Interferon-γ regulates cellular metabolism and mRNA translation to potentiate macrophage activation

<tt>edgeR</tt> : a Bioconductor package for differential expression analysis of digital gene expression data

Robinson, M. D., McCarthy, D. J., & Smyth, G. K. (2010) · Bioinformatics · doi:10.1093/bioinformatics/btp616 · Cited by 41,364 · see citing works

mTOR Signaling in Growth Control and Disease

Laplante, M., & Sabatini, D. M. (2012) · Cell · doi:10.1016/j.cell.2012.03.017 · Cited by 8,509 · see citing works

The M1 and M2 paradigm of macrophage activation: Time for reassessment

Martinez, F. O., & Gordon, S. (2014) · F1000Prime Reports · doi:10.12703/p6-13 · Cited by 4,689 · see citing works

Genome-Wide Analysis in Vivo of Translation with Nucleotide Resolution Using Ribosome Profiling

Ingolia, N. T., Ghaemmaghami, S., Newman, J. R. S., & Weissman, J. S. (2009) · Science · doi:10.1126/science.1168978 · Cited by 3,853 · see citing works

Regulation of type I interferon responses

Ivashkiv, L. B., & Donlin, L. T. (2013) · Nature reviews. Immunology · doi:10.1038/nri3581 · Cited by 3,311 · see citing works

A diverse range of gene products are effectors of the type I interferon antiviral response

Schoggins, J. W., Wilson, S. J., Panis, M., Murphy, M. Y., Jones, C. T., Bieniasz, P. D., & Rice, C. M. (2011) · Nature · doi:10.1038/nature09907 · Cited by 2,439 · see citing works

Ido expression by dendritic cells: tolerance and tryptophan catabolism

Mellor, A. L., & Munn, D. H. (2004) · Nature Reviews Immunology · doi:10.1038/nri1457 · Cited by 2,341 · see citing works

mTOR- and HIF-1α–mediated aerobic glycolysis as metabolic basis for trained immunity

Cheng, S.-C., Quintin, J., Cramer, R. A., Shepardson, K. M., Saeed, S., Kumar, V., Giamarellos-Bourboulis, E. J., Martens, J. H. A., Rao, N. A., Aghajanirefah, A., et al. (2014) · Science · doi:10.1126/science.1250684 · Cited by 2,224 · see citing works

Autophagy in infection, inflammation and immunity

Deretic, V., Saitoh, T., & Akira, S. (2013) · Nature Reviews Immunology · doi:10.1038/nri3532 · Cited by 1,919 · see citing works

mTORC1 Senses Lysosomal Amino Acids Through an Inside-Out Mechanism That Requires the Vacuolar H ⁺ -ATPase

Zoncu, R., Bar-Peled, L., Efeyan, A., Wang, S., Sancak, Y., & Sabatini, D. M. (2011) · Science · doi:10.1126/science.1207056 · Cited by 1,673 · see citing works

The JAK-STAT Pathway at Twenty

Stark, G. R., & Darnell, J. E., Jr. (2012) · Immunity · doi:10.1016/j.immuni.2012.03.013 · Cited by 1,523 · see citing works

A unifying model for mTORC1-mediated regulation of mRNA translation

Thoreen, C. C., Chantranupong, L., Keys, H. R., Wang, T., Gray, N. S., & Sabatini, D. M. (2012) · Nature · doi:10.1038/nature11083 · Cited by 1,477 · see citing works

An Epigenetic Switch Involving NF-κB, Lin28, Let-7 MicroRNA, and IL6 Links Inflammation to Cell Transformation

Iliopoulos, D., Hirsch, H. A., & Struhl, K. (2009) · Cell · doi:10.1016/j.cell.2009.10.014 · Cited by 1,374 · see citing works

Amino Acid Sufficiency and mTOR Regulate p70 S6 Kinase and eIF-4E BP1 through a Common Effector Mechanism

Hara, K., Yonezawa, K., Weng, Q.-P., Kozlowski, M. T., BELHAM, C. M., & Avruch, J. (1998) · Journal of Biological Chemistry · doi:10.1074/jbc.273.23.14484 · Cited by 1,370 · see citing works

The translational landscape of mTOR signalling steers cancer initiation and metastasis

Hsieh, A. C., Liu, Y., Edlind, M. P., Ingolia, N. T., Janes, M. R., Sher, A., Shi, E. Y., Stumpf, C. R., Christensen, C., Bonham, M. J., et al. (2012) · Nature · doi:10.1038/nature10912 · Cited by 1,313 · see citing works

The ribosome profiling strategy for monitoring translation in vivo by deep sequencing of ribosome-protected mRNA fragments

Ingolia, N. T., Brar, G. A., Rouskin, S., McGeachy, A. M., & Weissman, J. S. (2012) · Nature Protocols · doi:10.1038/nprot.2012.086 · Cited by 1,240 · see citing works

Metabolism of Inflammation Limited by AMPK and Pseudo-Starvation

O'Neill, L. A. J., & Hardie, D. G. (2013) · Nature · doi:10.1038/nature11862 · Cited by 1,133 · see citing works

Relationship between interferon‐γ, indoleamine 2,3‐dioxygenase, and tryptophan catabolism

Taylor, M. W., & Feng, G. (1991) · The FASEB Journal · doi:10.1096/fasebj.5.11.1907934 · Cited by 1,060 · see citing works

Cross-regulation of Signaling Pathways by Interferon-γ: Implications for Immune Responses and Autoimmune Diseases

Hu, X., & Ivashkiv, L. B. (2009) · Immunity · doi:10.1016/j.immuni.2009.09.002 · Cited by 928 · see citing works

Metabolic regulation of immune responses

Ganeshan, K., & Chawla, A. (2014) · Annual Review of Immunology · doi:10.1146/annurev-immunol-032713-120236 · Cited by 926 · see citing works

Ragulator Is a GEF for the Rag GTPases that Signal Amino Acid Levels to mTORC1

Bar-Peled, L., Schweitzer, L. D., Zoncu, R., & Sabatini, D. M. (2012) · Cell · doi:10.1016/j.cell.2012.07.032 · Cited by 918 · see citing works

Latent Enhancers Activated by Stimulation in Differentiated Cells

Ostuni, R., Piccolo, V., Barozzi, I., Polletti, S., Termanini, A., Bonifacio, S., Curina, A., Prosperini, E., Ghisletti, S., & Natoli, G. (2013) · Cell · doi:10.1016/j.cell.2012.12.018 · Cited by 867 · see citing works

