Constant replenishment from circulating monocytes maintains the macrophage pool in the intestine of adult mice

Fate Mapping Reveals Origins and Dynamics of Monocytes and Tissue Macrophages under Homeostasis

Yona, S., Kim, K.-W., Wolf, Y., Mildner, A., Varol, D., Breker, M., Strauss-Ayali, D., Viukov, S., Guilliams, M., Misharin, A., et al. (2013) · Immunity · doi:10.1016/j.immuni.2012.12.001 · Cited by 3,245

CCL2 recruits inflammatory monocytes to facilitate breast-tumour metastasis

Qian, B.-Z., Li, J., Zhang, H., Kitamura, T., Zhang, J., Campion, L. R., Kaiser, E. A., Snyder, L. A., & Pollard, J. W. (2011) · Nature · doi:10.1038/nature10138 · Cited by 2,874

Analysis of Fractalkine Receptor CX3CR1 Function by Targeted Deletion and Green Fluorescent Protein Reporter Gene Insertion

Jung, S., Aliberti, J., Graemmel, P., Sunshine, M. J., Kreutzberg, G. W., Sher, A., & Littman, D. R. (2000) · Molecular and Cellular Biology · doi:10.1128/mcb.20.11.4106-4114.2000 · Cited by 2,632

A Lineage of Myeloid Cells Independent of Myb and Hematopoietic Stem Cells

Schulz, C., Perdiguero, E. G., Chorro, L., Szabo-Rogers, H., Cagnard, N., Kierdorf, K., Prinz, M., Wu, B., Jacobsen, S. E. W., Pollard, J. W., et al. (2012) · Science · doi:10.1126/science.1219179 · Cited by 2,578

Tissue-Resident Macrophages Self-Maintain Locally throughout Adult Life with Minimal Contribution from Circulating Monocytes

Hashimoto, D., Chow, A., Noizat, C., Teo, P., Beasley, M. B., Leboeuf, M., Becker, C. D., See, P., Price, J., Lucas, D., et al. (2013) · Immunity · doi:10.1016/j.immuni.2013.04.004 · Cited by 2,311

Tissue-resident macrophages

Davies, L. C., Jenkins, S. J., Allen, J. E., & Taylor, P. R. (2013) · Nature Immunology · doi:10.1038/ni.2705 · Cited by 2,096

Monocyte emigration from bone marrow during bacterial infection requires signals mediated by chemokine receptor CCR2

Serbina, N. V., & Pamer, E. G. (2006) · Nature Immunology · doi:10.1038/ni1309 · Cited by 1,658

Local self-renewal can sustain CNS microglia maintenance and function throughout adult life

Ajami, B., Bennett, J. L., Krieger, C., Tetzlaff, W., & Rossi, F. M. V. (2007) · Nature Neuroscience · doi:10.1038/nn2014 · Cited by 1,643

Origin and functions of tissue macrophages

Epelman, S., Lavine, K. J., & Randolph, G. J. (2014) · Immunity · doi:10.1016/j.immuni.2014.06.013 · Cited by 1,585

Embryonic and Adult-Derived Resident Cardiac Macrophages Are Maintained through Distinct Mechanisms at Steady State and during Inflammation

Epelman, S., Lavine, K. J., Beaudin, A. E., Sojka, D. K., Carrero, J. A., Calderon, B., Brija, T., Gautier, E. L., Ivanov, S., Satpathy, A. T., et al. (2014) · Immunity · doi:10.1016/j.immuni.2013.11.019 · Cited by 1,494

Macrophage immunometabolism in inflammatory bowel diseases: From pathogenesis to therapy

Pan, X., Zhu, Q., Pan, L., & Sun, J. T. (2022) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2022.108176 · Cited by 252

Gut Mycobiota in Immunity and Inflammatory Disease

Li, X. V., Leonardi, I., & Iliev, I. D. (2019) · Immunity · doi:10.1016/j.immuni.2019.05.023 · Cited by 246

Pattern of human monocyte subpopulations in health and disease

Ożańska, A., Szymczak, D., & Rybka, J. (2020) · Scandinavian Journal of Immunology · doi:10.1111/sji.12883 · Cited by 261

Intestinal CD169+ macrophages initiate mucosal inflammation by secreting CCL8 that recruits inflammatory monocytes

Asano, K., Takahashi, N., Ushiki, M., Monya, M., Aihara, F., Kuboki, E., Moriyama, S., Iida, M., Kitamura, H., Qiu, C., et al. (2015) · Nature Communications · doi:10.1038/ncomms8802 · Cited by 240

