The role of site accessibility in microRNA target recognition

The functions of animal microRNAs

Ambros, V. (2004) · Nature · doi:10.1038/nature02871 · Cited by 10,728

Oncomirs—MicroRNAs with a role in cancer

Esquela-Kerscher, A., & Slack, F. J. (2006) · Nature Reviews Cancer · doi:10.1038/nrc1840 · Cited by 5,884

Prediction of Mammalian MicroRNA Targets

Lewis, B. P., Shih, I.-H., Jones-Rhoades, M. W., Bartel, D. P., & Burge, C. B. (2003) · Cell · doi:10.1016/s0092-8674(03)01018-3 · Cited by 5,199

MicroRNA targets in Drosophila

Enright, A. J., John, B., Gaul, U., Tuschl, T., Sander, C., & Marks, D. S. (2003) · Genome Biology · doi:10.1186/gb-2003-5-1-r1 · Cited by 3,597

Fast and effective prediction of microRNA/target duplexes

REHMSMEIER, M., STEFFEN, P., HÖCHSMANN, M., & GIEGERICH, R. (2004) · RNA · doi:10.1261/rna.5248604 · Cited by 2,560

Principles of MicroRNA–Target Recognition

Brennecke, J., Stark, A., Russell, R. B., & Cohen, S. M. (2005) · PLoS Biology · doi:10.1371/journal.pbio.0030085 · Cited by 2,431

Vienna RNA secondary structure server

Hofacker, I. L. (2003) · Nucleic Acids Research · doi:10.1093/nar/gkg599 · Cited by 2,362

Control of translation and mRNA degradation by miRNAs and siRNAs: Table 1.

Valencia-Sanchez, M. A., Liu, J., Hannon, G. J., & Parker, R. (2006) · Genes & Development · doi:10.1101/gad.1399806 · Cited by 2,060

bantam Encodes a Developmentally Regulated microRNA that Controls Cell Proliferation and Regulates the Proapoptotic Gene hid in Drosophila

Brennecke, J., Hipfner, D. R., Stark, A., Russell, R. B., & Cohen, S. M. (2003) · Cell · doi:10.1016/s0092-8674(03)00231-9 · Cited by 2,042

Specificity of microRNA target selection in translational repressionPreprint

Doench, J. G., & Sharp, P. A. (2004) · Genes & Development · doi:10.1101/gad.1184404 · Cited by 1,685

MicroRNAs: Target Recognition and Regulatory Functions

Bartel, D. P. (2009) · Cell · doi:10.1016/j.cell.2009.01.002 · Cited by 20,068

Predicting effective microRNA target sites in mammalian mRNAs

Agarwal, V., Bell, G. W., Nam, J.-W., & Bartel, D. P. (2015) · eLife · doi:10.7554/elife.05005 · Cited by 7,318

The Immune Landscape of Cancer

Thorsson, V., Gibbs, D. L., Brown, S. D., Wolf, D., Bortone, D. S., Ou Yang, T.-H., Porta-Pardo, E., Gao, G. F., Plaisier, C. L., Eddy, J. A., et al. (2018) · Immunity · doi:10.1016/j.immuni.2018.03.023 · Cited by 5,870

starBase v2.0: decoding miRNA-ceRNA, miRNA-ncRNA and protein–RNA interaction networks from large-scale CLIP-Seq data

Li, J.-H., Liu, S., Zhou, H., Qu, L.-H., & Yang, J.-H. (2014) · Nucleic Acids Research · doi:10.1093/nar/gkt1248 · Cited by 4,686

Untitled work

(2008) · doi:10.1038/nrg2290 · Cited by 5,199

The impact of microRNAs on protein output

Baek, D., Villén, J., Shin, C., Camargo, F. D., Gygi, S. P., & Bartel, D. P. (2008) · Nature · doi:10.1038/nature07242 · Cited by 3,592

Regulation of microRNA function in animals

Gebert, L. F. R., & MacRae, I. J. (2019) · Nature Reviews Molecular Cell Biology · doi:10.1038/s41580-018-0045-7 · Cited by 2,284