Regulation of Immune Responses by mTOR

Powell, J. D., Pollizzi, K. N., Heikamp, E. B., & Horton, M. R. (2012) · Annual Review of Immunology · doi:10.1146/annurev-immunol-020711-075024 · Cited by 836 · see citing works

Leucyl-tRNA Synthetase Is an Intracellular Leucine Sensor for the mTORC1-Signaling Pathway

Han, J. M., Jeong, S. J., Park, M. C., Kim, G., Kwon, N. H., Kim, H. K., Ha, S. H., Ryu, S. H., & Kim, S. (2012) · Cell · doi:10.1016/j.cell.2012.02.044 · Cited by 824 · see citing works

The TSC-mTOR Signaling Pathway Regulates the Innate Inflammatory Response

Weichhart, T., Costantino, G., Poglitsch, M., Rosner, M., Zeyda, M., Stuhlmeier, K. M., Kolbe, T., Stulnig, T. M., Hörl, W. H., Hengstschläger, M., et al. (2008) · Immunity · doi:10.1016/j.immuni.2008.08.012 · Cited by 801 · see citing works

The TSC-mTOR pathway regulates macrophage polarization

Byles, V., Covarrubias, A. J., Ben‐Sahra, I., Lamming, D. W., Sabatini, D. M., Manning, B. D., & Horng, T. (2013) · Nature Communications · doi:10.1038/ncomms3834 · Cited by 628 · see citing works

Notch–RBP-J signaling regulates the transcription factor IRF8 to promote inflammatory macrophage polarization

Xu, H., Zhu, J., Smith, S. M., Foldi, J., Zhao, B., Chung, A. Y., Outtz, H. H., Kitajewski, J., Shi, C., Weber, S., et al. (2012) · Nature Immunology · doi:10.1038/ni.2304 · Cited by 437 · see citing works

IFN-γ Suppresses IL-10 Production and Synergizes with TLR2 by Regulating GSK3 and CREB/AP-1 Proteins

Hu, X., Paik, P. K., Chen, J., Yarilina, A., Kockeritz, L. K., Lu, T. T., Woodgett, J. R., & Ivashkiv, L. B. (2006) · Immunity · doi:10.1016/j.immuni.2006.02.014 · Cited by 407 · see citing works

Amino Acid Starvation Induced by Invasive Bacterial Pathogens Triggers an Innate Host Defense Program

Tattoli, I., Sorbara, M. T., Vuckovic, D., Ling, A., Soares, F., Carneiro, L. A. M., Yang, C., Emili, A., Philpott, D. J., & Girardin, S. E. (2012) · Cell Host & Microbe · doi:10.1016/j.chom.2012.04.012 · Cited by 367 · see citing works

Synergistic Activation of Inflammatory Cytokine Genes by Interferon-γ-Induced Chromatin Remodeling and Toll-like Receptor Signaling

Qiao, Y., Giannopoulou, E. G., Chan, C. H., Park, S.-H., Gong, S., Chen, J., Hu, X., Elemento, O., & Ivashkiv, L. B. (2013) · Immunity · doi:10.1016/j.immuni.2013.08.009 · Cited by 330 · see citing works

Translational control of the innate immune response through IRF-7

Colina, R., Costa‐Mattioli, M., Dowling, R. J. O., Jaramillo, M., Tai, L., Breitbach, C. J., Martineau, Y., Larsson, O. S., Rong, L., Svitkin, Y. V., et al. (2008) · Nature · doi:10.1038/nature06730 · Cited by 316 · see citing works

Regulation of interferon and Toll‐like receptor signaling during macrophage activation by opposing feedforward and feedback inhibition mechanisms

Hu, X., Chakravarty, S. D., & Ivashkiv, L. B. (2008) · Immunological Reviews · doi:10.1111/j.1600-065x.2008.00707.x · Cited by 303 · see citing works

Integrated Regulation of Toll-like Receptor Responses by Notch and Interferon-γ Pathways

Hu, X., Chung, A. Y., Wu, I., Foldi, J., Chen, J., Ji, J. D., Tateya, T., Kang, Y. J., Han, J., Gessler, M., et al. (2008) · Immunity · doi:10.1016/j.immuni.2008.08.016 · Cited by 263 · see citing works

Translational control of immune responses: from transcripts to translatomes

Piccirillo, C. A., Bjur, E., Topisirović, I., Sonenberg, N., & Larsson, O. S. (2014) · Nature Immunology · doi:10.1038/ni.2891 · Cited by 244 · see citing works

Protein synthesis rate is the predominant regulator of protein expression during differentiation

Kristensen, A. R., Gsponer, J., & Foster, L. J. (2013) · Molecular Systems Biology · doi:10.1038/msb.2013.47 · Cited by 217 · see citing works

Phosphorylation of Eukaryotic Protein Synthesis Initiation Factor 4E at Ser-209

Joshi, B., Cai, A., Keiper, B. D., Minich, W. B., Méndez, R., Beach, C. M., Stȩpiński, J., Stolarski, R., Darżynkiewicz, E., & Rhoads, R. E. (1995) · Journal of Biological Chemistry · doi:10.1074/jbc.270.24.14597 · Cited by 216 · see citing works

The GAIT system: a gatekeeper of inflammatory gene expression

Mukhopadhyay, R., Jia, J., Arif, A., Ray, P. S., & Fox, P. L. (2009) · Trends in Biochemical Sciences · doi:10.1016/j.tibs.2009.03.004 · Cited by 216 · see citing works

Rapamycin unbalances the polarization of human macrophages to M1

Mercalli, A., Calavita, I., Dugnani, E., Citro, A., Cantarelli, E., Nano, R., Melzi, R., Maffi, P., Secchi, A., Sordi, V., et al. (2013) · Immunology · doi:10.1111/imm.12126 · Cited by 189 · see citing works

Inhibition of RANK Expression and Osteoclastogenesis by TLRs and IFN-γ in Human Osteoclast Precursors

Ji, J.-D., Park‐Min, K., Shen, Z., Fajardo, R. J., Goldring, S. R., McHugh, K. P., & Ivashkiv, L. B. (2009) · The Journal of Immunology · doi:10.4049/jimmunol.0900072 · Cited by 158 · see citing works

