Cited by 568Migraine and Headache StudiesPain Mechanisms and TreatmentsCircadian rhythm and melatonin

The DOI matches its Crossref record; 46 of the 46 references it cites were found in a registry or an index.

A neural mechanism for exacerbation of headache by light

Open access

Noseda, Rodrigo, Kainz, Vanessa, Jakubowski, Moshe, Gooley, Joshua J, Saper, Clifford B, Digre, Kathleen, Burstein, Rami·2010·Nature Neuroscience

DOI 10.1038/nn.2475PMC PMC2818758

Open this paper in CoChat — free account

Abstract

The perception of migraine headache, which is mediated by nociceptive signals transmitted from the cranial dura mater to the brain, is uniquely exacerbated by exposure to light. We found that exacerbation of migraine headache by light is prevalent among blind individuals who maintain non-image-forming photoregulation in the face of massive rod/cone degeneration. Using single-unit recording and neural tract tracing in the rat, we identified dura-sensitive neurons in the posterior thalamus whose activity was distinctly modulated by light and whose axons projected extensively across layers I-V of somatosensory, visual and associative cortices. The cell bodies and dendrites of such dura/light-sensitive neurons were apposed by axons originating from retinal ganglion cells (RGCs), predominantly from intrinsically photosensitive RGCs, the principle conduit of non-image-forming photoregulation. We propose that photoregulation of migraine headache is exerted by a non-image-forming retinal pathway that modulates the activity of dura-sensitive thalamocortical neurons.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Integrity signals

Registry

Crossref · 10.1038/nn.2475

Cites

46 of 46 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

The Rat Brain in Stereotaxic Coordinates
Paxinos, G., & Watson, C. (1983) · Elsevier eBooks · doi:10.1016/c2009-0-63235-9 · Cited by 28,585
The International Classification of Headache Disorders: 2nd edition
Olesen, J., Goadsby, P. J., & Steiner, T. (2003) · The Lancet Neurology · doi:10.1016/s1474-4422(03)00590-8 · Cited by 5,046
Phototransduction by retinal ganglion cells that set the circadian clock
Berson, D. M., Dunn, F. A., & Takao, M. (2002) · Science · doi:10.1126/science.1067262 · Cited by 3,629
Melanopsin-Containing Retinal Ganglion Cells: Architecture, Projections, and Intrinsic Photosensitivity
Hattar, S., Liao, H.-W., Takao, M., Berson, D. M., & Yau, K.-W. (2002) · Science · doi:10.1126/science.1069609 · Cited by 2,734
Posterior parietal association cortex of the monkey: command functions for operations within extrapersonal space
Mountcastle, V. B., Lynch, J. C., Georgopoulos, A., Sakata, H., & Acuna, C. (1975) · Journal of Neurophysiology · doi:10.1152/jn.1975.38.4.871 · Cited by 2,061
Anatomy and physiology of a color system in the primate visual cortex
Livingstone, M. S., & Hubel, D. H. (1984) · Journal of Neuroscience · doi:10.1523/jneurosci.04-01-00309.1984 · Cited by 1,637
Melanopsin-expressing ganglion cells in primate retina signal colour and irradiance and project to the LGN
Dacey, D. M., Liao, H.-W., Peterson, B. B., Robinson, F. R., Smith, V. C., Pokorny, J., Yau, K.-W., & Gamlin, P. D. (2005) · Nature · doi:10.1038/nature03387 · Cited by 1,333
A Novel Human Opsin in the Inner Retina
Provencio, I., Rodriguez, I. R., Jiang, G., Hayes, W. P., Moreira, E. F., & Rollag, M. D. (2000) · The Journal of Neuroscience · doi:10.1523/jneurosci.20-02-00600.2000 · Cited by 1,290
Melanopsin and rod-cone photoreceptive systems account for all major accessory visual functions in mice
Hattar, S., Lucas, R. J., Mrosovsky, N., Thompson, S., Douglas, R. H., Hankins, M. W., Lem, J., Biel, M., Hofmann, F., Foster, R. G., et al. (2003) · Nature · doi:10.1038/nature01761 · Cited by 1,245
Central projections of melanopsin‐expressing retinal ganglion cells in the mouse
Hattar, S., Kumar, M., Park, A., Tong, P., Tung, J., Yau, K., & Berson, D. M. (2006) · Journal of Comparative Neurology · doi:10.1002/cne.20970 · Cited by 996

Flagged first, then by citations

Show all 46 references

Research works printed but not linked: 1

Lowenfeld, I. The Dazzling Syndrome (Wane State University Press, Detroit, Michigan, USA, 1993).

