Mutational landscape of metastatic cancer revealed from prospective clinical sequencing of 10,000 patients

Zehir, Ahmet, Benayed, Ryma, Shah, Ronak H, Syed, Aijazuddin, Middha, Sumit, Kim, Hyunjae R, Srinivasan, Preethi, Gao, Jianjiong +92 more·2017·Nature Medicine

DOI 10.1038/nm.4333

Cited by (1,010)

Items 501–600 of 1,010

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RAS as Supporting Actor in Breast Cancer
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Phase II study of atezolizumab in combination with bevacizumab in patients with advanced cervical cancer
Claire Frances Friedman, Alexandra Snyder, Qin C Zhou, Michael Anthony Carducci, Alexandre Buckley de Meritens, Bradley R. Corr, Siqing Fu, Travis J. Hollmann, Alexia E. Iasonos, Jason A. Konner et al. · 2020 · Journal for ImmunoTherapy of Cancer
The Predictive Value of Tumor Mutation Burden on Clinical Efficacy of Immune Checkpoint Inhibitors in Melanoma: A Systematic Review and Meta-Analysis
Biao Ning, Yixin Liu, Miao Wang, Yi Li, Tianzi Xu, Yongchang Wei · 2022 · Frontiers in Pharmacology
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Timothy Nguyen Clinton, Ziyu Chen, Hannah C. Wise, Andrew Thomas Lenis, Shweta S. Chavan, Mark T.A. Donoghue, Nima Almassi, Carissa Ellen Chu, Shawn Dason, Pavitra Rao et al. · 2022 · Cell Reports
The emerging role of PI3K inhibitors for solid tumour treatment and beyond
Carmen Belli, Matteo Repetto, Santosh Kumar Anand, Camillo Porta, Vivek Subbiah, Giuseppe Curigliano · 2023 · British Journal of Cancer
The Future of Precision Oncology
Stuart L. Rulten, Richard Philip Grose, Susanne A. Gatz, J. Louise Jones, Angus J.M. Cameron · 2023 · International Journal of Molecular Sciences
Enzalutamide therapy for advanced prostate cancer: efficacy, resistance and beyond
Simon Linder, Henk G. van der Poel, Andries Marinus Bergman, Wilbert T. Zwart, Stefan Preković · 2018 · Endocrine Related Cancer
Targeting Krasg12c‐mutant cancer with a mutation‐specific inhibitor
James G. Christensen, Peter Olson, T. Briere, Clotilde Wiel, Martin O. Bergö · 2020 · Journal of Internal Medicine
Mammalian SWI/SNF Complex Genomic Alterations and Immune Checkpoint Blockade in Solid Tumors
Sarah Abou Alaiwi, Amin H. Nassar, Wanling Xie, Ziad Bakouny, Jacob E. Berchuck, David A. Braun, Sylvan C. Baca, Pier Vitale Nuzzo, Ronan Flippot, Tarek H. Mouhieddine et al. · 2020 · Cancer Immunology Research
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Aishwarya Kulkarni, Matthew T. Chang, Joseph H.A. Vissers, Anwesha Dey, Kieran F. Harvey · 2020 · Trends in cancer
Rational development of combination therapies for biliary tract cancers
James J. Harding, Danny N. Khalil, Luca Fabris, Ghassan K. Abou‐Alfa · 2022 · Journal of Hepatology
High-Throughput Functional Evaluation of Variants of Unknown Significance in ERBB2
Masaaki Nagano, Shinji Kohsaka, Toshihide Ueno, Shinya Kojima, Kanju Saka, Hirotaro Iwase, Masahito Kawazu, Hiroyuki Mano · 2018 · Clinical Cancer Research
Mutations of p53 associated with pancreatic cancer and therapeutic implications
Voutsadakis, Ioannis A. · 2021 · Annals of Hepato-Biliary-Pancreatic Surgery
Alveolar Differentiation Drives Resistance to <i>KRAS</i> Inhibition in Lung Adenocarcinoma