Host Translation at the Nexus of Infection and Immunity

Mohr, I., & Sonenberg, N. (2012) · Cell Host & Microbe · doi:10.1016/j.chom.2012.09.006 · Cited by 157 · see citing works

Translational control of the activation of transcription factor NF-κB and production of type I interferon by phosphorylation of the translation factor eIF4E

Herdy, B., Jaramillo, M., Svitkin, Y. V., Rosenfeld, A. B., Kobayashi, M., Walsh, D., Alain, T., Sean, P., Robichaud, N., Topisirović, I., et al. (2012) · Nature Immunology · doi:10.1038/ni.2291 · Cited by 130 · see citing works

Human tRNA synthetase catalytic nulls with diverse functions

Lo, W.-S., Gardiner, E. M. M., Xu, Z., Lau, C.-F., Wang, F., Zhou, J. J., Mendlein, J. D., Nangle, L. A., Chiang, K. P., Yang, X., et al. (2014) · Science · doi:10.1126/science.1252943 · Cited by 120 · see citing works

mTOR and GSK-3 shape the CD4+ T-cell stimulatory and differentiation capacity of myeloid DCs after exposure to LPS

Turnquist, H. R., Cardinal, J. S., Macedo, C., Rosborough, B. R., Sumpter, T. L., Geller, D. A., Metes, D., & Thomson, A. W. (2010) · Blood · doi:10.1182/blood-2009-10-251488 · Cited by 112 · see citing works

Pathogen signatures activate a ubiquitination pathway that modulates the function of the metabolic checkpoint kinase mTOR

Ivanov, S. S., & Roy, C. R. (2013) · Nature Immunology · doi:10.1038/ni.2740 · Cited by 101 · see citing works

Interleukin-1 Receptor-associated Kinase 2 Is Critical for Lipopolysaccharide-mediated Post-transcriptional Control

Wan, Y., Xiao, H. Q., Affolter, J. T., Kim, T. W., Bulek, K., Chaudhuri, S., Carlson, D., Hamilton, T. A., Mazumder, B., Stark, G. R., et al. (2009) · Journal of Biological Chemistry · doi:10.1074/jbc.m807822200 · Cited by 89 · see citing works

Translation inhibition and metabolic stress pathways in the host response to bacterial pathogens

Lemaître, B., & Girardin, S. E. (2013) · Nature Reviews Microbiology · doi:10.1038/nrmicro3029 · Cited by 65 · see citing works

Apoptosis resistance downstream of eIF4E: posttranscriptional activation of an anti-apoptotic transcript carrying a consensus hairpin structure

Larsson, O. S., Perlman, D., Fan, D., Reilly, C., Peterson, M., Dahlgren, C., Liang, Z., Li, S., Polunovsky, V. A., Wahlestedt, C., et al. (2006) · Nucleic Acids Research · doi:10.1093/nar/gkl558 · Cited by 64 · see citing works

Glycolytic reprogramming by TLRs in dendritic cells

O'Neill, L. A. J. (2014) · Nature Immunology · doi:10.1038/ni.2852 · Cited by 45 · see citing works

Regulation of Interferon-Dependent mRNA Translation of Target Genes

Kroczyńska, B., Mehrotra, S., Arslan, A. D., Kaur, S., & Platanias, L. C. (2014) · Journal of Interferon & Cytokine Research · doi:10.1089/jir.2013.0148 · Cited by 33 · see citing works

Translating Glycolytic Metabolism to Innate Immunity in Dendritic Cells

Cortese, M., Sinclair, C., & Pulendran, B. (2014) · Cell Metabolism · doi:10.1016/j.cmet.2014.04.012 · Cited by 26 · see citing works

IFNγ: signalling, epigenetics and roles in immunity, metabolism, disease and cancer immunotherapy

Ivashkiv, L. B. (2018) · Nature reviews. Immunology · doi:10.1038/s41577-018-0029-z · Cited by 1,374 · see citing works

α-ketoglutarate orchestrates macrophage activation through metabolic and epigenetic reprogramming

Liu, P.-S., Wang, H., Li, X., Chao, T., Teav, T., Christen, S., Di Conza, G., Cheng, W.-C., Chou, C.-H., Vavakova, M., et al. (2017) · Nature Immunology · doi:10.1038/ni.3796 · Cited by 1,264 · see citing works

Regulatory evolution of innate immunity through co-option of endogenous retroviruses

Chuong, E. B., Elde, N. C., & Feschotte, C. (2016) · Science · doi:10.1126/science.aad5497 · Cited by 1,008 · see citing works

Broad defects in the energy metabolism of leukocytes underlie immunoparalysis in sepsis

Cheng, S.-C., Scicluna, B. P., Arts, R. J. W., Gresnigt, M. S., Lachmandas, E., Giamarellos-Bourboulis, E. J., Kox, M., Manjeri, G. R., Wagenaars, J. A. L., Cremer, O. L., et al. (2016) · Nature Immunology · doi:10.1038/ni.3398 · Cited by 637 · see citing works

Human ADAR1 Prevents Endogenous RNA from Triggering Translational Shutdown

Chung, H., Calis, J. J. A., Wu, X., Sun, T., Yu, Y., Sarbanes, S. L., Dao Thi, V. L., Shilvock, A. R., Hoffmann, H.-H., Rosenberg, B. R., et al. (2018) · Cell · doi:10.1016/j.cell.2017.12.038 · Cited by 538 · see citing works

Macrophages and the Recovery from Acute and Chronic Inflammation

Hamidzadeh, K., Christensen, S. M., Dalby, E., Chandrasekaran, P., & Mosser, D. M. (2016) · Annual Review of Physiology · doi:10.1146/annurev-physiol-022516-034348 · Cited by 439 · see citing works

Tryptophan Metabolism in Inflammaging: From Biomarker to Therapeutic Target

Sorgdrager, F. J. H., Naudé, P. J. W., Kema, I. P., Nollen, E. A. A., & Deyn, P. P. D. (2019) · Frontiers in Immunology · doi:10.3389/fimmu.2019.02565 · Cited by 372 · see citing works

Pattern recognition receptors: function, regulation and therapeutic potential

Chen, R., Zou, J., Chen, J., Zhong, X. Y., Kang, R., & Tang, D. (2025) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-025-02264-1 · Cited by 357 · see citing works

Nanoparticles with ultrasound-induced afterglow luminescence for tumour-specific theranostics