Endogenous microRNA sponges: evidence and controversy

Thomson, D. W., & Dinger, M. E. (2016) · Nature Reviews Genetics · doi:10.1038/nrg.2016.20 · Cited by 2,185

psRNATarget: a plant small RNA target analysis server

Dai, X., & Zhao, P. X. (2011) · Nucleic Acids Research · doi:10.1093/nar/gkr319 · Cited by 1,847

MicroRNA dysregulation in cancer: diagnostics, monitoring and therapeutics. A comprehensive review

Iorio, M. V., & Croce, C. M. (2012) · EMBO Molecular Medicine · doi:10.1002/emmm.201100209 · Cited by 1,778

miR-126 Regulates Angiogenic Signaling and Vascular Integrity

Fish, J. E., Santoro, M. M., Morton, S. U., Yu, S., Yeh, R.-F., Wythe, J. D., Ivey, K. N., Bruneau, B. G., Stainier, D. Y. R., & Srivastava, D. (2008) · Developmental Cell · doi:10.1016/j.devcel.2008.07.008 · Cited by 1,515

miRWalk – Database: Prediction of possible miRNA binding sites by “walking” the genes of three genomes

Dweep, H., Sticht, C., Pandey, P., & Gretz, N. (2011) · Journal of Biomedical Informatics · doi:10.1016/j.jbi.2011.05.002 · Cited by 1,707

MicroRNAs in Cancer

Leva, G. D., Garofalo, M., & Croce, C. M. (2013) · Annual Review of Pathology Mechanisms of Disease · doi:10.1146/annurev-pathol-012513-104715 · Cited by 1,705

Comprehensive modeling of microRNA targets predicts functional non-conserved and non-canonical sites

Betel, D., Koppal, A., Agius, P., Sander, C., & Leslie, C. (2010) · Genome Biology · doi:10.1186/gb-2010-11-8-r90 · Cited by 1,592

miRecords: an integrated resource for microRNA-target interactions

Xiao, F., Zuo, Z., Cai, G., Kang, S., Gao, X., & Li, T. (2008) · Nucleic Acids Research · doi:10.1093/nar/gkn851 · Cited by 1,446

miR2Disease: a manually curated database for microRNA deregulation in human disease

Jiang, Q., Wang, Y., Hao, Y., Juan, L., Teng, M., Zhang, X., Li, M., Wang, G., & Liu, Y. (2008) · Nucleic Acids Research · doi:10.1093/nar/gkn714 · Cited by 1,430

miRTarBase: a database curates experimentally validated microRNA–target interactions

Hsu, S., Lin, F., Wu, W., Liang, C., Huang, W., Chan, W., Tsai, W.-T., Chen, G.-Z., Lee, C., Chiu, C.-M., et al. (2010) · Nucleic Acids Research · doi:10.1093/nar/gkq1107 · Cited by 1,400

Mapping the Human miRNA Interactome by CLASH Reveals Frequent Noncanonical Binding

Helwak, A., Kudla, G., Dudnakova, T., & Tollervey, D. (2013) · Cell · doi:10.1016/j.cell.2013.03.043 · Cited by 1,269

Lymphoproliferative disease and autoimmunity in mice with increased miR-17-92 expression in lymphocytes

Xiao, C., Srinivasan, L., Calado, D. P., Patterson, H. C., Zhang, B., Wang, J., Henderson, J., Kutok, J. L., & Rajewsky, K. (2008) · Nature Immunology · doi:10.1038/ni1575 · Cited by 1,248

Diversifying microRNA sequence and function

Ameres, S. L., & Zamore, P. D. (2013) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm3611 · Cited by 1,175

MicroRNAs in Development and Disease

Sayed, D. H., & Abdellatif, M. (2011) · Physiological Reviews · doi:10.1152/physrev.00006.2010 · Cited by 1,101

miRTarBase update 2014: an information resource for experimentally validated miRNA-target interactions

Hsu, S., Tseng, Y., Shrestha, S., Lin, Y., Khaleel, A., Chou, C., Chu, C.-F., Huang, H., Lin, C.-M., Ho, S.-Y., et al. (2013) · Nucleic Acids Research · doi:10.1093/nar/gkt1266 · Cited by 1,044

Weak seed-pairing stability and high target-site abundance decrease the proficiency of lsy-6 and other microRNAs

