Berberine is a novel cholesterol-lowering drug working through a unique mechanism distinct from statins

Kong, Weijia, Wei, Jing, Abidi, Parveen, Lin, Meihong, Inaba, Satoru, Li, Cong, Wang, Yanling, Wang, Zizheng +8 more·2004·Nature Medicine

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  1. Flavonoids activating adenosine monophosphate-activated protein kinase
    Yeonjoong Yong, Soon Young Shin, Yearam Jung, Hyeryoung Jung, Seunghyun Ahn, Youhoon Chong, Yoongho Lim · 2015 · Journal of the Korean Society for Applied Biological Chemistry
  2. JinqiJiangtang tablets for pre-diabetes: A randomized, double-blind and placebo-controlled clinical trial
    Hui Wang, Liping Guo, Hongcai Shang, Ming Ren, Xuemei Wang, Dehui Wang, Jianzong Chen, Shuanglei Li, Liming Chen, Yue Wang et al. · 2017 · Scientific Reports
  3. Berberine protects the liver and kidney against functional disorders and histological damages induced by ferrous sulfate.
    Firouzeh Gholampour, Samaneh Keikha · 2018 · Europe PMC (PubMed Central)
  4. Therapeutic Effects of Berberine in Metabolic Diseases and Diabetes Mellitus
    Khashayar Aram, Zahra Bahari, Moradipour Elliyeh, Maedeh Ghasemi · 2021 · Revista Brasileira de Farmacognosia
  5. Bacteroides fragilis-derived succinic acid promotes the degradation of uric acid by inhibiting hepatic AMPD2: Insight into how plant-based berberine ameliorates hyperuricemia
    Li‐Bin Pan, Ru Feng, Jiachun Hu, Hang Yu, Qian Tong, Xinyu Yang, Jian‐Ye Song, Hui Xiong Xu, Mengliang Ye, Zhengwei Zhang et al. · 2025 · Acta Pharmaceutica Sinica B
  6. Phytochemistry and pharmacology of alkaloids from Papaver spp.: a structure–activity based study
    Shekoufeh Aalinezhad, Farid Dabaghian, Aida Namdari, Maryam Akaberi, Seyed Ahmad Emami · 2024 · Phytochemistry Reviews
  7. Berberine cooperates with adrenal androgen dehydroepiandrosterone sulfate to attenuate PDGF-induced proliferation of vascular smooth muscle cell A7r5 through Skp2 signaling pathway
    Jia Liu, Jian Xiu, Junxian Cao, Qianping Gao, Dan Ma, Lu Fu · 2011 · Molecular and Cellular Biochemistry
  8. The auxiliary determination of the binding site of berberine binding to human serum albumin by surface-enhanced Raman scattering
    Wei Zhang, Yu Zhao, Xueyuan Bai, Ge Hui, John R. Lombardi, Daqing Zhao, Bing Zhao · 2010 · Vibrational Spectroscopy
  9. Anti-hyperlipidemic effects of Rhizoma Coptidis alkaloids are achieved through modulation of the enterohepatic circulation of bile acids and cross-talk between the gut microbiota and the liver
    Kai He, Hang Ma, Heshan Xu, Zongyao Zou, Min Feng, Xuegang Li, Xiaoli Ye · 2017 · Journal of Functional Foods
  10. Protein kinase C is involved in the neuroprotective effect of berberine against intrastriatal injection of quinolinic acid‐induced biochemical alteration in mice
    Peng Liu, Yinjie Li, Xiaoxiao Qi, Jia Feng Xu, Danyang Liu, Xuefei Ji, Tianyan Chi, Han Liu, Libo Zou · 2019 · Journal of Cellular and Molecular Medicine
  11. Cholesterol-Lowering Action of a Novel Nutraceutical Combination in Uremic Rats: Insights into the Molecular Mechanism in a Hepatoma Cell Line
    Maria Giovanna Lupo, Noemi Biancorosso, Elisa Brilli, Germano Tarantino, Maria Pia Adorni, Greta Vivian, Marika Salvalaio, Stefano Dall’Acqua, Stefania Sut, Cedric H. G. Neutel et al. · 2020 · Nutrients
  12. Covalent Modification of Proteins by Plant‐Derived Natural Products: Proteomic Approaches and Biological Impacts
    Restituto Tocmo, Jacob P. Veenstra, Yunying Huang, Jeremy James Johnson · 2020 · PROTEOMICS
  13. Design of Experiment Approach Based Formulation Optimization of Berberine Loaded Solid Lipid Nanoparticle for Antihyperlipidemic Activity
