Natural selection of tumor variants in the generation of “tumor escape” phenotypes

Tumor-associated B7-H1 promotes T-cell apoptosis: A potential mechanism of immune evasion

Dong, H., Strome, S. E., Salomao, D. R., Tamura, H., Hirano, F., Flies, D. B., Roche, P. C., Lu, J., Zhu, G., Tamada, K., et al. (2002) · Nature Medicine · doi:10.1038/nm730 · Cited by 5,025 · see citing works

Activation of NK Cells and T Cells by NKG2D, a Receptor for Stress-Inducible MICA

Bauer, S., Groh, V., Wu, J., Steinle, A., Phillips, J. H., Lanier, L. L., & Spies, T. A. (1999) · Science · doi:10.1126/science.285.5428.727 · Cited by 3,000 · see citing works

IFNγ and lymphocytes prevent primary tumour development and shape tumour immunogenicity

Shankaran, V., Ikeda, H., Bruce, A. T., White, J. M., Swanson, P. E., Old, L. J., & Schreiber, R. D. (2001) · Nature · doi:10.1038/35074122 · Cited by 2,896 · see citing works

Inhibition of death receptor signals by cellular FLIP

Irmler, M., Thome, M., Hahne, M., Schneider, P., Hofmann, K., Steiner, V., Bodmer, J.-L., Schröter, M., Burns, K., Mattmann, C., et al. (1997) · Nature · doi:10.1038/40657 · Cited by 2,548 · see citing works

A cell culture model for T lymphocyte clonal anergy

Schwartz, R. H. (1990) · Science · doi:10.1126/science.2113314 · Cited by 1,857 · see citing works

Stimulation of CD25(+)CD4(+) regulatory T cells through GITR breaks immunological self-tolerance

Shimizu, J., Yamazaki, S., Takahashi, T., Ishida, Y., & Sakaguchi, S. (2002) · Nature Immunology · doi:10.1038/ni759 · Cited by 1,729 · see citing works

Immunologic tolerance maintained by CD25+ CD4+ regulatory T cells: their common role in controlling autoimmunity, tumor immunity, and transplantation tolerance

Sakaguchi, S., Sakaguchi, N., Shimizu, J., Yamazaki, S., Sakihama, T., Itoh, M., Kuniyasu, Y., Nomura, T., Toda, M., & Takahashi, T. (2001) · Immunological Reviews · doi:10.1034/j.1600-065x.2001.1820102.x · Cited by 1,505 · see citing works

Demonstration of an interferon γ-dependent tumor surveillance system in immunocompetent mice

Kaplan, D. H., Shankaran, V., Dighe, A. S., Stockert, E., Aguet, M., Old, L. J., & Schreiber, R. D. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.13.7556 · Cited by 1,465 · see citing works

CD4+CD25+ Immunoregulatory T Cells

McHugh, R. S., Whitters, M. J., Piccirillo, C. A., Young, D. A., Shevach, E. M., Collins, M., & Byrne, M. C. (2002) · Immunity · doi:10.1016/s1074-7613(02)00280-7 · Cited by 1,395 · see citing works

Melanoma Cell Expression of Fas(Apo-1/CD95) Ligand: Implications for Tumor Immune Escape

Hahne, M., Rimoldi, D., Schröter, M., Romero, P. J., Schreier, M. H., French, L. E., Schneider, P., Bornand, T., Fontana, A., Liénard, D., et al. (1996) · Science · doi:10.1126/science.274.5291.1363 · Cited by 1,236 · see citing works

Expression of cyclooxygenase-1 and -2 in human colorectal cancer.

Sano, H., Kawahito, Y., Wilder, R. L., Hashiramoto, A., Mukai, S., Asai, K., Kimura, S., Kato, H., Kondo, M., & Hla, T. (1995) · PubMed · Cited by 1,126 · see citing works

Rae1 and H60 ligands of the NKG2D receptor stimulate tumour immunity

Diefenbach, A., Jensen, E. R., Jamieson, A. M., & Raulet, D. H. (2001) · Nature · doi:10.1038/35093109 · Cited by 1,083 · see citing works

Broad tumor-associated expression and recognition by tumor-derived γδ T cells of MICA and MICB

Groh, V., Rhinehart, R. L., Secrist, H., Bauer, S., Grabstein, K. H., & Spies, T. A. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.12.6879 · Cited by 1,026 · see citing works

Reciprocal Activating Interaction between Natural Killer Cells and Dendritic Cells

Gerosa, F., Baldani‐Guerra, B., Nisii, C., Marchesini, V., Carra, G., & Trinchieri, G. (2002) · The Journal of Experimental Medicine · doi:10.1084/jem.20010938 · Cited by 1,024 · see citing works

Synergism of cytotoxic T lymphocyte-associated antigen 4 blockade and depletion of CD25+ regulatory T cells in antitumor therapy reveals alternative pathways for suppression of autoreactive cytotoxic T lymphocyte responses

Sutmuller, R. P. M., van Duivenvoorde, L. M., van Elsas, A., Schumacher, T. N. M., Wildenberg, M. E., Allison, J. P., Toes, R. E. M., Offringa, R., & Melief, C. J. M. (2001) · The Journal of Experimental Medicine · doi:10.1084/jem.194.6.823 · Cited by 1,008 · see citing works

Regulation of Cutaneous Malignancy by γδ T Cells

Girardi, M., Oppenheim, D. E., Steele, C. R., Lewis, J. M., Glusac, E. J., Filler, R. B., Hobby, P., Sutton, B. J., Tigelaar, R. E., & Hayday, A. (2001) · Science · doi:10.1126/science.1063916 · Cited by 1,002 · see citing works

Caspase activation: The induced-proximity model

Salvesen, G. S., & Dixit, V. M. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.20.10964 · Cited by 932 · see citing works

Lymphocyte apoptosis induced by CD95 (APO–1/Fas) ligand–expressing tumor cells — A mechanism of immune evasion?

Strand, S., Hofmann, W. J., Hug, H., Müller, M., Otto, G., Strand, D. J., Mariani, S. M., Stremmel, W., Krammer, P. H., & Galle, P. R. (1996) · Nature Medicine · doi:10.1038/nm1296-1361 · Cited by 897 · see citing works

The Fas counterattack: Fas-mediated T cell killing by colon cancer cells expressing Fas ligand.

O’Connell, J., O’Sullivan, G. C., Collins, J. K., & Shanahan, F. (1996) · The Journal of Experimental Medicine · doi:10.1084/jem.184.3.1075 · Cited by 873 · see citing works

Expression of cyclooxygenase-2 in human gastric carcinoma.

Ristimäki, A., Honkanen, N., Jänkälä, H., Sipponen, P., & Härkönen, M. (1997) · PubMed · Cited by 813 · see citing works

Induction of Lymphocyte Apoptosis by Tumor Cell Secretion of FasL-bearing Microvesicles

Andreola, G., Rivoltini, L., Castelli, C., Huber, V., Perego, P., Deho, P., Squarcina, P., Accornero, P., Lozupone, F., Lugini, L., et al. (2002) · The Journal of Experimental Medicine · doi:10.1084/jem.20011624 · Cited by 773 · see citing works

Overweight as an avoidable cause of cancer in Europe

Bergström, A., Pisani, P., Tenet, V., Wolk, A., & Adami, H. (2001) · International Journal of Cancer · doi:10.1002/1097-0215(200002)9999:9999 · Cited by 772 · see citing works

Involvement of tumor necrosis factor-related apoptosis-inducing ligand in surveillance of tumor metastasis by liver natural killer cells

Takeda, K., Hayakawa, Y., Smyth, M. J., Kayagaki, N., Yamaguchi, N., Kakuta, S., Iwakura, Y., Yagita∥, H., & Okumura, K. (2001) · Nature Medicine · doi:10.1038/83416 · Cited by 771 · see citing works

Implications for immunosurveillance of altered HLA class I phenotypes in human tumours

Garrido, F., Ruiz‐Cabello, F., Cabrera, T., Pérez‐Villar, J. J., López‐Botet, M., Duggan-Keen, M. F., & Stern, P. L. (1997) · Immunology Today · doi:10.1016/s0167-5699(96)10075-x · Cited by 768 · see citing works

Expression of cyclooxygenase-2 in human lung carcinoma.

