brinkmann, V., & Zychlinsky, A. (2007) · Nature Reviews Microbiology · doi:10.1038/nrmicro1710 · Cited by 937 · see citing works

NETs: a new strategy for using old weapons

Papayannopoulos, V., & Zychlinsky, A. (2009) · Trends in Immunology · doi:10.1016/j.it.2009.07.011 · Cited by 634 · see citing works

Restoration of NET formation by gene therapy in CGD controls aspergillosis

Bianchi, M., Hakkim, A., Brinkmann, V., Siler, U., Seger, R. A., Zychlinsky, A., & Reichenbach, J. (2009) · Blood · doi:10.1182/blood-2009-05-221606 · Cited by 593 · see citing works

Studies on the inhibitory mechanism of iodonium compounds with special reference to neutrophil NADPH oxidase

O’Donnell, V. B., Tew, D. G., Jones, O. T. G., & ENGLAND, P. J. (1993) · Biochemical Journal · doi:10.1042/bj2900041 · Cited by 590 · see citing works

Living dangerously: how Helicobacter pylori survives in the human stomach

Montecucco, C., & Rappuoli, R. (2001) · Nature Reviews Molecular Cell Biology · doi:10.1038/35073084 · Cited by 538 · see citing works

Small-molecule inhibition of APT1 affects Ras localization and signaling.

Dekker, F., Rocks, O., Vartak, N., Menninger, S., Hedberg, C., Balamurugan, R., Wetzel, S., Renner, S., Gerauer, M., Schölermann, B., et al. (2010) · Nature Chemical Biology · doi:10.1038/nchembio.362 · Cited by 401 · see citing works

Mcl-1 Expression in Human Neutrophils: Regulation by Cytokines and Correlation With Cell Survival

MOULDING, D. A., Quayle, J. A., Hart, C. A., & Edwards, S. W. (1998) · Blood · doi:10.1182/blood.v92.7.2495 · Cited by 356 · see citing works

The antiapoptotic protein Mcl-1 is essential for the survival of neutrophils but not macrophages

Dzhagalov, I. L., John, A. L. S., & He, Y.-W. (2006) · Blood · doi:10.1182/blood-2006-03-013771 · Cited by 279 · see citing works

Activation of p38 in Stimulated Human Neutrophils: Phosphorylation of the Oxidase Component p47 by p38 and ERK but Not by JNK

Benna, J. E., Han, J., Park, J., Schmid, E., Ulevitch, R. J., & BABIOR, B. M. (1996) · Archives of Biochemistry and Biophysics · doi:10.1006/abbi.1996.0470 · Cited by 249 · see citing works

Divergence and complexities in DAG signaling: looking beyond PKC

Yang, C., & Kazanietz, M. G. (2003) · Trends in Pharmacological Sciences · doi:10.1016/j.tips.2003.09.003 · Cited by 232 · see citing works

LEUKOKINETIC STUDIES. II. A METHOD FOR LABELING GRANULOCYTES IN VITRO WITH RADIOACTIVE DIISOPROPYLFLUOROPHOSPHATE (DFP32)*

Mauer, A. M., Athens, J. W., Ashenbrucker, H., Cartwright, G. E., & Wintrobe, M. M. (1960) · Journal of Clinical Investigation · doi:10.1172/jci104167 · Cited by 230 · see citing works

The discovery of potent cRaf1 kinase inhibitors

Lackey, K. E., Cory, M., Davis, R. G., et al. (2000) · Bioorganic & Medicinal Chemistry Letters · doi:10.1016/s0960-894x(99)00668-x · Cited by 206 · see citing works

Analysis of the eukaryotic prenylome by isoprenoid affinity tagging

Nguyen, U. T. T., Guo, Z., Delon, C., Wu, Y., Deraeve, C., Fränzel, B., Bon, R. S., Blankenfeldt, W., Goody, R. S., Waldmann, H., et al. (2009) · Nature Chemical Biology · doi:10.1038/nchembio.149 · Cited by 176 · see citing works

The platelet activating factor (PAF) signaling cascade in systemic inflammatory responses

Yost, C. C., Weyrich, A. S., & Zimmerman, G. A. (2010) · Biochimie · doi:10.1016/j.biochi.2010.02.011 · Cited by 141 · see citing works

Modulation of neutrophil oxidative responses to soluble stimuli by platelet-activating factor

Gay, J., Beckman, J., Zaboy, K., et al. (1986) · Blood · doi:10.1182/blood.v67.4.931.931 · Cited by 97 · see citing works

The neutrophil‐activating protein of Helicobacter pylori (HP‐NAP) activates the MAPK pathway in human neutrophils

Nishioka, H., Baesso, I., Semenzato, G., et al. (2003) · European Journal of Immunology · doi:10.1002/eji.200323726 · Cited by 54 · see citing works

Molecular mechanisms of cell death: recommendations of the nomenclature committee on cell death 2018.