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  14. The Effect of Berberine on Lipid Profile, Liver Enzymes, and Fasting Blood Glucose in Patients with Non-alcoholic Fatty Liver Disease (NAFLD): A Randomized Controlled Trial
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  15. Progress of research in treatment of hyperlipidemia by monomer or compound recipe of Chinese herbal medicine
    Xiaobing Dou, WO Xing-de, Chunlei Fan · 2008 · Chinese Journal of Integrative Medicine
  16. Innovative cultivation: Hydroponics of medicinal plants in the closed-type cultivation facilities
    Kayo Yoshimatsu · 2012 · 和漢医薬学雑誌
  17. Synthesis and antihyperlipidemic efficiency of berberine-based HMG-CoA reductase inhibitor
    Xiaoli Ye, Kai He, Xiaokang Zhu, Baoshun Zhang, Xin Chen, Jun Yi, Xuegang Li · 2011 · Medicinal Chemistry Research
  18. Preparative separation of quaternary ammonium alkaloids from Corydalis yanhusuo W. T. Wang by pH‐zone‐refining counter‐current chromatography
    Qing Yu, Shengqiang Tong, Jizhong Yan, Chaoqun Hong, Wenfeng Zhai, Yaqin Li · 2011 · Journal of Separation Science
  19. 11-Hydroxylation of Protoberberine by the Novel Berberine-Utilizing Aerobic Bacterium Sphingobium sp. Strain BD3100
    Hisashi Takeda, Kazuki Ishikawa, Daigo Wakana, Masao Fukuda, Fumihiko Sato, Tomoo Hosoe · 2015 · Journal of Natural Products
  20. Cucumis melo ssp. Agrestis var. AgrestisAmeliorates High Fat Diet Induced Dyslipidemia in Syrian Golden Hamsters and Inhibits Adipogenesis in 3T3-L1 Adipocytes
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  21. Clinoptilolite for Treatment of Dyslipidemia: Preliminary Efficacy Study
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  22. Current Drugs and Nutraceuticals for the Treatment of Patients with Dyslipidemias
    Michele Scognamiglio, Dario Costa, Antonio Sorriento, Claudio Napoli A · 2019 · Current Pharmaceutical Design
  23. Integration of Gut Microbiota and Metabolomics for Chinese Medicine Research: Opportunities and Challenges
    Wuwen Feng, Juan Liu, Hao Cheng, Cheng Yun Peng · 2021 · Chinese Journal of Integrative Medicine
  24. DNA‐Binding Affinities and Sequence Specificities of Protoberberine Alkaloids and Their Demethylated Derivatives: A Comparative Study
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  25. Marine natural product des-O-methyllasiodiplodin effectively lowers the blood glucose level in db/db mice via ameliorating inflammation
    Rong Zhou, Zhonghui Lin, Cheng‐Shi Jiang, Jing‐Xu Gong, Lili Chen, Yue‐Wei Guo, Xu Shen · 2013 · Acta Pharmacologica Sinica
  26. Advances in the role of natural products in human gene expression
    Gang CHEN, Di ZHOU, Cheng-Min WANG, Ning LI · 2022 · Chinese Journal of Natural Medicines
  27. Dietary astaxanthin-rich extract ameliorates atherosclerosis/retinopathy and restructures gut microbiome in apolipoprotein E-deficient mice fed on a high-fat diet
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    Marcin Kosmalski, Rafał Frankowski, Kacper Deska, Monika Różycka-Kosmalska, Tadeusz Pietras · 2023 · Nutrients
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  31. Differential interaction behaviors of an alkaloid drug with DMPG liposome membrane as a function of the phase state of the lipid: Nonionic surfactant-induced solubilization of the lipid
    Swagata Sen, Bijan Kumar Paul, Nikhil Guchhait · 2018 · Journal of Molecular Liquids
  32. Synthesis, hypolipidemic and antifungal activity of tetrahydroberberrubine sulfonates