Wolff, H. J., Saukkonen, K., Anttila, S. L., Karjalainen, A., Vainio, H., & Ristimaki, A. P. (1998) · PubMed · Cited by 722 · see citing works

Clinical significance of defective dendritic cell differentiation in cancer.

Almand, B., Resser, J. R., Lindman, B. R., Nadaf, S., Clark, J. I., Kwon, E. D., Carbone, D. P., & Gabrilovich, D. I. (2000) · PubMed · Cited by 699 · see citing works

NKT cell–mediated repression of tumor immunosurveillance by IL-13 and the IL-4R–STAT6 pathway

Terabe, M., Matsui, S., Noben-Trauth, N., Chen, H., Watson, L. C., Donaldson, D. D., Carbone, D. P., Paul, W. E., & Berzofsky, J. A. (2000) · Nature Immunology · doi:10.1038/82771 · Cited by 698 · see citing works

Identification of human cancers deficient in antigen processing.

Restifo, N. P., Esquivel-Guadarrama, F. R., Kawakami, Y., Yewdell, J. W., Mulé, J. J., Rosenberg, S. A., & Bennink, J. R. (1993) · The Journal of Experimental Medicine · doi:10.1084/jem.177.2.265 · Cited by 624 · see citing works

Perforin-Mediated Cytotoxicity Is Critical for Surveillance of Spontaneous Lymphoma

Smyth, M. J., Thia, K. Y. T., Street, S. E. A., MacGregor, D. P., Godfrey, D. I., & Trapani, J. A. (2000) · The Journal of Experimental Medicine · doi:10.1084/jem.192.5.755 · Cited by 577 · see citing works

Effect of interleukin‐10 on dendritic cell maturation and function

Smedt, T. D., van Mechelen, M., Becker, G. D., Urbain, J., Léo, O., & Moser, M. (1997) · European Journal of Immunology · doi:10.1002/eji.1830270526 · Cited by 564 · see citing works

Loss of Functional Beta2-Microglobulin in Metastatic Melanomas From Five Patients Receiving Immunotherapy

Restifo, N. P., Marincola, F. M., Kawakami, Y., Taubenberger, J. K., Yannelli, J. R., & Rosenberg, S. A. (1996) · JNCI Journal of the National Cancer Institute · doi:10.1093/jnci/88.2.100 · Cited by 533 · see citing works

Vascular endothelial growth factor affects dendritic cell maturation through the inhibition of nuclear factor-kappa B activation in hemopoietic progenitor cells.

Oyama, T., Ran, S., Ishida, T., Nadaf, S., Kerr, L. D., Carbone, D. P., & Gabrilovich, D. I. (1998) · PubMed · Cited by 530 · see citing works

Non-small cell lung cancer cyclooxygenase-2-dependent regulation of cytokine balance in lymphocytes and macrophages: up-regulation of interleukin 10 and down-regulation of interleukin 12 production.

Huang, M., Stolina, M., Sharma, S. P., Mao, J. T., Zhu, L. X., Miller, P. W., Wollman, J. S., Herschman, H. R., & Dubinett, S. M. (1998) · PubMed · Cited by 492 · see citing works

Vascular Endothelial Growth Factor Affects Dendritic Cell Maturation Through the Inhibition of Nuclear Factor-κB Activation in Hemopoietic Progenitor Cells

Oyama, T., Ran, S., Ishida, T., Nadaf, S., Kerr, L. D., Carbone, D. P., & Gabrilovich, D. I. (1998) · The Journal of Immunology · doi:10.4049/jimmunol.160.3.1224 · Cited by 483 · see citing works

The development of lymphomas in families with autoimmune lymphoproliferative syndrome with germline Fas mutations and defective lymphocyte apoptosis

Straus, S. E. (2001) · Blood · doi:10.1182/blood.v98.1.194 · Cited by 464 · see citing works

Critical Role for Tumor Necrosis Factor–related Apoptosis-inducing Ligand in Immune Surveillance Against Tumor Development

Takeda, K., Smyth, M. J., Cretney, E., Hayakawa, Y., Kayagaki, N., Yagita∥, H., & Okumura, K. (2002) · The Journal of Experimental Medicine · doi:10.1084/jem.20011171 · Cited by 462 · see citing works

Tumor immunogenicity determines the effect of B7 costimulation on T cell-mediated tumor immunity.

Chen, L., McGowan, P., Ashe, S. A., Johnston, J. A., Li, Y., Hellström, I., & Hellström, K. E. (1994) · The Journal of Experimental Medicine · doi:10.1084/jem.179.2.523 · Cited by 462 · see citing works

TGF-β Released by Apoptotic T Cells Contributes to an Immunosuppressive Milieu

Chen, W., Frank, M., Jin, W., & Wahl, S. M. (2001) · Immunity · doi:10.1016/s1074-7613(01)00147-9 · Cited by 417 · see citing works

Human lung carcinomas express Fas ligand.

Niehans, G. A., Brunner, T., Frizelle, S. P., Liston, J. C., Salerno, C. T., Knapp, D., Green, D. R., & Kratzke, R. A. (1997) · PubMed · Cited by 395 · see citing works

Regulation of the Proinflammatory Effects of Fas Ligand (CD95L)

Chen, J., Sun, Y., & Nabel, G. J. (1998) · Science · doi:10.1126/science.282.5394.1714 · Cited by 379 · see citing works

The onset and extent of genomic instability in sporadic colorectal tumor progression

Stoler, D. L., Chen, N., Basik, M., Kahlenberg, M. S., Rodrı́guez-Bigas, M. A., Petrelli, N. J., & Anderson, G. R. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.26.15121 · Cited by 378 · see citing works

Suppression of Lymphoma and Epithelial Malignancies Effected by Interferon γ

Street, S. E. A., Trapani, J. A., MacGregor, D. P., & Smyth, M. J. (2002) · The Journal of Experimental Medicine · doi:10.1084/jem.20020063 · Cited by 375 · see citing works

Blockade of the granzyme B/perforin pathway through overexpression of the serine protease inhibitor PI-9/SPI-6 constitutes a mechanism for immune escape by tumors

Medema, J. P., de Jong, J., Peltenburg, L. T. C., Verdegaal, E. M. E., Gorter, A., Bres-Vloemans, S. A., Franken, K. L. M. C., Hahne, M., Albar, J. P., Melief, C. J. M., et al. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.201398198 · Cited by 357 · see citing works

Immunohistochemical staining for transforming growth factor beta 1 associates with disease progression in human breast cancer.

Gorsch, S. M., Memoli, V. A., Stukel, T. A., Gold, L. I., & Arrick, B. A. (1992) · PubMed · Cited by 343 · see citing works

Somatic Fas Mutations in Non-Hodgkin’s Lymphoma: Association With Extranodal Disease and Autoimmunity

Grønbæk, K., Straten, P. T., Ralfkiaer, E. M., Ahrenkiel, V., Andersen, M. K., Hansen, N. E., Zeuthen, J., HOU-JENSEN, K., & Guldberg, P. (1998) · Blood · doi:10.1182/blood.v92.9.3018 · Cited by 336 · see citing works

Immune Escape of Tumors in Vivo by Expression of Cellular Flice-Inhibitory Protein

Medema, J. P., de Jong, J., van Hall, T., Melief, C. J. M., & Offringa, R. (1999) · The Journal of Experimental Medicine · doi:10.1084/jem.190.7.1033 · Cited by 330 · see citing works

Cutting Edge: Depletion of CD4+CD25+ Regulatory T Cells Is Necessary, But Not Sufficient, for Induction of Organ-Specific Autoimmune Disease

McHugh, R. S., & Shevach, E. M. (2002) · The Journal of Immunology · doi:10.4049/jimmunol.168.12.5979 · Cited by 319 · see citing works

Immune suppression and skin cancer development: regulation by NKT cells

Moodycliffe, A. M., Nghiem, D. X., Clydesdale, G. J., & Ullrich, S. E. (2000) · Nature Immunology · doi:10.1038/82782 · Cited by 318 · see citing works

Pancreatic Lymph Node-Derived CD4+CD25+ Treg Cells

Green, E. A., Choi, Y., & Flavell, R. A. (2002) · Immunity · doi:10.1016/s1074-7613(02)00279-0 · Cited by 310 · see citing works