Sorted by citations

Items 401–500 of 568

Relationship between absorptive lenses and contrast sensitivity in healthy young subjects with glare under photopic- and mesopic-vision conditions
Kanazawa, M., & Uozato, H. (2013) · Optical Review · doi:10.1007/s10043-013-0051-0 · Cited by 3
Mapping the Brain in Primary Headache Disorders
Schankin, C. J., & Goadsby, P. J. (2015) · Elsevier eBooks · doi:10.1016/b978-0-12-397025-1.00140-8 · Cited by 3
Enhancement of ERK phosphorylation and photic responses in Vc/C1 neurons of a migraine model
Hitomi, S., Okada‐Ogawa, A., Sato, Y., Shibuta, I., Shinoda, M., Imamura, Y., Ono, K., & Iwata, K. (2017) · Neuroscience Letters · doi:10.1016/j.neulet.2017.03.023 · Cited by 3
Headache, Facial Pain, and Disorders of Facial Sensation
Ko, M. W., & Prasad, S. (2018) · Elsevier eBooks · doi:10.1016/b978-0-323-34044-1.00019-5 · Cited by 3
Effect of blue light from LCD on VDT work: Experiment using blue light reduction function LCD
Yoshimura, K., Sakakibara, H., Ikeda, M., Shibata, K., & Tamamura, Y. (2019) · Journal of the Society for Information Display · doi:10.1002/jsid.863 · Cited by 3
Connection between right-to-left shunt and photosensitivity: a community-based cross-sectional study
Dong, B., Ji, S., Li, Y., Li, H., Yang, R., Yang, N., Liu, Z., Zhu, C., Wang, H., Tang, Y., et al. (2023) · Frontiers in Neurology · doi:10.3389/fneur.2023.1177879 · Cited by 3
Increased pupillary constriction velocity in benign essential blepharospasm associated with photophobia
Byun, Y., Kim, S., Paik, J., & Yang, S.-W. (2019) · PLoS ONE · doi:10.1371/journal.pone.0217924 · Cited by 3
Migraines and Cortical Spreading Depression
Dahlem, M. A. (2015) · Encyclopedia of Computational Neuroscience · doi:10.1007/978-1-4614-6675-8_507 · Cited by 3
Neural signatures of extreme sensitivities to light: cortical markers in hypersensitive and hyposensitive individuals via EEG
Salvati, V., Otani, S., & Tartaglia, E. M. (2025) · Frontiers in Neuroscience · doi:10.3389/fnins.2025.1542154 · Cited by 2
Hippocampal neural circuit mechanisms in Alzheimer's disease revealed by viral-genetic circuit mapping
Ye, Q., Gast, G., Holmes, T. C., & Xu, X. (2025) · Neurobiology of Disease · doi:10.1016/j.nbd.2025.107139 · Cited by 2
3T MRI thalamic segmentation reveals no macrostructural changes in interictal episodic migraine without aura compared to healthy controls
Giardina, I., Renzo, A. D., Chiffi, D., Giuliani, G., Sebastianelli, G., Casillo, F., Abagnale, C., Ziccardi, L., Pucci, A., Parisi, V., et al. (2025) · The Journal of Headache and Pain · doi:10.1186/s10194-025-02196-9 · Cited by 2
Animal Models of Migraine
Andreou, A. P., & Oshinsky, M. L. (2015) · Headache · doi:10.1007/978-3-319-15621-7_2 · Cited by 2
COLOR PERCEPTION THEORIES. PHOTORECEPTORS STRUCTURE OF EYE RETINA
Chuprov, A. D., Sinkova, V. I., & Kuznetsov, I. V. (2021) · Современные проблемы науки и образования · doi:10.17513/spno.31287 · Cited by 2
Bimatoprost Ophthalmic Solution (BOS) 0.3 mg w/v for 1 Open Trial of Long-term Preventive Therapy of Migraine in 3 patients with Pathophysiologic Shift from Brain to Eye
Gupta, V. K. (2023) · Journal of Neuroscience and Neurological Disorders · doi:10.29328/journal.jnnd.1001087 · Cited by 2
Looking for a Beam of Light to Heal Chronic Pain
Xu, J., Zhang, H., Chen, D. D., Xu, K., Li, Z., Wu, H., Geng, X., Wei, X., Wu, J., Cui, W., et al. (2024) · Journal of Pain Research · doi:10.2147/jpr.s455549 · Cited by 3
Is canonical SD a clinically relevant model of migraine? Argument pro
Öncel, M. M., & Harriott, A. M. (2025) · The Journal of Headache and Pain · doi:10.1186/s10194-025-02175-0 · Cited by 2
Sleep deprivation, headache, and Fos immunohistochemistry
Kim, S., & Park, J. (2021) · Elsevier eBooks · doi:10.1016/b978-0-12-820589-1.00019-1 · Cited by 2