Garcia, D. M., Baek, D., Shin, C., Bell, G. W., Grimson, A., & Bartel, D. P. (2011) · Nature Structural & Molecular Biology · doi:10.1038/nsmb.2115 · Cited by 872

starBase: a database for exploring microRNA–mRNA interaction maps from Argonaute CLIP-Seq and Degradome-Seq data

Yang, J., Li, J., Shao, P., Zhou, H., Chen, Y., & Qu, L. (2010) · Nucleic Acids Research · doi:10.1093/nar/gkq1056 · Cited by 825

MicroRNAs: New Biomarkers for Diagnosis, Prognosis, Therapy Prediction and Therapeutic Tools for Breast Cancer

Bertoli, G. R., Cava, C., & Castiglioni, I. (2015) · Theranostics · doi:10.7150/thno.11543 · Cited by 836

MicroRNA-122 plays a critical role in liver homeostasis and hepatocarcinogenesis

Tsai, W.-C., Hsu, S., Hsu, C.-S., Lai, T., Chen, S.-J., Shen, R., Huang, Y., Chen, H., Lee, C.-H., Tsai, T., et al. (2012) · Journal of Clinical Investigation · doi:10.1172/jci63455 · Cited by 815

The multiMiR R package and database: integration of microRNA–target interactions along with their disease and drug associations

Ru, Y., Kechris, K. J., Tabakoff, B., Hoffman, P. L., Radcliffe, R. A., Bowler, R. P., Mahaffey, S. B., Rossi, S., Călin, G. A., Bemis, L., et al. (2014) · Nucleic Acids Research · doi:10.1093/nar/gku631 · Cited by 805

Prediction of functional microRNA targets by integrative modeling of microRNA binding and target expression data

Liu, W., & Wang, X. (2019) · Genome biology · doi:10.1186/s13059-019-1629-z · Cited by 810

miR-155 gene: A typical multifunctional microRNA

Faraoni, I., Antonetti, F. R., Cardone, J., & Bonmassar, E. (2009) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2009.02.013 · Cited by 815

Genome-wide measurement of RNA secondary structure in yeast

Kertesz, M., Wan, Y., Mazor, E., Rinn, J. L., Nutter, R. C., Chang, H. Y., & Segal, E. (2010) · Nature · doi:10.1038/nature09322 · Cited by 769

An Extensive MicroRNA-Mediated Network of RNA-RNA Interactions Regulates Established Oncogenic Pathways in Glioblastoma

Sumazin, P., Yang, X., Chiu, H., Chung, W., Iyer, A. P., Llobet‐Navàs, D., Rajbhandari, P., Bansal, M., Guarnieri, P., Silva, J., et al. (2011) · Cell · doi:10.1016/j.cell.2011.09.041 · Cited by 695

MicroRNA-155 Is Regulated by the Transforming Growth Factor β/Smad Pathway and Contributes to Epithelial Cell Plasticity by Targeting RhoA

Kong, W. W., Yang, H., He, L., Zhao, J., Coppola, D., Dalton, W. S., & Cheng, J. Q. (2008) · Molecular and Cellular Biology · doi:10.1128/mcb.00941-08 · Cited by 698

Revisiting the principles of microRNA target recognition and mode of action

Brodersen, P., & Voinnet, O. (2009) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm2619 · Cited by 683

MicroRNA Related Polymorphisms and Breast Cancer Risk

Khan, S., Greco, D., Michailidou, K., Milne, R. L., Muranen, T., Heikkinen, T., Aaltonen, K., Dennis, J., Bolla, M. K., Liu, J., et al. (2014) · PLoS ONE · doi:10.1371/journal.pone.0109973 · Cited by 639

Identification and consequences of miRNA–target interactions — beyond repression of gene expression

Hausser, J., & Zavolan, M. (2014) · Nature Reviews Genetics · doi:10.1038/nrg3765 · Cited by 633

Hypoxia-Inducible mir-210 Regulates Normoxic Gene Expression Involved in Tumor Initiation

Huang, X., Ding, L., Bennewith, K. L., Tong, R. T., Welford, S. M., Ang, K. K., Story, M. D., Le, Q., & Giaccia, A. J. (2009) · Molecular Cell · doi:10.1016/j.molcel.2009.09.006 · Cited by 634