MHC antigens and tumor escape from immune surveillance

Garrido, F., & Algarra, I. (2001) · Advances in cancer research · doi:10.1016/s0065-230x(01)83005-0 · Cited by 305 · see citing works

Spontaneous apoptosis of dendritic cells is efficiently inhibited by TRAP (CD40‐ligand) and TNF‐α, but strongly enhanced by interleukin‐10

Ludewig, B., Graf, D., Gelderblom, H., Becker, Y., Kroczek, R., & Pauli, G. (1995) · European Journal of Immunology · doi:10.1002/eji.1830250722 · Cited by 267 · see citing works

Not so Fas: Re-evaluating the mechanisms of immune privilege and tumor escape

Restifo, N. P. (2000) · Nature Medicine · doi:10.1038/74955 · Cited by 251 · see citing works

A New Mechanism of NK Cell Cytotoxicity Activation: The CD40–CD40 Ligand Interaction

Carbone, E., Ruggiero, G., Terrazzano, G., Palomba, C., Manzo, C., Fontana, S., Spits, H., Kärre, K., & Zappacosta, S. (1997) · The Journal of Experimental Medicine · doi:10.1084/jem.185.12.2053 · Cited by 249 · see citing works

T Cell-Derived IL-10 Promotes Lung Cancer Growth by Suppressing Both T Cell and APC Function

Sharma, S. P., Stolina, M., Lin, Y., Gardner, B. K., Miller, P. W., Kronenberg, M., & Dubinett, S. M. (1999) · The Journal of Immunology · doi:10.4049/jimmunol.163.9.5020 · Cited by 248 · see citing works

Gene transfer of Fas ligand induces tumor regression in vivo

Arai, H., Gordon, D., Nabel, E. G., & Nabel, G. J. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.25.13862 · Cited by 247 · see citing works

Mutations in the Fas Antigen in Patients With Multiple Myeloma

Landowski, T. H., Qu, N., Buyuksal, I., Painter, J. S., & Dalton, W. S. (1997) · Blood · doi:10.1182/blood.v90.11.4266.4266_4266_4270 · Cited by 243 · see citing works

Molecular Characterization of Defective Antigen Processing in Human Prostate Cancer

Sanda, M. G., Restifo, N. P., Walsh, J. C., Kawakami, Y., Nelson, W. G., Pardoll, D. M., & Simons, J. W. (1995) · JNCI Journal of the National Cancer Institute · doi:10.1093/jnci/87.4.280 · Cited by 236 · see citing works

How melanoma cells evade trail-induced apoptosis

Hersey, P., & Zhang, X. D. (2001) · Nature reviews. Cancer · doi:10.1038/35101078 · Cited by 211 · see citing works

Downregulation of TAP1 in B Lymphocytes by Cellular and Epstein-Barr Virus–Encoded Interleukin-10

Zeidler, R., Eißner, G., Meissner, P., Uebel, S. F. W., Tampé, R., Lazis, S., & Hammerschmidt, W. (1997) · Blood · doi:10.1182/blood.v90.6.2390 · Cited by 204 · see citing works

beta2-Microglobulin mutations, HLA class I antigen loss, and tumor progression in melanoma.

Hicklin, D. J., Wang, Z., Arienti, F., Rivoltini, L., Parmiani, G., & Ferrone, S. (1998) · Journal of Clinical Investigation · doi:10.1172/jci498 · Cited by 198 · see citing works

Loss of antigen-presenting molecules (MHC class I and TAP-1) in lung cancer

Korkolopoulou, P., Kaklamanis, L., Pezzella, F., Harris, A. L., & Gatter, K. (1996) · British Journal of Cancer · doi:10.1038/bjc.1996.28 · Cited by 192 · see citing works

Spontaneous Development of Plasmacytoid Tumors in Mice with Defective Fas–Fas Ligand Interactions

Davidson, W. F., Giese, T., & Fredrickson, T. N. (1998) · The Journal of Experimental Medicine · doi:10.1084/jem.187.11.1825 · Cited by 190 · see citing works

Heterogeneous expression of immunotherapy candidate proteins gp100, MART-1, and tyrosinase in human melanoma cell lines and in human melanocytic lesions.

de Vries, T. J., Fourkour, A., Wobbes, T., Verkroost, G., Ruiter, D. J., & van Muijen, G. N. P. (1997) · PubMed · Cited by 187 · see citing works

High frequency of altered HLA class I phenotypes in invasive colorectal carcinomas

Cabrera, T., Collado, A., Fernandez, M. A., Ferron, A., Sancho, J., Ruiz‐Cabello, F., & Garrido, F. (1998) · Tissue Antigens · doi:10.1111/j.1399-0039.1998.tb02274.x · Cited by 175 · see citing works

Diet and risk of cutaneous malignant melanoma: A prospective study of 50,757 Norwegian men and women

Veierød, M. B., Thelle, D. S., & Laake, P. (1997) · International Journal of Cancer · doi:10.1002/(sici)1097-0215(19970516)71:4 · Cited by 169 · see citing works

Immune selection after antigen-specific immunotherapy of melanoma

Riker, A. I., Cormier, J. N., Panelli, M. C., Kammula, U. S., Wang, E., Abati, A. D., Fetsch, P. A., Lee, K.-H., Steinberg, S. M., Rosenberg, S. A., et al. (1999) · Surgery · doi:10.1016/s0039-6060(99)70143-1 · Cited by 164 · see citing works

Transforming growth factor-beta inhibits the generation of cytotoxic T cells in virus-infected mice.

Fontana, A., Frei, K., Bodmer, S., Hofer, E., Schreier, M. H., Palladino, M. A., & Zinkernagel, R. M. (1989) · The Journal of Immunology · doi:10.4049/jimmunol.143.10.3230 · Cited by 160 · see citing works

Inactivating mutations of CASP10 gene in non-Hodgkin lymphomas

Shin, M. S., Kim, H. S., Kang, C. S., Park, W. S., Kim, S. Y., Lee, S. N., Lee, J., Park, J. Y., Jang, J. J., Kim, C. W., et al. (2002) · Blood · doi:10.1182/blood.v99.11.4094 · Cited by 147 · see citing works

Relationship between the expression of vascular endothelial growth factor and the density of dendritic cells in gastric adenocarcinoma tissue

Saito, H., Tsujitani, S., Ikeguchi, M., Maeta, M., & Kaibara, N. (1998) · British Journal of Cancer · doi:10.1038/bjc.1998.725 · Cited by 142 · see citing works

Alterations of Fas (Apo-1/CD95) Gene in Cutaneous Malignant Melanoma

Shin, M. S., Park, W. S., Kim, S., Kim, H. S., Kang, S. J., Song, K. Y., Park, J. Y., Dong, S. M., Pi, J. H., Oh, R. R., et al. (1999) · American Journal Of Pathology · doi:10.1016/s0002-9440(10)65434-x · Cited by 137 · see citing works

Dendritic cells hold promise for immunotherapy

Girolomoni, G., & Ricciardi‐Castagnoli, P. (1997) · Immunology Today · doi:10.1016/s0167-5699(97)01030-x · Cited by 133 · see citing works

Human melanoma cells do not express Fas (Apo-1/CD95) ligand.

Chappell, D. B., Zaks, T. Z., Rosenberg, S. A., & Restifo, N. P. (1999) · PubMed · Cited by 133 · see citing works

CD27-Mediated Activation of Murine NK Cells

Takeda, K., Oshima, H., Hayakawa, Y., Akiba, H., Atsuta, M., Kobata, T., Kobayashi, K., Ito, M., Yagita∥, H., & Okumura, K. (2000) · The Journal of Immunology · doi:10.4049/jimmunol.164.4.1741 · Cited by 132 · see citing works

High frequency of altered HLA class I phenotypes in invasive breast carcinomas

Cabrera, T., Fernandez, M. A., Sierra, À., Garrido, A., Herruzo, A., Escobedo, A., Fabra, À., & Garrido, F. (1996) · Human Immunology · doi:10.1016/0198-8859(96)00145-0 · Cited by 126 · see citing works

Functional Dissociation Between Local and Systemic Immune Response During Anti-Melanoma Peptide Vaccination

Lee, K.-H., Panelli, M. C., Kim, C. J., Riker, A. I., Bettinotti, M. P., Roden, M. M., Fetsch, P. A., Abati, A. D., Rosenberg, S. A., & Marincola, F. M. (1998) · The Journal of Immunology · doi:10.4049/jimmunol.161.8.4183 · Cited by 124 · see citing works

Fas-Mediated Suicide of Tumor-Reactive T Cells Following Activation by Specific Tumor: Selective Rescue by Caspase Inhibition

Zaks, T. Z., Chappell, D. B., Rosenberg, S. A., & Restifo, N. P. (1999) · The Journal of Immunology · doi:10.4049/jimmunol.162.6.3273 · Cited by 123 · see citing works

Immunodominance and tumor escape

Schreiber, H. W., Wu, T. H., Nachman, J. B., & Kast, W. M. (2002) · Seminars in Cancer Biology · doi:10.1006/scbi.2001.0401 · Cited by 117 · see citing works

Suppression of class I human histocompatibility leukocyte antigen by c-myc is locus specific.