Galluzzi, L., Vitale, I., Aaronson, S. A., Abrams, J. M., Adam, D., Agostinis, P., Alnemri, E. S., Altucci, L., Amelio, I., Andrews, D. W., et al. (2018) · Cell Death & Differentiation · doi:10.1038/s41418-017-0012-4 · Cited by 6,680 · see citing works

Infection-induced NETosis is a dynamic process involving neutrophil multitasking in vivo

Yipp, B. G., Petri, B., Salina, D., Jenne, C. N., Scott, B. N. V., Zbytnuik, L. D., Pittman, K., Asaduzzaman, M., Wu, K., Meijndert, H. C., et al. (2012) · Nature Medicine · doi:10.1038/nm.2847 · Cited by 1,169 · see citing works

Neutrophils sense microbe size and selectively release neutrophil extracellular traps in response to large pathogens

Branzk, N., Lubojemska, A., Hardison, S. E., Wang, Q., Gutierrez, M. G., Brown, G. D., & Papayannopoulos, V. (2014) · Nature Immunology · doi:10.1038/ni.2987 · Cited by 1,037 · see citing works

Aggregated neutrophil extracellular traps limit inflammation by degrading cytokines and chemokines

Schauer, C., Janko, C., Munoz, L. E., Zhao, Y., Kienhöfer, D., Frey, B., Lell, M., Manger, B., Rech, J., Naschberger, E., et al. (2014) · Nature Medicine · doi:10.1038/nm.3547 · Cited by 998 · see citing works

Neutrophils and NETS in modulating acute and chronic inflammation

Castanheira, F. V. S., & Kubes, P. (2019) · Blood · doi:10.1182/blood-2018-11-844530 · Cited by 792 · see citing works

NETosis: Molecular Mechanisms, Role in Physiology and Pathology

Vorobjeva, N. V., & Chernyak, B. V. (2020) · Biochemistry (Moscow) · doi:10.1134/s0006297920100065 · Cited by 559 · see citing works

Interference of Aspergillus fumigatus with the immune response

Heinekamp, T., Schmidt, H., Lapp, K., Pähtz, V., Shopova, I., Köster-Eiserfunke, N., Krüger, T., Kniemeyer, O., & Brakhage, A. A. (2015) · Seminars in Immunopathology · doi:10.1007/s00281-014-0465-1 · Cited by 123 · see citing works

Age is the work of art? Impact of neutrophil and organism age on neutrophil extracellular trap formation

Ortmann, W., & Kolaczkowska, E. (2018) · Cell and Tissue Research · doi:10.1007/s00441-017-2751-4 · Cited by 80 · see citing works

UVA and UVB Radiation Induce the Formation of Neutrophil Extracellular Traps by Human Polymorphonuclear Cells

Zawrotniak, M., Bartnicka, D., & Rapala-Kozik, M. (2019) · Journal of Photochemistry and Photobiology B Biology · doi:10.1016/j.jphotobiol.2019.111511 · Cited by 41 · see citing works

The Expanding Role of Extracellular Traps in Inflammation and Autoimmunity: The New Players in Casting Dark Webs

Huang, S. U.-S., & O’Sullivan, K. M. (2022) · doi:10.20944/preprints202203.0021.v1 · Cited by 65 · see citing works

A novel rapid Neutrophil Extracellular Trap (NET) release mechanism without neutrophil death

Kubes⁎, P. (2012) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2012.08.097

Neutrophil elastase‐deficient mice form neutrophil extracellular traps in an experimental model of deep vein thrombosis

Martinod, K., Witsch, T., Farley, K., Gallant, M., Remold‐O'Donnell, E., & Wagner, D. D. (2016) · Journal of Thrombosis and Haemostasis · doi:10.1111/jth.13239 · Cited by 188 · see citing works

[Techniques for detection and role of extracellular neutrophil traps in antimicrobial protection].

Dolgushin, I. I., Shishkova, I. S., Savochkina, A. I., et al. (2010) · PubMed

Quantifying neutrophil extracellular trap release in a combined infection–inflammation NET-array device

Datla, U. S., Vundurthy, B., Hook, J. S., Menon, N., Bagtash, H. R., Shihabeddin, T. Z., Schmidtke, D. W., Moreland, J. G., Radic, M. Z., & Jones, C. N. (2024) · Lab on a Chip · doi:10.1039/d3lc00648d · Cited by 13 · see citing works

Mitochondria-induced formation of neutrophil extracellular traps is enhanced in the elderly via Toll-like receptor 9

Pastorek, M., Konečná, B., Janko, J., Janovičová, Ľ., Podracká, Ľ., Záhumenský, J., Šteňová, E., Dúbrava, M., Hodosy, J., Vlková, B., et al. (2023) · Journal of Leukocyte Biology · doi:10.1093/jleuko/qiad101 · Cited by 16 · see citing works