Directed evolution of APEX2 for electron microscopy and proximity labeling

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Galectin-3 Coordinates a Cellular System for Lysosomal Repair and Removal

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Exosomes surf on filopodia to enter cells at endocytic hot spots, traffic within endosomes, and are targeted to the ER

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Proteomics of Primary Cilia by Proximity Labeling

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Properties of Stress Granule and P-Body Proteomes

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Mitochondrial calcium exchange in physiology and disease

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Genetic dissection of Flaviviridae host factors through genome-scale CRISPR screens

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Proteomic Analysis of Unbounded Cellular Compartments: Synaptic Clefts

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A proximity labeling strategy provides insights into the composition and dynamics of lipid droplet proteomes

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Chemistry for Covalent Modification of Endogenous/Native Proteins: From Test Tubes to Complex Biological Systems

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RNA–protein interaction detection in living cells

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Discovery and characterization of smORF-encoded bioactive polypeptides

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Mechanism of adrenergic CaV1.2 stimulation revealed by proximity proteomics

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Determination of host proteins composing the microenvironment of coronavirus replicase complexes by proximity-labeling

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Subcellular connectomic analyses of energy networks in striated muscle

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μMap-Red: Proximity Labeling by Red Light Photocatalysis

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Activity-dependent trafficking of lysosomes in dendrites and dendritic spines

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Dense neuronal reconstruction through X-ray holographic nano-tomography

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Dynamic mapping of proteome trafficking within and between living cells by TransitID

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The ciliary membrane‐associated proteome reveals actin‐binding proteins as key components of cilia

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The Dawn of a New Era: Targeting the “Undruggables” with Antibody-Based Therapeutics

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Engineered allostery in light-regulated LOV-Turbo enables precise spatiotemporal control of proximity labeling in living cells

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Labeling and Single-Molecule Methods To Monitor G Protein-Coupled Receptor Dynamics

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The Mammalian Crumbs Complex Defines a Distinct Polarity Domain Apical of Epithelial Tight Junctions

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The Mitochondrial Ca2+ Uptake and the Fine-Tuning of Aerobic Metabolism

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Architecture Mapping of the Inner Mitochondrial Membrane Proteome by Chemical Tools in Live Cells

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Spatiotemporal-resolved protein networks profiling with photoactivation dependent proximity labeling

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Mitochondrial membrane proteins and VPS35 orchestrate selective removal of mtDNA

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Proteomics Approaches for Biomarker and Drug Target Discovery in ALS and FTD

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Spatiotemporally-resolved mapping of RNA binding proteins via functional proximity labeling reveals a mitochondrial mRNA anchor promoting stress recovery

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Genetically encoded photocatalytic protein labeling enables spatially-resolved profiling of intracellular proteome

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EGFR is required for Wnt9a/Fzd9b signalling specificity in haematopoietic stem cells

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Enhanced mTORC1 signaling and protein synthesis in pathologic α-synuclein cellular and animal models of Parkinson’s disease

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Tyrosinase-Based Proximity Labeling in Living Cells and In Vivo

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Mitochondrial matrix RTN4IP1/OPA10 is an oxidoreductase for coenzyme Q synthesis

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Cellular-scale proximity labeling for recording cell spatial organization in mouse tissues

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Photocatalytic Proximity Labeling for Profiling the Subcellular Organization of Biomolecules

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Highly effective proximate labeling in Drosophila

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A fluorogenic complementation tool kit for interrogating lipid droplet–organelle interaction

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Compartment-Specific Labeling of Bacterial Periplasmic Proteins by Peroxidase-Mediated Biotinylation

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The anti-viral dynamin family member MxB participates in mitochondrial integrity

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Strategies to Investigate Ubiquitination in Huntington's Disease

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Enzymatic Recording of Local Hydrogen Peroxide Generation Using Genetically Encodable Enzyme

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Proximity-Dependent Labeling of Cysteines

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Differentiation granules, a dynamic regulator of T. brucei development

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Enhanced mTORC1 signaling and Protein Synthesis in Parkinson’s Disease Pathogenesis Disease Pathogenesis

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Fibroblast growth factor receptor substrate 2 interactome mapping reveals novel candidate interactors associated with migration and invasion

(2026) · doi:10.1186/s12964-026-02943-8