Xu, C., Huang, J., Jiang, Y., He, S., Zhang, C., & Pu, K. (2022) · Nature Biomedical Engineering · doi:10.1038/s41551-022-00978-z · Cited by 275 · see citing works

Natural and synthetic carbohydrate-based vaccine adjuvants and their mechanisms of action

Pifferi, C., Fuentes, R., & Fernández‐Tejada, A. (2021) · Nature Reviews Chemistry · doi:10.1038/s41570-020-00244-3 · Cited by 270 · see citing works

Targeting GM-CSF in inflammatory diseases

Wicks, I. P., & Roberts, A. W. (2015) · Nature Reviews Rheumatology · doi:10.1038/nrrheum.2015.161 · Cited by 261 · see citing works

Glutamine Metabolism in Macrophages: A Novel Target for Obesity/Type 2 Diabetes

Ren, W., Xia, Y., Chen, S., Wu, G., Bazer, F. W., Zhou, B., Tan, B., Zhu, G., Deng, J., & Yin, Y. (2018) · Advances in Nutrition · doi:10.1093/advances/nmy084 · Cited by 251 · see citing works

Genome-wide assessment of differential translations with ribosome profiling data

Xiao, Z., Zou, Q., Liu, Y., & Yang, X. (2016) · Nature Communications · doi:10.1038/ncomms11194 · Cited by 236 · see citing works

The Role of Mitophagy in Innate Immunity

Gkikas, I., Palikaras, K., & Tavernarakis, N. (2018) · Frontiers in Immunology · doi:10.3389/fimmu.2018.01283 · Cited by 244 · see citing works

HIF-1α Is an Essential Mediator of IFN-γ–Dependent Immunity to Mycobacterium tuberculosis

Braverman, J., Sogi, K. M., Benjamin, D. I., Nomura, D. K., & Stanley, S. A. (2016) · The Journal of Immunology · doi:10.4049/jimmunol.1600266 · Cited by 233 · see citing works

How Viral and Intracellular Bacterial Pathogens Reprogram the Metabolism of Host Cells to Allow Their Intracellular Replication

Eisenreich, W., Rudel, T., Heesemann, J., & Goebel, W. (2019) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2019.00042 · Cited by 218 · see citing works

Roles of macrophages on ulcerative colitis and colitis-associated colorectal cancer

Zhang, M., Li, X., Zhang, Q., Yang, J., & Liu, G. (2023) · Frontiers in Immunology · doi:10.3389/fimmu.2023.1103617 · Cited by 201 · see citing works

Interferon-γ Represses M2 Gene Expression in Human Macrophages by Disassembling Enhancers Bound by the Transcription Factor MAF

Kang, K., Park, S. H., Chen, J., Qiao, Y., Giannopoulou, E., Berg, K., Hanidu, A., Li, J., Nabozny, G., Kang, K., et al. (2017) · Immunity · doi:10.1016/j.immuni.2017.07.017 · Cited by 196 · see citing works

RiboDiff: detecting changes of mRNA translation efficiency from ribosome footprints

田中, 義., Karaletsos, T., Drewe, P., Sreedharan, V. T., Kuo, D. C., Singh, K., Wendel, H., & Rätsch, G. (2016) · Bioinformatics · doi:10.1093/bioinformatics/btw585 · Cited by 171 · see citing works

Metabolic programming in dendritic cells tailors immune responses and homeostasis

Møller, S. H., Wang, L., & Ho, P. (2021) · Cellular and Molecular Immunology · doi:10.1038/s41423-021-00753-1 · Cited by 180 · see citing works

Toward a Better Regeneration through Implant‐Mediated Immunomodulation: Harnessing the Immune Responses

Zhang, B., Su, Y., Zhou, J., Zheng, Y., & Zhu, D. (2021) · Advanced Science · doi:10.1002/advs.202100446 · Cited by 176 · see citing works

Mycobacterium tuberculosis limits host glycolysis and IL-1β by restriction of PFK-m via microRNA-21

Hackett, E. E., Charles-Messance, H., O'Leary, S., Gleeson, L. E., Muñoz‐Wolf, N., Case, S., Wedderburn, A., Johnston, D. G. W., Williams, M. A., Smyth, A., et al. (2020) · Cell Reports · doi:10.1016/j.celrep.2019.12.015 · Cited by 152 · see citing works

De novo annotation and characterization of the translatome with ribosome profiling data

Xiao, Z., Huang, R., Xing, X., Chen, Y., Deng, H., & Yang, X. (2018) · Nucleic Acids Research · doi:10.1093/nar/gky179 · Cited by 171 · see citing works

Macrophage-based nanotherapeutic strategies in ulcerative colitis

Zhang, J., Zhao, Y., Hou, T., Zeng, H., Kalambhe, D., Wang, B., Shen, X., & Huang, Y. (2020) · Journal of Controlled Release · doi:10.1016/j.jconrel.2020.01.047 · Cited by 160 · see citing works

A Cap-to-Tail Guide to mRNA Translation Strategies in Virus-Infected Cells

Jan, E., Mohr, I., & Walsh, D. (2016) · Annual Review of Virology · doi:10.1146/annurev-virology-100114-055014 · Cited by 144 · see citing works

Interferon-γ primes macrophages for pathogen ligand-induced killing via a caspase-8 and mitochondrial cell death pathway

Simpson, D. S., Pang, J., Weir, A. L., Kong, I. Y., Fritsch, M., Rashidi, M., Cooney, J. P., Davidson, K. C., Speir, M., Djajawi, T. M., et al. (2022) · Immunity · doi:10.1016/j.immuni.2022.01.003 · Cited by 144 · see citing works

IFN-γ selectively suppresses a subset of TLR4-activated genes and enhancers to potentiate macrophage activation

Kang, K., Bachu, M., Park, S. H., Kang, K., Bae, S., Park‐Min, K., & Ivashkiv, L. B. (2019) · Nature Communications · doi:10.1038/s41467-019-11147-3 · Cited by 139 · see citing works

MicroRNA: Dynamic Regulators of Macrophage Polarization and Plasticity

Self-Fordham, J., Naqvi, A. R., Uttamani, J. R., Kulkarni, V., & Nares, S. (2017) · Frontiers in Immunology · doi:10.3389/fimmu.2017.01062 · Cited by 140 · see citing works

