Mutational landscape of metastatic cancer revealed from prospective clinical sequencing of 10,000 patients

Zehir, Ahmet, Benayed, Ryma, Shah, Ronak H, Syed, Aijazuddin, Middha, Sumit, Kim, Hyunjae R, Srinivasan, Preethi, Gao, Jianjiong +92 more·2017·Nature Medicine

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  4. KRAS Alleles: The Devil Is in the Detail
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  15. Targeting an RNA-Binding Protein Network in Acute Myeloid Leukemia
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  16. Tumor Mutation Burden and Efficacy of EGFR-Tyrosine Kinase Inhibitors in Patients with EGFR -Mutant Lung Cancers
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  18. Ovarian cancer mutational processes drive site-specific immune evasion
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  20. SMARCA4-Deficient Thoracic Sarcomatoid Tumors Represent Primarily Smoking-Related Undifferentiated Carcinomas Rather Than Primary Thoracic Sarcomas
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  33. Immunogenomic profiling determines responses to combined PARP and PD-1 inhibition in ovarian cancer
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  35. TRK inhibitors in TRK fusion-positive cancers
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  44. Therapeutic Targeting of RNA Splicing Catalysis through Inhibition of Protein Arginine Methylation
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