The photic driving response in electroencephalogram in migraine patients
Takashima, R., Tanaka, H., Kimoto, K., Watanabe, Y., & Hirata, K. (2012) · ICME International Conference on Complex Medical Engineering (CME) · doi:10.1109/iccme.2012.6275694 · Cited by 2
A Stereotyped Syndrome with Retro-Ocular Pain, Photophobia, and Visual Disturbance Masquerading as Optic Neuritis: Case Series
Jefferis, J. M., Littlewood, R. A., Pepper, I. M., & Hickman, S. J. (2018) · Neuro-Ophthalmology · doi:10.1080/01658107.2018.1437753 · Cited by 2
Neurobiological Basis of Migraine
Holland, P. R., Hoffmann, J., & Goadsby, P. J. (2019) · Oxford University Press eBooks · doi:10.1093/oxfordhb/9780190860509.013.27 · Cited by 2
Current advances in the management of cluster headaches
Mavridis, T., Breza, M., Deligianni, C. I., & Mitsikostas, D. D. (2021) · Expert Opinion on Pharmacotherapy · doi:10.1080/14656566.2021.1924148 · Cited by 2
Once-Weekly Nocturnal Ocular Choroidal Vascular Decongestion by Topical Long-acting Timolol Ophthlamic Solution Applied to Headache-Ipsilateral eye to Prevent Weekend-Migraine Attacks: Smartphone-app
Gupta, V. K. (2021) · Neuroscience and Neurological Surgery · doi:10.31579/2578-8868/179 · Cited by 2
From neuroimaging to the bedside: Take the sheets off the thalamus
Coppola, G. (2013) · Cephalalgia · doi:10.1177/0333102412474508 · Cited by 2
Headache Highlights 2016: Junior Editors’ Choice
Gudmundsson, L. S., Harriott, A. M., & Hoffmann, J. (2017) · Cephalalgia · doi:10.1177/0333102417691763 · Cited by 2
Should I be using pit and fissure sealants or amalgam?
Silverstone, L. M. (1976) · PubMed · Cited by 2
Tbr2-expressing retinal ganglion cells are ipRGCsPreprint
Mao, C., Chen, C.-K., Kiyama, T., Weber, N., Whitaker, C. M., Pan, P., Badea, T. C., & Massey, S. C. (2020) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2020.06.17.153551 · Cited by 2
Migraine Pathogenesis
Dodick, D. W., & Silberstein, S. D. (2016) · doi:10.1093/med/9780199793617.003.0005 · Cited by 2
Photophobia as the Presenting Symptom of Internal Carotid Artery Dissection
Pellegrini, F., Cirone, D., & Stafa, A. (2019) · Neuro-Ophthalmology · doi:10.1080/01658107.2019.1580298 · Cited by 1
Laws of Pathophysiology of Migraine in the Third Millennium
Gupta, V. K. (2024) · Journal of Neuroscience and Neurological Disorders · doi:10.29328/journal.jnnd.1001094 · Cited by 1
Age-based effects of yellow lenses on discomfort glare from white LED headlights
Iizuka, T., Kawamorita, T., & Ishikawa, H. (2024) · Optical Review · doi:10.1007/s10043-024-00926-z · Cited by 1
Effect of Tinted Lenses on Migraine Patients as Assessed by Pupil Response and Heart Rate Variability Analysis
Kamata, Y., Hara, N., Nozaki, T., & Niida, T. (2024) · Neurology and Clinical Neuroscience · doi:10.1111/ncn3.12869 · Cited by 1
Amplifying and ameliorating light avoidance in mice with photoreceptor targeting and calcitonin gene‐related peptide sensitization
Kaiser, E. A., Cavanah, A., Aguirre, G. K., & Jensen, F. E. (2025) · Headache The Journal of Head and Face Pain · doi:10.1111/head.70018 · Cited by 1
Cone-Specific Filter-Based Neuromodulation: A Proposed Clinical Framework for Amblyopia, Strabismus, and ADHD
Ibrahimi, D., & García‐Martínez, J. R. (2025) · Clinics and Practice · doi:10.3390/clinpract16010003 · Cited by 1
Effects of erenumab on migraine aura frequency: a REFORM study
Jakobsen, J. T., Karlsson, W. K., Christensen, R. H., Al‐Khazali, H. M., Ashina, M., & Ashina, H. (2026) · The Journal of Headache and Pain · doi:10.1186/s10194-026-02338-7 · Cited by 1
Antinociceptive Effects of Exogenous and Endogenous Carbon Monoxide in the Nitroglycerin-Induced Migraine Model in Rats
Ananev, A. S., Гилиждинова, К. Р., Nurmieva, D., Yakovleva, O. V., Shaidullova, K., & Ситдикова, Г. Ф. (2026) · International Journal of Molecular Sciences · doi:10.3390/ijms27104346 · Cited by 1