Li, Zhuxuan, Zhuang, Xueqian, Pan, Chun-Hao, Yan, Yan, Thummalapalli, Rohit, Hallin, Jill, Torborg, Stefan, Singhal, Anupriya, Chang, Jason C., Manchado, Eusebio et al. · 2024 · Cancer Discovery
The role of poly(ADP-ribose) polymerase inhibitors in the treatment of cancer and methods to overcome resistance: a review
Mausam A. Patel, Somaira Nowsheen, Sanjay Maraboyina, Fen Xia · 2020 · Cell & Bioscience
Alterations in driver genes are predictive of survival in patients with resected pancreatic ductal adenocarcinoma
Caitlin A. McIntyre, Sharon Lawrence, Allison L. Richards, Joanne F. Chou, Winston Wong, Marinela Capanu, Michael F. Berger, Mark T.A. Donoghue, Kenneth H. Yu, Anna M. Varghese et al. · 2020 · Cancer
Comprehensive Genomic Profiling of Carcinoma of Unknown Primary Origin: Retrospective Molecular Classification Considering the CUPISCO Study Design
Jeffrey S. Ross, Ethan S. Sokol, Holger Moch, Linda Mileshkin, Giulia Baciarello, Ferrán Losa, Andreas Beringer, Marlène Thomas, Julia Andrea Elvin, Nhu Ngo et al. · 2020 · The Oncologist
Feasibility of whole genome and transcriptome profiling in pediatric and young adult cancers
Neerav Narendra Shukla, Max Fine Levine, Gunes Gundem, Dylan Domenico, Barbara G. Spitzer, Nancy Bouvier, Juan Arango Ossa, Dominik Głodzik, Juan Santiago Medina-Martinez, Umesh Kumar Bhanot et al. · 2022 · Nature Communications
PD-1/PD-L1 Axis in Lung Cancer
Fernando Costa Santini, Matthew David Hellmann · 2018 · The Cancer Journal
Identification of Hypermutation and Defective Mismatch Repair in ctDNA from Metastatic Prostate Cancer
Elie J. Ritch, Simon Yuen Fai Fu, Cameron Herberts, Gang Wang, Evan W. Warner, Elena Schönlau, Sinja Taavitsainen, Andrew J. Murtha, Gillian Rae Vandekerkhove, Kevin Beja et al. · 2019 · Clinical Cancer Research
Significantly greater prevalence of DICER1 alterations in uterine embryonal rhabdomyosarcoma compared to adenosarcoma
Leanne de Kock, Ju‐Yoon Yoon, María Apellániz-Ruiz, Dylan Pelletier, Wilson Glenn McCluggage, Colin J.R. Stewart, Brendan Craig Dickson, Marjan Rouzbahman, Blaise Alexander Clarke, William David Foulkes · 2020 · Modern Pathology
“Metastatic Cancer of Unknown Primary” or “Primary Metastatic Cancer”?
Stefan Kolling, Ferdinando Ventre, Elena Geuna, Melissa Milan, Alberto Maria Pisacane, Carla Boccaccio, Anna Sapino, Filippo Montemurro · 2020 · Frontiers in Oncology
BRAF-Mutated Non-Small Cell Lung Cancer: Current Treatment Status and Future Perspective
Ningning Yan, Sanxing Guo, Huixian Zhang, Ziheng Zhang, Shujing Shen, Xingya Li · 2022 · Frontiers in Oncology
High-throughput evaluation of genetic variants with prime editing sensor libraries
Samuel I. Gould, Alexandra N. Wuest, Kexin Dong, Grace A. Johnson, Alvin Hsu, Varun K. Narendra, Ondine Atwa, Stuart S. Levine, David R. Liu, Francisco J. Sánchez Rivera · 2024 · Nature Biotechnology
Polycomb/Trithorax Antagonism: Cellular Memory in Stem Cell Fate and Function
Marjorie Brand, Kiran Kumar Nakka, Jiayu Zhu, Francis Jeffrey Dilworth · 2019 · Cell stem cell
The Function of RAS Mutation in Cancer and Advances in its Drug Research
Shijie Chen, Fengyang Li, Dan Xu, Kai Hou, Weirong Fang, Yunman Li · 2019 · Current Pharmaceutical Design
