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Cytokines and their relationship to the symptoms and outcome of cancer
Open accessAbstract
Tumours contain immune cells and a network of pro- and anti-inflammatory cytokines, which collaborate in the development and progression of cancer. Cytokine profiles might prove to be prognostic. The systemic effects of pro-inflammatory cytokines are associated with fatigue, depression and cognitive impairment, and can affect quality of life before, during and after treatment. In people with advanced cancer, pro-inflammatory cytokines are additionally associated with anorexia and cachexia, pain, toxicity of treatment and resistance to treatment. However, physical activity might modify cytokine levels and decrease fatigue in patients with cancer, and might also improve their prognosis.
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“The treatment of physical disorders, e.g., interferon-based or virostatic treatments for hepatitis C (167, 197), chemotherapy for the treatment of cancer (168), surgery (169) or transplantation (170), can lead to additional cytokine release.”
From Cytokine Research in Depression: Principles, Challenges, and Open Questions (2019) · cites this paper as [168]
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Cites
Coussens, L. M., & Werb, Z. (2002) · Nature · doi:10.1038/nature01322 · Cited by 15,111
Gene expression profiling predicts clinical outcome of breast cancer
van 't Veer, L. J., Dai, H., van de Vijver, M. J., He, Y. D., Hart, A. A. M., Mao, M., Peterse, H. L., van der Kooy, K., Marton, M. J., Witteveen, A. T., et al. (2002) · Nature · doi:10.1038/415530a · Cited by 9,536
Janeway, C. A., & Medzhitov, R. (2002) · Annual Review of Immunology · doi:10.1146/annurev.immunol.20.083001.084359 · Cited by 8,394
Inflammation and cancer: back to Virchow?
Balkwill, F., & Mantovani, A. (2001) · The Lancet · doi:10.1016/s0140-6736(00)04046-0 · Cited by 7,746
From inflammation to sickness and depression: when the immune system subjugates the brain
Dantzer, R., O'Connor, J. C., Freund, G. G., Johnson, R. W., & Kelley, K. W. (2008) · Nature Reviews Neuroscience · doi:10.1038/nrn2297 · Cited by 7,395
A Multigene Assay to Predict Recurrence of Tamoxifen-Treated, Node-Negative Breast Cancer
Paik, S., Shak, S., Tang, G., Kim, C., Baker, J. B., Cronin, M. T., Baehner, F. L., Walker, M. G., Watson, D., Park, T., et al. (2004) · New England Journal of Medicine · doi:10.1056/nejmoa041588 · Cited by 6,321
MANTOVANI, A., SOZZANI, S., LOCATI, M., ALLAVENA, P., & SICA, A. (2002) · Trends in Immunology · doi:10.1016/s1471-4906(02)02302-5 · Cited by 5,528
A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17
Park, H., Li, Z., Yang, X. O., Chang, S. H., Nurieva, R., Wang, Y.-H., Wang, Y., Hood, L., Zhu, Z., Tian, Q., et al. (2005) · Nature Immunology · doi:10.1038/ni1261 · Cited by 4,265
Toll-like receptor control of the adaptive immune responses
Iwasaki, A., & Medzhitov, R. M. (2004) · Nature Immunology · doi:10.1038/ni1112 · Cited by 4,166
The expanding universe of T-cell subsets: Th1, Th2 and more
Mosmann, T. R., & Sad, S. (1996) · Immunology Today · doi:10.1016/0167-5699(96)80606-2 · Cited by 3,603
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Pacheco‐López, G., & Bermúdez‐Rattoni, F. (2011) · Philosophical Transactions of the Royal Society B Biological Sciences · doi:10.1098/rstb.2011.0061 · Cited by 48