The impact of microbiota-derived short-chain fatty acids on macrophage activities in disease: Mechanisms and therapeutic potentials

Duan, H., Wang, L., Huangfu, M., & Li, H. (2023) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2023.115276 · Cited by 252

The Interplay Between Monocytes/Macrophages and CD4+ T Cell Subsets in Rheumatoid Arthritis

Roberts, C. A., Dickinson, A. K., & Taams, L. S. (2015) · Frontiers in Immunology · doi:10.3389/fimmu.2015.00571 · Cited by 238

Colonic macrophage polarization in homeostasis, inflammation, and cancer

Isidro, R. A., & Appleyard, C. B. (2016) · American Journal of Physiology-Gastrointestinal and Liver Physiology · doi:10.1152/ajpgi.00123.2016 · Cited by 238

Exposure to Bacterial CpG DNA Protects from Airway Allergic Inflammation by Expanding Regulatory Lung Interstitial Macrophages

Sabatel, C. M., Radermecker, C., Fiévez, L., Paulissen, G., Chakarov, S., Fernandes, C., Olivier, S., Toussaint, M., Pirottin, D., Xiao, X., et al. (2017) · Immunity · doi:10.1016/j.immuni.2017.02.016 · Cited by 244

A Subset of Skin Macrophages Contributes to the Surveillance and Regeneration of Local Nerves

Kolter, J., Feuerstein, R., Zeis, P., Hagemeyer, N., Paterson, N., d’Errico, P., Baasch, S., Amann, L., Masuda, T., Lößlein, A. K., et al. (2019) · Immunity · doi:10.1016/j.immuni.2019.05.009 · Cited by 233

Human Induced Pluripotent Stem Cell-Derived Macrophages Share Ontogeny with MYB-Independent Tissue-Resident Macrophages

Buchrieser, J., James, W., & Moore, M. D. (2017) · Stem Cell Reports · doi:10.1016/j.stemcr.2016.12.020 · Cited by 215

Intestinal Dendritic Cells in Health and Gut Inflammation

Stagg, A. J. (2018) · Frontiers in Immunology · doi:10.3389/fimmu.2018.02883 · Cited by 210

The role of CSF1R-dependent macrophages in control of the intestinal stem-cell niche

Sehgal, A., Donaldson, D. S., Pridans, C., Sauter, K. A. D., Hume, D. A., & Mabbott, N. A. (2018) · Nature Communications · doi:10.1038/s41467-018-03638-6 · Cited by 208

Monocytes in Myocardial Infarction

Dutta, P., & Nahrendorf, M. (2015) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.114.304652 · Cited by 223

The impact of sensory neuropathy and inflammation on epithelial wound healing in diabetic corneas

Yu, F.-S. X., Lee, P. S. Y., Yang, L., Gao, N., Zhang, Y., Ljubimov, A. V., Yang, E., Zhou, Q., & Xie, L. (2022) · Progress in Retinal and Eye Research · doi:10.1016/j.preteyeres.2021.101039 · Cited by 217

Antibiotic-induced gut dysbiosis and barrier disruption and the potential protective strategies

Duan, H., Yu, L., Tian, F., Zhai, Q., Fan, L., & Chen, W. (2020) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2020.1843396 · Cited by 219

Macrophage polarization in inflammatory bowel disease

Zhang, K., Guo, J., Yan, W., & Xu, L. (2023) · Cell Communication and Signaling · doi:10.1186/s12964-023-01386-9 · Cited by 228

Colonic Pro-inflammatory Macrophages Cause Insulin Resistance in an Intestinal Ccl2/Ccr2-Dependent Manner

Kawano, Y., Nakae, J., Watanabe, N., Kikuchi, T., Tateya, S., Tamori, Y., Kaneko, M., Abe, T., Onodera, M., & Itoh, H. (2016) · Cell Metabolism · doi:10.1016/j.cmet.2016.07.009 · Cited by 207

Macrophage-derived IL-10 mediates mucosal repair by epithelial WISP-1 signaling.

