Common variants at 30 loci contribute to polygenic dyslipidemia

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Items 101–131 of 131

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6. ANGPTL3 blockade with a human monoclonal antibody reduces plasma lipids in dyslipidemic mice and monkeys
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7. A Genetic Risk Score Is Associated With Incident Cardiovascular Disease and Coronary Artery Calcium: The Framingham Heart Study
   Thanassoulis, George, Peloso, Gina M., Pencina, Michael J., Hoffmann, Udo, Fox, Caroline S., Cupples, L. Adrienne, Levy, Daniel, D'Agostino, Ralph B., Hwang, Shih-Jen, O'Donnell, Christopher J. · 2012 · Circulation: Cardiovascular Genetics
8. Genetics of schizophrenia: new findings and challenges
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9. Ion mobility analysis of lipoprotein subfractions identifies three independent axes of cardiovascular risk.
   Musunuru, Kiran, Orho-Melander, Marju, Caulfield, Michael P., Li, Shuguang, Salameh, Wael A., Reitz, Richard E., Berglund, Göran, Hedblad, Bo, Engström, Gunnar, Williams, Paul T. et al. · 2009 · Arteriosclerosis, Thrombosis, and Vascular Biology
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11. Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study
    Voight, Benjamin F, Peloso, Gina M, Orho-Melander, Marju, Frikke-Schmidt, Ruth, Barbalic, Maja, Jensen, Majken K, Hindy, George, Hólm, Hilma, Ding, Eric L, Johnson, Toby et al. · 2012 · The Lancet
12. Glucokinase regulatory protein: complexity at the crossroads of triglyceride and glucose metabolism
    Raimondo, Anne, Rees, Matthew G., Gloyn, Anna L. · 2015 · Current Opinion in Lipidology
13. Dyslipidemia, inflammation, calcification, and adiposity in aortic stenosis: a genome-wide study
    Yu Chen, Hao, Dina, Christian, Small, Aeron M, Shaffer, Christian M, Levinson, Rebecca T, Helgadóttir, Anna, Capoulade, Romain, Munter, Hans Markus, Martinsson, Andreas, Cairns, Benjamin J et al. · 2023 · European Heart Journal
14. MafB promotes atherosclerosis by inhibiting foam-cell apoptosis
    Hamada, Michito, Nakamura, Megumi, Tran, Mai Thi Nhu, Moriguchi, Takashi, Hong, Cynthia, Ohsumi, Takayuki, Dinh, Tra Thi Huong, Kusakabe, Manabu, Hattori, Motochika, Katsumata, Tokio et al. · 2014 · Nature Communications
15. The genetics of familial combined hyperlipidaemia
    Brouwers, Martijn C. G. J., van Greevenbroek, Marleen M. J., Stehouwer, Coen D. A., de Graaf, Jacqueline, Stalenhoef, Anton F. H. · 2012 · Nature Reviews Endocrinology
16. A Proprotein Convertase Subtilisin-like/Kexin Type 9 (PCSK9) C-terminal Domain Antibody Antigen-binding Fragment Inhibits PCSK9 Internalization and Restores Low Density Lipoprotein Uptake
    Ni, Yan G., Condra, Jon H., Orsatti, Laura, Shen, Xun, Di Marco, Stefania, Pandit, Shilpa, Bottomley, Matthew J., Ruggeri, Lionello, Cummings, Richard T., Cubbon, Rose M. et al. · 2010 · Journal of Biological Chemistry
17. Novel insights into genetics and clinics of the HNF1A-MODY
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18. ARMS2/HTRA1 locus can confer differential susceptibility to the advanced subtypes of age-related macular degeneration
    Sobrin, Lucia, Reynolds, Robyn, Yu, Yi, Fagerness, Jesen, Leveziel, Nicolas, Bernstein, Paul S., Souied, Eric H., Daly, Mark J., Seddon, Johanna M. · 2011 · American Journal of Ophthalmology
19. Genome-wide association studies and the genetic dissection of complex traits
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20. Blockade of Tim-1 and Tim-4 Enhances Atherosclerosis in Low-Density Lipoprotein Receptor–Deficient Mice
    Foks, Amanda C., Engelbertsen, Daniel, Kuperwaser, Felicia, Alberts-Grill, Noah, Gonen, Ayelet, Witztum, Joseph L., Lederer, James, Jarolim, Petr, DeKruyff, Rosemarie H., Freeman, Gordon J. et al. · 2016 · Arteriosclerosis, Thrombosis, and Vascular Biology
21. Meta-Analysis of Genome-Wide Association Studies
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22. Utility of genetic determinants of lipids and cardiovascular events in assessing risk
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23. Hepatic ABCA1 and VLDL triglyceride production
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24. Precision pharmacotherapy: psychiatry’s future direction in preventing, diagnosing, and treating mental disorders
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25. Association of cholesteryl ester transfer protein (CETP) gene polymorphism, high density lipoprotein cholesterol and risk of coronary artery disease: a meta-analysis using a Mendelian randomization approach
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26. Functional validation of new pathways in lipoprotein metabolism identified by human genetics
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27. Obesity and cancer—extracellular matrix, angiogenesis, and adrenergic signaling as unusual suspects linking the two diseases
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28. Therapeutic targets of triglyceride metabolism as informed by human genetics
    Bauer, Robert C., Khetarpal, Sumeet A., Hand, Nicholas J., Rader, Daniel J. · 2016 · Trends in Molecular Medicine
29. Novel loci affecting iron homeostasis and their effects in individuals at risk for hemochromatosis
    Benyamin, Beben, Esko, Tonu, Ried, Janina S., Radhakrishnan, Aparna, Vermeulen, Sita H., Traglia, Michela, Gögele, Martin, Anderson, Denise, Broer, Linda, Podmore, Clara et al. · 2014 · Nature Communications
30. Genetic studies of plasma analytes identify novel potential biomarkers for several complex traits
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31. High-density lipoprotein-related cholesterol metabolism in Alzheimer's disease
    Pedrini, Steve, Chatterjee, Pratishtha, Hone, Eugene, Martins, Ralph N. · 2021 · Journal of Neurochemistry