Depression as a systemic disease
Sotelo, J. L., & Nemeroff, C. B. (2016) · Personalized Medicine in Psychiatry · doi:10.1016/j.pmip.2016.11.002 · Cited by 48
Chae, J., Ng, T. R. D., Yeo, H. L., Shwe, M., Gan, Y. X., Ho, H. K., & Chan, A. (2016) · PLoS ONE · doi:10.1371/journal.pone.0164204 · Cited by 45
Marceca, G. P., Nigita, G., Calore, F., & Croce, C. M. (2020) · Frontiers in Oncology · doi:10.3389/fonc.2020.607196 · Cited by 45
Xiong, L., Liang, B., & Yu, K. (2025) · Materials Today Bio · doi:10.1016/j.mtbio.2025.102070 · Cited by 44
Elevated prefrontal myo-inositol and choline following breast cancer chemotherapy
Kesler, S. R., Watson, C., Koovakkattu, D., Lee, C. D., O'Hara, R. M., Mahaffey, M. L., & Wefel, J. S. (2013) · Brain Imaging and Behavior · doi:10.1007/s11682-013-9228-1 · Cited by 44
Rahbar, M., Wu, Y.-L., Subramony, J. A., & Liu, G. (2021) · Frontiers in Bioengineering and Biotechnology · doi:10.3389/fbioe.2021.778269 · Cited by 44
The beneficial role of exercise in mitigating doxorubicin-induced Mitochondrionopathy
Marques‐Aleixo, I., Alves, E. S., Oliveira, P. J., Moreira, P. I., Magalhães, J., & Ascensão, A. A. M. R. (2018) · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer · doi:10.1016/j.bbcan.2018.01.002 · Cited by 44
Multiplex Cytokine Concentration Measurement: How Much Do the Medium and Handling Matter?
Parkitny, L., McAuley, J. H., Kelly, P. J., Pietro, F. D., Cameron, B., & Moseley, G. L. (2013) · Mediators of Inflammation · doi:10.1155/2013/890706 · Cited by 43
Translational research and symptom management in oncology nursing
Lopes‐Júnior, L. C., Olson, K. L., Bomfim, E. D. O., Pereira-da-Silva, G., Nascimento, L. C., & de Lima, R. A. G. (2016) · British Journal of Nursing · doi:10.12968/bjon.2016.25.10.s12 · Cited by 43
Ginseng and Cancer-Related Fatigue: A Systematic Review of Clinical Trials
Sadeghian, M., Rahmani, S., Zendehdel, M., Hosseini, S. A., & Javid, A. Z. (2020) · Nutrition and Cancer · doi:10.1080/01635581.2020.1795691 · Cited by 43
Bikomeye, J. C., Beyer, A., Kwarteng, J. L., & Beyer, K. M. M. (2022) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph19042426 · Cited by 44
Cancer cachexia as a multiorgan failure: Reconstruction of the crime scene
Ferrara, M., Samaden, M., Ruggieri, E., & Vénéreau, E. (2022) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2022.960341 · Cited by 42
Resolution of inflammation in oral diseases
Eltay, E. G., & Dyke, T. E. V. (2023) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2023.108453 · Cited by 44
IL-6, cancer and cachexia: metabolic dysfunction creates the perfect storm
White, J. P. (2017) · Translational Cancer Research · doi:10.21037/tcr.2017.03.52 · Cited by 45
Molecular Mechanisms Leading from Periodontal Disease to Cancer
Sobocki, B. K., Basset, C. A., Bruhn-Olszewska, B., Olszewski, P., Szot, O., Kaźmierczak-Siedlecka, K., Guziak, M., Nibali, L., & Leone, A. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23020970 · Cited by 42
Improving muscle mass and function in cachexia
Maddocks, M. M., Murton, A. J., & Wilcock, A. (2011) · Current Opinion in Supportive and Palliative Care · doi:10.1097/spc.0b013e32834bdde3 · Cited by 41
Shimizu, T., Ishikawa, T., Iwai, S., Ueki, A., Sugihara, E., Onishi, N., Kuninaka, S., Miyamoto, T. K., Toyama, Y., Ijiri, H., et al. (2012) · Molecular Cancer Research · doi:10.1158/1541-7786.mcr-11-0347 · Cited by 41
