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RNA interference targeting Fas protects mice from fulminant hepatitis
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Citations
Cites
Lethal effect of the anti-Fas antibody in mice
Ogasawara, J., Watanabe-Fukunaga, R., Adachi, M., Matsuzawa, A., Kasugai, T., Kitamura, Y., Itoh, N., Suda, T., & Nagata, S. (1993) · Nature · doi:10.1038/364806a0 · Cited by 1,881
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Whitehead, K. A., Langer, R., & Anderson, D. G. (2009) · Nature Reviews Drug Discovery · doi:10.1038/nrd2742 · Cited by 3,115
The current state and future directions of RNAi-based therapeutics
Setten, R. L., Rossi, J. J., & Han, S.-P. (2019) · Nature Reviews Drug Discovery · doi:10.1038/s41573-019-0017-4 · Cited by 1,443
RNA therapeutics: beyond RNA interference and antisense oligonucleotides
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Mechanisms and optimization of in vivo delivery of lipophilic siRNAs
Wolfrum, C., Shi, S., Jayaprakash, K. N., Jayaraman, M., Wang, G., Pandey, R. K., Rajeev, K. G., Nakayama, T., Charrise, K., Ndungo, E. M., et al. (2007) · Nature Biotechnology · doi:10.1038/nbt1339 · Cited by 974
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Progress towards in Vivo Use of siRNAs
Behlke, M. A. (2006) · Molecular Therapy · doi:10.1016/j.ymthe.2006.01.001 · Cited by 677
Hu-Lieskovan, S., Heidel, J. D., Bartlett, D. W., Davis, M. E., & Triche, T. J. (2005) · Cancer Research · doi:10.1158/0008-5472.can-05-0565 · Cited by 567
Allerson, C. R., Sioufi, N., Jarres, R., Prakash, T. P., Naik, N., Berdeja, A., Wanders, L., Griffey, R. H., Swayze, E. E., & Bhat, B. (2005) · Journal of Medicinal Chemistry · doi:10.1021/jm049167j · Cited by 448
Caspase 8 small interfering RNA prevents acute liver failure in mice
Zender, L., Hütker, S., Liedtke, C., Tillmann, H. L., Zender, S., Mundt, B., Waltemathe, M., Gösling, T., Flemming, P., Malek, N. P., et al. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1330920100 · Cited by 384
siRNA-based approaches in cancer therapy
Devi, G. R. (2006) · Cancer Gene Therapy · doi:10.1038/sj.cgt.7700931 · Cited by 353
Hydroporation as the mechanism of hydrodynamic delivery
Zhang, G., Gao, X., Song, Y. K., Vollmer, R., Stolz, D. B., Gasiorowski, J. Z., Dean, D. A., & Liu, D. (2004) · Gene Therapy · doi:10.1038/sj.gt.3302210 · Cited by 331
Hepatic fibrosis: molecular mechanisms and drug targets
Lotersztajn, S., Julien, B., Teixeira-Clerc, F., Grenard, P., & Mallat, A. (2005) · Annual Review of Pharmacology and Toxicology · doi:10.1146/annurev.pharmtox.45.120403.095906 · Cited by 325
Development of Lipidoid–siRNA Formulations for Systemic Delivery to the Liver
Akinc, A., Goldberg, M., Qin, J., Dorkin, J. R., Gamba-Vitalo, C., Maier, M., Jayaprakash, K. N., Jayaraman, M., Rajeev, K. G., Manoharan, M., et al. (2009) · Molecular Therapy · doi:10.1038/mt.2009.36 · Cited by 323
Diet associated hepatic steatosis sensitizes to Fas mediated liver injury in mice
Feldstein, A. E., Canbay, A., Guicciardi, M. E., Higuchi, H., Bronk, S. F., & Gores, G. J. (2003) · Journal of Hepatology · doi:10.1016/s0168-8278(03)00460-4 · Cited by 320
Small interfering RNA targeting Fas protects mice against renal ischemia-reperfusion injury
Hamar, P., Song, E., Kökény, G., Chen, A., Ouyang, N., & Lieberman, J. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0406421101 · Cited by 250
Self-citationNonviral methods for siRNA delivery
Gao, K., & Huang, L. (2009) · Molecular Pharmaceutics · doi:10.1021/mp800134q · Cited by 244
Zhu, L., Perche, F., Wang, T., & Torchilin, V. P. (2014) · Biomaterials · doi:10.1016/j.biomaterials.2014.01.060 · Cited by 220
Small interfering RNA: Discovery, pharmacology and clinical development—An introductory review
Ranasinghe, P., Addison, M. L., Dear, J. W., & Webb, D. J. (2023) · British Journal of Pharmacology · doi:10.1111/bph.15972 · Cited by 138
Hepatic Hepcidin Protects against Polymicrobial Sepsis in Mice by Regulating Host Iron Status
Zeng, C., Chen, Q., Zhang, K., Chen, Q., Song, S., & Fang, X. (2015) · Anesthesiology · doi:10.1097/aln.0000000000000466 · Cited by 37
The potential of RNA interference-based therapies for viral infections
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Metadata
- Authors
- Song, E., Lee, S.-K., Wang, J., Ince, N., Ouyang, N., Min, J., Chen, J., Shankar, P., & Lieberman, J.
- Venue
- Nature Medicine
- Published
- 2003-02-10
- Volume
- 9
- Issue
- 3
- Pages
- 347-351
- ISSN
- 1078-8956 (ISSN-L)
- 1546-170X
- OpenAlex
- W1974303227
- Cited by
- 1,110
- References
- 2
- FWCI
- 44.39
- Type
- journal article
- Language
- en
- Open access
- closed
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