Phase 2 study of LY3023414 in patients with advanced endometrial cancer harboring activating mutations in the PI3K pathway
Maria M Zlobinsky Rubinstein, David Michael Hyman, Imogen Caird, Helen H. Won, Krysten Soldan, Kenneth Seier, Alexia E. Iasonos, William P. Tew, Roisin Eilish O'Cearbhaill, Rachel Nicole Grisham et al. · 2019 · Cancer
DNA Repair Gene Mutations as Predictors of Immune Checkpoint Inhibitor Response beyond Tumor Mutation Burden
David Hsiehchen, Antony Hsieh, Robert M. Samstein, Tianshi Lu, Muhammad Shaalan Beg, David E. Gerber, Tao Wang, Luc G.T. Morris, Hao Zhu · 2020 · Cell Reports Medicine
Safety, Antitumor Activity, and Biomarker Analysis in a Phase I Trial of the Once-daily Wee1 Inhibitor Adavosertib (AZD1775) in Patients with Advanced Solid Tumors
Naoko Takebe, Abdul Rafeh Naqash, Geraldine O’Sullivan Coyne, Shivaani Kummar, Khanh T Do, Ashley B. Bruns, Lamin Juwara, Jennifer Zlott, Larry Rubinstein, Richard Piekarz et al. · 2021 · Clinical Cancer Research
Clinical utility of whole-genome sequencing in precision oncology
Richard Rosenquist, Edwin P. J. G. Cuppen, Reinhard Buettner, Carlos Caldas, Helene Marie-Pierre Dreau, Olivier Elemento, Geert Frederix, Sean Michael Grimmond, Torsten Haferlach, Vaidehi Jobanputra et al. · 2021 · Seminars in Cancer Biology
Hepatocellular Carcinoma: A Comprehensive Review
Nisar A. Amin, Javaria Anwar, Abdullahi Adedotun Sulaiman, Nataliia Naumova, Nadeem Anwar · 2025 · Diseases
Neratinib is effective in breast tumors bearing both amplification and mutation of ERBB2 (HER2)
Emiliano Cocco, F. Javier Carmona, Pedram Razavi, Helen H. Won, Yanyan Cai, Valentina Rossi, Carmen Chan, James Cownie, Joanne Soong, Eneda Toska et al. · 2018 · Science Signaling
Molecular Landscape of BRAF-Mutant NSCLC Reveals an Association Between Clonality and Driver Mutations and Identifies Targetable Non-V600 Driver Mutations
Marcelo Vailati Negrao, Victoria M. Raymond, Richard Burnham Lanman, Jacqulyne Ponville Robichaux, Junqin He, Monique B. Nilsson, Patrick Kwok‐Shing Ng, Bianca E. Amador, Emily B. Roarty, Rebecca J. Nagy et al. · 2020 · Journal of Thoracic Oncology
Targeted Therapies for Pancreatic Cancer: Overview of Current Treatments and New Opportunities for Personalized Oncology
Cédric Leroux, Georgia Konstantinidou · 2021 · Cancers
Hepatocellular Carcinoma: Molecular Pathogenesis and Therapeutic Advances
Blanca Cucarull, Anna Tutusaus, Patricia Rider, Tania Hernáez-Alsina, Carlos Cuño-Gómiz, Pablo Garcı́a de Frutos, Anna Colell, Montserrat Marı́, Albert Morales · 2022 · Cancers
Integrative analysis of multi-omics data for liquid biopsy
Geng Chen, Jing Zhang, Qiaoting Fu, Valérie Taly, Fei Tan · 2022 · British Journal of Cancer
Microsatellite instability, tumor mutational burden, and response to immune checkpoint blockade in patients with prostate cancer
Lenis, Andrew T., Ravichandran, Vignesh, Brown, Samantha, Alam, Syed M., Katims, Andrew, Truong, Hong, Reisz, Peter A., Vasselman, Samantha, Nweji, Barbara, Autio, Karen A. et al. · 2024 · Clinical Cancer Research
KRAS G12D mutation predicts lower TMB and drives immune suppression in lung adenocarcinoma