Quirós, M., Nishio, H., Neumann, P., Siuda, D., Brazil, J., Azcutia, V., Hilgarth, R., O'Leary, M. N., Garcia-Hernandez, V., Leoni, G., et al. (2017) · Journal of Clinical Investigation · doi:10.1172/jci90229 · Cited by 169

A three-dimensional immunocompetent intestine-on-chip model as in vitro platform for functional and microbial interaction studies

Maurer, M., Gresnigt, M. S., Last, A., Wollny, T., Berlinghof, F., Pospich, R., Cseresnyés, Z., Medyukhina, A., Graf, K., Gröger, M., et al. (2019) · Biomaterials · doi:10.1016/j.biomaterials.2019.119396 · Cited by 209

Critical Role for the Microbiota in CX3CR1+ Intestinal Mononuclear Phagocyte Regulation of Intestinal T Cell Responses

Kim, M., Galan, C., Hill, A. A., Wu, W.-J., Fehlner-Peach, H., Song, H. W., Schady, D., Bettini, M. L., Simpson, K. W., Longman, R. S., et al. (2018) · Immunity · doi:10.1016/j.immuni.2018.05.009 · Cited by 202

Myeloid suppressor cells in cancer and autoimmunity

Sica, A., & Massarotti, M. (2017) · Journal of Autoimmunity · doi:10.1016/j.jaut.2017.07.010 · Cited by 201

Mitochondrial ROS Production Protects the Intestine from Inflammation through Functional M2 Macrophage Polarization

Formentini, L., Santacatterina, F., de Arenas, C. N., Stamatakis, K., Martínez, D. L., Logan, A., Fresno, M., Smits, R., Murphy, M. P., & Cuezva, J. M. (2017) · Cell Reports · doi:10.1016/j.celrep.2017.04.036 · Cited by 202

Monocytes, macrophages, dendritic cells and neutrophils: an update on lifespan kinetics in health and disease

Patel, A. A., Ginhoux, F., & Yona, S. (2021) · Immunology · doi:10.1111/imm.13320 · Cited by 228

Macrophage-based cell therapies: The long and winding road

Lee, S., Kivimäe, S., Dolor, A., & Szoka, F. C. (2016) · Journal of Controlled Release · doi:10.1016/j.jconrel.2016.07.018 · Cited by 198

More Than Suppression: Glucocorticoid Action on Monocytes and Macrophages

Ehrchen, J. M., Roth, J., & Barczyk‐Kahlert, K. (2019) · Frontiers in Immunology · doi:10.3389/fimmu.2019.02028 · Cited by 205

Age-dependent shift in macrophage polarisation causes inflammation-mediated degeneration of enteric nervous system

Becker, L., Nguyen, L., Gill, J., Kulkarni, S., Pasricha, P. J., & Habtezion, A. (2018) · Gut · doi:10.1136/gutjnl-2016-312940 · Cited by 196

The Role of Macrophages in HIV-1 Persistence and Pathogenesis

Kruize, Z., & Kootstra, N. A. (2019) · Frontiers in Microbiology · doi:10.3389/fmicb.2019.02828 · Cited by 205

Cytokines in inflammatory bowel diseases – Update 2020

Leppkes, M., & Neurath, M. F. (2020) · Pharmacological Research · doi:10.1016/j.phrs.2020.104835 · Cited by 194

Neonatal gut microbiome and immunity

Sanidad, K. Z., & Zeng, M. Y. (2020) · Current Opinion in Microbiology · doi:10.1016/j.mib.2020.05.011 · Cited by 205

Macrophages are necessary for epimorphic regeneration in African spiny mice

Simkin, J., Gawriluk, T. R., Gensel, J. C., & Seifert, A. W. (2017) · eLife · doi:10.7554/elife.24623 · Cited by 197

Transcriptional and functional profiling defines human small intestinal macrophage subsets

Bujko, A., Atlasy, N., Landsverk, O. J. B., Richter, L., Yaqub, S., Horneland, R., Øyen, O. M., Aandahl, E. M., Aabakken, L., Stunnenberg, H. G., et al. (2017) · The Journal of Experimental Medicine · doi:10.1084/jem.20170057 · Cited by 188

M2 macrophages in kidney disease: biology, therapies, and perspectives

Chen, T., Cao, Q., Wang, Y., & Harris, D. C. H. (2019) · Kidney International · doi:10.1016/j.kint.2018.10.041 · Cited by 190

Editorial: Alveolar Macrophages in Lung Inflammation and Resolution

Hu, G., & Christman, J. W. (2019) · Frontiers in Immunology · doi:10.3389/fimmu.2019.02275 · Cited by 189

Cellular and Molecular Therapeutic Targets in Inflammatory Bowel Disease—Focusing on Intestinal Barrier Function

Schoultz, I., & Keita, Å. V. (2019) · Cells · doi:10.3390/cells8020193 · Cited by 193