Corneal nerve alterations in migraine: a systematic review of in vivo confocal microscopy and esthesiometry findings
Mejía-Salgado, G., Tello, A., Galvis, V., Arenas, D. C. V., Forero-Vargas, C., de‐la‐Torre, A., & Galor, A. (2026) · Contact Lens and Anterior Eye · doi:10.1016/j.clae.2026.102694 · Cited by 1
Photophobia in Post-Concussive Syndrome
Ahmad, M. T., & Singman, E. L. (2021) · Springer eBooks · doi:10.1007/978-3-030-74103-7_22 · Cited by 1
Other Potential Uses of Coloured Filters in the Clinic
Wilkins, A. J., & Evans, B. J. W. (2022) · Springer eBooks · doi:10.1007/978-3-031-03930-0_11 · Cited by 1
Abnormal visual cortex activity using functional magnetic resonance imaging in treatment resistant photophobia in Friedreich Ataxia
Gunawardene, A. N., Reyes, N. L., Valdés-Arias, D., Ortuğ, A., Martinez, J. D., Galor, A., & Moulton, E. A. (2024) · American Journal of Ophthalmology Case Reports · doi:10.1016/j.ajoc.2024.102213 · Cited by 1
Response to “Optical Lens Tinting—A Review of its Functional Mechanism, Efficacy, and Applications”
Wilkins, A. J. (2020) · touchREVIEWS in Ophthalmology · doi:10.17925/usor.2020.13.1.16 · Cited by 1
Should “Retro-ocular Pain, Photophobia and Visual Acuity Loss” Be Recognised as a Distinct Entity? The ROPPVAL Syndrome
Pellegrini, F., Mandarà, E., & Brocca, D. (2021) · Neuro-Ophthalmology · doi:10.1080/01658107.2021.1887289 · Cited by 1
Pain Following Endoscopic Foreheadplasty Surgery in Women
Lassegard, J. C., Dubin, B. J., Compton, P. A., Charles, A. C., & Macey, P. M. (2021) · Aesthetic Surgery Journal · doi:10.1093/asj/sjab416 · Cited by 1
Meta‐analysis of the effects of anti‐migraine therapeutics in the rat trigeminovascular nociception model as a tool for design optimization
Dolgorukova, A., Protsenko, E., Isaeva, J., Gagloeva, V., Verbitskaya, E., Berkovich, R., & Sokolov, A. (2023) · European Journal of Neuroscience · doi:10.1111/ejn.16030 · Cited by 2
Sensitization and Photophobia in Migraine
Schain, A. J., & Burstein, R. (2017) · Wiley eBooks · doi:10.1002/9781118967225.ch7 · Cited by 1
Self-citation
Influence of Light Exposure on the Melanopsin Driven Pupil Response and Circadian Rhythm
Abbott, K. S. (2018) · Masters Thesis · Cited by 1
Our choice from the recent literature
(2010) · Nature Photonics · doi:10.1038/nphoton.2010.9 · Cited by 1
Brain morphology, functional performance, and clinical features of migraine patients - a cross-sectional study
Maciel, N. M. (2022) · Digital Library of Theses and Dissertations (Universidade de São Paulo) · doi:10.11606/t.17.2022.tde-20062022-153053 · Cited by 1
Migraines and Cortical Spreading Depression
Dahlem, M. A. (2013) · Encyclopedia of Computational Neuroscience · doi:10.1007/978-1-4614-7320-6_507-5 · Cited by 1
Circadian rhythmicity and photobiological mechanisms of light sensitivity and discomfort glare in humansPreprint
Daguet, I., Raverot, V., & Gronfier, C. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.02.05.578180 · Cited by 1
Audiovestibular sensory processing in migraine
Murdin, L. J. (2011) · UCL Discovery (University College London) · Cited by 1
Recent Topics in the Pupillary Light Reflex
Asakawa, K., & Ishikawa, H. (2014) · 神経眼科 · doi:10.11476/shinkeiganka.31.527
Shining a spotlight on headaches
Molnár, Z., & Taylor, J. S. H. (2010) · Nature Neuroscience · doi:10.1038/nn0210-150
Headache: new genes, new mechanisms, and new therapies
Charles, A. C. (2010) · The Lancet Neurology · doi:10.1016/s1474-4422(10)70309-4
Traitements de fond de la maladie migraineuse
Lévy-Chavagnat, D. (2011) · Actualités Pharmaceutiques · doi:10.1016/s0515-3700(11)70852-7
Too Much of a Good Thing? Brain Hyper Excitability and Migraine
