Translational biology of osteosarcoma

Safety and activity of anti-PD-L1 antibody in patients with advanced cancer

Brahmer, J. R., Tykodi, S. S., Chow, L. Q. M., Hwu, W.-J., Topalian, S. L., Hwu, P., Drake, C. G., Camacho, L. H., Kauh, J., Odunsi, K., et al. (2012) · New England Journal of Medicine · doi:10.1056/nejmoa1200694 · Cited by 7,945

Cancer Immunoediting: Integrating Immunity’s Roles in Cancer Suppression and Promotion

Schreiber, R. D., Old, L. J., & Smyth, M. J. (2011) · Science · doi:10.1126/science.1203486 · Cited by 6,474

Sipuleucel-T Immunotherapy for Castration-Resistant Prostate Cancer

Kantoff, P. W., Higano, C. S., Shore, N. D., Berger, E. R., Small, E. J., Penson, D. F., Redfern, C. H., Ferrari, A. C., Dreicer, R., Sims, R. B., et al. (2010) · New England Journal of Medicine · doi:10.1056/nejmoa1001294 · Cited by 5,572

OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph node organogenesis.

Kong, Y.-Y., Yoshida, H., Sarosi, I., Tan, H.-L., Timms, E., Capparelli, C., Morony, S., Oliveira-dos-Santos, A. J., Van, G., Itie, A., et al. (1999) · Nature · doi:10.1038/16852 · Cited by 3,351

Immunogenic Cell Death in Cancer Therapy

Kroemer, G., Galluzzi, L., Kepp, O., & Zitvogel, L. (2013) · Annual Review of Immunology · doi:10.1146/annurev-immunol-032712-100008 · Cited by 3,303

WHO Classification of Tumours of Soft Tissue and Bone: WHO Classification of Tumours, vol. 5

Fletcher, C. D. �., Bridge, J., Hogendoorn, P. C. W., & Mertens, F. (2013) · Cited by 3,072

WHO classification of tumours of soft tissue and bone

Fletcher, C. D. �. (2013) · Cited by 2,874

Massive genomic rearrangement acquired in a single catastrophic event during cancer development

Stephens, P. J., Greenman, C. D., Fu, B., Yang, F., Bignell, G. R., Mudie, L. J., Pleasance, E. D., Lau, K. W., Beare, D., Stebbings, L. A., et al. (2011) · Cell · doi:10.1016/j.cell.2010.11.055 · Cited by 2,414

Immunological aspects of cancer chemotherapy

Zitvogel, L., Apetoh, L., Ghiringhelli, F., & Kroemer, G. (2008) · Nature Reviews Immunology · doi:10.1038/nri2216 · Cited by 1,712

RANK is essential for osteoclast and lymph node development.

Dougall, W. C., Glaccum, M., Charrier, K., Rohrbach, K., Brasel, K., De Smedt, T., Daro, E., Smith, J., Tometsko, M. E., Maliszewski, C. R., et al. (1999) · Genes & Development · doi:10.1101/gad.13.18.2412 · Cited by 1,478

CEMIP Promotes Osteosarcoma Progression and Metastasis Through Activating Notch Signaling Pathway

Cheng, J., Zhang, Y., Wan, R., Zhou, J., Wu, X., Fan, Q., He, J., Tan, W., & Deng, Y. (2022) · Frontiers in Oncology · doi:10.3389/fonc.2022.919108 · Cited by 24

Identification of LARS as an essential gene for osteosarcoma proliferation through large-Scale CRISPR-Cas9 screening database and experimental verification

Chen, W., Lin, Y., Jiang, M.-C., Wang, Q., & Shu, Q. (2022) · Journal of Translational Medicine · doi:10.1186/s12967-022-03571-9 · Cited by 24

P2RX7 promotes osteosarcoma progression and glucose metabolism by enhancing c-Myc stabilization

Sheng, G., Gao, Y., Ding, Q., Zhang, R., Wang, T., Jing, S., Zhao, H., Ma, T., Wu, H. K., & Yang, Y. (2023) · Journal of Translational Medicine · doi:10.1186/s12967-023-03985-z · Cited by 24