Type I and II Interferons in the Anti-Tumor Immune Response

Fenton, S. E., Saleiro, D., & Platanias, L. C. (2021) · Cancers · doi:10.3390/cancers13051037 · Cited by 138 · see citing works

Dysregulation in IFN-γ signaling and response: the barricade to tumor immunotherapy

Han, J., Wu, M., & Liu, Z. (2023) · Frontiers in Immunology · doi:10.3389/fimmu.2023.1190333 · Cited by 142 · see citing works

Effects of Interferons and Viruses on Metabolism

Fritsch, S. D., & Weichhart, T. (2016) · Frontiers in Immunology · doi:10.3389/fimmu.2016.00630 · Cited by 134 · see citing works

Modulation of Macrophage Immunometabolism: A New Approach to Fight Infections

Gauthier, T., & Chen, W. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.780839 · Cited by 134 · see citing works

Metabolic programming of macrophage functions and pathogens control

Koo, S.-J., & Garg, N. J. (2019) · Redox Biology · doi:10.1016/j.redox.2019.101198 · Cited by 132 · see citing works

Metabolism as a Target for Modulation in Autoimmune Diseases

Huang, N., & Perl, A. (2018) · Trends in Immunology · doi:10.1016/j.it.2018.04.006 · Cited by 128 · see citing works

mTOR-Mediated Regulation of Dendritic Cell Differentiation and Function

Sukhbaatar, N., Hengstschläger, M., & Weichhart, T. (2016) · Trends in Immunology · doi:10.1016/j.it.2016.08.009 · Cited by 131 · see citing works

Dynamic Regulation of a Ribosome Rescue Pathway in Erythroid Cells and Platelets

Mills, E. W., Wangen, J. R., Green, R., & Ingolia, N. T. (2016) · Cell Reports · doi:10.1016/j.celrep.2016.08.088 · Cited by 126 · see citing works

Phosphorylation and Signal Transduction Pathways in Translational ControlPreprint

Proud, C. G. (2018) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a033050 · Cited by 121 · see citing works

SLAMF7 engagement superactivates macrophages in acute and chronic inflammation

Simmons, D. P., Nguyen, H., Gomez-Rivas, E., Jeong, Y., Jonsson, A. H., Chen, A. F., Lange, J. K., Dyer, G. S. M., BLAZAR, P. E., Earp, B. E., et al. (2022) · Science Immunology · doi:10.1126/sciimmunol.abf2846 · Cited by 118 · see citing works

Metabolic regulation of macrophages during tissue repair: insights from skeletal muscle regeneration

Juban, G., & Chazaud, B. (2017) · FEBS Letters · doi:10.1002/1873-3468.12703 · Cited by 103 · see citing works

Comprehensive network map of interferon gamma signaling

Bhat, M. Y., Solanki, H. S., Advani, J., Khan, A. A., Prasad, T. S. K., Gowda, H., Thiyagarajan, S., & Chatterjee, A. (2018) · Journal of Cell Communication and Signaling · doi:10.1007/s12079-018-0486-y · Cited by 113 · see citing works

Targeting the mTOR pathway uncouples the efficacy and toxicity of PD-1 blockade in renal transplantation

Esfahani, K., Al-Aubodah, T.-A., Thebault, P., Lapointe, R., Hudson, M., Johnson, N. A., Baran, D., Bhulaiga, N., Takano, T., Cailhier, J.-F., et al. (2019) · Nature Communications · doi:10.1038/s41467-019-12628-1 · Cited by 109 · see citing works

Regulations of Glycolytic Activities on Macrophages Functions in Tumor and Infectious Inflammation

Yu, Q., Wang, Y., Lin, D., He, Y., Liu, R., Yang, Q., Cao, Y., Wang, Y., Jia, A., Bi, Y., et al. (2020) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2020.00287 · Cited by 100 · see citing works

The microRNA-99 family modulates hepatitis B virus replication by promoting IGF-1R/PI3K/Akt/mTOR/ULK1 signaling-induced autophagy

Lin, Y., Deng, W., Pang, J., Kemper, T., Jing Hua, H. U., Yin, J., Zhang, J., & Lu, M. (2016) · Cellular Microbiology · doi:10.1111/cmi.12709 · Cited by 96 · see citing works

mRNA Delivery System for Targeting Antigen‐Presenting Cells In Vivo

Fornaguera, C., Guerra‐Rebollo, M., Lázaro, M. Á., Castells‐Sala, C., Meca‐Cortés, Ó., Ramos‐Pérez, V., Cascante, A., Rubio, N., Blanco, J., & Borrós, S. (2018) · Advanced Healthcare Materials · doi:10.1002/adhm.201800335 · Cited by 95 · see citing works

Targeting NPM1 Epigenetically Promotes Postinfarction Cardiac Repair by Reprogramming Reparative Macrophage Metabolism

Zhang, S., Zhang, Y., Duan, X., Wang, B., & Zhan, Z. (2024) · Circulation · doi:10.1161/circulationaha.123.065506 · Cited by 94 · see citing works

The Regulatory Role of α-Ketoglutarate Metabolism in Macrophages

Liu, S., Yang, J., & Wu, Z.-F. (2021) · Mediators of Inflammation · doi:10.1155/2021/5577577 · Cited by 79 · see citing works

The transcriptional repressor Hes1 attenuates inflammation by regulating transcription elongation

Shang, Y., Coppo, M., He, T., Ning, F., Yu, L., Kang, L., Zhang, B., Ju, C., Qiao, Y., Zhao, B., et al. (2016) · Nature Immunology · doi:10.1038/ni.3486 · Cited by 91 · see citing works

M1 Macrophage Polarization Is Dependent on TRPC1-Mediated Calcium Entry

Chauhan, A., Sun, Y., Sukumaran, P., Zangbede, F. O. Q., Jondle, C. N., Sharma, A., Evans, D. L., Chauhan, P., Szlabick, R. E., Aaland, M. O., et al. (2018) · iScience · doi:10.1016/j.isci.2018.09.014 · Cited by 91 · see citing works

Natural killer cell-intrinsic type I IFN signaling controls Klebsiella pneumoniae growth during lung infection

Ivin, M., Dumigan, A., Vasconcelos, F., Ebner, F., Borroni, M., Kavirayani, A. M., Przybyszewska, K., Ingram, R. J., Lienenklaus, S., Kalinke, U., et al. (2017) · PLoS Pathogens · doi:10.1371/journal.ppat.1006696 · Cited by 85 · see citing works