Diversity of Intestinal Macrophages in Inflammatory Bowel Diseases

Kühl, A. A., Erben, U., Kredel, L. I., & Siegmund, B. (2015) · Frontiers in Immunology · doi:10.3389/fimmu.2015.00613 · Cited by 191

Orally Targeted Delivery of Tripeptide KPV via Hyaluronic Acid-Functionalized Nanoparticles Efficiently Alleviates Ulcerative Colitis

Xiao, B., Xu, Z., Viennois, É., Zhang, Y., Zhang, Z., Zhang, M., Han, M. K., Kang, Y., & Merlin, D. (2017) · Molecular Therapy · doi:10.1016/j.ymthe.2016.11.020 · Cited by 185

Development of conventional dendritic cells: from common bone marrow progenitors to multiple subsets in peripheral tissues

Sichien, D., Lambrecht, B. N., Guilliams, M., & Scott, C. L. (2017) · Mucosal Immunology · doi:10.1038/mi.2017.8 · Cited by 181

The Good and the Bad: Monocytes’ and Macrophages’ Diverse Functions in Inflammation

Austermann, J., Roth, J., & Barczyk‐Kahlert, K. (2022) · Cells · doi:10.3390/cells11121979 · Cited by 210

Long-term implant fibrosis prevention in rodents and non-human primates using crystallized drug formulations

Farah, S., Doloff, J. C., Müller, P., Sadraei, A., Han, H. J., Olafson, K., Vyas, K., Tam, H. H., Hollister-Lock, J., Kowalski, P. S., et al. (2019) · Nature Materials · doi:10.1038/s41563-019-0377-5 · Cited by 181

Role of Monocytes and Intestinal Macrophages in Crohnʼs Disease and Ulcerative Colitis

Gren, S. T., & Grip, O. (2016) · Inflammatory Bowel Diseases · doi:10.1097/mib.0000000000000824 · Cited by 182

Developmental origin and maintenance of distinct testicular macrophage populations

Mossadegh‐Keller, N., Gentek, R., Gimenez, G., Bigot, S., Mailfert, S., & Sieweke, M. H. (2017) · The Journal of Experimental Medicine · doi:10.1084/jem.20170829 · Cited by 194

Ontogeny of Tumor-Associated Macrophages and Its Implication in Cancer Regulation

Franklin, R. A., & Li, M. O. (2016) · Trends in cancer · doi:10.1016/j.trecan.2015.11.004 · Cited by 179

Unveiling skin macrophage dynamics explains both tattoo persistence and strenuous removal

Barańska, A., Shawket, A., Jouve, M. J., Baratin, M., Malosse, C., Voluzan, O., Manh, T. V., FIORE, F., Bajénoff, M., Benaroch, P., et al. (2018) · The Journal of Experimental Medicine · doi:10.1084/jem.20171608 · Cited by 176

Early hematopoiesis and macrophage development

McGrath, K. E., Frame, J. M., & Palis, J. (2015) · Seminars in Immunology · doi:10.1016/j.smim.2016.03.013 · Cited by 172

Macrophage activation and polarization in post-infarction cardiac remodeling

Энхэевна, Г. А., Rogovskaya, Y. V., Сергеевич, Ш. В., Ребенкова, М. С., Kzhyshkowska, J. G., Popov, S. V., Karpov, R. S., & Ryabov, V. V. (2017) · Journal of Biomedical Science · doi:10.1186/s12929-017-0322-3 · Cited by 180

Emerging role of targeting macrophages in rheumatoid arthritis: Focus on polarization, metabolism and apoptosis

Yang, X., Chang, Y., & Wei, W. (2020) · Cell Proliferation · doi:10.1111/cpr.12854 · Cited by 176

Tissue-resident macrophages: guardians of organ homeostasis

Nobs, S. P., & Köpf, M. (2021) · Trends in Immunology · doi:10.1016/j.it.2021.04.007 · Cited by 180

Macrophages in the gut: Masters in multitasking

Delfini, M., Stakenborg, N., Viola, M. F., & Boeckxstaens, G. E. (2022) · Immunity · doi:10.1016/j.immuni.2022.08.005 · Cited by 182

Diversity and functions of intestinal mononuclear phagocytes

Joeris, T., Müller-Luda, K., Agace, W. W., & Mowat, A. M. (2017) · Mucosal Immunology · doi:10.1038/mi.2017.22 · Cited by 170

Colony-Stimulating Factor 1 Receptor Blockade Inhibits Tumor Growth by Altering the Polarization of Tumor-Associated Macrophages in Hepatocellular Carcinoma