Aouizerat, B. E., Dhruva, A., Paul, S. M., Cooper, B. A., Kober, K. M., & Miaskowski, C. A. (2015) · Journal of Pain and Symptom Management · doi:10.1016/j.jpainsymman.2015.05.008 · Cited by 41
Yao, C., Rich, J. B., Tirona, K., & Bernstein, L. J. (2016) · Psycho-Oncology · doi:10.1002/pon.4351 · Cited by 41
Self-citationLopes‐Júnior, L. C., Pereira-da-Silva, G., da Silveira, D. S. C., Veronez, L. C., dos Santos, J. C., Alonso, J. B., & de Lima, R. A. G. (2018) · Integrative Cancer Therapies · doi:10.1177/1534735418781725 · Cited by 41
Pain and Inflammation in Women With Early-Stage Breast Cancer Prior to Induction of Chemotherapy
Starkweather, A. R., Lyon, D., & Schubert, C. M. (2011) · Biological Research For Nursing · doi:10.1177/1099800411425857 · Cited by 41
Yae, S., Takahashi, F., Yae, T., Yamaguchi, T., Tsukada, R., Koike, K., Minakata, K., Murakami, A., Nurwidya, F., Kato, M., et al. (2012) · Evidence-based Complementary and Alternative Medicine · doi:10.1155/2012/976926 · Cited by 41
Wang, Y., Li, Z., Tang, F.-B., Zhang, Y., Zhou, T., Zhang, L., Ma, J., You, W., & Pan, K. (2015) · Tumor Biology · doi:10.1007/s13277-015-4022-x · Cited by 40
Oliveira, K. G., von Zeidler, S. V., Lamas, A. Z., de Podestá, J. R. V., Sena, A., Souza, E. D., Lenzi, J., Lemos, E. M., Gouvêa, S. A., & Bissoli, N. S. (2014) · Brazilian Journal of Medical and Biological Research · doi:10.1590/1414-431x20143599 · Cited by 40
Merriman, J. D., Aouizerat, B. E., Cataldo, J. K., Dunn, L. B., Cooper, B. A., West, C. M., Paul, S. M., Baggott, C., Dhruva, A., Kober, K. M., et al. (2013) · Cytokine · doi:10.1016/j.cyto.2013.11.003 · Cited by 40
Capozzi, L., Lau, H., Reimer, R. A., McNeely, M. L., Giese‐Davis, J., & Culos-Reed, S. N. (2012) · BMC Cancer · doi:10.1186/1471-2407-12-446 · Cited by 39
Benson, S., Engler, H., Wegner, A., Rebernik, L., Spreitzer, I., Schedlowski, M., & Elsenbruch, S. (2017) · Clinical Pharmacology & Therapeutics · doi:10.1002/cpt.618 · Cited by 39
Guo, S., Wang, Y., Li, Y., Li, Z., Feng, C., & Li, Z. (2020) · Immunology Letters · doi:10.1016/j.imlet.2020.03.004 · Cited by 39
Starkweather, A., Lyon, D. E., Elswick, R. K., Montpetit, A. J., Conley, Y., & McCain, N. (2013) · Current Pharmacogenomics and Personalized Medicine · doi:10.2174/18756921113119990004 · Cited by 40
Capone, F., Guerriero, E., Sorice, A., Colonna, G., Ciliberto, G., & Costantini, S. (2016) · Mediators of Inflammation · doi:10.1155/2016/3064643 · Cited by 38
Brain damage from anticancer treatments in adults
Ricard, D., Taillia, H., & Renard, J.-L. (2009) · Current Opinion in Oncology · doi:10.1097/cco.0b013e328330c669 · Cited by 38
Park, E., Park, S. J., Kim, S., Lee, K., & Chang, J. (2018) · Toxicology Letters · doi:10.1016/j.toxlet.2018.01.003 · Cited by 38
Intra-individual Variability in Women with Breast Cancer
Bernstein, L. J., Catton, P. A., & Tannock, I. F. (2014) · Journal of the International Neuropsychological Society · doi:10.1017/s1355617714000125 · Cited by 37
Self-citationBiomarkers: Symptoms, Survivorship, and Quality of Life
Miaskowski, C. A., & Aouizerat, B. E. (2012) · Seminars in Oncology Nursing · doi:10.1016/j.soncn.2012.03.008 · Cited by 37
Koshiol, J. E., Castro, F. A., Kemp, T. J., Gao, Y.-T., Roa, J. C., Wang, B., Nogueira, L., Araya, J. C., Shen, M.-C., Rashid, A., et al. (2016) · Cytokine · doi:10.1016/j.cyto.2016.05.003 · Cited by 37
“Doctor, Will the Treatment You Are Recommending Cause Chemobrain?”