Piperine improves the sensitivity of osteosarcoma cells to doxorubicin by inducing apoptosis and inhibiting the PI3K/AKT/GSK-3β pathway

Qi, Y., Yao, L., Liu, J., & Wang, W. (2023) · Journal of Orthopaedic Surgery and Research · doi:10.1186/s13018-023-03642-7 · Cited by 24

mTORC1 Maintains the Tumorigenicity of SSEA-4+ High-Grade Osteosarcoma

Zhang, W., Ding, M., Zhang, J.-N., Qiu, J.-R., Shen, Y., Ding, X.-Y., Deng, L., Zhang, W., & Zhu, J. (2015) · Scientific Reports · doi:10.1038/srep09604 · Cited by 24

Preclinical Testing of an Oncolytic Parvovirus: Standard Protoparvovirus H-1PV Efficiently Induces Osteosarcoma Cell Lysis In Vitro

Geiß, C., Kis, Z., Leuchs, B., Frank-Stöhr, M., Schlehofer, J. R., Rommelaere, J., Dinsart, C., & Lacroix, J. (2017) · Viruses · doi:10.3390/v9100301 · Cited by 24

Utilization of targeted near-infrared molecular imaging to improve pulmonary metastasectomy of osteosarcomas

Predina, J. D., Newton, A. D., Deshpande, C. G., Low, P. S., & Singhal, S. K. (2018) · Journal of Biomedical Optics · doi:10.1117/1.jbo.23.1.016005 · Cited by 24

Arecoline suppresses RANKL-induced osteoclast differentiation in vitro and attenuates LPS-induced bone loss in vivo

Liu, F.-L., Chen, C., Lai, C., Lee, C., & Chang, D. (2020) · Phytomedicine · doi:10.1016/j.phymed.2020.153195 · Cited by 24

Oridonin enhances antitumor effects of doxorubicin in human osteosarcoma cells

Kazantseva, L., Becerra, J., & Santos‐Ruiz, L. (2021) · Pharmacological Reports · doi:10.1007/s43440-021-00324-1 · Cited by 24

Detection and surveillance of circulating tumor cells in osteosarcoma for predicting therapy response and prognosis

Mu, H., Zuo, D., Chen, J., Liu, Z., Wang, Z., Yang, L., Shi, Q., & Hua, Y. (2022) · Cancer Biology & Medicine · doi:10.20892/j.issn.2095-3941.2022.0279 · Cited by 23

Biomaterials‐Boosted Immunotherapy for Osteosarcoma

Sun, C., Li, S., & Ding, J. (2024) · Advanced Healthcare Materials · doi:10.1002/adhm.202400864 · Cited by 25

Revolutionizing Bone Regeneration: Vascularized Bone Tissue Engineering with Advanced 3D Printing Technology

Fan, J., Ding, Z., Cai, Y., Lai, Y., Huang, C. B., Jiang, B., Zhou, Z., & Luo, Z. (2025) · Aggregate · doi:10.1002/agt2.731 · Cited by 24

Aberrant expression of microRNA-99a and its target gene mTOR associated with malignant progression and poor prognosis in patients with osteosarcoma

Zhao, J., Chen, F., Zhou, Q., Pan, W., Wang, X., Xu, J., Li, N., & Yang, H. (2016) · OncoTargets and Therapy · doi:10.2147/ott.s102421 · Cited by 23

Osteosarcoma in the Post Genome Era: Preclinical Models and Approaches to Identify Tractable Therapeutic Targets

Castillo‐Tandazo, W., Mutsaers, A. J., & Walkley, C. R. (2019) · Current Osteoporosis Reports · doi:10.1007/s11914-019-00534-w · Cited by 23

Silencing of Long Non-Coding RNA LINC00607 Prevents Tumor Proliferation of Osteosarcoma by Acting as a Sponge of miR-607 to Downregulate E2F6