Ao, J., Zhu, X., Chai, Z., Cai, H., Zhang, Y., Zhang, K., Kong, L., Zhang, N., Ye, B., Ma, D.-N., et al. (2017) · Molecular Cancer Therapeutics · doi:10.1158/1535-7163.mct-16-0866 · Cited by 173

Lung Interstitial Macrophages: Past, Present, and Future

Schyns, J., Bureau, F., & Marichal, T. (2018) · Journal of Immunology Research · doi:10.1155/2018/5160794 · Cited by 166

Niche signals and transcription factors involved in tissue-resident macrophage development

T’Jonck, W., Guilliams, M., & Bonnardel, J. (2018) · Cellular Immunology · doi:10.1016/j.cellimm.2018.02.005 · Cited by 173

Neonatal mucosal immunology

Torow, N., Marsland, B. J., Hornef, M. W., & Gollwitzer, E. S. (2016) · Mucosal Immunology · doi:10.1038/mi.2016.81 · Cited by 165

Origins, Biology, and Diseases of Tissue Macrophages

Cox, N., Pokrovskii, M. V., Vicario, R., & Geissmann, F. (2021) · Annual Review of Immunology · doi:10.1146/annurev-immunol-093019-111748 · Cited by 171

Regulation of Embryonic and Postnatal Development by the CSF-1 Receptor

Chiţu, V., & Stanley, E. R. (2016) · Current topics in developmental biology/Current Topics in Developmental Biology · doi:10.1016/bs.ctdb.2016.10.004 · Cited by 163

Gut microbiota derived bile acid metabolites maintain the homeostasis of gut and systemic immunity

Su, L., Gao, Y., & Yang, R. (2023) · Frontiers in Immunology · doi:10.3389/fimmu.2023.1127743 · Cited by 174

Dynamics of Colon Monocyte and Macrophage Activation During Colitis

Jones, G., Bain, C. C., Fenton, T. M., Kelly, A., Brown, S. L., Ivens, A. C., Travis, M. A., Cook, P. C., & MacDonald, A. S. (2018) · Frontiers in Immunology · doi:10.3389/fimmu.2018.02764 · Cited by 162

Cross-talk between the gut microbiota and monocyte-like macrophages mediates an inflammatory response to promote colitis-associated tumourigenesis

Yang, Y., Li, L., Xu, C., Wang, Y., Wang, Z., Chen, M., Zhou, J., Pan, J., Yang, C., Li, X., et al. (2020) · Gut · doi:10.1136/gutjnl-2020-320777 · Cited by 162

Tissue-specific differentiation of colonic macrophages requires TGFβ receptor-mediated signaling

Schridde, A., Bain, C. C., Mayer, J. U., Montgomery, J. P., Pollet, É., Denecke, B., Milling, S. W. F., Jenkins, S. J., Dalod, M., Henri, S., et al. (2017) · Mucosal Immunology · doi:10.1038/mi.2016.142 · Cited by 158

Tissue-Resident Macrophage Development and Function

Wu, Y., & Hirschi, K. K. (2021) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2020.617879 · Cited by 169

Macrophage: Key player in the pathogenesis of autoimmune diseases

Yang, S. C., Zhao, M., & Jia, S. (2023) · Frontiers in Immunology · doi:10.3389/fimmu.2023.1080310 · Cited by 165

Barrier-tissue macrophages: functional adaptation to environmental challenges

Mowat, A. M., Scott, C. L., & Bain, C. C. (2017) · Nature Medicine · doi:10.1038/nm.4430 · Cited by 162

GM-CSF Calibrates Macrophage Defense and Wound Healing Programs during Intestinal Infection and Inflammation

Castro‐Dopico, T., Fleming, A., Dennison, T. W., Ferdinand, J. R., Harcourt, K., Stewart, B. J., Cader, M. Z., Tuong, Z. K., Jing, C., Lok, L. S. C., et al. (2020) · Cell Reports · doi:10.1016/j.celrep.2020.107857 · Cited by 166

Monocyte Regulation in Homeostasis and Malignancy

Robinson, A., Han, C. Z., Glass, C. K., & Pollard, J. W. (2021) · Trends in Immunology · doi:10.1016/j.it.2020.12.001 · Cited by 165

IRF8 Transcription-Factor-Dependent Classical Dendritic Cells Are Essential for Intestinal T Cell Homeostasis

