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Cited by 1,285

The DOI matches its Crossref record; 11 of the 11 references it cites were found in a registry or an index.

Cancer to bone: a fatal attraction

Open access
Weilbaecher, Katherine N., Guise, Theresa A., McCauley, Laurie K.·2011·Nature Reviews Cancer

Abstract

When cancer metastasizes to bone, considerable pain and deregulated bone remodelling occurs, greatly diminishing the possibility of cure. Metastasizing tumour cells mobilize and sculpt the bone microenvironment to enhance tumour growth and to promote bone invasion. Understanding the crucial components of the bone microenvironment that influence tumour localization, along with the tumour-derived factors that modulate cellular and protein matrix components of bone to favour tumour expansion and invasion, is central to the pathophysiology of bone metastases. Basic findings of tumour–bone interactions have uncovered numerous therapeutic opportunities that focus on the bone microenvironment to prevent and treat bone metastases.

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Metadata

Authors
Weilbaecher, K. N., Guise, T. A., & McCauley, L. K.
Venue
Nature Reviews Cancer
Published
2011-05-19
Volume
11
Issue
6
Pages
411-425
ISSN
  • 1474-175X (ISSN-L)
  • 1474-1768
OpenAlex
W2003213153
Cited by
1,285
References
11
FWCI
6.69
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: Cancer to bone: a fatal attraction. https://app.cochat.ai/papers/10.1038/nrc3055
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Weilbaecher, K. N., Guise, T. A., & McCauley, L. K. (2011). Cancer to bone: a fatal attraction. Nature Reviews Cancer. https://doi.org/10.1038/nrc3055

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.