Versteeg, R., Krüse, K. M., Plomp, A. C., LEEUWEN, A. V., Stam, N. J., Ploegh, H. L., Ruiter, D. J., & Schrier, P. I. (1989) · The Journal of Experimental Medicine · doi:10.1084/jem.170.3.621 · Cited by 112 · see citing works

Natural killer cell lines kill autologous β 2 -microglobulin-deficient melanoma cells: Implications for cancer immunotherapy

Porgador, A., Mandelboim, O., Restifo, N. P., & Strominger, J. L. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.24.13140 · Cited by 109 · see citing works

Clinical significance of the determination of angiogenic factors

Toi, M., Taniguchi, T., Yamamoto, Y., Kurisaki, T., Suzuki, H., & Tominaga, T. (1996) · European Journal of Cancer · doi:10.1016/s0959-8049(96)00397-8 · Cited by 107 · see citing works

Down-regulation of the expression and function of the transporter associated with antigen processing in murine tumor cell lines expressing IL-10

Salazar‐Onfray, F., Charo, J., Petersson, M., Freland, S., Noffz, G., Qin, Z., Blankenstein, T., Ljunggren, H., & Kiessling, R. W. (1997) · The Journal of Immunology · doi:10.4049/jimmunol.159.7.3195 · Cited by 89 · see citing works

Expression of a Variant of CD28 on a Subpopulation of Human NK Cells: Implications for B7-Mediated Stimulation of NK Cells

Galea‐Lauri, J., Darling, D. C., Gan, S. U., Krivochtchapov, L., Kuiper, M., Gäken, J. A., Souberbielle, B. E., & Farzaneh, F. (1999) · The Journal of Immunology · doi:10.4049/jimmunol.163.1.62 · Cited by 85 · see citing works

Melan A/MART-1 immunoreactivity in formalin-fixed paraffin-embedded primary and metastatic melanoma: frequency and distribution

Hofbauer, G. F. L., Kamarashev, J. A., Geertsen, R., B�ni, R., & Dummer, R. (1998) · Melanoma Research · doi:10.1097/00008390-199808000-00007 · Cited by 81 · see citing works

Alterations of Fas-pathway genes associated with nodal metastasis innon-small cell lung cancer

Shin, M. S., Kim, H. S., Lee, S. H., Lee, J. W., Song, Y. H., Kim, Y. S., Park, W. S., Kim, S. Y., Lee, S. N., Park, J. Y., et al. (2002) · Oncogene · doi:10.1038/sj.onc.1205527 · Cited by 76 · see citing works

Two mechanisms for tumor evasion of preexisting cytotoxic T-cell responses: lessons from recurrent tumors.

Zheng, P., Sarma, S., Guo, Y., & Liu, Y. (1999) · PubMed · Cited by 75 · see citing works

Countering the 'counterattack' hypothesis

Restifo, N. P. (2001) · Nature Medicine · doi:10.1038/85357 · Cited by 74 · see citing works

Do CD4+CD25+ Immunoregulatory T Cells Hinder Tumor Immunotherapy?

Antony, P. A., & Restifo, N. P. (2002) · Journal of Immunotherapy · doi:10.1097/00002371-200205000-00002 · Cited by 68 · see citing works

Altered MHC class I antigens in tumors

Algarra, I., Collado, A., & Garrido, F. (1997) · International Journal of Clinical & Laboratory Research · doi:10.1007/bf02912442 · Cited by 64 · see citing works

Pillars Article: Regulation of Cutaneous Malignancy by γδ T Cells. Science. 2001. 294: 605–609

Girardi, M., Oppenheim, D. E., Steele, C. R., Lewis, J. M., Glusac, E. J., Filler, R. B., Hobby, P., Sutton, B. J., Tigelaar, R. E., & Hayday, A. (2018) · The Journal of Immunology · doi:10.1093/jimmunol/200.9.3031 · Cited by 64 · see citing works

Local inhibition of natural killer cell activity promotes the progressive growth of intraocular tumors.

Apte, R. S., Mayhew, E. S., & Niederkorn, J. Y. (1997) · PubMed · Cited by 60 · see citing works

Pharmacokinetics, biodistribution and biological effects of intravenously administered bispecific monoclonal antibody OC/TR F(ab′)2 in ovarian carcinoma patients

Tibben, J. G., Boerman, O. C., Massuger, L. F. A. G., Schijf, C. P. T., Claessens, R. A. M. J., & Corstens, F. H. M. (1996) · International Journal of Cancer · doi:10.1002/(sici)1097-0215(19960516)66:4 · Cited by 60 · see citing works

Molecular strategies to define HLA haplotype loss in microdissected tumor cells

Ramal, L. M., Maleno, I., Cabrera, T., Collado, A., Ferrón, A., López‐Nevot, M. Á., & Garrido, F. (2000) · Human Immunology · doi:10.1016/s0198-8859(00)00171-3 · Cited by 60 · see citing works

v-src induces cisplatin resistance by increasing the repair of cisplatin-DNA interstrand cross-links in human gallbladder adenocarcinoma cells

Masumoto, N., Nakano, S., Fujishima, H., Kohno, K., & Niho, Y. (1999) · International Journal of Cancer · doi:10.1002/(sici)1097-0215(19990301)80:5 · Cited by 57 · see citing works

Locus-specific transcriptional control of HLA genes

Soong, T. W., & Hui, K. M. (1992) · The Journal of Immunology · doi:10.4049/jimmunol.149.6.2008 · Cited by 56 · see citing works

Human Leukocyte Antigen Class I Gene Mutations in Cervical Cancer

Koopman, L. A., van der Slik, A. R., Giphart, M. J., & Fleuren, G. J. (1999) · JNCI Journal of the National Cancer Institute · doi:10.1093/jnci/91.19.1669 · Cited by 55 · see citing works

Locus-Specific Analysis of Human Leukocyte Antigen Class I Expression in Melanoma Cell Lines

Marincola, F. M., Shamamian, P. E., Simonis, T. B., Abati, A. D., Hackett, J., Dea, T. O., Fetsch, P. A., Yannelli, J. R., Restifo, N. P., Mulé, J. J., et al. (1994) · Journal of Immunotherapy · doi:10.1097/00002371-199407000-00002 · Cited by 51 · see citing works

Expression and function of the peptide transporters in escape variants of human renal cell carcinomas.