Ganz, P. A. (2011) · Journal of Clinical Oncology · doi:10.1200/jco.2011.39.4288 · Cited by 37
Cellular-scale proximity labeling for recording cell spatial organization in mouse tissues
Zhang, X., Tang, Q., Sun, J., Guo, Y., Zhang, S., Liang, S., Dai, P., & Chen, X. (2023) · Science Advances · doi:10.1126/sciadv.adg6388 · Cited by 37
Wright, F., Hammer, M. J., Paul, S. M., Aouizerat, B. E., Kober, K. M., Conley, Y. P., Cooper, B. A., Dunn, L. B., Levine, J. D., Melkus, G. D., et al. (2017) · Cytokine · doi:10.1016/j.cyto.2016.12.023 · Cited by 36
Genetic variants in interleukin-6 modified risk of obstructive sleep apnea syndrome
Zhang, H. (2009) · International Journal of Molecular Medicine · doi:10.3892/ijmm_00000155 · Cited by 36
Self-citationAlfaro, E., Dhruva, A., Langford, D. J., Koetters, T., Merriman, J. D., West, C. M., Dunn, L. B., Paul, S. M., Cooper, B. A., Cataldo, J. K., et al. (2013) · European Journal of Oncology Nursing · doi:10.1016/j.ejon.2013.08.004 · Cited by 37
Oliveira, C. D. F., Lopes, D. S., Mendes, M. M., Homsi-Brandeburgo, M. I., Hamaguchi, A., Alcântara, T. M., Clissa, P. B., & Rodrigues, V. D. M. (2009) · Toxicon · doi:10.1016/j.toxicon.2008.12.025 · Cited by 36
Moreno, P. I., Moskowitz, A. L., Ganz, P. A., & Bower, J. E. (2016) · Psychosomatic Medicine · doi:10.1097/psy.0000000000000300 · Cited by 38
Henneghan, A. M., Palesh, O. G., Harrison, M., & Kesler, S. R. (2018) · Journal of Neuroimmunology · doi:10.1016/j.jneuroim.2018.04.012 · Cited by 36
Sonowal, H., Pal, P. B., Shukla, K., Saxena, A., Sk, S., & Ramana, K. V. (2018) · Biochemical Pharmacology · doi:10.1016/j.bcp.2018.02.018 · Cited by 35
Guinan, E. M., Doyle, S. L., O’Neill, L. M., Dunne, M. R., Foley, E. K., O'Sullivan, J. N., Reynolds, J. V., & Hussey, J. M. (2016) · Supportive Care in Cancer · doi:10.1007/s00520-016-3455-0 · Cited by 35
Vodermaier, A. (2009) · Women s Health · doi:10.2217/whe.09.36 · Cited by 34
Inflammatory biomarkers and emotional approach coping in men with prostate cancer
Hoyt, M. A., Stanton, A. L., Bower, J. E., Thomas, K. S., Litwin, M. S., Breen, E. C., & Irwin, M. R. (2013) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2013.04.008 · Cited by 34
Yennurajalingam, S., Williams, J. L., Chisholm, G. B., & Bruera, E. D. (2016) · The Oncologist · doi:10.1634/theoncologist.2014-0260 · Cited by 34
Koleck, T. A., Topaz, M., Tatonetti, N. P., George, M., Miaskowski, C., Smaldone, A., & Bakken, S. (2021) · Research in Nursing & Health · doi:10.1002/nur.22190 · Cited by 33
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Marceca, G. P., Tomasello, L., Distefano, R., Acunzo, M., Croce, C. M., & Nigita, G. (2021) · Cancers · doi:10.3390/cancers13071699 · Cited by 34
