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A causal link between prediction errors, dopamine neurons and learning

Steinberg, Elizabeth E, Keiflin, Ronald, Boivin, Josiah R, Witten, Ilana B, Deisseroth, Karl, Janak, Patricia H·2013·Nature Neuroscience

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Show all 14 references

Research works printed but not linked: 32

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  3. Roesch, M.R., Calu, D.J. & Schoenbaum, G. Dopamine neurons encode the better option in rats deciding between differently delayed or sized rewards. Nat. Neurosci. 10, 1615–1624 (2007). · DOI · Paper page
  4. Hollerman, J.R. & Schultz, W. Dopamine neurons report an error in the temporal prediction of reward during learning. Nat. Neurosci. 1, 304–309 (1998). · DOI · Paper page
  5. Mirenowicz, J. & Schultz, W. Importance of unpredictability for reward responses in primate dopamine neurons. J. Neurophysiol. 72, 1024–1027 (1994). · DOI · Paper page
  6. Takahashi, Y.K. et al. The orbitofrontal cortex and ventral tegmental area are necessary for learning from unexpected outcomes. Neuron 62, 269–280 (2009). · DOI · Paper page
  7. Iordanova, M.D., Westbrook, R.F. & Killcross, A.S. Dopamine activity in the nucleus accumbens modulates blocking in fear conditioning. Eur. J. Neurosci. 24, 3265–3270 (2006). · DOI
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  9. Parker, J.G. et al. Absence of NMDA receptors in dopamine neurons attenuates dopamine release, but not conditioned approach, during Pavlovian conditioning. Proc. Natl. Acad. Sci. USA 107, 13491–13496 (2010). · DOI
  10. Adamantidis, A.R. et al. Optogenetic interrogation of dopaminergic modulation of the multiple phases of reward-seeking behavior. J. Neurosci. 31, 10829–10835 (2011). · DOI · Paper page
  11. Domingos, A.I. et al. Leptin regulates the reward value of nutrient. Nat. Neurosci. 14, 1562–1568 (2011). · DOI
  12. Witten, I.B. et al. Recombinase-driver rat lines: tools, techniques, and optogenetic application to dopamine-mediated reinforcement. Neuron 72, 721–733 (2011). · DOI · Paper page
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  14. Zhang, F., Wang, L.P., Boyden, E.S. & Deisseroth, K. Channelrhodopsin-2 and optical control of excitable cells. Nat. Methods 3, 785–792 (2006). · DOI · Paper page
  15. Kamin, L.J. “Attention-like” processes in classical conditioning. in Miami Symposium on the Prediction of Behavior, 1967: Aversive Stimulation (ed. Jones, M.R.) 9–31 (University of Miami Press, 1968).
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Metadata

Authors
Steinberg, E. E., Keiflin, R., Boivin, J. R., Witten, I. B., Deisseroth, K., & Janak, P. H.
Venue
Nature Neuroscience
Published
2013-05-26
Volume
16
Issue
7
Pages
966-973
ISSN
  • 1097-6256
  • 1546-1726
Cited by
869
References
14
Language
en
Licence
www.springer.com/tdm (tdm)

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CoChat. (2026). Citation check: A causal link between prediction errors, dopamine neurons and learning. https://app.cochat.ai/papers/10.1038/nn.3413
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Steinberg, E. E., Keiflin, R., Boivin, J. R., Witten, I. B., Deisseroth, K., & Janak, P. H. (2013). A causal link between prediction errors, dopamine neurons and learning. Nature Neuroscience. https://doi.org/10.1038/nn.3413

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