Seliger, B., Höhne, A., Jung, D., Kallfelz, M., Knuth, A., Jaeger, E., Bernhard, H., Momburg, F., Tampé, R., & Huber, C. G. (1997) · PubMed · Cited by 40 · see citing works

Assumptions of the tumor ‘escape’ hypothesis

Restifo, N. P., Antony, P. A., Finkelstein, S. E., Leitner, W. W., Surman, D. R., Theoret, M. R., & Touloukian, C. E. (2002) · Seminars in Cancer Biology · doi:10.1006/scbi.2001.0399 · Cited by 34 · see citing works

Fas Ligand Expression on Islets as Well as Multiple Cell Lines Results in Accelerated Neutrophilic Rejection

Kang, S., Lin, Z., Ascher, N. L., & Stock, P. G. (1998) · Transplantation Proceedings · doi:10.1016/s0041-1345(97)01396-1 · Cited by 26 · see citing works

Death Receptor Ligands in Tumors

Cappello, P., Novelli, F., Forni, G., & Giovarelli, M. (2002) · Journal of Immunotherapy · doi:10.1097/00002371-200201000-00001 · Cited by 26 · see citing works

Antitumor effect of allogenic fibroblasts engineered to express Fas ligand (FasL)

Droździk, M., Qian, C., Lasarte, J. J., Bilbao, R., & Prìeto, J. (1998) · Gene Therapy · doi:10.1038/sj.gt.3300763 · Cited by 23 · see citing works

Oncogene and Cytokine Expression of Human Colorectal Tumors Responding to Immunotherapy

Doran, T., Stuhlmiller, H., Kim, J. A., Martin, E. W., & Triozzi, P. L. (1997) · Journal of Immunotherapy · doi:10.1097/00002371-199709000-00006 · Cited by 15 · see citing works

Untitled work

Rodriguez-Palmero, M. (1999) · doi:10.1002/(sici)1521-4141(199912)29:12

Microenvironmental regulation of tumor progression and metastasis

Quail, D. F., & Joyce, J. A. (2013) · Nature Medicine · doi:10.1038/nm.3394 · Cited by 7,994 · see citing works

Cancer Immunoediting: Integrating Immunity’s Roles in Cancer Suppression and Promotion

Schreiber, R. D., Old, L. J., & Smyth, M. J. (2011) · Science · doi:10.1126/science.1203486 · Cited by 6,474 · see citing works

Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival

Curiel, T. J., Coukos, G., Zou, L., Alvarez, X., Cheng, P., Mottram, P., Evdemon-Hogan, M., Conejo-Garcia, J. R., Zhang, L., Burow, M., et al. (2004) · Nature Medicine · doi:10.1038/nm1093 · Cited by 5,151 · see citing works

Molecular and genetic properties of tumors associated with local immune cytolytic activity

Rooney, M. S., Shukla, S. A., Wu, C. J., Getz, G., & Hacohen, N. (2015) · Cell · doi:10.1016/j.cell.2014.12.033 · Cited by 3,825 · see citing works

The Three Es of Cancer Immunoediting

Dunn, G. P., Old, L. J., & Schreiber, R. D. (2004) · Annual Review of Immunology · doi:10.1146/annurev.immunol.22.012703.104803 · Cited by 3,087 · see citing works

The Immunobiology of Cancer Immunosurveillance and Immunoediting

Dunn, G. P., Old, L. J., & Schreiber, R. D. (2004) · Immunity · doi:10.1016/j.immuni.2004.07.017 · Cited by 3,036 · see citing works

The history and advances in cancer immunotherapy: understanding the characteristics of tumor-infiltrating immune cells and their therapeutic implications

Zhang, Y., & Zhang, Z. (2020) · Cellular and Molecular Immunology · doi:10.1038/s41423-020-0488-6 · Cited by 2,815 · see citing works

Natural Innate and Adaptive Immunity to Cancer

Vesely, M. D., Kershaw, M. H., Schreiber, R. D., & Smyth, M. J. (2011) · Annual Review of Immunology · doi:10.1146/annurev-immunol-031210-101324 · Cited by 2,095 · see citing works

Regulatory T cells, tumour immunity and immunotherapy

Zou, W. (2006) · Nature reviews. Immunology · doi:10.1038/nri1806 · Cited by 2,075 · see citing works

Immunosuppressive networks in the tumour environment and their therapeutic relevance

Zou, W. (2005) · Nature Reviews Cancer · doi:10.1038/nrc1586 · Cited by 2,057 · see citing works

Immunosuppressive Strategies that are Mediated by Tumor Cells

Rabinovich, G. A., Gabrilovich, D. I., & Sotomayor, E. M. (2006) · Annual Review of Immunology · doi:10.1146/annurev.immunol.25.022106.141609 · Cited by 1,699 · see citing works

Adoptive immunotherapy for cancer: harnessing the T cell response

Restifo, N. P., Dudley, M. E., & Rosenberg, S. A. (2012) · Nature Reviews Immunology · doi:10.1038/nri3191 · Cited by 1,688 · see citing works

Inhibitory B7-family molecules in the tumour microenvironment

Zou, W., & Chen, L. (2008) · Nature Reviews Immunology · doi:10.1038/nri2326 · Cited by 1,608 · see citing works

Tumor aneuploidy correlates with markers of immune evasion and with reduced response to immunotherapy

Davoli, T., Uno, H., Wooten, E. C., & Elledge, S. J. (2017) · Science · doi:10.1126/science.aaf8399 · Cited by 1,365 · see citing works

From chemotherapy to biological therapy: A review of novel concepts to reduce the side effects of systemic cancer treatment (Review)

Schirrmacher, V. (2018) · International Journal of Oncology · doi:10.3892/ijo.2018.4661 · Cited by 1,303 · see citing works

Cancer exome analysis reveals a T-cell-dependent mechanism of cancer immunoediting

Matsushita, H., Vesely, M. D., Koboldt, D. C., Rickert, C. G., Uppaluri, R., Magrini, V. J., Arthur, C. D., White, J. M., Chen, Y.-S., Shea, L. K., et al. (2012) · Nature · doi:10.1038/nature10755 · Cited by 1,285 · see citing works

Microenvironment-induced PTEN loss by exosomal microRNA primes brain metastasis outgrowth

Zhang, L., Zhang, S., Yao, J., Lowery, F. J., Zhang, Q., Huang, W.-C., Li, P., Li, M., Wang, X., Zhang, C., et al. (2015) · Nature · doi:10.1038/nature15376 · Cited by 1,154 · see citing works

Inflammation, a Key Event in Cancer Development

Lu, H., Ouyang, W., & Huang, C. (2006) · Molecular Cancer Research · doi:10.1158/1541-7786.mcr-05-0261 · Cited by 1,031 · see citing works

Targeting neoantigens to augment antitumour immunity

Yarchoan, M., Johnson, B. A., Lutz, E. R., Laheru, D. A., & Jaffee, E. M. (2017) · Nature Reviews Cancer · doi:10.1038/nrc.2016.154 · Cited by 997 · see citing works

Cancer Immunosurveillance and Immunoediting: The Roles of Immunity in Suppressing Tumor Development and Shaping Tumor Immunogenicity

Smyth, M. J., Dunn, G. P., & Schreiber, R. D. (2006) · Advances in immunology · doi:10.1016/s0065-2776(06)90001-7 · Cited by 872 · see citing works

Expression of indoleamine 2,3-dioxygenase by plasmacytoid dendritic cells in tumor-draining lymph nodes

Munn, D. H., Sharma, M. D., Hou, D., Baban, B., Lee, J. R., Antonia, S. J., Messina, J. L., Chandler, P., Koni, P. A., & Mellor, A. L. (2004) · Journal of Clinical Investigation · doi:10.1172/jci21583 · Cited by 852 · see citing works

Adoptive immunotherapy for cancer: building on success

Gattinoni, L., Powell, D. J., Rosenberg, S. A., & Restifo, N. P. (2006) · Nature reviews. Immunology · doi:10.1038/nri1842 · Cited by 841 · see citing works

Myeloid suppressor cells in cancer: Recruitment, phenotype, properties, and mechanisms of immune suppression

Serafini, P., Borrello, I., & Bronte, V. (2005) · Seminars in Cancer Biology · doi:10.1016/j.semcancer.2005.07.005 · Cited by 758 · see citing works

B7-H4 expression identifies a novel suppressive macrophage population in human ovarian carcinoma

Kryczek, I., Zou, L., Rodriguez, P., Zhu, G., Wei, S., Mottram, P., Brumlik, M., Cheng, P., Curiel, T., Myers, L., et al. (2006) · The Journal of Experimental Medicine · doi:10.1084/jem.20050930 · Cited by 748 · see citing works

Adoptive-cell-transfer therapy for the treatment of patients with cancer

Dudley, M. E., & Rosenberg, S. A. (2003) · Nature reviews. Cancer · doi:10.1038/nrc1167 · Cited by 653 · see citing works

Melanomas resist T-cell therapy through inflammation-induced reversible dedifferentiation

Landsberg, J., Sirokay, J. D., Renn, M., Bald, T., Rogava, M., Cron, M., Fatho, M., Lennerz, V., Wölfel, T., Hölzel, M., et al. (2012) · Nature · doi:10.1038/nature11538 · Cited by 635 · see citing works