Gao, Ge, Liao, Weiting, Ma, Qizhi, Zhang, Benxia, Chen, Yue, Wang, Yongsheng · 2020 · Lung Cancer
Development of new preclinical models to advance adrenocortical carcinoma research
Katja Kiseljak‐Vassiliades, Yu Zhang, Stacey M. Bagby, Adwitiya Kar, Nikita V. Pozdeyev, Mei Xu, Katherine Gowan, Vibha Sharma, Christopher D. Raeburn, Maria B. Albuja-Cruz et al. · 2018 · Endocrine Related Cancer
JAK2/PD-L1/PD-L2 (9p24.1) amplifications in renal cell carcinomas with sarcomatoid transformation: implications for clinical management
Sounak Gupta, John C. Cheville, Achim A. Jungbluth, Yanming Zhang, Lei Zhang, Ying‐Bei Chen, Satish K. Tickoo, Samson W. Fine, Anuradha Gopalan, Hikmat A Al‐Ahmadie et al. · 2019 · Modern Pathology
Clinical outcomes of patients with POLE mutated endometrioid endometrial cancer
Marina Stasenko, Irina Tunnage, Charles W. Ashley, Maria M Zlobinsky Rubinstein, Alicia J. Latham, Arnaud Da Cruz Paula, Jennifer Jean Mueller, Mario M. Leitão, Claire Frances Friedman, Vicky Makker et al. · 2019 · Gynecologic Oncology
Neratinib in patients with HER2-mutant, metastatic cervical cancer: Findings from the phase 2 SUMMIT basket trial
Ana Oaknin, Claire Frances Friedman, Lynda D. Roman, Anishka D'souza, Irene Braña, François‐Clément Bidard, Jonathan Wade Goldman, Edwin Alexander Alvarez, Valentina Boni, Adam C. ElNaggar et al. · 2020 · Gynecologic Oncology
The contributions of cancer cell metabolism to metastasis
Gloria Pascual, Diana Domínguez, Salvador Aznar Benitah · 2018 · Disease Models & Mechanisms
Analysis of 10,478 cancer genomes identifies candidate driver genes and opportunities for precision oncology
Kinnersley, Ben, Sud, Amit, Everall, Andrew, Cornish, Alex J., Chubb, Daniel, Culliford, Richard, Gruber, Andreas J., Lärkeryd, Adrian, Mitsopoulos, Costas, Wedge, David et al. · 2024 · Nature Genetics
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Chey Loveday, Kevin Litchfield, Paula Proszek, Alex J. Cornish, Flavia Matos Santo, Max Levy, Geoff Macintyre, Amy Holryod, Peter Broderick, Darshna Dudakia et al. · 2020 · Nature Communications
Machine learning-based prediction of microsatellite instability and high tumor mutation burden from contrast-enhanced computed tomography in endometrial cancers
H. Veeraraghavan, C. Friedman, D. DeLair, J. Nincevic, Y. Himoto, S. Bruni, G. Cappello, I. Petkovska, S. Nougaret, I. Nikolovski et al. · 2020 · Scientific Reports
Molecular landscape and efficacy of HER2-targeted therapy in patients with HER2-mutated metastatic breast cancer
Zongbi Yi, Guohua Rong, Yanfang Guan, Jin Li, Lianpeng Chang, Hui Li, Binliang Liu, Wenna Wang, Xiuwen Guan, Quchang Ouyang et al. · 2020 · npj Breast Cancer
A pan-cancer analysis of HER2 index revealed transcriptional pattern for precise selection of HER2-targeted therapy
Ziteng Li, Siyuan Chen, Wanjing Feng, Yixiao Luo, Hongyan Lai, Qin Li, Bingqiu Xiu, Yuchen Li, Yan Li, Shenglin Huang et al. · 2020 · EBioMedicine
Loss of Smad4 promotes aggressive lung cancer metastasis by de-repression of PAK3 via miRNA regulation
Xiaohong Tan, Tong Lu, Lin Li, Jinjin Xu, Shaofang Xie, Lei Ji, Junjiang Fu, Qingwu Liu, Shihui Shen, Yun Liu et al. · 2021 · Nature Communications