Becker, W. J., & Chitsantikul, P. (2011) · Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques · doi:10.1017/s031716710001129x
Headache: new genes, new mechanisms, and new therapies
Bushby, K. (2011)
Migraine
Green, M. W. (2013) · Cambridge University Press eBooks · doi:10.1017/cbo9781139206952.003
Regulation of CGRP gene expression and effects on light aversive behavior
Raddant, A. C., Russo, A. F., Anderson, M. G., Lee, A., Johnson, A. K., & Johnson, W. A. (2013) · doi:10.17077/etd.84iwepmv
Neuro-imagerie fonctionnelle et migraine
Demarquay, G., & Créac’h, C. (2014) · Douleur et Analgésie · doi:10.1007/s11724-014-0374-z
Effects of acupuncture and moxibustion on headache and the present status quo
Hashimoto, Y., Toriumi, H., KIKUCHI, T., SHINOHARA, S., & KASUYA, D. (2014) · Zen Nihon Shinkyu Gakkai zasshi (Journal of the Japan Society of Acupuncture and Moxibustion) · doi:10.3777/jjsam.64.18
Abstracts and Citations
Landy, S. H., Kaniecki, R. G., & Taylor, F. R. (2011) · Headache The Journal of Head and Face Pain · doi:10.1111/j.1526-4610.2011.01876.x
Neuro-Opthalmological Aspects of Headaches from the Neurologist’s Aspect
Ertsey, C. (2016) · Springer eBooks · doi:10.1007/978-3-319-28956-4_65
Odorant‐Triggered Migraine Attacks in a Case of Iatrogenic Olfactory Neuropathy
Justusson, E., Han, D. Y., Kapoor, S., & Smith, J. H. (2016) · Headache The Journal of Head and Face Pain · doi:10.1111/head.12899
Physiology of the Meningeal Sensory Pathway
Strassman, A. M., & Melo‐Carrillo, A. (2017) · doi:10.1002/9781118967225.ch2
Imaging Pain and Headache
Hodkinson, D. J., Wilcox, S. L., & Borsook, D. (2017) · doi:10.1002/9781118967225.ch21
A Novel Animal Model for Investigating the Neural Basis of Focal Dystonia
Evinger, L. (2016)
Neurologie: Jahresrückblick 2010. Teil 1
Bassetti, C. L., Agazzi, P., BornaticoValsangiacomo, F., Carota, A., Calabrese, P., Cereda, C. W., Caporale, C., Galati, S., Gobbi, C., Manconi, M., et al. (2011) · Swiss Medical Forum ‒ Schweizerisches Medizin-Forum · doi:10.4414/smf.2011.07512
A theory of visual stress and its application to the use of coloured filters for reading
Wilkins, A. J. (2018) · John Benjamins Publishing Company eBooks · doi:10.1075/z.217.17wil
Nanoparticle Notch Filters for Selective Filtering of Blue Light in Contact Lenses
Krishnakumar, H. (2018) · UWSpace (University of Waterloo)
Abstracts and Citations
Kaniecki, R. G., Taylor, F. R., & Landy, S. H. (2011) · Headache The Journal of Head and Face Pain · doi:10.1111/j.1526-4610.2011.01897.x
Neurologie: Jahresrückblick 2010. Teil 2
Bassetti, C. L., Agazzi, P., BornaticoValsangiacomo, F., Carota, A., Calabrese, P., Cereda, C. W., Caporale, C., Galati, S., Gobbi, C., Manconi, M., et al. (2011) · Swiss Medical Forum ‒ Schweizerisches Medizin-Forum · doi:10.4414/smf.2011.07517
Desconforto induzido pela luz, controle postural e sintomas vestibulares em mulheres com migrânea - um estudo controlado
Pinheiro, C. F. (2019) · doi:10.11606/t.17.2019.tde-01022019-102741
Illusory motion perception in migraine
He, C. (2019) · Minerva Access (University of Melbourne)
Cutting-edge technology and nocturnal headaches in adolescent smart phone users in Chiang Mai, Thailand
Chongchitpaisan, W., Wiwatanadate, P., Tanprawate, S., Narkpongphun, A., & Siripon, N. (2019) · Journal of Health Research · doi:10.1108/jhr-01-2019-0013
Contribution of animal studies to migraine research
Shibata, M. (2019) · Neurology and Clinical Neuroscience · doi:10.1111/ncn3.12359
REPRINTED WITH PERMISSION OF IASP – PAIN 160 (2019) 1494–1501: Migraine understood as a sensory threshold disease
Peng, K., & Maya, A. (2020) · Ból · doi:10.5604/01.3001.0013.7394
My child seems to hate the bright light
Funnell, C. L. (2013) · Elsevier eBooks · doi:10.1016/b978-0-7020-4691-9.00099-6
Melanopsin photoreceptor contributions to brightness perception and photophobia