Zheng, Y., Chen, Z., Zhou, Z., Xu, X., & Yang, H. (2021) · Frontiers in Oncology · doi:10.3389/fonc.2020.584452 · Cited by 23

Cancer combination therapies by silencing of CTLA‐4, PD‐L1, and TIM3 in osteosarcoma

Sorkhabi, A. D., Sarkesh, A., Fotouhi, A., Saeedi, H., & Maleki, L. A. (2022) · IUBMB Life · doi:10.1002/iub.2655 · Cited by 23

Surface defect engineered-Mg-based implants enable the dual functions of superhydrophobic and synergetic photothermal/chemodynamic therapy

Zhang, D., Xu, R., Chen, S., Du, H., Shi, Q., Peng, F., & Liu, X. (2023) · Bioactive Materials · doi:10.1016/j.bioactmat.2023.07.012 · Cited by 23

A bibliometric and visualized analysis of nanoparticles in musculoskeletal diseases (from 2013 to 2023)

Cao, S., Wei, Y., Yao, Z., Yue, Y., Deng, J., Xu, H., Sheng, W., Yu, F., Liu, P., Xiong, A., et al. (2023) · Computers in Biology and Medicine · doi:10.1016/j.compbiomed.2023.107867 · Cited by 23

Methionine intervention induces PD-L1 expression to enhance the immune checkpoint therapy response in MTAP-deleted osteosarcoma

Mu, H., Zhang, Q., Zuo, D., Wang, J., Tao, Y., Li, Z., He, X., Meng, H., Wang, H., Shen, J., et al. (2025) · Cell Reports Medicine · doi:10.1016/j.xcrm.2025.101977 · Cited by 25

RBEL1 is required for osteosarcoma cell proliferation via inhibiting retinoblastoma 1

TANG, H., Ji, F., Sun, J., Xie, Y., Xu, Y.-Y., & Yue, H.-T. (2015) · Molecular Medicine Reports · doi:10.3892/mmr.2015.4670 · Cited by 23

miR-26a suppresses osteosarcoma migration and invasion by directly targeting HMGA1

Liu, J., Bo, M., Wang, Y., Shi, C., Mi, X., Lu, Y., & Yu, P. (2018) · Oncology Letters · doi:10.3892/ol.2018.8359 · Cited by 23

Immunohistochemical detection of p53, PTEN, Rb, and p16 in canine osteosarcoma using tissue microarray

Russell, D. S., Jaworski, L., & Kisseberth, W. C. (2018) · Journal of Veterinary Diagnostic Investigation · doi:10.1177/1040638718770239 · Cited by 23

Fisetin Suppresses Human Osteosarcoma U-2 OS Cell Migration and InvasionviaAffecting FAK, uPA and NF-ĸB Signaling PathwayIn Vitro

Chen, J.-K., Peng, S., Lai, K., Liu, H., Huang, Y., Lin, C.-C., Huang, A., Chueh, F., & Chung, J. (2019) · In Vivo · doi:10.21873/invivo.11542 · Cited by 23

Alendronate Functionalized Mesoporous Bioactive Glass Nanospheres

Boanini, E., Panseri, S., Arroyo, F., Montesi, M., Rubini, K., Tampieri, A., Covarrubias, C., & Bigi, A. (2016) · Materials · doi:10.3390/ma9030135 · Cited by 23

Osteosarcoma immune microenvironment: cellular struggle and novel therapeutic insights

Zhang, Y., Jiang, S., Lv, J., Feng, W., Yu, Y., & Zhao, H. (2025) · Frontiers in Immunology · doi:10.3389/fimmu.2025.1584450 · Cited by 22

MicroRNA-29a suppresses the invasion and migration of osteosarcoma cells by regulating the SOCS1/NF-κB signalling pathway through negatively targeting DNMT3B

Gong, H., Tao, Y., Mao, X., Song, D., You, D., & Ni, J. (2019) · International Journal of Molecular Medicine · doi:10.3892/ijmm.2019.4287 · Cited by 22

Successive Osteosarcoma Relapses after the First Line O2006/Sarcome-09 Trial: What Can We Learn for Further Phase-II Trials?