A Clinical Indications Prediction Scale Based on TWIST1 for Human Mesenchymal Stem Cells

Boregowda, S. V., Krishnappa, V., Haga, C. L., Ortiz, L. A., & Phinney, D. G. (2015) · EBioMedicine · doi:10.1016/j.ebiom.2015.12.020 · Cited by 87 · see citing works

Breast Cancer Induces Systemic Immune Changes on Cytokine Signaling in Peripheral Blood Monocytes and Lymphocytes

Wang, L., Simons, D. L., Lu, X., Tu, T. Y., Avalos, C., Chang, A. Y., Dirbas, F. M., Yim, J. H., Waisman, J., & Lee, P. P. (2020) · EBioMedicine · doi:10.1016/j.ebiom.2020.102631 · Cited by 82 · see citing works

Integration of glucose and cardiolipin anabolism confers radiation resistance of HCC

Fang, Y., Zhan, Y., Xie, Y., Du, S., Chen, Y., Zeng, Z., Zhang, Y., Chen, K., Wang, Y., Li, L., et al. (2021) · Hepatology · doi:10.1002/hep.32177 · Cited by 86 · see citing works

Infectious Triggers in Periodontitis and the Gut in Rheumatoid Arthritis (RA): A Complex Story About Association and Causality

Möller, B., Kollert, F., Sculean, A., & Villiger, P. M. (2020) · Frontiers in Immunology · doi:10.3389/fimmu.2020.01108 · Cited by 82 · see citing works

Regulatory T cells shield muscle mitochondria from interferon-γ–mediated damage to promote the beneficial effects of exercise

Langston, P. K., Sun, Y., Ryback, B. A., Mueller, A. L., Spiegelman, B. M., Benoist, C. O., & Mathis, D. J. (2023) · Science Immunology · doi:10.1126/sciimmunol.adi5377 · Cited by 82 · see citing works

Induction of tumor cell autosis by myxoma virus-infected CAR-T and TCR-T cells to overcome primary and acquired resistance

Zheng, N., Fang, J., Xue, G., Wang, Z., Li, X., Zhou, M., Jin, G., Rahman, M. M., McFadden, G., & Lu, Y. (2022) · Cancer Cell · doi:10.1016/j.ccell.2022.08.001 · Cited by 79 · see citing works

miR-223 Exerts Translational Control of Proatherogenic Genes in Macrophages

Nguyen, M.-A., Hoang, H., Rasheed, A., Duchez, A., Wyatt, H., Cottee, M. L., Graber, T. E., Susser, L., Robichaud, S., Berber, I., et al. (2022) · Circulation Research · doi:10.1161/circresaha.121.319120 · Cited by 76 · see citing works

IFN-γ immune priming of macrophages in vivo induces prolonged STAT1 binding and protection against Cryptococcus neoformans

Wager, C. M. L., Hole, C. R., Campuzano, A., Castro-Lopez, N., Cai, H., Dyke, M. C. C. V., Wozniak, K. L., Wang, Y., & Wormley, F. L. (2018) · PLoS Pathogens · doi:10.1371/journal.ppat.1007358 · Cited by 76 · see citing works

Enhanced translation expands the endo-lysosome size and promotes antigen presentation during phagocyte activation

Hipolito, V. E. B., Diaz, J. A., Tandoc, K. V., Oertlin, C., Ristau, J., Chauhan, N., Sarić, A., McLaughlan, S., Larsson, O. S., Topisirović, I., et al. (2019) · PLoS Biology · doi:10.1371/journal.pbio.3000535 · Cited by 72 · see citing works

Metabolic reprogramming & inflammation: Fuelling the host response to pathogens

Gleeson, L. E., & Sheedy, F. J. (2016) · Seminars in Immunology · doi:10.1016/j.smim.2016.10.007 · Cited by 74 · see citing works

Neuronal Regulation of eIF2α Function in Health and Neurological Disorders

Moon, S. L., Sonenberg, N., & Parker, R. (2018) · Trends in Molecular Medicine · doi:10.1016/j.molmed.2018.04.001 · Cited by 74 · see citing works

Better Living through Chemistry: Caloric Restriction (CR) and CR Mimetics Alter Genome Function to Promote Increased Health and Lifespan

Gillespie, Z. E., Pickering, J., & Eskiw, C. H. (2016) · Frontiers in Genetics · doi:10.3389/fgene.2016.00142 · Cited by 73 · see citing works

Innate Immune Modulation by GM-CSF and IL-3 in Health and Disease

Borriello, F., Galdiero, M., Varricchi, G., Loffredo, S., Spadaro, G., & Marone, G. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms20040834 · Cited by 60 · see citing works

Interferon signaling in cancer. Non-canonical pathways and control of intracellular immune checkpoints

Saleiro, D., & Platanias, L. C. (2019) · Seminars in Immunology · doi:10.1016/j.smim.2019.101299 · Cited by 72 · see citing works

GWIPS-viz: 2018 update

Michel, A. M., Kiniry, S. J., O’Connor, P. B. F., Mullan, J. P. A., & Baranov, P. V. (2017) · Nucleic Acids Research · doi:10.1093/nar/gkx790 · Cited by 70 · see citing works

ROS-associated immune response and metabolism: a mechanistic approach with implication of various diseases

Banerjee, S., Ghosh, S., Mandal, A., Ghosh, N., & Sil, P. (2020) · Archives of Toxicology · doi:10.1007/s00204-020-02801-7 · Cited by 66 · see citing works

TLR-Mediated Innate Production of IFN-γ by CD8+ T Cells Is Independent of Glycolysis

Salerno, F., Guislain, A., Cansever, D., & Wolkers, M. C. (2016) · The Journal of Immunology · doi:10.4049/jimmunol.1501997 · Cited by 73 · see citing works

High-Resolution Mapping and Dynamics of the Transcriptome, Transcription Factors, and Transcription Co-Factor Networks in Classically and Alternatively Activated Macrophages

Das, A., Yang, C.-S., Arifuzzaman, S., Kim, S., Kim, S. Y., Jung, K., Lee, Y.-S., & Chai, Y. (2018) · Frontiers in Immunology · doi:10.3389/fimmu.2018.00022 · Cited by 67 · see citing works

Type II but Not Type I IFN Signaling Is Indispensable for TLR7-Promoted Development of Autoreactive B Cells and Systemic Autoimmunity