Dey, A. (2020) · Queensland University of Technology · doi:10.5204/thesis.eprints.205723
On The Bright Side of Life - The Effect of Ambient Light Intensity on Postsurgical Patient-Reported OutcomesPreprint
Scheller, J., Komann, M., Weinmann, C., Weinmann, J., Scharnagel, S., Mielke, A., Pogatzki-Zahn, E. M., Heifeld, S., & Meißner, W. (2021) · Research Square · doi:10.21203/rs.3.rs-403129/v1
Classification, Mechanism, Biochemistry, and Genetics of Headache
Ahn, A. H. (2015) · Elsevier eBooks · doi:10.1016/b978-0-12-800901-7.00002-1
New directions for structural and functional neuroimaging markers in migraine
Veréb, D. (2021) · doi:10.14232/phd.10784
Headache and Sleep
Diamond, J. A., & Natbony, L. R. (2021) · Springer eBooks · doi:10.1007/978-3-030-71513-7_6
Neurological and medical disorders: circadian rhythm disruption comorbidity
Reynolds, A. M. (2021) · Elsevier eBooks · doi:10.1016/b978-0-12-822963-7.00136-5
片頭痛における内因性光感受性網膜神経節細胞 (ipRGC)の光応答の特性
永田, 栄. (2021) · doi:10.50860/jjho.48.1_170
Current World Literature
(2011) · Current Opinion in Neurology · doi:10.1097/wco.0b013e328347b40e
Abstracts and Citations
Taylor, F. R., Kaniecki, R. G., & Landy, S. H. (2012) · Headache The Journal of Head and Face Pain · doi:10.1111/j.1526-4610.2011.02072.x
Faculty Opinions recommendation of Light Affects Mood and Learning through Distinct Retina-Brain Pathways.
Kawasaki, A. (2019) · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · doi:10.3410/f.733886629.793560080
Response to letter to the Editor
Pierelli, F., Iacovelli, E., Bracaglia, M., Serrao, M., & Coppola, G. (2013) · Pain · doi:10.1016/j.pain.2013.12.013
Abstracts and Citations
Kaniecki, R. G., Taylor, F. R., & Landy, S. H. (2013) · Headache The Journal of Head and Face Pain · doi:10.1111/head.12147
Transient, Unexplained, and Psychogenic Visual Loss in Children
Brodsky, M. C. (2016) · Springer eBooks · doi:10.1007/978-1-4939-3384-6_5
Abstracts and Citations
Kaniecki, R. G., & Taylor, F. R. (2015) · Headache The Journal of Head and Face Pain · doi:10.1111/head.12478
Abstracts and Citations
Kaniecki, R. G., Landy, S. H., & Taylor, F. R. (2012) · Headache The Journal of Head and Face Pain · doi:10.1111/j.1526-4610.2012.02118.x
Faculty Opinions recommendation of A systems neuroscience approach to migraine.
Wang, S. (2018) · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · doi:10.3410/f.732810774.793545896
Abstracts and Citations
Taylor, F. R., Cooper, W. M., & Kaniecki, R. G. (2015) · Headache The Journal of Head and Face Pain · doi:10.1111/head.12575
Cyclops
(2010) · Canadian Journal of Ophthalmology · doi:10.1016/s0008-4182(10)80003-1
Meta-analysis of the effects of clinically-effective therapeutics in the preclinical migraine model as a tool for design optimisationPreprint
Dolgorukova, A., Protsenko, E., Isaeva, J., Gagloeva, V., Verbitskaya, E. V., & Sokolov, A. Y. (2022) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2022.07.05.498780
Neuroepidemiology study of headache in the region of Jammu of north Indian populationPreprint
Sudershan, A., Younis, M., Pushap, A. C., Kumar, H., Sudershan, S., & Kumar, P. (2022) · Research Square · doi:10.21203/rs.3.rs-1894878/v1
Effets sanitaires des éclairages opératoires à LED
Perez, S. (2022) · Interbloc · doi:10.1016/j.bloc.2022.08.007
On the Occasion of the Publication of the Clinical Guideline for Headache 2021 Future Prospects from the Recommendation of Acupuncture Treatment in Clinical question
KIKUCHI, T., YAMAGUCHI, S., Kubo, A., MATSUURA, Y., & Araki, N. (2022) · Zen Nihon Shinkyu Gakkai zasshi (Journal of the Japan Society of Acupuncture and Moxibustion) · doi:10.3777/jjsam.72.4
Migraines and Cortical Spreading Depression
Dahlem, M. A. (2022) · Encyclopedia of Computational Neuroscience · doi:10.1007/978-1-0716-1006-0_507