Trends in the development of miRNA bioinformatics tools

Chen, L., Heikkinen, L., Wang, C., Yang, Y., Sun, H., & Wong, G. (2018) · Briefings in Bioinformatics · doi:10.1093/bib/bby054 · Cited by 612

NSun2-Mediated Cytosine-5 Methylation of Vault Noncoding RNA Determines Its Processing into Regulatory Small RNAs

Hussain, S., Sajini, A. A., Blanco, S., Dietmann, S., Lombard, P., Sugimoto, Y., Paramor, M., Gleeson, J. G., Odom, D. T., Ule, J., et al. (2013) · Cell Reports · doi:10.1016/j.celrep.2013.06.029 · Cited by 569

IntaRNA: efficient prediction of bacterial sRNA targets incorporating target site accessibility and seed regions

Busch, A., Richter, A. S., & Backofen, R. (2008) · Bioinformatics · doi:10.1093/bioinformatics/btn544 · Cited by 552

mirDIP 4.1—integrative database of human microRNA target predictions

Tokár, T., Pastrello, C., Rossos, A. E. M., Abovsky, M., Hauschild, A.-C., Tsay, M. J., Lu, R., & Jurišica, I. (2017) · Nucleic Acids Research · doi:10.1093/nar/gkx1144 · Cited by 577

Identifying miRNAs, targets and functions

Liu, B., Li, J., & Cairns, M. J. (2014) · Briefings in Bioinformatics · doi:10.1093/bib/bbs075 · Cited by 563

DIANA-microT web server: elucidating microRNA functions through target prediction

Maragkakis, M., Reczko, M., Simossis, V., Alexiou, P., Papadopoulos, G. L., Dalamagas, T., Giannopoulos, G., Goumas, G., Koukis, E., Kourtis, K., et al. (2009) · Nucleic Acids Res. · doi:10.1093/nar/gkp292 · Cited by 405

LncRNADisease 2.0: an updated database of long non-coding RNA-associated diseases

Bao, Z., Yang, Z., Huang, Z., Zhou, Y., Cui, Q., & Dong, D. (2018) · Nucleic Acids Research · doi:10.1093/nar/gky905 · Cited by 559

Prediction of both conserved and nonconserved microRNA targets in animals

Wang, X., & Naqa, I. E. (2007) · Bioinformatics · doi:10.1093/bioinformatics/btm595 · Cited by 536

Mutations in the seed region of human miR-96 are responsible for nonsyndromic progressive hearing loss

Mencía, Á., Modamio-Høybjør, S., Redshaw, N., Morín, M., Mayo-Merino, F., Olavarrieta, L., Aguirre, L. A., del Castillo, I., Steel, K. P., Dalmay, T., et al. (2009) · Nature Genetics · doi:10.1038/ng.355 · Cited by 550

MicroRNA Directly Enhances Mitochondrial Translation during Muscle Differentiation

Zhang, X., Zuo, X., Yang, B., Li, Z., Xue, Y., Zhou, Y., Huang, J. S., Zhao, X., Zhou, J., Yan, Y., et al. (2014) · Cell · doi:10.1016/j.cell.2014.05.047 · Cited by 505

Identification of Nutrient-Responsive Arabidopsis and Rapeseed MicroRNAs by Comprehensive Real-Time Polymerase Chain Reaction Profiling and Small RNA Sequencing

Pant, B. D., Musialak‐Lange, M., Nuc, P., May, P., Buhtz, A., Kehr, J., Walther, D., & Scheible, W. (2009) · PLANT PHYSIOLOGY · doi:10.1104/pp.109.139139 · Cited by 497

Desperately seeking microRNA targets

Thomas, M., Lieberman, J., & Lal, A. (2010) · Nature Structural & Molecular Biology · doi:10.1038/nsmb.1921 · Cited by 487

Insights into RNA structure and function from genome-wide studies

Mortimer, S., Kidwell, M. A., & Doudna, J. A. (2014) · Nature Reviews Genetics · doi:10.1038/nrg3681 · Cited by 482

APF lncRNA regulates autophagy and myocardial infarction by targeting miR-188-3p

Wang, K., Liu, C.-Y., Zhou, L.-Y., Wang, J.-X., Wang, M., Zhao, B., Zhao, W.-K., Xu, S.-J., Fan, L.-H., Zhang, X.-J., et al. (2015) · Nature Communications · doi:10.1038/ncomms7779 · Cited by 473