    I. V. Nechepurenko, E. D. Shirokova, Mikhail V. Khvostov, Tatiana S. Frolova, Olga Ivanovna Sinitsyna, Alexander M. Maksimov, Roman A. Bredikhin, Н. И. Комарова, Dmitriy S. Fadeev, Olga A. Luzina et al. · 2019 · Russian Chemical Bulletin
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  37. Improving Secondary Metabolite Production in Tissue Cultures
    Ashwani Kumar · 2015 · Springer eBooks
  38. Pharmacological/Biological Effects of Berberine
    Eva M. Gálvez, M. Perez, P. Domingo, David Núñez-Jurado, Vicente Luis Cebolla, Muriel Matt, Julián Pardo · 2013 · Springer eBooks
  39. Deferoxamine stimulates LDLR expression and LDL uptake in HepG2 cells
    Johann Guillemot, Marie‐Claude Asselin, Delia Susan‐Resiga, Rachid Essalmani, Nabil Georges Seidah · 2015 · Molecular Nutrition & Food Research
  40. Hypolipidemic Berberine Derivatives with a Reduced Aromatic Ring C
    I. V. Nechepurenko, Ul'yana A. Boyarskikh, Mikhail V. Khvostov, Dmitry S. Baev, Н. И. Комарова, М. Л. Филипенко, Tatiana G. Tolstikova, Nariman Faridovich Salakhutdinov · 2015 · Chemistry of Natural Compounds
  41. Inhibitory effects and mechanism of dihydroberberine on hERG channels expressed in HEK293 cells
    Dahai Yu, Lin Li Lv, Fang Li, Bo Zhang, Junnan Wang, Ge Zhan, Lei Zhao, Xin Yu Zhao, Baoxin Li · 2017 · PLoS ONE
  42. Self-assembled filomicelles prepared from polylactide-poly(ethylene glycol) diblock copolymers for sustained delivery of cycloprotoberberine derivatives
    Xue Liu, Yanxiang Wang, Yun Yan Peng, Xin Shen, Feng Su, Yangsheng Chen, Suming Li, Danqing Song · 2018 · Saudi Pharmaceutical Journal
  43. A Concise Synthesis of 8-Oxoberberine and Oxychelerythrine, Natural Isoquinoline Alkaloids through Biomimetic Synthetic Way
    Thanh Nguyen Le · 2006 · Bulletin of the Korean Chemical Society
  44. Beta-Blockers and Berberine: A Possible Dual Approach to Contrast Neuroblastoma Growth and Progression
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  45. Alternative Perspectives: How Chinese Medicine Understands Hypercholesterolemia
    Kylie O’Brien · 2010 · Cholesterol
  46. New advances in novel pharmacotherapeutic candidates for the treatment of metabolic dysfunction-associated steatohepatitis (MASH) between 2022 and 2024
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    Yong-Jie Tan, Tian-Hui Zou, Ke Yu, Jianqiu Sheng, Jin Peng, Mingjie Zhang, Xiaoping Zou, Xiaotan Dou, Side Liu, Shao-Hui Huang et al. · 2025 · Cell Reports Medicine
  48. In silico studies and evaluation of in vitro antidiabetic activity of berberine from ethanol seed extract of Coscinium fenestratum (Gaertn.) Colebr
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  53. Predictive QSAR modeling study on berberine derivatives with hypolipidemic activity
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  58. Review: Current status of therapy in nonalcoholic fatty liver disease
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  59. Metabolic profile associated with glucose and cholesterol lowering effects of berberine in Sprague–Dawley rats
    Zhangjian Jiang, Feng Liu, Eng Shi Ong, Sam Fong Yau Li · 2012 · Metabolomics
  60. Antitumor effects of the combination of cholesterol reducing drugs
    Tadeusz Issat · 2011 · Oncology Reports
  61. Pharmacological regulation of low density lipoprotein receptor expression: Current status and future developments
    Marc Issandou · 2006 · Pharmacology & Therapeutics
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  80. Optimization for ultrahigh pressure extraction of berberine from Cortex Phellodendri by central composite design-response surface methodology
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