Luda, K. M., Joeris, T., Persson, E. K., Rivollier, A., Demiri, M., Sitnik, K., Pool, L., Holm, J. B., Melo-González, F., Richter, L., et al. (2016) · Immunity · doi:10.1016/j.immuni.2016.02.008 · Cited by 154

Macrophages in gastrointestinal homeostasis and inflammation

Grainger, J. R., Konkel, J. E., Zangerle-Murray, T., & Shaw, T. N. (2017) · Pflügers Archiv - European Journal of Physiology · doi:10.1007/s00424-017-1958-2 · Cited by 157

Human intestinal pro-inflammatory CD11chighCCR2+CX3CR1+ macrophages, but not their tolerogenic CD11c−CCR2−CX3CR1− counterparts, are expanded in inflammatory bowel disease

Bernardo, D., Marín, A. C., Fernández‐Tomé, S., Montalban‐Arques, A., Carrasco, A., Tristán, E., Moreno, L. O., Mora‐Gutiérrez, I., Díaz-Guerra, A., Caminero-Fernández, R., et al. (2018) · Mucosal Immunology · doi:10.1038/s41385-018-0030-7 · Cited by 154

Immune Cell Subtypes and Their Function in the Testis

Bhushan, S., Theas, M. S., Guazzone, V. A., Jacobo, P. V., Wang, M., Fijak, M., Meinhardt, A., & Lustig, L. (2020) · Frontiers in Immunology · doi:10.3389/fimmu.2020.583304 · Cited by 153

A common framework of monocyte-derived macrophage activation

Sanin, D. E., Ge, Y., Marinković, E., Kabat, A. M., Castoldi, Â., Caputa, G., Grzes, K. M., Curtis, J. D., Thompson, E. A., Willenborg, S., et al. (2022) · Science Immunology · doi:10.1126/sciimmunol.abl7482 · Cited by 161

Intestinal monocyte-derived macrophages control commensal-specific Th17 responses

Panea, C., Farkas, A. M., Goto, Y., Abdollahi-Roodsaz, S., Lee, C., Koscsó, B., Gowda, K., Hohl, T. M., Bogunovic, M., & Ivanov, I. I. (2015) · Cell Reports · doi:10.1016/j.celrep.2015.07.040 · Cited by 152

Tissue-resident versus monocyte-derived macrophages in the tumor microenvironment

Lahmar, Q., Keirsse, J., Laoui, D., Movahedi, K., Overmeire, E. V., & Ginderachter, J. A. V. (2015) · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer · doi:10.1016/j.bbcan.2015.06.009 · Cited by 161

Monocytes and macrophages in COVID-19: Friends and foes

Meidaninikjeh, S., Sabouni, N., Marzouni, H. Z., Bengar, S., Khalili, A., & Jafari, R. (2021) · Life Sciences · doi:10.1016/j.lfs.2020.119010 · Cited by 156

Monocyte Heterogeneity: Consequences for Monocyte-Derived Immune Cells

Sprangers, S., de Vries, T. J., & Everts, V. E. (2016) · Journal of Immunology Research · doi:10.1155/2016/1475435 · Cited by 164

PTPN2 Regulates Interactions Between Macrophages and Intestinal Epithelial Cells to Promote Intestinal Barrier Function

Spalinger, M. R., Sayoc-Becerra, A., Santos, A. N., Shawki, A., Canale, V., Krishnan, M., Niechcial, A., Obialo, N. M., Scharl, M. M., Li, J., et al. (2020) · Gastroenterology · doi:10.1053/j.gastro.2020.07.004 · Cited by 153

Transcriptome‐based profiling of yolk sac‐derived macrophages reveals a role for Irf8 in macrophage maturation

Hagemeyer, N., Kierdorf, K., Frenzel, K., Xue, J., Ringelhan, M., Abdullah, Z., Godin, I., Wieghofer, P., Jordão, M. J. C., Ulas, T., et al. (2016) · The EMBO Journal · doi:10.15252/embj.201693801 · Cited by 144

Macrophage phenotype and bioenergetics are controlled by oxidized phospholipids identified in lean and obese adipose tissue

Serbulea, V., Upchurch, C. M., Schappe, M. S., Voigt, P. E., DeWeese, D. E., Desai, B. N., Meher, A. K., & Leitinger, N. (2018) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1800544115 · Cited by 151

S100A8 and S100A9 Are Important for Postnatal Development of Gut Microbiota and Immune System in Mice and Infants