Chodisetti, S. B., Fike, A. J., Domeier, P. P., Singh, H., Choi, N. M., Corradetti, C., Kawasawa, Y. I., Cooper, T. K., Caricchio, R., & Rahman, Z. S. M. (2020) · The Journal of Immunology · doi:10.4049/jimmunol.1901175 · Cited by 71 · see citing works

The role of CSDE1 in translational reprogramming and human diseases

Guo, A.-X., Cui, J., Wang, L., & Yin, J. (2020) · Cell Communication and Signaling · doi:10.1186/s12964-019-0496-2 · Cited by 70 · see citing works

Insights into teleost interferon-gamma biology: An update

Pereiro, P., Figueras, A. J., & Novoa, B. (2019) · Fish & Shellfish Immunology · doi:10.1016/j.fsi.2019.04.002 · Cited by 69 · see citing works

A Stat1 bound enhancer promotes Nampt expression and function within tumor associated macrophages

Huffaker, T. B., Ekiz, H. A., Barba, C., Lee, S.-H., Runtsch, M. C., Nelson, M. C., Bauer, K. M., Tang, W. W., Mosbruger, T. L., Cox, J. E., et al. (2021) · Nature Communications · doi:10.1038/s41467-021-22923-5 · Cited by 69 · see citing works

Vaginal epithelial dysfunction is mediated by the microbiome, metabolome, and mTOR signaling

Berard, A. R., Brubaker, D. K., Birse, K., Lamont, A., Mackelprang, R. D., Noël‐Romas, L., Perner, M., Hou, X., Irungu, E., Mugo, N., et al. (2023) · Cell Reports · doi:10.1016/j.celrep.2023.112474 · Cited by 68 · see citing works

Regulation and repurposing of nutrient sensing and autophagy in innate immunity

Sanchez‐Garrido, J., & Shenoy, A. R. (2020) · Autophagy · doi:10.1080/15548627.2020.1783119 · Cited by 66 · see citing works

Neuregulin-1 elicits a regulatory immune response following traumatic spinal cord injury

Alizadeh, A., Santhosh, K. T., Kataria, H., GOUNNI, A. S., & Karimi‐Abdolrezaee, S. (2018) · Journal of Neuroinflammation · doi:10.1186/s12974-018-1093-9 · Cited by 66 · see citing works

GM-CSF and IL-3 Modulate Human Monocyte TNF-α Production and Renewal in In Vitro Models of Trained Immunity

Borriello, F., Iannone, R., Somma, S. D., Loffredo, S., Scamardella, E., Galdiero, M. R., Varricchi, G., Granata, F., Portella, G., & Marone, G. (2017) · Frontiers in Immunology · doi:10.3389/fimmu.2016.00680 · Cited by 65 · see citing works

Sex differences in abdominal aortic aneurysms

Boese, A. C., Chang, L., Yin, K., Chen, Y. E., Lee, J., & Hamblin, M. H. (2018) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00519.2017 · Cited by 65 · see citing works

MicroRNA regulation of macrophages in human pathologies

Wei, Y., & Schober, A. (2016) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-016-2254-6 · Cited by 63 · see citing works

Network models of primary melanoma microenvironments identify key melanoma regulators underlying prognosis

Song, W.-M., Agrawal, P., Von Itter, R., Fontanals-Cirera, B., Wang, M., Zhou, X., Mahal, L. K., Hernando, E., & Zhang, B. (2021) · Nature Communications · doi:10.1038/s41467-021-21457-0 · Cited by 62 · see citing works

The interplay of type I and type II interferons in murine autoimmune cholangitis as a basis for sex‐biased autoimmunity

Bae, H. R., Hodge, D. L., Yang, G., Leung, P. S. C., Chodisetti, S. B., Valencia, J. C., Sanford, M. E., Fenimore, J. M., Rahman, Z. S. M., Tsuneyama, K., et al. (2017) · Hepatology · doi:10.1002/hep.29524 · Cited by 60 · see citing works

Progress in developing MNK inhibitors

Jin, X., Yu, R., Wang, X., Proud, C. G., & Jiang, T. (2021) · European Journal of Medicinal Chemistry · doi:10.1016/j.ejmech.2021.113420 · Cited by 59 · see citing works

Single-Cell RNA Sequencing Reveals Cellular and Transcriptional Changes Associated With M1 Macrophage Polarization in Hidradenitis Suppurativa

Mariottoni, P. R. C. G. B., Jiang, S. W., Prestwood, C. A., Jain, V., Suwanpradid, J., Whitley, M. J., Coates, M., Brown, D. A., Erdmann, D., Corcoran, D. L., et al. (2021) · Frontiers in Medicine · doi:10.3389/fmed.2021.665873 · Cited by 56 · see citing works

Molecular Mechanism of the Anti-Inflammatory Action of Heparin

Litov, L., Petkov, P., Rangelov, M. A., Ilieva, N., Lilkova, E., Todorova, N. H., Krachmarova, E., Malinova, K., Gospodinov, A. G., Hristova, R. H., et al. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms221910730 · Cited by 58 · see citing works

Mitochondrial respiration contributes to the interferon gamma response in antigen-presenting cells

Kiritsy, M. C., McCann, K. J., Mott, D., Holland, S. M., Behar, S. M., Sassetti, C. M., & Olive, A. J. (2021) · eLife · doi:10.7554/elife.65109 · Cited by 56 · see citing works

The transcriptional coregulator GRIP1 controls macrophage polarization and metabolic homeostasis

Coppo, M., Chinenov, Y. V., Sacta, M. A., & Rogatsky, I. (2016) · Nature Communications · doi:10.1038/ncomms12254 · Cited by 55 · see citing works

Pharmacological Manipulation of Translation as a Therapeutic Target for Chronic Pain

Yousuf, M. S., Shiers, S. I., Sahn, J. J., & Price, T. J. (2020) · Pharmacological Reviews · doi:10.1124/pharmrev.120.000030 · Cited by 55 · see citing works

Effects of Lactobacillus plantarum CJLP55 on Clinical Improvement, Skin Condition and Urine Bacterial Extracellular Vesicles in Patients with Acne Vulgaris: A Randomized, Double-Blind, Placebo-Controlled Study

Kim, M.-J., Kim, K.-P., Choi, E., Yim, J.-H., Choi, C., Yun, H.-S., Ahn, H.-Y., Oh, J.-Y., & Cho, Y. (2021) · Nutrients · doi:10.3390/nu13041368 · Cited by 56 · see citing works