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Beryl L. Manning‐Geist, Ying L. Liu, Kelly A. Devereaux, Arnaud Da Cruz Paula, Qin C Zhou, Weining Ma, Pier Selenica, Ozge Ceyhan‐Birsoy, Lea A. Moukarzel, Timothy J. Hoang et al. · 2022 · Clinical Cancer Research
Machine Learning and Radiogenomics: Lessons Learned and Future Directions
John Kang, T. Rancati, Sangkyu Lee, Jung Hun Oh, Sarah L. Kerns, Jacob G. Scott, Russell S. Schwartz, Se Young Kim, Barry S. Rosenstein · 2018 · Frontiers in Oncology
Personalized cancer therapy—leveraging a knowledge base for clinical decision-making
Ecaterina Ileana Dumbrava, Funda Meric‐Bernstam · 2017 · Molecular Case Studies
Intratumor heterogeneity comparison among different subtypes of non-small-cell lung cancer through multi-region tissue and matched ctDNA sequencing
Yaxiong Zhang, Lianpeng Chang, Yunpeng Yang, Wenfeng Fang, Yanfang Guan, Aiwei Wu, Shaodong Hong, Huaqiang Zhou, Gang Chen, Xi Chen et al. · 2019 · Molecular Cancer
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Kevin M. Levine, Nolan Priedigkeit, Ahmed Basudan, Nilgun Tasdemir, Matthew J. Sikora, Ethan S. Sokol, Ryan James Hartmaier, Kai Ding, Nedah Z. Ahmad, Rebecca Jean Watters et al. · 2019 · npj Breast Cancer
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Yusuke Tsuda, Lei Zhang, Paul A. Meyers, William D. Tap, John H. Healey, Cristina R. Antonescu · 2020 · Genes Chromosomes and Cancer
BRG1 Loss Predisposes Lung Cancers to Replicative Stress and ATR Dependency
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Saba Ubaid, Rashmi Kushwaha, Mohammad Kashif, Vivek Kumar Singh · 2025 · Cancer Genetics
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Shinji Kohsaka, Kenji Tatsuno, Toshihide Ueno, Masaaki Nagano, Aya Shinozaki‐Ushiku, Tetsuo Ushiku, Daiya Takai, Masachika Ikegami, Hiroshi Kobayashi, Hidenori Kage et al. · 2019 · Cancer Science
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Kenneth L. Pitter, Dana L. Casey, Yue Christine Lu, Margaret Hannum, Zhigang Zhang, Xinmao Song, Isabella L. Pecorari, Biko McMillan, Jennifer Ma, Robert M. Samstein et al. · 2020 · JNCI Journal of the National Cancer Institute
Novel patient-derived preclinical models of liver cancer
Erin R. Bresnahan, Pierluigi Ramadori, Mathias F Heikenwälder, Lars Zender, Amaia Lujambio · 2020 · Journal of Hepatology
Biomarkers in melanoma and non‐melanoma skin cancer prevention and risk stratification
Megan H. Trager, Larisa J. Geskin, Faramarz H. Samie, Liang Liu · 2020 · Experimental Dermatology
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Neil T. Conlon, Jeffrey J. Kooijman, Suzanne J.C. van Gerwen, Winfried R. Mulder, Guido J.R. Zaman, Irmina Diala, Lisa D. Eli, Alshad S. Lalani, John Paul Crown, Denis Martin Collins · 2021 · British Journal of Cancer
The proprotein convertase furin in cancer: more than an oncogene
Zongsheng He, Abdel‐Majid Khatib, John W.M. Creemers · 2022 · Oncogene
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Michael Friedrich, Simon Jasinski‐Bergner, Maria‐Filothei Lazaridou, Karthikeyan Subbarayan, Chiara Massa, Sandy Tretbar, Anja Müeller, Diana Handke, Katharina Biehl, Jürgen Bukur et al. · 2019 · Cancer Immunology Immunotherapy