Clodronate-liposome-mediated depletion of tumour-associated macrophages: a new and highly effective antiangiogenic therapy approach

Zeisberger, S. M., Odermatt, B., Marty, C., Zehnder-Fjällman, A. H. M., Ballmer‐Hofer, K., & Schwendener, R. A. (2006) · British Journal of Cancer · doi:10.1038/sj.bjc.6603240 · Cited by 622 · see citing works

Circulating and disseminated tumour cells — mechanisms of immune surveillance and escape

Mohme, M., Riethdorf, S., & Pantel, K. (2016) · Nature Reviews Clinical Oncology · doi:10.1038/nrclinonc.2016.144 · Cited by 607 · see citing works

Therapeutic Cancer Vaccines

Guo, C., Manjili, M. H., Subjeck, J. R., Sarkar, D., Fisher, P. B., & Wang, X. (2013) · Advances in cancer research · doi:10.1016/b978-0-12-407190-2.00007-1 · Cited by 598 · see citing works

Immunological landscape and immunotherapy of hepatocellular carcinoma

Prìeto, J., Melero, I., & Sangro, B. (2015) · Nature Reviews Gastroenterology & Hepatology · doi:10.1038/nrgastro.2015.173 · Cited by 564 · see citing works

CD4 and CD8 T lymphocyte interplay in controlling tumor growth

Ostroumov, D., Fekete-Drimusz, N., Saborowski, M., Kühnel, F., & Woller, N. (2017) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-017-2686-7 · Cited by 550 · see citing works

Transforming Growth Factor-β Production and Myeloid Cells Are an Effector Mechanism through Which CD1d-restricted T Cells Block Cytotoxic T Lymphocyte–mediated Tumor Immunosurveillance

Terabe, M., Matsui, S., Park, J.-M., Mamura, M., Noben-Trauth, N., Donaldson, D. D., Chen, W., Wahl, S. M., Ledbetter, S. R., Pratt, B. M., et al. (2003) · The Journal of Experimental Medicine · doi:10.1084/jem.20022227 · Cited by 539 · see citing works

Loss of Mismatched HLA in Leukemia after Stem-Cell Transplantation

Vago, L., Perna, S. K., Zanussi, M., Mazzi, B. A., Barlassina, C., Stanghellini, M. T. L., Perrelli, N. F., Cosentino, C., Torri, F., Angius, A., et al. (2009) · New England Journal of Medicine · doi:10.1056/nejmoa0811036 · Cited by 532 · see citing works

Expression of tumour-specific antigens underlies cancer immunoediting

DuPage, M. J. P., Mazumdar, C., Schmidt, L., Cheung, A. F., & Jacks, T. (2012) · Nature · doi:10.1038/nature10803 · Cited by 529 · see citing works

CD8 ⁺ T‐cell memory in tumor immunology and immunotherapy

Klebanoff, C. A., Gattinoni, L., & Restifo, N. P. (2006) · Immunological Reviews · doi:10.1111/j.0105-2896.2006.00391.x · Cited by 511 · see citing works

Impact of Stress on Cancer Metastasis

Moreno‐Smith, M., Lutgendorf, S. K., & Sood, A. K. (2010) · Future Oncology · doi:10.2217/fon.10.142 · Cited by 505 · see citing works

Clonal Origin and Evolution of a Transmissible Cancer

Murgia, C., Pritchard, J. K., Kim, S. Y., Fassati, A., & Weiss, R. A. (2006) · Cell · doi:10.1016/j.cell.2006.05.051 · Cited by 489 · see citing works

Immunotherapy: Reshape the Tumor Immune Microenvironment

Bingzhe, L. V., Wang, Y., Ma, D., Cheng, W., Liu, J., Yong, T., Chen, H., & Wang, C. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.844142 · Cited by 486 · see citing works

Acquired resistance to immunotherapy and future challenges

Restifo, N. P., Smyth, M. J., & Snyder, A. (2016) · Nature reviews. Cancer · doi:10.1038/nrc.2016.2 · Cited by 468 · see citing works

Tumor Progression Can Occur despite the Induction of Very High Levels of Self/Tumor Antigen-Specific CD8+ T Cells in Patients with Melanoma

Rosenberg, S. A., Sherry, R. M., Morton, K. E., Sharfman, W., Yang, J. C., Topalian, S. L., Royal, R. E., Kammula, U. S., Restifo, N. P., Hughes, M. S., et al. (2005) · The Journal of Immunology · doi:10.4049/jimmunol.175.9.6169 · Cited by 460 · see citing works

Recent Advances in Hyperthermia Therapy‐Based Synergistic Immunotherapy

Chang, M., Hou, Z., Wang, M., Li, C., & Lin, J. (2020) · Advanced Materials · doi:10.1002/adma.202004788 · Cited by 452 · see citing works

Sporadic immunogenic tumours avoid destruction by inducing T-cell tolerance

Willimsky, G., & Blankenstein, T. J. F. (2005) · Nature · doi:10.1038/nature03954 · Cited by 439 · see citing works

The determinants of tumour immunogenicity

Blankenstein, T. J. F., Coulie, P. G., Gilboa, E., & Jaffee, E. M. (2012) · Nature reviews. Cancer · doi:10.1038/nrc3246 · Cited by 437 · see citing works

New insights into the role of <scp>EMT</scp> in tumor immune escape

Terry, S., Savagner, P., Ortiz‐Cuaran, S., Mahjoubi, L., Saintigny, P., Thiery, J., & Chouaib, S. (2017) · Molecular Oncology · doi:10.1002/1878-0261.12093 · Cited by 414 · see citing works

Ex vivo identification, isolation and analysis of tumor-cytolytic T cells

Rubio, V., Stuge, T. B., Singh, N. S., Betts, M. R., Weber, J. S., Roederer, M., & Lee, P. P. (2003) · Nature Medicine · doi:10.1038/nm942 · Cited by 400 · see citing works

Alterations of immune response of non-small cell lung cancer with Azacytidine

Wrangle, J. M., Wang, W., Koch, A., Easwaran, H., Mohammad, H. P., Pan, X., Vendetti, F. P., Criekinge, W. V., DeMeyer, T., Du, Z., et al. (2013) · Oncotarget · doi:10.18632/oncotarget.1542 · Cited by 387 · see citing works

Plasmacytoid Dendritic Cells Induce CD8+ Regulatory T Cells In Human Ovarian Carcinoma

Wei, S., Kryczek, I., Zou, L., Daniel, B., Cheng, P. J., Mottram, P. J., Curiel, T. J., Lange, A., & Zou, W. (2005) · Cancer Research · doi:10.1158/0008-5472.can-04-4043 · Cited by 379 · see citing works

Classical and alternative activation of mononuclear phagocytes: Picking the best of both worlds for tumor promotion

Ginderachter, J. A. V., Movahedi, K., Ghassabeh, G. H., Meerschaut, S., Beschin, A., Raes, G., & BAETSELIER, P. D. (2006) · Immunobiology · doi:10.1016/j.imbio.2006.06.002 · Cited by 370 · see citing works

Cancer immunoediting: antigens, mechanisms, and implications to cancer immunotherapy

Vesely, M. D., & Schreiber, R. D. (2013) · Annals of the New York Academy of Sciences · doi:10.1111/nyas.12105 · Cited by 367 · see citing works

Prospects for gene-engineered T cell immunotherapy for solid cancers

Klebanoff, C. A., Rosenberg, S. A., & Restifo, N. P. (2016) · Nature Medicine · doi:10.1038/nm.4015 · Cited by 367 · see citing works

Increased intensity lymphodepletion and adoptive immunotherapy—how far can we go?