Mycobacterium tuberculosis subverts negative regulatory pathways in human macrophages to drive immunopathology

Brace, P., Tezera, L. B., Bielecka, M. K., Mellows, T., Garay‐Baquero, D. J., Tian, S., Rand, L., Green, J. A., Jogai, S., Steele, A. J., et al. (2017) · PLoS Pathogens · doi:10.1371/journal.ppat.1006367 · Cited by 53 · see citing works

De novo histidine biosynthesis protects Mycobacterium tuberculosis from host IFN-γ mediated histidine starvation

Dwivedy, A., Ashraf, A., Jha, B., Kumar, D., Agarwal, N., & Biswal, B. K. (2021) · Communications Biology · doi:10.1038/s42003-021-01926-4 · Cited by 53 · see citing works

Control of T Cell Metabolism by Cytokines and Hormones

Bishop, E. L., Gudgeon, N. H., & Dimeloe, S. (2021) · Frontiers in Immunology · doi:10.3389/fimmu.2021.653605 · Cited by 53 · see citing works

No recovery of replication-competent HIV-1 from human liver macrophages

Kandathil, A. J., Sugawara, S., Goyal, A., Durand, C. M., Quinn, J., Sachithanandham, J., Cameron, A. M., Bailey, J. R., Perelson, A. S., & Balagopal, A. (2018) · Journal of Clinical Investigation · doi:10.1172/jci121678 · Cited by 52 · see citing works

Signaling Crosstalk Mechanisms That May Fine-Tune Pathogen-Responsive NFκB

Adelaja, A., & Hoffmann, A. (2019) · Frontiers in Immunology · doi:10.3389/fimmu.2019.00433 · Cited by 53 · see citing works

Exploiting NK Cell Surveillance Pathways for Cancer Therapy

Barrow, A. D., & Colonna, M. (2019) · Cancers · doi:10.3390/cancers11010055 · Cited by 49 · see citing works

Biomarkers for Chimeric Antigen Receptor T Cell Therapy in Acute Lymphoblastic Leukemia: Prospects for Personalized Management and Prognostic Prediction

Hong, R., Hu, Y., & Huang, H. (2021) · Frontiers in Immunology · doi:10.3389/fimmu.2021.627764 · Cited by 52 · see citing works

The ATPase hCINAP regulates 18S rRNA processing and is essential for embryogenesis and tumour growth

Bai, D., Zhang, J., Li, T., Hang, R., Liu, Y., Tian, Y., Huang, D., Qu, L., Cao, X., Ji, J., et al. (2016) · Nature Communications · doi:10.1038/ncomms12310 · Cited by 50 · see citing works

Interplay between Cellular Metabolism and Cytokine Responses during Viral Infection

Zhang, S., Carrière, J., Lin, X., Xie, N., & Feng, P. (2018) · Viruses · doi:10.3390/v10100521 · Cited by 50 · see citing works

Droplet encapsulation improves accuracy of immune cell cytokine capture assays

Yuan, Y., Brouchon, J., Calvo‐Calle, J. M., Xia, J., Sun, L., Zhang, X., Clayton, K., Ye, F., Weitz, D. A., & Heyman, J. A. (2020) · Lab on a Chip · doi:10.1039/c9lc01261c · Cited by 48 · see citing works

Mitochondrial Regulation of Macrophage Response Against Pathogens

Choudhuri, S., Chowdhury, I. H., & Garg, N. J. (2021) · Frontiers in Immunology · doi:10.3389/fimmu.2020.622602 · Cited by 47 · see citing works

Scikit-ribo Enables Accurate Estimation and Robust Modeling of Translation Dynamics at Codon Resolution

Fang, H., Huang, Y.-F., Radhakrishnan, A., Siepel, A. C., Lyon, G. J., & Schatz, M. C. (2018) · Cell Systems · doi:10.1016/j.cels.2017.12.007 · Cited by 48 · see citing works

Ribosome elongating footprints denoised by wavelet transform comprehensively characterize dynamic cellular translation events

Xu, Z., Hu, L., Shi, B., Geng, S., Xu, L., Wang, D., & Lu, Z. J. (2018) · Nucleic Acids Research · doi:10.1093/nar/gky533 · Cited by 45 · see citing works

Inflammation driven metabolic regulation and adaptation in macrophages

Gupta, S., & Sarangi, P. P. (2022) · Clinical Immunology · doi:10.1016/j.clim.2022.109216 · Cited by 45 · see citing works

Interferon Gamma Induces Reversible Metabolic Reprogramming of M1 Macrophages to Sustain Cell Viability and Pro-Inflammatory Activity

Wang, F., Zhang, S., Jeon, R., Vuckovic, I., Jiang, X., Lerman, A., Folmes, C. D., Dzeja, P. D., & Herrmann, J. (2018) · eBioMedicine · doi:10.1016/j.ebiom.2018.02.009 · Cited by 339 · see citing works

Transcriptional Profiling Suggests Extensive Metabolic Rewiring of Human and Mouse Macrophages during Early Interferon Alpha Responses

Ahmed, D., Jaworski, A. F., Roy, D., Willmore, W. G., Golshani, A., & Cassol, E. (2018) · Mediators of Inflammation · doi:10.1155/2018/5906819 · Cited by 15 · see citing works

Translational Regulation of Specific mRNAs Controls Feedback Inhibition and Survival during Macrophage Activation

Schott, J., Reitter, S., Philipp, J., Haneke, K., Schäfer, H., & Stoecklin, G. (2014) · PLoS Genetics · doi:10.1371/journal.pgen.1004368 · Cited by 136 · see citing works

Gene Regulation in Macrophage Activation: Differential Regulation of Genes Encoding for Tumor Necrosis Factor, Interleukin-1, JE, and KC by interferon-γ and Lipopolysaccharide

Yu, S. F., Koerner, T. J., & Adams, D. O. (1990) · Journal of Leukocyte Biology · doi:10.1002/jlb.48.5.412 · Cited by 64 · see citing works

Pioneer factor IRF1 unlocks latent enhancers to rewire chromatin and immunometabolism in inflammatory macrophagesPreprint

Ayala, J.-M., Bellworthy, R., Mancini, M., Ibarra‐Meneses, A. V., Fernandez‐Prada, C., & Langlais, D. (2026) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.64898/2026.02.27.708404