Integrin CD11b negatively regulates TLR-triggered inflammatory responses by activating Syk and promoting degradation of MyD88 and TRIF via Cbl-b

Toll-Like Receptors

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The family of five: TIR-domain-containing adaptors in Toll-like receptor signalling

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Negative regulation of Toll-like receptor-mediated immune responses

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The E3 ubiquitin ligase Nrdp1 'preferentially' promotes TLR-mediated production of type I interferon

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Fibrinogen in neurological diseases: mechanisms, imaging and therapeutics

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Phagocytosis: Receptors, signal integration, and the cytoskeleton

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Dissecting negative regulation of Toll-like receptor signaling

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T-box transcription factor T-bet, a key player in a unique type of B-cell activation essential for effective viral clearance

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Apolipoprotein C3 induces inflammation and organ damage by alternative inflammasome activation

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Intracellular MHC class II molecules promote TLR-triggered innate immune responses by maintaining activation of the kinase Btk

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Methyltransferase Dnmt3a upregulates HDAC9 to deacetylate the kinase TBK1 for activation of antiviral innate immunity

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Immune Responsive Gene 1 (IRG1) Promotes Endotoxin Tolerance by Increasing A20 Expression in Macrophages through Reactive Oxygen Species

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Restraint of inflammatory signaling by interdependent strata of negative regulatory pathways

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Evidence for Neuroinflammatory and Microglial Changes in the Cerebral Response to Sleep Loss

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Biophysical regulation of macrophages in health and disease

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Rhbdd3 controls autoimmunity by suppressing the production of IL-6 by dendritic cells via K27-linked ubiquitination of the regulator NEMO

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Inhibition of CBLB protects from lethal Candida albicans sepsis

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Mechanosensing in macrophages and dendritic cells in steady-state and disease

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Integrative approach to sporadic Alzheimer’s disease: deficiency of TYROBP in cerebral Aβ amyloidosis mouse normalizes clinical phenotype and complement subnetwork molecular pathology without reducing Aβ burden

Haure-Mirande, J.-V., Wang, M., Audrain, M., Fanutza, T., Kim, S. H., Heja, S., Readhead, B., Dudley, J. T., Blitzer, R. D., Schadt, E. E., et al. (2019) · Molecular Psychiatry · doi:10.1038/s41380-018-0255-6 · Cited by 84

Integrative approach to sporadic Alzheimer’s disease: deficiency of TYROBP in a tauopathy mouse model reduces C1q and normalizes clinical phenotype while increasing spread and state of phosphorylation of tau

Audrain, M., Haure-Mirande, J.-V., Wang, M., Kim, S. H., Fanutza, T., Chakrabarty, P., Fraser, P., St George-Hyslop, P. H., Golde, T. E., Blitzer, R. D., et al. (2019) · Molecular Psychiatry · doi:10.1038/s41380-018-0258-3 · Cited by 68

Decellularized scaffold and its elicited immune response towards the host: The underlying mechanism and means of immunomodulatory modification

Tan, J., Zhang, Q.-Y., Huang, L.-P., Huang, K., & Xie, H.-Q. (2021) · Biomaterials Science · doi:10.1039/d1bm00470k · Cited by 57

Bim Expression Promotes the Clearance of Mononuclear Phagocytes during Choroidal Neovascularization, Mitigating Scar Formation in Mice

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Identification of tumour‐infiltrating myeloid subsets associated with overall survival in lung squamous cell carcinoma

Lu, J., Duan, Y., Liu, P., He, X., Yang, Y., Zhang, R., & Weng, L. (2023) · The Journal of Pathology · doi:10.1002/path.6015 · Cited by 6