Saper, Clifford B.

Narcolepsy in orexin Knockout Mice

Chemelli, R. M., Willie, J. T., Sinton, C. M., Elmquist, J. K., Scammell, T., Lee, C., Richardson, J. A., Williams, S. C., Xiong, Y., Kisanuki, Y., et al. (1999) · Cell

Sleep and Wakefulness ResearchNeuroscience of respiration and sleep

Cited by 3,095

Hypothalamic regulation of sleep and circadian rhythms

Saper, C. B., Scammell, T. E., & Lu, J. (2005) · Nature

Sleep and Wakefulness ResearchCircadian rhythm and melatonin

Cited by 2,804

Differential expression of orexin receptors 1 and 2 in the rat brain

Marcus, J. N., Aschkenasi, C. J., Lee, C. E., Chemelli, R. M., Saper, C. B., Yanagisawa, M., & Elmquist, J. K. (2001) · Journal of Comparative Neurology

Sleep and Wakefulness ResearchRegulation of Appetite and Obesity

Cited by 1,659

The sleep switch: hypothalamic control of sleep and wakefulness

Saper, C. B., Chou, T. C., & Scammell, T. E. (2001) · Trends in Neurosciences

Sleep and Wakefulness ResearchNeuroscience of respiration and sleep

Cited by 1,656

Sleep state switching

Saper, C. B., Fuller, P. M., Pedersen, N. P., Lu, J., & Scammell, T. E. (2010) · Neuron

Sleep and Wakefulness ResearchNeuroscience of respiration and sleep

Cited by 1,404

From Lesions to Leptin

Elmquist, J. K., Elias, C. F., & Saper, C. B. (1999) · Neuron

Regulation of Appetite and ObesityAdipokines, Inflammation, and Metabolic Diseases

Cited by 1,160

The Need to Feed

Saper, C. B., Chou, T. C., & Elmquist, J. K. (2002) · Neuron

Regulation of Appetite and ObesityHypothalamic control of reproductive hormones

Cited by 1,120

Activation of ventrolateral preoptic neurons during sleep

Sherin, J. E., Shiromani, P. J., McCarley, R. W., & Saper, C. B. (1996) · Science

Sleep and Wakefulness ResearchNeuroscience of respiration and sleep

Cited by 1,111

Expression of ghrelin receptor mRNA in the rat and the mouse brain

Zigman, J. M., Jones, J. E., Lee, C. E., Saper, C. B., & Elmquist, J. K. (2006) · The Journal of Comparative Neurology

Regulation of Appetite and ObesityHypothalamic control of reproductive hormones

Cited by 1,074

Leptin Differentially Regulates NPY and POMC Neurons Projecting to the Lateral Hypothalamic Area

Elias, C. F., Aschkenasi, C., Lee, C., Kelly, J., Ahima, R. S., Bjorbæk, C., Flier, J. S., Saper, C. B., & Elmquist, J. K. (1999) · Neuron

Regulation of Appetite and ObesityHypothalamic control of reproductive hormones

Cited by 924

The α2-Adrenoceptor Agonist Dexmedetomidine Converges on an Endogenous Sleep-promoting Pathway to Exert Its Sedative Effects

Nelson, L. E., Lu, J., Guo, T., Saper, C. B., Franks, N. P., & Maze, M. (2003) · Anesthesiology

Sleep and Wakefulness ResearchAnesthesia and Sedative Agents

Cited by 854

The central autonomic nervous system: conscious visceral perception and autonomic pattern generation

Saper, C. B. (2002) · Annual Review of Neuroscience

Heart Rate Variability and Autonomic ControlNeuroscience of respiration and sleep

Cited by 837

Efferent projections of the infralimbic cortex of the rat

Hurley, K. M., Herbert, H., Moga, M. M., & Saper, C. B. (1991) · Journal of Comparative Neurology