Symptoms: Fatigue and Cognitive Dysfunction
Bower, J. E., & Ganz, P. A. (2015) · Advances in experimental medicine and biology · doi:10.1007/978-3-319-16366-6_5 · Cited by 34
Cognitive Symptoms Across Diverse Cancers
Mayo, S. J., Edelstein, K., Atenafu, E. G., Ajaj, R., Li, M., & Bernstein, L. J. (2024) · JAMA Network Open · doi:10.1001/jamanetworkopen.2024.30833 · Cited by 32
Self-citationChemotherapy-induced cognitive impairment: focus on the intersection of oxidative stress and TNFα
Rummel, N. G., Chaiswing, L., Bondada, S., Clair, D. K. S., & Butterfield, D. A. (2021) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-021-03925-4 · Cited by 32
Reed, R. G., Weihs, K. L., Sbarra, D. A., Breen, E. C., Irwin, M. R., & Butler, E. A. (2016) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2016.02.018 · Cited by 35
Melanoma vaccines: developments over the past 10 years
Klein, O., Schmidt, C., Knights, A. J., Davis, I. D., Chen, W., & Cebon, J. S. (2011) · Expert Review of Vaccines · doi:10.1586/erv.11.74 · Cited by 31
The Role of Physical Activity in Managing Fatigue in Cancer Survivors
Ferrer, B.-C. S., van Roekel, E. H., & Lynch, B. M. (2018) · Current Nutrition Reports · doi:10.1007/s13668-018-0234-1 · Cited by 31
Cognitive complications of cancer and cancer-related treatments – Novel paradigms
Lomeli, N., Lepe, J. J., Gupta, K., & Bota, D. A. (2021) · Neuroscience Letters · doi:10.1016/j.neulet.2021.135720 · Cited by 35
Zheng, G., Chen, H., & Xiong, S.-Q. (2012) · PLoS ONE · doi:10.1371/journal.pone.0034839 · Cited by 32
Impact of chemotherapy on cancer-related fatigue and cytokines in 1312 patients
Eyob, T., Ng, T. R. D., Chan, R. J., & Chan, A. (2016) · Current Opinion in Supportive and Palliative Care · doi:10.1097/spc.0000000000000205 · Cited by 31
Merriman, J. D., Aouizerat, B. E., Langford, D. J., Cooper, B. A., Baggott, C., Cataldo, J. K., Dhruva, A., Dunn, L. B., West, C. M., Paul, S. M., et al. (2013) · Biological Research For Nursing · doi:10.1177/1099800413479441 · Cited by 30
Laviano, A., Seelaender, M. C. L., Sánchez-Lara, K., Gioulbasanis, I., Molfino, A., & Fanelli, F. R. (2011) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2011.06.060 · Cited by 30
Saad, S. A., Dunn, L. B., Koetters, T., Dhruva, A., Langford, D. J., Merriman, J. D., West, C. M., Paul, S. M., Cooper, B. A., Cataldo, J. K., et al. (2014) · European Journal of Oncology Nursing · doi:10.1016/j.ejon.2014.03.009 · Cited by 30
Delivering cytokines at tumor site: The immunocytokine-conjugated anti-EDB-fibronectin antibody case
Ronca, R., Sozzani, S., Presta, M., & Alessi, P. (2009) · Immunobiology · doi:10.1016/j.imbio.2009.06.005 · Cited by 30
Challenge of managing cancer-related fatigue.
