The DOI matches its Crossref record.
Intravital imaging of metastatic behavior through a mammary imaging window
Open accessAbstract
We report a technique to evaluate the same tumor microenvironment over multiple intravital imaging sessions in living mice. We optically marked individual tumor cells expressing photoswitchable proteins in an orthotopic mammary carcinoma and followed them for extended periods through a mammary imaging window. We found that two distinct microenvironments in the same orthotopic mammary tumor affected differently the invasion and intravasation of tumor cells.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cited by
Cancer Invasion and the Microenvironment: Plasticity and Reciprocity
Friedl, P., & Alexander, S. (2011) · Cell · doi:10.1016/j.cell.2011.11.016 · Cited by 1,940
A route to brightly fluorescent carbon nanotubes for near-infrared imaging in mice
Welsher, K., Liu, Z., Sherlock, S. P., Robinson, J. T., Chen, Z., Daranciang, D., & Dai, H. (2009) · Nature Nanotechnology · doi:10.1038/nnano.2009.294 · Cited by 1,287
Real-time imaging reveals the single steps of brain metastasis formation.
Kienast, Y., von Baumgarten, L., Fuhrmann, M., Klinkert, W. E. F., Goldbrunner, R., Herms, J., & Winkler, F. (2010) · Nature Medicine · doi:10.1038/nm.2072 · Cited by 1,138
Classifying collective cancer cell invasion
Friedl, P., Locker, J., Sahai, E., & Segall, J. E. (2012) · Nature Cell Biology · doi:10.1038/ncb2548 · Cited by 963
Self-citationThree-dimensional microfluidic model for tumor cell intravasation and endothelial barrier function
Zervantonakis, I. K., Hughes-Alford, S. K., Charest, J. L., Condeelis, J. S., Gertler, F. B., & Kamm, R. D. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1210182109 · Cited by 872
Self-citationTGF-β signaling and epithelial–mesenchymal transition in cancer progression
Katsuno, Y., Lamouille, S., & Derynck, R. (2013) · Current Opinion in Oncology · doi:10.1097/cco.0b013e32835b6371 · Cited by 786
Sabeh, F., Shimizu-Hirota, R., & Weiss, S. J. (2009) · Journal of Cell Biology · doi:10.1083/jcb.200807195 · Cited by 658
Collagen-based cell migration models in vitro and in vivo
Wolf, K., Alexander, S., Schacht, V., Coussens, L. M., von Andrian, U. H., van Rheenen, J., Deryugina, E., & Friedl, P. (2009) · Seminars in Cell & Developmental Biology · doi:10.1016/j.semcdb.2009.08.005 · Cited by 637
Self-citationPereira, E. R., Kedrin, D., Seano, G., Gautier, O., Meijer, E. F. J., Jones, D., Chin, S.-M., Kitahara, S., Bouta, E. M., Chang, J., et al. (2018) · Science · doi:10.1126/science.aal3622 · Cited by 477
Self-citationPittet, M. J., & Weissleder, R. (2011) · Cell · doi:10.1016/j.cell.2011.11.004 · Cited by 466
Directed cell invasion and migration during metastasis
Bravo-Cordero, J. J., Hodgson, L., & Condeelis, J. (2012) · Current Opinion in Cell Biology · doi:10.1016/j.ceb.2011.12.004 · Cited by 462
Self-citationInvadopodia Are Required for Cancer Cell Extravasation and Are a Therapeutic Target for Metastasis
Leong, H. S., Robertson, A. E., Stoletov, K., Leith, S. J., Chin, C. A., Chien, A. E., Hague, M. N., Ablack, A., Carmine-Simmen, K., McPherson, V. A., et al. (2014) · Cell Reports · doi:10.1016/j.celrep.2014.07.050 · Cited by 400
Unravelling the complexity of metastasis — molecular understanding and targeted therapies
Sethi, N., & Kang, Y. (2011) · Nature Reviews Cancer · doi:10.1038/nrc3125 · Cited by 397
Surgical implantation of an abdominal imaging window for intravital microscopy
Ritsma, L., Steller, E. J. A., Ellenbroek, S. I. J., Kranenburg, O., Borel Rinkes, I. H. M., & van Rheenen, J. (2013) · Nature Protocols · doi:10.1038/nprot.2013.026 · Cited by 279
Self-citationFumagalli, A., Drost, J., Suijkerbuijk, S. J. E., van Boxtel, R., de Ligt, J., Offerhaus, G. J., Begthel, H., Beerling, E., Tan, E. H., Sansom, O. J., et al. (2017) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1701219114 · Cited by 258
Self-citationFerrari, N., Ranftl, R., Chicherova, I., Slaven, N. D., Moeendarbary, E., Farrugia, A. J., Lam, M., Semiannikova, M., Westergaard, M. C. W., Tchou, J., et al. (2019) · Nature Communications · doi:10.1038/s41467-018-07987-0 · Cited by 164
Nuclear F-Actin Counteracts Nuclear Deformation and Promotes Fork Repair during Replication Stress
Lamm, N., Read, M. N., Nobis, M., Van Ly, D., Page, S. G., Masamsetti, V. P., Timpson, P., Biro, M., & Cesare, A. J. (2020) · Nature Cell Biology · doi:10.1038/s41556-020-00605-6 · Cited by 156
Iron in the Tumor Microenvironment-Connecting the Dots
Pfeifhofer-Obermair, C., Tymoszuk, P., Petzer, V., Weiss, G., & Nairz, M. (2018) · Frontiers in Oncology · doi:10.3389/fonc.2018.00549 · Cited by 151
Actin dynamics during tumor cell dissemination
(2021) · International Review of Cell and Molecular Biology · doi:10.1016/bs.ircmb.2020.09.004 · Cited by 39
Intravital microscopy for real-time monitoring of drug delivery and nanobiological processes
Momoh, J., Kapsokalyvas, D., Vogt, M., Hak, S., Kiessling, F., van Zandvoort, M., Lammers, T., & Sofias, A. M. (2022) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2022.114528 · Cited by 33
Liu, T. W., Gammon, S. T., Fuentes, D., & Piwnica-Worms, D. (2021) · Cells · doi:10.3390/cells10030489 · Cited by 16
Metadata
- Authors
- Kedrin, D., Gligorijevic, B., Wyckoff, J., Verkhusha, V. V., Condeelis, J., Segall, J. E., & van Rheenen, J.
- Venue
- Nature Methods
- Published
- 2008-11-09
- Volume
- 5
- Issue
- 12
- Pages
- 1019-1021
- ISSN
- 1548-7091 (ISSN-L)
- 1548-7105
- OpenAlex
- W1999700615
- Cited by
- 391
- References
- 0
- FWCI
- 12.94
- Type
- journal article
- Language
- en
- Open access
- green
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