RNAplex: a fast tool for RNA–RNA interaction search

Tafer, H., & Hofacker, I. L. (2008) · Bioinformatics · doi:10.1093/bioinformatics/btn193 · Cited by 475

Understanding the transcriptome through RNA structure

Wan, Y., Kertesz, M., Spitale, R. C., Segal, E., & Chang, H. Y. (2011) · Nature Reviews Genetics · doi:10.1038/nrg3049 · Cited by 482

Practical Aspects of microRNA Target Prediction

Witkos, T. M., Kościańska, E., & Krzyżosiak, W. J. (2011) · Current Molecular Medicine · doi:10.2174/156652411794859250 · Cited by 485

Common features of microRNA target prediction tools

Peterson, S. M., Thompson, J. A., Ufkin, M. L., Sathyanarayana, P., Liaw, L., & Congdon, C. B. (2014) · Frontiers in Genetics · doi:10.3389/fgene.2014.00023 · Cited by 484

MicroRNA-181b regulates NF-κB–mediated vascular inflammation

Sun, X., Icli, B., Wara, A. K., Belkin, N., He, S., Kobzik, L., Hunninghake, G. M., Pinilla-Vera, M., Blackwell, T. S., Baron, R. M., et al. (2012) · Journal of Clinical Investigation · doi:10.1172/jci61495 · Cited by 456

The Symbiodinium kawagutii genome illuminates dinoflagellate gene expression and coral symbiosis

Lin, S., Cheng, S., Song, B., Zhong, X., Lin, X., Li, W., Li, L., Zhang, Y., Zhang, H., Ji, Z., et al. (2015) · Science · doi:10.1126/science.aad0408 · Cited by 443

Circ2Traits: a comprehensive database for circular RNA potentially associated with disease and traits

Ghosal, S., Das, S., Sen, R., Basak, P., & Chakrabarti, J. (2013) · Frontiers in Genetics · doi:10.3389/fgene.2013.00283 · Cited by 444

Tools for Sequence-Based miRNA Target Prediction: What to Choose?

Riffo‐Campos, Á. L., Riquelme, I., & Brebi, P. (2016) · International Journal of Molecular Sciences · doi:10.3390/ijms17121987 · Cited by 450

CircAtlas: an integrated resource of one million highly accurate circular RNAs from 1070 vertebrate transcriptomes

Wu, W., Ji, P., & Zhao, F. (2020) · Genome biology · doi:10.1186/s13059-020-02018-y · Cited by 425

Virus-encoded microRNAs

Grundhoff, A. T., & Sullivan, C. S. (2011) · Virology · doi:10.1016/j.virol.2011.01.002 · Cited by 416

Using expression profiling data to identify human microRNA targets

Huang, J., Babak, T., Corson, T. W., Chua, G., Khan, S., Gallie, B. L., Hughes, T. R., Blencowe, B. J., Frey, B. J., & Morris, Q. (2007) · Nature Methods · doi:10.1038/nmeth1130 · Cited by 394

cis-Antisense RNA, Another Level of Gene Regulation in Bacteria

Georg, J., & Hess, W. R. (2011) · Microbiology and Molecular Biology Reviews · doi:10.1128/mmbr.00032-10 · Cited by 392

Argonaute Divides Its RNA Guide into Domains with Distinct Functions and RNA-Binding Properties

Wee, L. M., Flores-Jasso, C. F., Salomon, W. E., & Zamore, P. D. (2012) · Cell · doi:10.1016/j.cell.2012.10.036 · Cited by 398

miRmap: Comprehensive prediction of microRNA target repression strength

Vejnar, C. E., & Zdobnov, E. M. (2012) · Nucleic Acids Research · doi:10.1093/nar/gks901 · Cited by 396

Exposing synonymous mutations

Hunt, R., Simhadri, V. L., Iandoli, M., Sauna, Z. E., & Kimchi‐Sarfaty, C. (2014) · Trends in Genetics · doi:10.1016/j.tig.2014.04.006 · Cited by 397