Bruera, E., & Yennurajalingam, S. (2010) · Journal of Clinical Oncology · doi:10.1200/jco.2010.29.8984 · Cited by 31
Li, H., Jin, X., Ng, M. S. N., Mann, K. F., Wang, N., & Wong, C. L. (2022) · Asia-Pacific Journal of Oncology Nursing · doi:10.1016/j.apjon.2022.100102 · Cited by 29
“Patients meeting the following inclusion criteria were invited to participate in this study: (1) aged 18 years or older; (2) diagnosed with stage III/IV lung cancer through pathological section or cytology; (3) had experienced unexplained fatigue syndrome, with a score of 3 or higher in the Fatigue Symptom Inventory (…”
MethodCognitive Dysfunction after Chemotherapy For Breast Cancer
Edelstein, K., & Bernstein, L. J. (2014) · Journal of the International Neuropsychological Society · doi:10.1017/s1355617714000149 · Cited by 29
Self-citationCurrow, D. C., Higginson, I. J., & Johnson, M. J. (2013) · Palliative Medicine · doi:10.1177/0269216313493819 · Cited by 29
Miaskowski, C. A., Cataldo, J. K., Baggott, C., West, C. M., Dunn, L. B., Dhruva, A., Merriman, J. D., Langford, D. J., Kober, K. M., Paul, S. M., et al. (2014) · Supportive Care in Cancer · doi:10.1007/s00520-014-2443-5 · Cited by 30
ShenQi FuZheng Injection ameliorates fatigue-like behavior in mouse models of cancer-related fatigue
Zhu, G., Zhang, B., Jiang, F., Zhao, L., & Liu, F. (2019) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2019.01.042 · Cited by 29
Chou, H.-L., Chao, T.-Y., Chen, T., Chu, C., Hsieh, C.-H., Yao, C.-T., & Janckila, A. J. (2016) · Cancer Nursing · doi:10.1097/ncc.0000000000000369 · Cited by 28
Psychoneuroimmunology and oncology nursing: a theoretical study
Lopes‐Júnior, L. C., Tuma, M. C., & Amorim, M. H. C. (2021) · Revista da Escola de Enfermagem da USP · doi:10.1590/1980-220x-reeusp-2021-0159 · Cited by 28
Kuzu, B., Hepokur, C., Alagöz, M. A., Burmaoğlu, S., & Algül, Ö. (2022) · ChemistrySelect · doi:10.1002/slct.202103559 · Cited by 28
Thomas, D. R. (2009) · Drugs & Aging · doi:10.2165/11316360-000000000-00000 · Cited by 28
Omega-3 Fatty Acids for Prevention of Breast Cancer: an Update and the State of the Science
Iyengar, N. M., Hudis, C. A., & Gucalp, A. (2013) · Current Breast Cancer Reports · doi:10.1007/s12609-013-0112-1 · Cited by 28
The value of quality-of-life questionnaires in head and neck cancer
Leeuw, I. M. V., van Nieuwenhuizen, A. J., & Leemans, C. R. (2012) · Current Opinion in Otolaryngology & Head & Neck Surgery · doi:10.1097/moo.0b013e32834f5fd7 · Cited by 28
Significant decline in anticancer immune capacity during puberty in the Tasmanian devil
Cheng, Y., Heasman, K., Peck, S., Peel, E., Gooley, R. M., Papenfuss, A. T., Hogg, C. J., & Belov, K. (2017) · Scientific Reports · doi:10.1038/srep44716 · Cited by 28
Chronic Systemic Symptoms in Head and Neck Cancer Patients
Murphy, B. A., Wulff-Burchfield, E. M., Ghiam, M. K., Bond, S. M., & Deng, J. F. (2019) · JNCI Monographs · doi:10.1093/jncimonographs/lgz004 · Cited by 28
Chemotherapy-induced anorexia is accompanied by activation of brain pathways signaling dehydration
Sinno, M. H., Coquerel, Q., Boukhettala, N., Coëffier, M., Gallas, S., Terashi, M., Ibrahim, A. B., Breuillé, D., Déchelotte, P., & Fetissov, S. O. (2010) · Physiology & Behavior · doi:10.1016/j.physbeh.2010.09.016 · Cited by 31
CCL2 influences the sensitivity of lung cancer A549 cells to docetaxel
Wang, T., Zhan, Q., Peng, X., Qiu, Z., & Zhao, T. (2018) · Oncology Letters · doi:10.3892/ol.2018.8769 · Cited by 27