Biphasic Hyalinizing Psammomatous Renal Cell Carcinoma (BHP RCC)
Pedram Argani, Victor E. Reuter, John N. Eble, Ljiljana Vlatkovic, Oksana Yaskiv, David Michael Swanson, Brendan Craig Dickson, Cristina R. Antonescu, Andrés Matoso, Jeffrey Gagan et al. · 2020 · The American Journal of Surgical Pathology
Notch activity characterizes a common hepatocellular carcinoma subtype with unique molecular and clinicopathologic features
Changyu Zhu, Yu-Jui Ho, Marcela A. Salomao, Dianne H. Dapito, Alberto Bartolomé, Robert F. Schwabe, Ju‐Seog Lee, Scott W. Lowe, Utpal B. Pajvani · 2020 · Journal of Hepatology
ARID1A, ARID1B, and ARID2 Mutations Serve as Potential Biomarkers for Immune Checkpoint Blockade in Patients With Non-Small Cell Lung Cancer
Guangsheng Zhu, Ruifeng Shi, Li Y, Zihe Zhang, Songlin Xu, Chen Chen, Peijun Cao, Hongbing Zhang, Minghui Liu, Zhenhua Pan et al. · 2021 · Frontiers in Immunology
S6K1-mediated phosphorylation of PDK1 impairs AKT kinase activity and oncogenic functions
Qiwei Jiang, Xiaomei Zhang, Xiaoming Dai, Shiyao Han, Xueji Wu, Lei Wang, Wenyi Wei, Ning Zhang, Wei Xie, Jianping Guo · 2022 · Nature Communications
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Oleksii S. Rukhlenko, Fahimeh Khorsand, Aleksandar Krstić, Jan Rožanc, Leonidas G. Alexopoulos, Nora Rauch, Keesha E. Erickson, William S. Hlavacek, Richard G. Posner, Silvia Gómez‐Coca et al. · 2018 · Cell Systems
Parallel Analyses of Somatic Mutations in Plasma Circulating Tumor DNA (ctDNA) and Matched Tumor Tissues in Early-Stage Breast Cancer
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Update on biology and management of mesothelioma
Asciak, Rachelle, George, Vineeth, Rahman, Najiib M. · 2021 · European Respiratory Review
In perspective: An update on telomere targeting in cancer
Eric T. Sugarman, Gao Zhang, Jerry W. Shay · 2019 · Molecular Carcinogenesis
Liquid biopsy for mutational profiling of locoregional recurrent and/or metastatic head and neck squamous cell carcinoma
Rachel Galot, Cédric van Marcke, Raphaël Helaers, Antonella Mendola, Rose‐Marie Goebbels, Xavier Caignet, Jérôme Ambroise, Kyril Wittouck, Miikka Vikkula, Nisha Limaye et al. · 2020 · Oral Oncology
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Zhenfang Du, Benjamin P. Brown, Soyeon Kim, Donna C. Ferguson, Dean C. Pavlick, Gowtham Jayakumaran, Ryma Benayed, Jean‐Nicolas Gallant, Yunkai Zhang, Yingjun Yan et al. · 2021 · Nature Communications
Identification of NOTCH4 mutation as a response biomarker for immune checkpoint inhibitor therapy
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Acquired Resistance of MET-Amplified Non-small Cell Lung Cancer Cells to the MET Inhibitor Capmatinib
Seulki Kim, Tae Min Kim, Dong‐Wan Kim, Soyeon Kim, Miso Kim, Yong‐Oon Ahn, Bhumsuk Keam, Dae Seog Heo · 2018 · Cancer Research and Treatment
Pan-cancer analysis of KEAP1 mutations as biomarkers for immunotherapy outcomes
Xiaoxia Chen, Chunxia Su, Shengxiang Ren, Caicun Zhou, Tao Jiang · 2020 · Annals of Translational Medicine
Cyclin-Dependent Kinase 12, Immunity, and Prostate Cancer
Emmanuel S. Antonarakis · 2018 · New England Journal of Medicine
Cancer of Unknown Primary: Challenges and Progress in Clinical Management
