Berberine is a novel cholesterol-lowering drug working through a unique mechanism distinct from statins

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Items 301–400 of 1,002

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3. PI3K p55γ promoter activity enhancement is involved in the anti-apoptotic effect of berberine against cerebral ischemia–reperfusion
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4. Considerable fluorescence enhancement upon supramolecular complex formation between berberine and p-sulfonated calixarenes
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5. MYC is a positive regulator of choline metabolism and impedes mitophagy-dependent necroptosis in diffuse large B-cell lymphoma
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6. Liver-target nanotechnology facilitates berberine to ameliorate cardio-metabolic diseases
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7. The Natural Product Berberine is a Human Prolyl Oligopeptidase Inhibitor
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8. Esculeogenin A, a New Tomato Sapogenol, Ameliorates Hyperlipidemia and Atherosclerosis in ApoE-Deficient Mice by Inhibiting ACAT
   Yukio Fujiwara, Naoko Kiyota, Masaharu Hori, Sayaka Matsushita, Yoko Iijima, Koh Aoki, Daisuke Shibata, Motohiro Takeya, Tsuyoshi Ikeda, Toshihiro Nohara et al. · 2007 · Arteriosclerosis Thrombosis and Vascular Biology
9. Modulation of Gut Microbiota by Berberine Improves Steatohepatitis in High-Fat Diet-Fed BALB/C Mice.
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10. Sweet Berberine
    Chenguang Wang, Sathyanarayana Reddy Perumalla, Ruolin Lu, Jianguo Fang, Changquan Calvin Sun · 2015 · Crystal Growth & Design
11. Full-length amyloid precursor protein regulates lipoprotein metabolism and amyloid-β clearance in human astrocytes
    Lauren K. Fong, Max M. Yang, Rodrigo dos Santos Chaves, Sol M. Reyna, Vanessa F. Langness, Grace Woodruff, Elizabeth A. Roberts, Jessica E. Young, Lawrence S.B. Goldstein · 2018 · Journal of Biological Chemistry
12. Berberine suppresses MEK/ERK-dependent Egr-1 signaling pathway and inhibits vascular smooth muscle cell regrowth after in vitro mechanical injury
    Kae‐Woei Liang, Chih-Tai Ting, Sui‐Chu Yin, Ying‐Tsung Chen, Shing‐Jong Lin, James K. Liao, Shih‐Lan Hsu · 2006 · Biochemical Pharmacology
13. Berberine promotes the development of atherosclerosis and foam cell formation by inducing scavenger receptor A expression in macrophage
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14. Hepatoprotective effects of berberine on acetaminophen-induced hepatotoxicity in mice
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15. Alisol A attenuates high‐fat‐diet‐induced obesity and metabolic disorders via the AMPK/ACC/SREBP‐1c pathway
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16. Antifibrotic cardioprotection of berberine via downregulating myocardial IGF-1 receptor-regulated MMP-2/MMP-9 expression in diabetic rats
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17. Apoptosis Induction, a Sharp Edge of Berberine to Exert Anti-Cancer Effects, Focus on Breast, Lung, and Liver Cancer
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18. Berberine – a novel approach to cholesterol lowering
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19. Berberine Improves Insulin Sensitivity by Inhibiting Fat Store and Adjusting Adipokines Profile in Human Preadipocytes and Metabolic Syndrome Patients
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20. Anti‐atherogenic effect of berberine on LXRα‐ABCA1‐dependent cholesterol efflux in macrophages
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21. Role of PCSK9 in lipid metabolism and atherosclerosis
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22. Nutraceuticals as anti-angiogenic agents: hopes and reality.