Memory and Neural MechanismsNeuroscience and Neuropharmacology Research

Cited by 777

Leptin Regulation of Neuroendocrine Systems

Ahima, R. S., Saper, C. B., Flier, J. S., & Elmquist, J. K. (2000) · Frontiers in Neuroendocrinology

Regulation of Appetite and ObesityHypothalamic control of reproductive hormones

Cited by 767

Cortical projections arising from the basal forebrain: A study of cholinergic and noncholinergic components employing combined retrograde tracing and immunohistochemical localization of choline acetyltransferase

Rye, D. B., Wainer, B. H., Mesulam, M.-M., Mufson, E. J., & Saper, C. B. (1984) · Neuroscience

Neuroscience and Neuropharmacology ResearchMemory and Neural Mechanisms

Cited by 743

Evidence for a viscerotopic sensory representation in the cortex and thalamus in the rat

Cechetto, D. F., & Saper, C. B. (1987) · Journal of Comparative Neurology

Ion Channels and ReceptorsTactile and Sensory Interactions

Cited by 703

The rostromedial tegmental nucleus (RMTg), a GABAergic afferent to midbrain dopamine neurons, encodes aversive stimuli and inhibits motor responses.

Jhou, T. C., Fields, H. L., Baxter, M. G., Saper, C. B., & Holland, P. C. (2009) · Neuron

Neurotransmitter Receptor Influence on BehaviorMemory and Neural Mechanisms

Cited by 696

Fos Expression in Orexin Neurons Varies with Behavioral State

Estabrooke, I. V., McCarthy, M. T., Ko, E., Chou, T. C., Chemelli, R. M., Yanagisawa, M., Saper, C. B., & Scammell, T. E. (2001) · The Journal of Neuroscience

Sleep and Wakefulness ResearchNeuroscience of respiration and sleep

Cited by 654

Critical role of dorsomedial hypothalamic nucleus in a wide range of behavioral circadian rhythms

Chou, T. C., Scammell, T. E., Gooley, J. J., Gaus, S. E., Saper, C. B., & Lu, J. (2003) · The Journal of Neuroscience

Circadian rhythm and melatoninSleep and Wakefulness Research

Cited by 576

The sedative component of anesthesia is mediated by GABAA receptors in an endogenous sleep pathway

Nelson, L. E., Guo, T. Z., Lu, J., Saper, C. B., Franks, N. P., & Maze, M. (2002) · Nature Neuroscience

Anesthesia and Sedative AgentsSleep and Wakefulness Research

Cited by 568

A neural mechanism for exacerbation of headache by light

Noseda, R., Kainz, V., Jakubowski, M., Gooley, J. J., Saper, C. B., Digre, K., & Burstein, R. (2010) · Nature Neuroscience

Migraine and Headache StudiesPain Mechanisms and Treatments

Cited by 565

Unraveling the central nervous system pathways underlying responses to leptin

Elmquist, J. K., Maratos-Flier, E., Saper, C. B., & Flier, J. S. (1998) · Nature Neuroscience

Regulation of Appetite and ObesityAdipokines, Inflammation, and Metabolic Diseases

Cited by 520

The dorsomedial hypothalamic nucleus is critical for the expression of food-entrainable circadian rhythms

Gooley, J. J., Schomer, A., & Saper, C. B. (2006) · Nature Neuroscience

Circadian rhythm and melatoninRegulation of Appetite and Obesity

Cited by 453

Glucagon-like peptide-1 receptor stimulation increases blood pressure and heart rate and activates autonomic regulatory neurons

Yamamoto, H., Lee, C. E., Marcus, J. N., Williams, T. D., Overton, J. M., Lopez, M. E., Hollenberg, A. N., Baggio, L., Saper, C. B., Drucker, D. J., et al. (2002) · Journal of Clinical Investigation

Neuropeptides and Animal PhysiologyHeart Rate Variability and Autonomic Control

Cited by 429