Willers, M., Ulas, T., Völlger, L., Vogl, T., Heinemann, A. S., Pirr, S., Pagel, J., Fehlhaber, B., Halle, O., Schöning, J., et al. (2020) · Gastroenterology · doi:10.1053/j.gastro.2020.08.019 · Cited by 145

TNFα gene silencing mediated by orally targeted nanoparticles combined with interleukin-22 for synergistic combination therapy of ulcerative colitis

Xiao, B., Chen, Q., Zhang, Z., Wang, L., Kang, Y., Denning, T. L., & Merlin, D. (2018) · Journal of Controlled Release · doi:10.1016/j.jconrel.2018.08.021 · Cited by 144

Regulation of Innate and Adaptive Immunity by TGFβ

Kelly, A., Houston, S. A., Sherwood, E., Casulli, J., & Travis, M. A. (2017) · Advances in immunology · doi:10.1016/bs.ai.2017.01.001 · Cited by 145

The role of inflammatory cytokines and tumor associated macrophages (TAMs) in microenvironment of pancreatic cancer

Valilou, S. F., Keshavarz‐Fathi, M., Silvestris, N., Argentiero, A., & Rezaei, N. (2018) · Cytokine & Growth Factor Reviews · doi:10.1016/j.cytogfr.2018.01.007 · Cited by 147

Macrophage Biology, Classification, and Phenotype in Cardiovascular Disease

Williams, J. W., Giannarelli, C., Rahman, A. H., Randolph, G. J., & Kovacic, J. C. (2018) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2018.08.2148 · Cited by 149

A myeloid–stromal niche and gp130 rescue in NOD2-driven Crohn’s disease

Nayar, S., Morrison, J. K., Giri, M., Gettler, K., Chuang, L.-S. F., Walker, L. A., Ko, H. M., Kenigsberg, E., Kugathasan, S., Mérad, M., et al. (2021) · Nature · doi:10.1038/s41586-021-03484-5 · Cited by 141

CD11c+ monocyte/macrophages promote chronic Helicobacter hepaticus-induced intestinal inflammation through the production of IL-23

Arnold, I. C., Mathisen, S., Schulthess, J., Danne, C., Hegazy, A. N., & Powrie, F. M. (2015) · Mucosal Immunology · doi:10.1038/mi.2015.65 · Cited by 138

Pleiotropic Impacts of Macrophage and Microglial Deficiency on Development in Rats with Targeted Mutation of the Csf1r Locus

Pridans, C., Raper, A., Davis, G. M., Alves, J., Sauter, K. A. D., Lefèvre, L., Regan, T. W., Meek, S. E., Sutherland, L., Thomson, A. J., et al. (2018) · The Journal of Immunology · doi:10.4049/jimmunol.1701783 · Cited by 139

Renal Sodium Gradient Orchestrates a Dynamic Antibacterial Defense Zone

Berry, M., Mathews, R. J., Ferdinand, J. R., Jing, C., Loudon, K. W., Wlodek, E., Dennison, T. W., Küper, C., Neuhofer, W., & Clatworthy, M. R. (2017) · Cell · doi:10.1016/j.cell.2017.07.022 · Cited by 138

Gut Microbiome and Osteoporosis

Ding, K., Hua, F., & Ding, W. (2020) · Aging and disease · doi:10.14336/ad.2019.0523 · Cited by 134

Human and Mouse Mononuclear Phagocyte Networks: A Tale of Two Species?

Reynolds, G., & Haniffa, M. A. (2015) · Frontiers in Immunology · doi:10.3389/fimmu.2015.00330 · Cited by 138

T Cell Zone Resident Macrophages Silently Dispose of Apoptotic Cells in the Lymph Node

Baratin, M., Simon, L., Jorquera, A., Ghigo, C., Dembélé, D., Nowak, J., Gentek, R., Wienert, S., Klauschen, F., MALISSEN, B., et al. (2017) · Immunity · doi:10.1016/j.immuni.2017.07.019 · Cited by 136

The Role of Intestinal Macrophages in Gastrointestinal Homeostasis: Heterogeneity and Implications in Disease

Yip, J. L. K., Balasuriya, G. K., Spencer, S. J., & Hill‐Yardin, E. L. (2021) · Cellular and Molecular Gastroenterology and Hepatology · doi:10.1016/j.jcmgh.2021.08.021 · Cited by 130

Pattern Recognition Receptor Signaling and Cytokine Networks in Microbial Defenses and Regulation of Intestinal Barriers: Implications for Inflammatory Bowel Disease