Muranski, P. J., Boni, A., Wrzesinski, C., Citrin, D. E., Rosenberg, S. A., Childs, R. W., & Restifo, N. P. (2006) · Nature Clinical Practice Oncology · doi:10.1038/ncponc0666 · Cited by 358 · see citing works

A Pan-cancer Landscape of Interactions between Solid Tumors and Infiltrating Immune Cell Populations

Tamborero, D., Rubio-Pérez, C., Muiños, F., Sabarinathan, R., Piulats, J. M., Muntasell, A., Dienstmann, R., López-Bigas, N., & González-Pérez, A. (2018) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-17-3509 · Cited by 358 · see citing works

Prospects of RNA interference therapy for cancer

Pai, S. I., Lin, Y.-Y., Macaes, B., Meneshian, A., Hung, C.-F., & Wu, T. ‐. (2005) · Gene Therapy · doi:10.1038/sj.gt.3302694 · Cited by 351 · see citing works

The α‐gal epitope and the anti‐Gal antibody in xenotransplantation and in cancer immunotherapy

Galili, U. (2005) · Immunology and Cell Biology · doi:10.1111/j.1440-1711.2005.01366.x · Cited by 335 · see citing works

CD4+ T cell-induced inflammatory cell death controls immune-evasive tumours

Kruse, B., Buzzai, A. C., Shridhar, N., Braun, A. D., Gellert, S., Knauth, K., Poźniak, J., Peters, J., Dittmann, P., Mengoni, M., et al. (2023) · Nature · doi:10.1038/s41586-023-06199-x · Cited by 325 · see citing works

Natural killer cells in human health and disease

Orange, J. S., & Ballas, Z. K. (2005) · Clinical Immunology · doi:10.1016/j.clim.2005.10.011 · Cited by 320 · see citing works

Dual role of macrophages in tumor growth and angiogenesis

Lamagna, C., Aurrand‐Lions, M., & Imhof, B. A. (2006) · Journal of Leukocyte Biology · doi:10.1189/jlb.1105656 · Cited by 311 · see citing works

Coordination of Intratumoral Immune Reaction and Human Colorectal Cancer Recurrence

Camus, M., Tosolini, M., Mlecnik, B., Pagès, F., Kirilovsky, A., Berger, A., Costes, A., Bindea, G., Charoentong, P., Bruneval, P., et al. (2009) · Cancer Research · doi:10.1158/0008-5472.can-08-2654 · Cited by 307 · see citing works

Adaptive Immune Resistance Emerges from Tumor-Initiating Stem Cells

Miao, Y., Yang, H., Levorse, J., Yuan, S., Polak, L., Sribour, M., Singh, B., Rosenblum, M. D., & Fuchs, E. (2019) · Cell · doi:10.1016/j.cell.2019.03.025 · Cited by 299 · see citing works

Accelerated tumor growth in mice deficient in DNAM-1 receptor

Iguchi‐Manaka, A., Kai, H., Yamashita, Y., Shibata, K., Tahara‐Hanaoka, S., Honda, S.-I., Yasui, T., Kikutani, H., Shibuya, K., & Shibuya, A. (2008) · The Journal of Experimental Medicine · doi:10.1084/jem.20081611 · Cited by 289 · see citing works

Increased Intensity Lymphodepletion Enhances Tumor Treatment Efficacy of Adoptively Transferred Tumor-specific T Cells

Wrzesinski, C., Paulos, C. M., Kaiser, A., Muranski, P. J., Palmer, D. C., Gattinoni, L., Yu, Z., Rosenberg, S. A., & Restifo, N. P. (2009) · Journal of Immunotherapy · doi:10.1097/cji.0b013e3181b88ffc · Cited by 284 · see citing works

Complete responses of relapsed lymphoma following genetic modification of tumor-antigen presenting cells and T-lymphocyte transfer

Bollard, C. M., Gottschalk, S. M., Leen, A. M., Weiss, H. L., Straathof, K. C. M., Carrum, G., Khalil, M., Wu, M., Huls, M. H., Chang, C.-C., et al. (2007) · Blood · doi:10.1182/blood-2007-05-091280 · Cited by 278 · see citing works

Role of infiltrated leucocytes in tumour growth and spread

Lin, E. Y., & Pollard, J. W. (2004) · British Journal of Cancer · doi:10.1038/sj.bjc.6601705 · Cited by 278 · see citing works

B7-H1 pathway and its role in the evasion of tumor immunity

Dong, H., & Chen, L. (2003) · Journal of Molecular Medicine · doi:10.1007/s00109-003-0430-2 · Cited by 276 · see citing works

The impact of mitotic errors on cell proliferation and tumorigenesisPreprint

Levine, M. S., & Holland, A. J. (2018) · Genes & Development · doi:10.1101/gad.314351.118 · Cited by 268 · see citing works

Plasticity of tumour and immune cells: a source of heterogeneity and a cause for therapy resistance?

Hölzel, M., Bovier, A., & Tüting, T. (2013) · Nature reviews. Cancer · doi:10.1038/nrc3498 · Cited by 267 · see citing works

HLA-E and HLA-G Expression in Classical HLA Class I-Negative Tumors Is of Prognostic Value for Clinical Outcome of Early Breast Cancer Patients

de Kruijf, E. M., Sajet, A., van Nes, J. G. H., Natanov, R., Putter, H., Smit, V. T. H. B. M., Liefers, G., van den Elsen, P. J., van de Velde, C. J. �., & Kuppen, P. J. K. (2010) · The Journal of Immunology · doi:10.4049/jimmunol.1002629 · Cited by 268 · see citing works

Human embryonic stem cells differentiate into a homogeneous population of natural killer cells with potent in vivo antitumor activity

Woll, P. S., Grzywacz, B. J., Tian, X., Marcus, R. K., Knorr, D. A., Verneris, M. R., & Kaufman, D. S. (2009) · Blood · doi:10.1182/blood-2008-06-165225 · Cited by 268 · see citing works

Radiofrequency Thermal Ablation of Hepatocellular Carcinoma Liver Nodules Can Activate and Enhance Tumor-Specific T-Cell Responses

Zerbini, A., Pilli, M., Penna, A., Pelosi, G., Schianchi, C., Molinari, A., Schivazappa, S., Zibera, C., Fagnoni, F. F., Ferrari, C. I., et al. (2006) · Cancer Research · doi:10.1158/0008-5472.can-05-2244 · Cited by 267 · see citing works

Bystander elimination of antigen loss variants in established tumors

Spiotto, M. T., Rowley, D. A., & Schreiber, H. W. (2004) · Nature Medicine · doi:10.1038/nm999 · Cited by 260 · see citing works

Evolutionary biology of cancer

Crespi, B. J., & Summers, K. (2005) · Trends in Ecology & Evolution · doi:10.1016/j.tree.2005.07.007 · Cited by 258 · see citing works

Eradication of established tumors in mice by a combination antibody-based therapy

Uno, T., Takeda, K., Kojima, Y., Yoshizawa, H., Akiba, H., Mittler, R. S., Gejyo, F., Okumura, K., Yagita∥, H., & Smyth, M. J. (2006) · Nature Medicine · doi:10.1038/nm1405 · Cited by 257 · see citing works

Sustained Type I interferon signaling as a mechanism of resistance to PD-1 blockade

Jacquelot, N., Yamazaki, T., Roberti, M. P., Duong, C. P. M., Andrews, M. C., Verlingue, L., Ferrere, G., Becharef, S., Vétizou, M., Daillère, R., et al. (2019) · Cell Research · doi:10.1038/s41422-019-0224-x · Cited by 256 · see citing works

Folate receptor-targeted immunotherapy of cancer: mechanism and therapeutic potential

Lu, Y. (2004) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2004.01.009 · Cited by 256 · see citing works

Immune Cell–Poor Melanomas Benefit from PD-1 Blockade after Targeted Type I IFN Activation

Bald, T., Landsberg, J., Lopez-Ramos, D., Renn, M., Glodde, N., Jansen, P., Gaffal, E., Steitz, J., Tolba, R. H., Kalinke, U., et al. (2014) · Cancer Discovery · doi:10.1158/2159-8290.cd-13-0458 · Cited by 256 · see citing works

The circadian clock in cancer development and therapy

Fu, L., & Kettner, N. M. (2013) · Progress in Molecular Biology and Translational Science · doi:10.1016/b978-0-12-396971-2.00009-9 · Cited by 251 · see citing works

Natural and Induced T Regulatory Cells in Cancer

Adeegbe, D. O., & Nishikawa, H. (2013) · Frontiers in Immunology · doi:10.3389/fimmu.2013.00190 · Cited by 248 · see citing works

Endogenous T Cell Responses to Antigens Expressed in Lung Adenocarcinomas Delay Malignant Tumor Progression

DuPage, M. J. P., Cheung, A. F., Mazumdar, C., Winslow, M. M., Bronson, R. T., Schmidt, L., Crowley, D. G., Chen, J., & Jacks, T. (2011) · Cancer Cell · doi:10.1016/j.ccr.2010.11.011 · Cited by 244 · see citing works