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23. Effects of Auricularia auricula and its polysaccharide on diet-induced hyperlipidemia rats by modulating gut microbiota
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24. 8,8-Dimethyldihydroberberine with improved bioavailability and oral efficacy on obese and diabetic mouse models
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25. Berberine protects against memory impairment and anxiogenic-like behavior in rats submitted to sporadic Alzheimer’s-like dementia: Involvement of acetylcholinesterase and cell death
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26. Berberine reverses multidrug resistance in Candida albicans by hijacking the drug efflux pump Mdr1p
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27. Medicinal plants and bioactive natural compounds as inhibitors of HMG‐CoA reductase: A literature review
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28. Effect and mechanism of berberine against polycystic ovary syndrome
    Siwei Zhang, Jing Zhou, Hans-Jürgen Gober, Wing Ting Leung, Ling Wang · 2021 · Biomedicine & Pharmacotherapy
29. Berberine Improves Behavioral and Cognitive Deficits in a Mouse Model of Alzheimer’s Disease via Regulation of β-Amyloid Production and Endoplasmic Reticulum Stress
    Yubin Liang, Chenghui Ye, Yuling Chen, Ying Chen, Shiyuan Diao, Min Huang · 2021 · ACS Chemical Neuroscience
30. The berberine-enriched gut commensal Blautia producta ameliorates high-fat diet (HFD)-induced hyperlipidemia and stimulates liver LDLR expression
    Yanan Yang, Qingchun Wang, Wenyi Xu, Jiaqi Yu, Huricha Zhang, Chongming Wu · 2022 · Biomedicine & Pharmacotherapy
31. The mechanism of berberine alleviating metabolic disorder based on gut microbiome
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32. Research progress on the pharmacological effects of berberine targeting mitochondria
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33. Berberine: Pharmacological Features in Health, Disease and Aging
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34. Nutraceutical approaches to non-alcoholic fatty liver disease (NAFLD): A position paper from the International Lipid Expert Panel (ILEP)
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35. Cholesterol-lowering Action of BNA-based Antisense Oligonucleotides Targeting PCSK9 in Atherogenic Diet-induced Hypercholesterolemic Mice
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36. Tomatidine, a Tomato Sapogenol, Ameliorates Hyperlipidemia and Atherosclerosis in ApoE-Deficient Mice by Inhibiting Acyl-CoA:cholesterol Acyl-transferase (ACAT)
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37. Targeted metabolite and transcript profiling for elucidating enzyme function: isolation of novel N‐ methyltransferases from three benzylisoquinoline alkaloid‐producing species
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38. Berberine suppresses gero-conversion from cell cycle arrest to senescence
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39. Berberine ameliorates fatty acid-induced oxidative stress in human hepatoma cells
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40. Update on the Benefits and Mechanisms of Action of the Bioactive Vegetal Alkaloid Berberine on Lipid Metabolism and Homeostasis
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41. Chinese herbal medicine in the treatment of nonalcoholic fatty liver disease
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42. Cholesterol-Dependent Anaplasma phagocytophilum Exploits the Low-Density Lipoprotein Uptake Pathway
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43. Berberine suppresses intestinal disaccharidases with beneficial metabolic effects in diabetic states, evidences from in vivo and in vitro study
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44. Berberine metabolites exhibit triglyceride-lowering effects via activation of AMP-activated protein kinase in Hep G2 cells
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45. Rhizoma coptidis Inhibits LPS-Induced MCP-1/CCL2 Production in Murine Macrophages via an AP-1 and NF κ B-Dependent Pathway
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46. Effect of berberine on cell cycle arrest and cell survival during cerebral ischemia and reperfusion and correlations with p53/cyclin D1 and PI3K/Akt
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47. Berberine Improves Diabetic Encephalopathy Through the SIRT1/ER Stress Pathway in db/db Mice
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49. Lipid lowering agents of natural origin: An account of some promising chemotypes
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50. Berberine alleviates type 2 diabetic symptoms by altering gut microbiota and reducing aromatic amino acids
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51. Berberine for bone regeneration: Therapeutic potential and molecular mechanisms
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52. Berberine improves mesenteric artery insulin sensitivity through up‐regulating insulin receptor‐mediated signalling in diabetic rats
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53. Chinese Medicine in the Battle Against Obesity and Metabolic Diseases
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54. ROS-Responsive Nanoparticle as a Berberine Carrier for OHC-Targeted Therapy of Noise-Induced Hearing Loss
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55. Tolerability and safety of commonly used dietary supplements and nutraceuticals with lipid-lowering effects
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56. Berberine reduces both MMP-9 and EMMPRIN expression through prevention of p38 pathway activation in PMA-induced macrophages
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57. Advance of studies on anti-atherosclerosis mechanism of berberine
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58. Hypolipidemic Effects of Alkaloids from Rhizoma Coptidis in Diet-Induced Hyperlipidemic Hamsters
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59. Activation of AMPK by berberine induces hepatic lipid accumulation by upregulation of fatty acid translocase CD36 in mice
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60. Berberine inhibits colitis-associated tumorigenesis via suppressing inflammatory responses and the consequent EGFR signaling-involved tumor cell growth
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61. Berberine Inhibits the Production of Lysophosphatidylcholine-induced Reactive Oxygen Species and the ERK1/2 Pathway in Vascular Smooth Muscle Cells
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62. The barberry juice effects on metabolic factors and oxidative stress in patients with type 2 diabetes: A randomized clinical trial
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63. Impact of nutraceuticals on markers of systemic inflammation: Potential relevance to cardiovascular diseases – A position paper from the International Lipid Expert Panel (ILEP)
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64. Synthesis and structure–activity relationships of berberine analogues as a novel class of low-density-lipoprotein receptor up-regulators
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65. Berberis aristata / Silybum marianum fixed combination on lipid profile and insulin secretion in dyslipidemic patients
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66. Berberine increases adipose triglyceride lipase in 3T3-L1 adipocytes through the AMPK pathway
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67. Berberine induces apoptosis in non-small-cell lung cancer cells by upregulating miR-19a targeting tissue factor
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68. Medicinal Plants as a Potential and Successful Treatment Option in the Context of Atherosclerosis
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69. Dietary berberine regulates lipid metabolism in muscle and liver of black sea bream ( Acanthopagrus schlegelii ) fed normal or high-lipid diets
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70. Antitumor effect of berberine against primary effusion lymphoma via inhibition of NF ‐κ B pathway
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71. Novel indole and triazole based hybrid molecules exhibit potent anti-adipogenic and antidyslipidemic activity by activating Wnt3a/β-catenin pathway
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72. Non-antibody Approaches to Proprotein Convertase Subtilisin Kexin 9 Inhibition: siRNA, Antisense Oligonucleotides, Adnectins, Vaccination, and New Attempts at Small-Molecule Inhibitors Based on New Discoveries
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73. Studies on Quantitative Determination of Total Alkaloids and Berberine in Five Origins of Crude Medicine “Sankezhen”
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74. Berberine Reduces Fibronectin Expression by Suppressing the S1P-S1P2 Receptor Pathway in Experimental Diabetic Nephropathy Models
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75. The Effects of Berberis vulgaris Fruit Extract on Serum Lipoproteins, apoB, apoA-I, Homocysteine, Glycemic Control and Total Antioxidant Capacity in Type 2 Diabetic Patients.