Abraham, C., Abreu, M. T., & Turner, J. R. (2022) · Gastroenterology · doi:10.1053/j.gastro.2021.12.288 · Cited by 129

IL-10 produced by macrophages regulates epithelial integrity in the small intestine

Morhardt, T. L., Hayashi, A., Ochi, T., Quirós, M., Kitamoto, S., Nagao‐Kitamoto, H., Kuffa, P., Atarashi, K., Honda, K., Kao, J. Y., et al. (2019) · Scientific Reports · doi:10.1038/s41598-018-38125-x · Cited by 129

Macrophage form, function, and phenotype in mycobacterial infection: lessons from tuberculosis and other diseases

McClean, C. M., & Tobin, D. M. (2016) · Pathogens and Disease · doi:10.1093/femspd/ftw068 · Cited by 135

The influence of environment and origin on brain resident macrophages and implications for therapy

Bennett, M. L., & Bennett, F. C. (2019) · Nature Neuroscience · doi:10.1038/s41593-019-0545-6 · Cited by 136

Differential Location and Distribution of Hepatic Immune Cells

Freitas-Lopes, M., Mafra, K., David, B., Carvalho-Gontijo, R., & Menezes, G. (2017) · Cells · doi:10.3390/cells6040048 · Cited by 126

IgG and Fcγ Receptors in Intestinal Immunity and Inflammation

Castro‐Dopico, T., & Clatworthy, M. R. (2019) · Frontiers in Immunology · doi:10.3389/fimmu.2019.00805 · Cited by 128

Human monocytes and macrophages regulate immune tolerance via integrin αvβ8–mediated TGFβ activation

Kelly, A., Gunaltay, S., McEntee, C. P., Shuttleworth, E. E., Smedley, C., Houston, S. A., Fenton, T. M., Levison, S., Mann, E. R., & Travis, M. A. (2018) · Journal of Experimental Medicine · doi:10.1084/jem.20171491 · Cited by 124

Myocardial infarction: a critical role of macrophages in cardiac remodeling

Weinberger, T., & Schulz, C. (2015) · Frontiers in Physiology · doi:10.3389/fphys.2015.00107 · Cited by 125

A Hitchhiker’s Guide to Myeloid Cell Subsets: Practical Implementation of a Novel Mononuclear Phagocyte Classification System

Guilliams, M., & van de Laar, L. (2015) · Frontiers in Immunology · doi:10.3389/fimmu.2015.00406 · Cited by 135

Human lung-resident macrophages express CB1 and CB2 receptors whose activation inhibits the release of angiogenic and lymphangiogenic factors

Staiano, R. I., Loffredo, S., Borriello, F., Iannotti, F. A., Piscitelli, F., Orlando, P., Secondo, A., Granata, F., Lepore, M. T., Fiorelli, A., et al. (2015) · Journal of Leukocyte Biology · doi:10.1189/jlb.3hi1214-584r · Cited by 126

Macrophages and Dendritic Cells

Cybulsky, M. I., Cheong, C., & Robbins, C. S. (2016) · Circulation Research · doi:10.1161/circresaha.115.306542 · Cited by 130

Gut needs a steady supply of reinforcements

Bordon, Y. (2014) · Nature reviews. Immunology · doi:10.1038/nri3753

Self-Maintaining Gut Macrophages Are Essential for Intestinal Homeostasis

Schepper, S. D., Verheijden, S., Aguilera‐Lizarraga, J., Viola, M. F., Boesmans, W., Stakenborg, N., Voytyuk, I., Schmidt, I., Boeckx, B., de Casterlé, I. D., et al. (2018) · Cell · doi:10.1016/j.cell.2018.07.048 · Cited by 578

The monocyte-macrophage axis in the intestine

Bain, C. C., & Mowat, A. M. (2014) · Cellular Immunology · doi:10.1016/j.cellimm.2014.03.012 · Cited by 167

Macrophages in intestinal homeostasis and inflammation

Bain, C. C., & Mowat, A. M. (2014) · Immunological Reviews · doi:10.1111/imr.12192 · Cited by 615

Tissue-resident macrophages in the intestine are long lived and defined by Tim-4 and CD4 expression

Shaw, T. N., Houston, S. A., Wemyss, K., Bridgeman, H. M., Barbera, T. A., Zangerle-Murray, T., Strangward, P., Ridley, A. J. L., Wang, P., Tamoutounour, S., et al. (2018) · The Journal of Experimental Medicine · doi:10.1084/jem.20180019 · Cited by 395