Prioritization of disease microRNAs through a human phenome-microRNAome network

Jiang, Q., Hao, Y., Wang, G., Juan, L., Zhang, T., Teng, M., Liu, Y., & Wang, Y. (2010) · BMC Systems Biology · doi:10.1186/1752-0509-4-s1-s2 · Cited by 392

Single nucleotide polymorphisms and cancer susceptibility

Deng, N., Zhou, H., Fan, H., & Yuan, Y. (2017) · Oncotarget · doi:10.18632/oncotarget.22372 · Cited by 381

miRSystem: An Integrated System for Characterizing Enriched Functions and Pathways of MicroRNA Targets

Lu, T., Lee, C., Tsai, M., Chiu, Y., Hsiao, C. K., Lai, L., & Chuang, E. Y.-Y. (2012) · PLoS ONE · doi:10.1371/journal.pone.0042390 · Cited by 362

Highly Specific Gene Silencing by Artificial miRNAs in Rice

Warthmann, N., Chen, H., Ossowski, S., Weigel, D., & Hervé, P. (2008) · PLoS ONE · doi:10.1371/journal.pone.0001829 · Cited by 350

A functional polymorphism in the miR-146a gene and age of familial breast/ovarian cancer diagnosis

Shen, J., Ambrosone, C. B., DiCioccio, R. A., Odunsi, K. O., Lele, S., & Zhao, H. (2008) · Carcinogenesis · doi:10.1093/carcin/bgn172 · Cited by 347

Highly specific gene silencing by artificial microRNAs in the unicellular alga Chlamydomonas reinhardtii

Molnár, A., Bassett, A. R., Thuenemann, E. C., Schwach, F., Karkare, S., Ossowski, S., Weigel, D., & Baulcombe, D. C. (2008) · The Plant Journal · doi:10.1111/j.1365-313x.2008.03767.x · Cited by 348

Global Analyses of the Effect of Different Cellular Contexts on MicroRNA Targeting

Nam, J., Rissland, O. S., Koppstein, D., Abreu‐Goodger, C., Jan, C. H., Agarwal, V., Yıldırım, M. A., Rodríguez, A., & Bartel, D. P. (2014) · Molecular Cell · doi:10.1016/j.molcel.2014.02.013 · Cited by 337

MicroRNA-221/222 confers breast cancer fulvestrant resistance by regulating multiple signaling pathways

Rao, X., Leva, G. D., Li, M., Fang, F., Devlin, C. M., Hartman-Frey, C., Burow, M. E., Ivan, M., Croce, C. M., & Nephew, K. P. (2010) · Oncogene · doi:10.1038/onc.2010.487 · Cited by 348

Circular RNA hsa_circ_001783 regulates breast cancer progression via sponging miR-200c-3p

Liu, Z., Zhou, Y., Liang, G., Ling, Y., Tan, W., Tan, L., Andrews, R., Zhong, W., Zhang, X., Song, E., et al. (2019) · Cell Death and Disease · doi:10.1038/s41419-018-1287-1 · Cited by 336

miR-132 regulates antiviral innate immunity through suppression of the p300 transcriptional co-activator

Lagos, D., Pollara, G., Henderson, S., Gratrix, F., Fabani, M., Milne, R. S. B., Gotch, F., & Boshoff, C. (2010) · Nature Cell Biology · doi:10.1038/ncb2054 · Cited by 296

The circular RNA circBIRC6 participates in the molecular circuitry controlling human pluripotency

Yu, C.-Y., Li, T.-C., Wu, Y.-Y., Yeh, C.-H., Chiang, W., Chuang, C.-Y., & Kuo, H.-C. (2017) · Nature Communications · doi:10.1038/s41467-017-01216-w · Cited by 336

Accurate microRNA target prediction correlates with protein repression levels

Maragkakis, M., Alexiou, P., Papadopoulos, G. L., Reczko, M., Dalamagas, T., Giannopoulos, G., Goumas, G., Koukis, E., Kourtis, K., Simossis, V. A., et al. (2009) · BMC Bioinformatics · doi:10.1186/1471-2105-10-295 · Cited by 330

MicroRNA-223 regulates Glut4 expression and cardiomyocyte glucose metabolism

Han, L., Buchan, R. J., & Cook, S. A. (2010) · Cardiovascular Research · doi:10.1093/cvr/cvq010 · Cited by 337