Avisar, A., Cohen, M. W., Katz, R., Kutiel, T. S., Aharon, A., & Bar‐Sela, G. (2020) · Pharmaceuticals · doi:10.3390/ph13060129 · Cited by 27
Gutenkunst, S. L., Vardy, J. L., Dhillon, H. M., & Bell, M. L. (2020) · Supportive Care in Cancer · doi:10.1007/s00520-020-05616-5 · Cited by 27
Exercise as a therapy for cancer-induced muscle wasting
Halle, J. L., Counts, B. R., & Carson, J. A. (2020) · Sports Medicine and Health Science · doi:10.1016/j.smhs.2020.11.004 · Cited by 28
Tumor and Peripheral Immune Status in Soft Tissue Sarcoma: Implications for Immunotherapy
Sousa, L. M., Almeida, J. S., Fortes-Andrade, T., Santos-Rosa, M., Freitas-Tavares, P., Casanova, J., & Rodrigues‐Santos, P. (2021) · Cancers · doi:10.3390/cancers13153885 · Cited by 27
Razeghian, E., Margiana, R., Chupradit, S., Bokov, D. O., Abdelbasset, W. K., Marofi, F., Shariatzadeh, S., Tosan, F., & Jarahian, M. (2021) · Frontiers in Medicine · doi:10.3389/fmed.2021.721174 · Cited by 27
RetractedHussey, C., & Gupta, A. (2022) · Cancer Investigation · doi:10.1080/07357907.2022.2105349 · Cited by 27
Associations between Plasma Cytokines and Depressive Mood in Patients with Breast Cancer
Kim, S.-Y., Kim, J., Kim, S., Shin, I., Park, M., Yoon, J.-H., Choi, C., & Yoon, J. (2012) · The International Journal of Psychiatry in Medicine · doi:10.2190/pm.43.1.a · Cited by 27
England, B. R., Sokolove, J. B., Robinson, W. H., Thiele, G. M., Ganti, A. K., Sayles, H. R., Michaud, K. D., Caplan, L., Davis, L. A., Cannon, G. W., et al. (2016) · Arthritis & Rheumatology · doi:10.1002/art.39735 · Cited by 27
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Ukah, T., Cattin-Roy, A. N., Chen, W., Miller, M. M., Barik, S., & Zaghouani, H. (2017) · The Journal of Immunology · doi:10.4049/jimmunol.1700410 · Cited by 27
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Metadata
- Authors
- Seruga, B., Zhang, H., Bernstein, L. J., & Tannock, I. F.
- Affiliations
- St. Michael's Hospital (CA)
- Corresponding author
- Tannock, Ian F.
- Venue
- Nature Reviews Cancer
- Published
- 2008-10-10
- Volume
- 8
- Issue
- 11
- Pages
- 887-899
- ISSN
- 1474-175X (ISSN-L)
- 1474-1768
- OpenAlex
- W2061366514
- Cited by
- 652
- References
- 248
- Citations by year
- 2026: 11 · 2025: 23 · 2024: 35 · 2023: 26 · 2022: 37 · 2021: 47 · 2020: 33 · 2019: 33 · 2018: 45 · 2017: 33 · 2016: 48 · 2015: 41 · 2014: 45 · 2013: 45 · 2012: 60
- FWCI
- 3.26
- Type
- journal article
- Language
- en
- Open access
- green
- hdl.handle.net
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Nature reviews. Cancer (publishedVersion)
- PubMed (publishedVersion)
- TSpace (University of Toronto) (submittedVersion)
- Topics
- Health Sciences › Medicine › Physiology (medical) › Nutrition and Health in Aging
- Life Sciences › Neuroscience › Biological Psychiatry › Tryptophan and brain disorders
- Health Sciences › Medicine › Oncology › Inflammatory Biomarkers in Disease Prognosis
- Keywords
- inflammatory cytokines, advanced cancer, cancer-related fatigue, cancer cachexia, anorexia, cancer pain, depression, cognitive impairment, treatment toxicity, treatment resistance, tumor immune microenvironment, quality of life, physical activity, cytokine signaling pathways
- MeSH terms
- Anorexia, Cachexia, Depressive Disorder, Humans, Neoplasms, Cytokines
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