Host Factors and Cancer Progression: Biobehavioral Signaling Pathways and Interventions

Lutgendorf, S. K., Sood, A. K., & Antoni, M. H. (2010) · Journal of Clinical Oncology · doi:10.1200/jco.2009.26.9357 · Cited by 238 · see citing works

Cancer Immunotherapy: A Future Paradigm Shift in the Treatment of Non–Small Cell Lung Cancer

Anagnostou, V., & Brahmer, J. R. (2015) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-14-1187 · Cited by 236 · see citing works

High frequency of antitumor T cells in the blood of melanoma patients before and after vaccination with tumor antigens

Germeau, C., Ma, W., Schiavetti, F., Lurquin, C., Henry, E., Vigneron, N., Brasseur, F., Lethé, B., Plaen, E. D., Velu, T. J., et al. (2005) · The Journal of Experimental Medicine · doi:10.1084/jem.20041379 · Cited by 232 · see citing works

Adoptive immunotherapy of cancer using CD4+ T cells

Muranski, P. J., & Restifo, N. P. (2009) · Current Opinion in Immunology · doi:10.1016/j.coi.2009.02.004 · Cited by 219 · see citing works

Relapse after allogeneic stem cell transplantation

Barrett, A. J., & Battiwalla, M. (2010) · Expert Review of Hematology · doi:10.1586/ehm.10.32 · Cited by 212 · see citing works

Biobehavioral Factors and Cancer Progression

Lutgendorf, S. K., & Sood, A. K. (2011) · Psychosomatic Medicine · doi:10.1097/psy.0b013e318235be76 · Cited by 213 · see citing works

How Do CD4+ T Cells Detect and Eliminate Tumor Cells That Either Lack or Express MHC Class II Molecules?

Haabeth, O. A. W., Tveita, A. A., Fauskanger, M., Schjesvold, F. H., Lorvik, K. B., Hofgaard, P. O., Omholt, H., Munthe, L. A., Dembić, Z., Corthay, A., et al. (2014) · Frontiers in Immunology · doi:10.3389/fimmu.2014.00174 · Cited by 199 · see citing works

Tumors as elusive targets of T-cell-based active immunotherapy

Marincola, F. M., Wang, E., Herlyn, M., Seliger, B., & Ferrone, S. (2003) · Trends in Immunology · doi:10.1016/s1471-4906(03)00116-9 · Cited by 202 · see citing works

Intraepithelial CD8+ T-cell-count becomes a prognostic factor after a longer follow-up period in human colorectal carcinoma: possible association with suppression of micrometastasis

Chiba, T., Ohtani, H., Mizoi, T., Naito, Y., Sato, E., Nagura, H., Ohuchi, A., Ohuchi, K., Shiiba, K., Kurokawa, Y., et al. (2004) · British Journal of Cancer · doi:10.1038/sj.bjc.6602201 · Cited by 201 · see citing works

Acquired and intrinsic resistance in cancer immunotherapy

Kelderman, S., Schumacher, T. N. M., & Haanen, J. B. A. G. (2014) · Molecular Oncology · doi:10.1016/j.molonc.2014.07.011 · Cited by 197 · see citing works

Engineering antigen-specific primary human NK cells against HER-2 positive carcinomas

Kruschinski, A., Moosmann, A., Poschke, I. C., Norell, H., Chmielewski, M. M., Seliger, B., Kiessling, R. W., Blankenstein, T. J. F., Abken, H., & Charo, J. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0804788105 · Cited by 196 · see citing works

Paradoxical effects of cytokines in tumor immune surveillance and tumor immune escape

Salazar‐Onfray, F., López, M. N., & Mendoza‐Naranjo, A. (2007) · Cytokine & Growth Factor Reviews · doi:10.1016/j.cytogfr.2007.01.015 · Cited by 216 · see citing works

Part I: Vaccines for solid tumours

D, S. M. M., Mandruzzato, S., Bronte, V., Lise, M., & Nitti, D. (2004) · The Lancet Oncology · doi:10.1016/s1470-2045(04)01610-9 · Cited by 194 · see citing works

Roles of the immune system in skin cancer

Rangwala, S., & Tsai, K. Y. (2011) · British Journal of Dermatology · doi:10.1111/j.1365-2133.2011.10507.x · Cited by 188 · see citing works

High-Risk Ovarian Cancer Based on 126-Gene Expression Signature Is Uniquely Characterized by Downregulation of Antigen Presentation Pathway

Yoshihara, K., Tsunoda, T., Shigemizu, D., Fujiwara, H., Hatae, M., Fujiwara, H., Masuzaki, H., Katabuchi, H., Kawakami, Y., Okamoto, A., et al. (2012) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-11-2725 · Cited by 189 · see citing works

Biobehavioral Approaches to Cancer Progression and Survival

Lutgendorf, S., & Andersen, B. (2015) · American Psychologist · doi:10.1037/a0035730 · Cited by 176 · see citing works

Interplay between DNA repair and inflammation, and the link to cancer

Kidane, D., Chae, W. J., Czochor, J. R., Eckert, K. A., Glazer, P. M., Bothwell, A. L. M., & Sweasy, J. B. (2014) · Critical Reviews in Biochemistry and Molecular Biology · doi:10.3109/10409238.2013.875514 · Cited by 186 · see citing works

Curcumin reverses T cell-mediated adaptive immune dysfunctions in tumor-bearing hosts

Bhattacharyya, S., Hossain, D. M. S., Mohanty, S., Sen, G. S., Chattopadhyay, S., Banerjee, S., Chakraborty, J., Das, K., Sarkar, D. K., Das, T., et al. (2010) · Cellular and Molecular Immunology · doi:10.1038/cmi.2010.11 · Cited by 186 · see citing works

Targeting death-inducing receptors in cancer therapy

Takeda, K., Stagg, J., Yagita∥, H., Okumura, K., & Smyth, M. J. (2007) · Oncogene · doi:10.1038/sj.onc.1210374 · Cited by 184 · see citing works

Extracranial Oligometastases: A Subset of Metastases Curable With Stereotactic Radiotherapy

Corbin, K. S., Hellmän, S., & Weichselbaum, R. R. (2013) · Journal of Clinical Oncology · doi:10.1200/jco.2012.45.9651 · Cited by 185 · see citing works

Human Leukocyte Antigen and Antigen Processing Machinery Component Defects in Astrocytic Tumors

Facoetti, A., Nano, R., Zelini, P., Morbini, P., Benericetti, E., Ceroni, M., Campoli, M. R., & Ferrone, S. (2005) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-04-2588 · Cited by 184 · see citing works

Targeting microRNAs as key modulators of tumor immune response

Paladini, L., Fabris, L., Bottai, G., Raschioni, C., Călin, G. A., & Santarpia, L. (2016) · Journal of Experimental & Clinical Cancer Research · doi:10.1186/s13046-016-0375-2 · Cited by 183 · see citing works

Michor F: A race between tumor immunoescape and genome maintenance selects for optimum levels of (epi)genetic instability

Iwami, S., Haeno, H., & Franziska Michor, A. (2016)

A Race between Tumor Immunoescape and Genome Maintenance Selects for Optimum Levels of (epi)genetic Instability

Iwami, S., Haeno, H., & Franziska Michor, A. (2012) · PLoS Computational Biology · doi:10.1371/journal.pcbi.1002370 · Cited by 14 · see citing works

Immunotherapy and immunoselection ? tumour escape as the final hurdle

Pawelec, G. (2004) · FEBS Letters · doi:10.1016/j.febslet.2004.02.091 · Cited by 30 · see citing works

Strategies for tumor immune escape

Piemonti, L., Zerbi, A., & Carlo, V. D. (2003) · Drugs of today · doi:10.1358/dot.2003.39.9.799478 · Cited by 8 · see citing works

Abstract 4034: Immunotherapy generates selective pressure to create an escape tumor with increased susceptibility to treatment with T cell based therapies

Pan, J. H., Vodnala, S. K., Eil, R. L., Yu, Z., Gartner, J. J., Clever, D. C., Roychoudhuri, R., Patel, S. J., Klebanoff, C. A., Sukumar, M., et al. (2016) · Cancer Research · doi:10.1158/1538-7445.am2016-4034