The estrogen receptor-α-induced microRNA signature regulates itself and its transcriptional response

Castellano, L., Giamas, G., Jacob, J., Coombes, R. C., Lucchesi, W., Thiruchelvam, P. T. R., Barton, G. R., Jiao, L. R., Wait, R., Waxman, J., et al. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0906947106 · Cited by 336

Prediction of microRNAs Associated with Human Diseases Based on Weighted k Most Similar Neighbors

Xuan, P., Han, K., Guo, M., Guo, Y., Li, J., Ding, J., Liu, Y., Dai, Q., Li, J., Teng, Z., et al. (2013) · PLoS ONE · doi:10.1371/journal.pone.0070204 · Cited by 324

MicroRNAs and cardiac pathology

Latronico, M. V. G., & Condorelli, G. (2009) · Nature Reviews Cardiology · doi:10.1038/nrcardio.2009.56 · Cited by 320

Integrative approaches for predicting microRNA function and prioritizing disease-related microRNA using biological interaction networks

Zeng, X., Zhang, X., & Zou, Q. (2015) · Briefings in Bioinformatics · doi:10.1093/bib/bbv033 · Cited by 325

Lost in translation: an assessment and perspective for computational microRNA target identification

Alexiou, P., Maragkakis, M., Papadopoulos, G. L., Reczko, M., & Hatzigeorgiou, A. G. (2009) · Computer applications in the biosciences · doi:10.1093/bioinformatics/btp565 · Cited by 330

Joint Genome-Wide Profiling of miRNA and mRNA Expression in Alzheimer's Disease Cortex Reveals Altered miRNA Regulation

Nunez-Iglesias, J., Liu, C.-C., Morgan, T. E., Finch, C. E., & Zhou, X. J. (2010) · PLoS ONE · doi:10.1371/journal.pone.0008898 · Cited by 326

miRWalk Database for miRNA–Target Interactions

Dweep, H., Gretz, N., & Sticht, C. (2014) · Methods in molecular biology · doi:10.1007/978-1-4939-1062-5_25 · Cited by 324

MicroRNA-328 Negatively Regulates the Expression of Breast Cancer Resistance Protein (BCRP/ABCG2) in Human Cancer Cells

Pan, Y.-Z., Morris, M. E., & Yu, A. (2009) · Molecular Pharmacology · doi:10.1124/mol.108.054163 · Cited by 311

The Interleukin 13 (IL-13) Pathway in Human Macrophages Is Modulated by MicroRNA-155 via Direct Targeting of Interleukin 13 Receptor α1 (IL13Rα1)

Martínez-Nuñez, R. T., Louafi, F., & Sánchez-Elsner, T. (2010) · Journal of Biological Chemistry · doi:10.1074/jbc.m110.169367 · Cited by 308

Models of human core transcriptional regulatory circuitriesPreprint

Saint‐André, V., Alexander Joel Federation, Lin, C. Y., Abraham, B. J., Reddy, J., Lee, T. I., Bradner, J. E., & Young, R. A. (2016) · Genome Research · doi:10.1101/gr.197590.115 · Cited by 303

Ancient animal microRNAs and the evolution of tissue identity

Christodoulou, F., Raible, F., Tomer, R., Simakov, O., Trachana, K., Klaus, S., Snyman, H., Hannon, G. J., Bork, P., & Arendt, D. (2010) · Nature · doi:10.1038/nature08744 · Cited by 309

Comprehensive discovery of endogenous Argonaute binding sites in Caenorhabditis elegans

Zisoulis, D. G., Lovci, M., Wilbert, M. L., Hutt, K. R., Liang, T. Y., Pasquinelli, A. E., & Yeo, G. W.-M. (2010) · Nature Structural & Molecular Biology · doi:10.1038/nsmb.1745 · Cited by 297

Birth and expression evolution of mammalian microRNA genesPreprint

Meunier, J., Lemoine, F., Soumillon, M., Liechti, A., Weier, M., Guschanski, K., Hu, H., Khaitovich, P., & Kaessmann, H. (2012) · Genome Research · doi:10.1101/gr.140269.112 · Cited by 291

Identification of Restricted Subsets of Mature microRNA Abnormally Expressed in Inactive Colonic Mucosa of Patients with Inflammatory Bowel Disease