Authors: Noseda, R., Kainz, V., Jakubowski, M., Gooley, J. J., Saper, C. B., Digre, K., & Burstein, R.
Affiliations: Beth Israel Deaconess Medical Center (US)
University of Utah (US)
Harvard University (US)
Corresponding author: Burstein, Rami
ORCID: Noseda, Rodrigo
Jakubowski, Moshe
Gooley, Joshua J
Saper, Clifford B
Digre, Kathleen
Burstein, Rami
Venue: Nature Neuroscience
Publisher: Springer Science and Business Media LLC
Published: 2010-01-10
Volume: 13
Issue: 2
Pages: 239-245
ISSN: 1097-6256 (ISSN-L)
1546-1726
DOI: 10.1038/nn.2475
PMC: PMC2818758
OpenAlex: W2152412393
Cited by: 565
References: 46
Citations by year: 2026: 25 · 2025: 32 · 2024: 37 · 2023: 40 · 2022: 37 · 2021: 34 · 2020: 30 · 2019: 46 · 2018: 41 · 2017: 31 · 2016: 32 · 2015: 26 · 2014: 33 · 2013: 35 · 2012: 23
FWCI: 25.74
Type: journal article
Language: en
Open access: green
www.ncbi.nlm.nih.gov
Licence: www.springer.com/tdm (tdm)
Locations: Nature Neuroscience (publishedVersion)
PubMed (publishedVersion)
PubMed Central (acceptedVersion)
Funders: National Institute of Neurological Disorders and Stroke (R01NS051484, NS-035611, R01NS033987, P01NS035611, NS051484)
Topics: Health Sciences › Medicine › Clinical Neurology › Migraine and Headache Studies
Health Sciences › Medicine › Physiology (medical) › Pain Mechanisms and Treatments
Life Sciences › Neuroscience › Endocrine and Autonomic Systems › Circadian rhythm and melatonin
Keywords: migraine, intrinsically photosensitive retinal ganglion cells, thalamus, thalamocortical neurons, blind people, nociceptive signaling, thalamocortical connections
MeSH terms: Adult, Animals, Axons, Blindness, Cerebral Cortex, Dendrites, Dura Mater, Female, Humans, Light, Male, Migraine Disorders, Neural Pathways, Neurons, Retina, Retinal Ganglion Cells, Thalamus, Incidence, Prevalence, Rats

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

A neural mechanism for exacerbation of headache by light

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Self-check

Citations

Cites

Cited by

Related

Metadata

Record

About these checks