Noemi Laprovitera, Mattia Riefolo, Elisa Ambrosini, Christiane Klec, Martin Pichler, Manuela Ferracin · 2021 · Cancers
Selective multiplexed enrichment for the detection and quantitation of low-fraction DNA variants via low-depth sequencing
Ping Song, Sherry Xi Chen, Yan Helen Yan, Alessandro Pinto, Lauren Yuxuan Cheng, Peng Dai, Abhijit A. Patel, David Yu Zhang · 2021 · Nature Biomedical Engineering
Molecular Classification of Appendiceal Adenocarcinoma
Michael Bonner Foote, Henry S. Walch, Walid Khaled Chatila, Efsevia Vakiani, Chris Chandler, Felix Steinruecke, Garrett Michael Nash, Zsofia Kinga Stadler, Sebastian K. Chung, Rona D. Yaeger et al. · 2022 · Journal of Clinical Oncology
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Manuel Jorge Rodrigues, Lenha Mobuchon, Alexandre Houy, Samar Alsafadi, Sylvain Baulande, Odette Mariani, Benjamin Marande, Khadija Aït Raïs, Monique K. van der Kooij, Ellen Kapiteijn et al. · 2019 · Clinical Cancer Research
Molecular Markers Guiding Thyroid Cancer Management
Carolina Nylén, Robert Mechera, Isabella Maréchal-Ross, Venessa Tsang, Angela S. Y. Chou, Anthony James Gill, Roderick John Clifton-Bligh, Bruce G. Robinson, Mark S. Sywak, Stan B. Sidhu et al. · 2020 · Cancers
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Bioinformatics Analysis for Circulating Cell-Free DNA in Cancer
Chiang‐Ching Huang, Meijun Du, Liang Wang · 2019 · Cancers
Genomic profiling of primary and recurrent adult granulosa cell tumors of the ovary
Arnaud Da Cruz Paula, Edaise M. da Silva, Sheila E. Segura, Fresia G. Pareja, Rui Bi, Pier Selenica, Sarah H. Kim, Lorenzo Ferrando, Mahsa Vahdatinia, Robert A. Soslow et al. · 2020 · Modern Pathology
Isabl Platform, a digital biobank for processing multimodal patient data
Juan Santiago Medina-Martinez, Juan Arango Ossa, Max Fine Levine, Yangyu Zhou, Gunes Gundem, Andrew L. Kung, Elli Papaemmanuil · 2020 · BMC Bioinformatics
The Landscape of PIK3CA Mutations in Colorectal Cancer
Ioannis A. Voutsadakis · 2021 · Clinical Colorectal Cancer
Clinical Experience of Cerebrospinal Fluid–Based Liquid Biopsy Demonstrates Superiority of Cell-Free DNA over Cell Pellet Genomic DNA for Molecular Profiling
Tejus Bale, Soo‐Ryum Yang, James P. Solomon, Khédoudja Nafa, Sumit Middha, Jacklyn Casanova, Justyna Sadowska, Anna Skakodub, Hamza Ahmad, Helena Alexandra Yu et al. · 2021 · Journal of Molecular Diagnostics
Positive Association Between Location of Melanoma, Ultraviolet Signature, Tumor Mutational Burden, and Response to Anti–PD-1 Therapy
L. Dousset, F. Poizeau, Caroline Robert, Sandrine Mansard, Laurent Mortier, Charline Caumont, Émilie Routier, Alain Dupuy, Jacques Rouanet, Maxime Battistella et al. · 2021 · JCO Precision Oncology
Current Status, Issues and Future Prospects of Personalized Medicine for Each Disease
Yuichi Yamamoto, Norihiro Kanayama, Yusuke Nakayama, Nobuko Matsushima · 2022 · Journal of Personalized Medicine
Genomic landscape of 891 RET fusions detected across diverse solid tumor types
Vamsi Parimi, Khaled A. Tolba, Natalie A. Danziger, Zheng Kuang, Daokun Sun, Douglas I. Lin, Matthew Hiemenz, Alexa Betzig Schrock, Jeffrey S. Ross, Geoffrey R. Oxnard et al. · 2023 · npj Precision Oncology