Circulating fetuin-A and free fatty acids interact to predict insulin resistance in humans
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Fetuin A engages TLR-4 in adipocytes and macrophages to promote proinflammatory activation, in conjunction with FFAs.
“Fetuin A engages TLR-4 in adipocytes and Mφ to promote proinflammatory activation, in conjunction with FFAs [187,188].”
Cites
Fetuin-A acts as an endogenous ligand of TLR4 to promote lipid-induced insulin resistance
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- Authors
- Stefan, N., & Häring, H.-U.
- Affiliations
- German Center for Diabetes Research (DE)
- Corresponding author
- Stefan, Norbert
- Venue
- Nature Medicine
- Published
- 2013-04
- Volume
- 19
- Issue
- 4
- Pages
- 394-395
- ISSN
- 1078-8956 (ISSN-L)
- 1546-170X
- OpenAlex
- W2078349405
- Cited by
- 160
- References
- 9
- Citations by year
- 2026: 9 · 2025: 6 · 2024: 8 · 2023: 8 · 2022: 4 · 2021: 12 · 2020: 11 · 2019: 13 · 2018: 12 · 2017: 26 · 2016: 16 · 2015: 9 · 2014: 19 · 2013: 7
- FWCI
- 12.34
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Nature Medicine (publishedVersion)
- PubMed (publishedVersion)
- Site cant be reached (submittedVersion)
- Topics
- Health Sciences › Medicine › Epidemiology › Adipokines, Inflammation, and Metabolic Diseases
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes, Cardiovascular Risks, and Lipoproteins
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Disease and Adiposity
- Keywords
- fetuin-A, free fatty acids, insulin resistance, circulating biomarkers, type 2 diabetes, adipose tissue insulin resistance, coronary artery calcification
- MeSH terms
- Cardiovascular Diseases, Diabetes Mellitus, Type 2, Fatty Acids, Nonesterified, Humans, Insulin Resistance, Risk Factors, alpha-2-HS-Glycoprotein
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