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76. The Potential Mechanisms of Berberine in the Treatment of Nonalcoholic Fatty Liver Disease
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77. Cellular models for the evaluation of the antiobesity effect of selected phytochemicals from food and herbs
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78. A Novel Promising Frontier for Human Health: The Beneficial Effects of Nutraceuticals in Cardiovascular Diseases
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79. Facilitating effects of berberine on rat pancreatic islets through modulating hepatic nuclear factor 4 alpha expression and glucokinase activity
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80. Berberine regulates peroxisome proliferator-activated receptors and positive transcription elongation factor b expression in diabetic adipocytes
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81. Berberine Protects Mesenchymal Stem Cells against Hypoxia-Induced Apoptosis in Vitro
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82. Synthesis and structure–activity relationship of berberine analogues in LDLR up-regulation and AMPK activation
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83. Berberine increases the expression of NHE3 and AQP4 in sennosideA-induced diarrhoea model
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84. Rohitukine inhibits in vitro adipogenesis arresting mitotic clonal expansion and improves dyslipidemia in vivo
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85. Proprotein convertase subtilisin/kexin type 9 (PCSK9) in Alzheimer’s disease: a genetic and proteomic multi-cohort study
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86. Berberine Improves Cognitive Impairment by Simultaneously Impacting Cerebral Blood Flow and β-Amyloid Accumulation in an APP/tau/PS1 Mouse Model of Alzheimer’s Disease
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87. Berberine inhibited carotid atherosclerosis through PI3K/AKTmTOR signaling pathway
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88. Effect ofRhizoma coptidis(Huang Lian) on Treating Diabetes Mellitus
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89. Berberine Inhibits Hepatic Stellate Cell Proliferation and Prevents Experimental Liver Fibrosis
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90. Berberine Alleviates Olanzapine-Induced Adipogenesis via the AMPKα–SREBP Pathway in 3T3-L1 Cells
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91. Effects of a New Nutraceutical Formulation (Berberine, Red Yeast Rice and Chitosan) on Non-HDL Cholesterol Levels in Individuals with Dyslipidemia: Results from a Randomized, Double Blind, Placebo-Controlled Study
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92. Berberine alleviates adipose tissue fibrosis by inducing AMP-Activated kinase signaling in high-fat diet-induced obese mice
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93. The medicinal plant goldenseal is a natural LDL-lowering agent with multiple bioactive components and new action mechanisms
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94. Comprehensive Evaluation of SCFA Production in the Intestinal Bacteria Regulated by Berberine Using Gas-Chromatography Combined with Polymerase Chain Reaction
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95. Network pharmacology provides new insights into the mechanism of traditional Chinese medicine and natural products used to treat pulmonary hypertension
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96. Hypocholesterolemia of Rhizoma Coptidis alkaloids is related to the bile acid by up-regulated CYP7A1 in hyperlipidemic rats
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97. Enhanced circulating PCSK9 concentration by berberine through SREBP-2 pathway in high fat diet-fed rats
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98. Prolyl Oligopeptidase and Its Role in the Organism: Attention to the Most Promising and Clinically Relevant Inhibitors
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99. Effects of Berberine on Atherosclerosis
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100. Berberrubine, a Main Metabolite of Berberine, Alleviates Non-Alcoholic Fatty Liver Disease via Modulating Glucose and Lipid Metabolism and Restoring Gut Microbiota
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