Fasseu, M., Tréton, X., Guichard, C., Pédruzzi, E., Cazals-Hatem, D. L., Richard, C., Aparicio, T., Bleiberg-Daniel, F., Soulé, J., Moreau, R., et al. (2010) · PLoS ONE · doi:10.1371/journal.pone.0013160 · Cited by 286

PhenomiR: a knowledgebase for microRNA expression in diseases and biological processes

Ruepp, A., Kowarsch, A., Schmidl, D., Buggenthin, F., Brauner, B., Dunger-Kaltenbach, I., Fobo, G., Frishman, G., Montrone, C., & Theis, F. J. (2010) · Genome biology · doi:10.1186/gb-2010-11-1-r6 · Cited by 285

miRNAs control insulin content in pancreatic β‐cells via downregulation of transcriptional repressors

Melkman‐Zehavi, T., Oren, R., Kredo‐Russo, S., Shapira, T., Mandelbaum, A. D., Rivkin, N., Nir, T., Lennox, K. A., Behlke, M. A., Dor, Y., et al. (2011) · The EMBO Journal · doi:10.1038/emboj.2010.361 · Cited by 280

The common marmoset genome provides insight into primate biology and evolution

Worley, K. C., Rogers, J., Muzny, D. M., Weinstock, G. M., Chandrabose, M. N., Cree, A., Dao, M., Dinh, H. H., Fowler, R. G., Gabisi, R. A., et al. (2014) · Nature Genetics · doi:10.1038/ng.3042 · Cited by 264

Micromarkers: miRNAs in cancer diagnosis and prognosis

Ferracin, M., Veronese, A., & Negrini, M. (2010) · Expert Review of Molecular Diagnostics · doi:10.1586/erm.10.11 · Cited by 269

MicroRNA Polymorphisms: the Future of Pharmacogenomics, Molecular Epidemiology and Individualized Medicine

Mishra, P. J., & Bertino, J. R. (2009) · Pharmacogenomics · doi:10.2217/14622416.10.3.399 · Cited by 265

Impact of microRNA regulation on variation in human gene expressionPreprint

Lü, J., & Clark, A. G. (2012) · Genome Research · doi:10.1101/gr.132514.111 · Cited by 258

MicroRNA-199b-5p Impairs Cancer Stem Cells through Negative Regulation of HES1 in Medulloblastoma

Garzia, L., Andolfo, I., Cusanelli, E., Marino, N., Petrosino, G., Martino, D. D., Esposito, V., Galeone, A., Navas, L., Esposito, S., et al. (2009) · PLoS ONE · doi:10.1371/journal.pone.0004998 · Cited by 254

MicroRNA-21 Exhibits Antiangiogenic Function by Targeting RhoB Expression in Endothelial Cells

Sabatel, C., Malvaux, L., Bovy, N., Deroanne, C., Lambert, V., Gonzalez, M.-L. A., Colige, A., Rakic, J., Noël, A., MARTIAL, J. A., et al. (2011) · PLoS ONE · doi:10.1371/journal.pone.0016979 · Cited by 256

Biological Basis of miRNA Action when Their Targets Are Located in Human Protein Coding Region

Gu, W., Wang, X., Zhai, C., Zhou, T., & Xie, X. (2013) · PLoS ONE · doi:10.1371/journal.pone.0063403 · Cited by 29

Viral microRNA target allows insight into the role of translation in governing microRNA target accessibility

Lin, H.-R., & Ganem, D. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1102033108 · Cited by 42

Target site effects in the RNA interference and microRNA pathways

Obernosterer, G., Tafer, H., & Martı̂nez, J. (2008) · Biochemical Society Transactions · doi:10.1042/bst0361216 · Cited by 25

Predicting kissing interactions in microRNA–target complex and assessment of microRNA activity

Cao, S., & Chen, S. (2012) · Nucleic Acids Research · doi:10.1093/nar/gks052 · Cited by 35

A detailed investigation of accessibilities around target sites of siRNAs and miRNAs

Kiryu, H., Terai, G., Imamura, O., Yoneyama, H., Suzuki, K., & Asai, K. (2011) · Bioinformatics · doi:10.1093/bioinformatics/btr276 · Cited by 64