Thébault, É., Piperno-Neumann, S., Tran, D., Pacquement, H., Marec‐Bérard, P., Lervat, C., Castex, M., Cleirec, M., Bompas, E., Vannier, J., et al. (2021) · Cancers · doi:10.3390/cancers13071683 · Cited by 22

Investigating Optimal Chemotherapy Options for Osteosarcoma Patients through a Mathematical Model

Le, T., Su, S., & Shahriyari, L. (2021) · Cells · doi:10.3390/cells10082009 · Cited by 22

Zinc curcumin complex on fluoride doped hydroxyapatite with enhanced biological properties for dental and orthopedic applications

Bhattacharjee, A., & Bose, S. (2022) · Journal of materials research/Pratt's guide to venture capital sources · doi:10.1557/s43578-022-00595-1 · Cited by 22

Circular RNA circEMB promotes osteosarcoma progression and metastasis by sponging miR-3184-5p and regulating EGFR expression

Tan, J., Yang, B., Zhong, H., Luo, M., Su, Z., Xie, C. L., Shi, M., Sun, C., & Lin, L. (2023) · Biomarker Research · doi:10.1186/s40364-022-00442-9 · Cited by 22

Hypoxia‐Inducible Factor‐2α Signaling in the Skeletal System

Mendoza, S. V., Genetos, D. C., & Yellowley, C. E. (2023) · JBMR Plus · doi:10.1002/jbm4.10733 · Cited by 25

Oncogenes and Methionine Addiction of Cancer: Role ofc-MYC

AOKI, Y., Han, Q., Kubota, Y., MASAKI, N., Obara, K., Tome, Y., Bouvet, M., Nishida, K., & Hoffman, R. M. (2023) · Cancer Genomics & Proteomics · doi:10.21873/cgp.20371 · Cited by 22

Exosome-Based Liquid Biopsy Approaches in Bone and Soft Tissue Sarcomas: Review of the Literature, Prospectives, and Hopes for Clinical Application

Agnoletto, C., Pignochino, Y., Caruso, C., & Garofalo, C. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24065159 · Cited by 22

Calcium-based biomaterials: Unveiling features and expanding applications in osteosarcoma treatment

Wu, Y., Cheng, M., Jiang, Y., Zhang, X., Li, J., Zhu, Y., & Yao, Q. (2023) · Bioactive Materials · doi:10.1016/j.bioactmat.2023.10.008 · Cited by 22

Augmenting L3MBTL2-induced condensates suppresses tumor growth in osteosarcoma

Zhong, L., Wang, J., Chen, W., Lv, D., Zhang, R., Wang, X., Zeng, C., He, X., Zheng, L., Gao, Y., et al. (2023) · Science Advances · doi:10.1126/sciadv.adi0889 · Cited by 22

Calcium peroxide nanoparticles induce endoplasmic reticulum stress for enhanced radiation therapy of osteosarcoma

Liu, Z., Fu, Z., Zhao, M., Wang, H., Ji, X., Zhou, J., Gu, W., Gu, Y., Ni, D., & Tang, W. (2024) · Nano Today · doi:10.1016/j.nantod.2023.102136 · Cited by 22

Exosomes derived from pulmonary metastatic sites enhance osteosarcoma lung metastasis by transferring the miR-194/215 cluster targeting MARCKS

Yu, P., Han, Y., Meng, L., Tian, Y., Jin, Z., Luo, J. F., Han, C. Q., Xu, W., Kong, L., & Zhang, C. (2024) · Acta Pharmaceutica Sinica B · doi:10.1016/j.apsb.2024.01.016 · Cited by 22

Injectable Magnetic Hydrogel Filler for Synergistic Bone Tumor Hyperthermia Chemotherapy

Hu, P., Lu, J., Li, C., He, Z., Wang, X., Pan, Y., & Zhao, L. (2024) · ACS Applied Bio Materials · doi:10.1021/acsabm.3c01074 · Cited by 22

Investigating the synergy of Shikonin and Valproic acid in inducing apoptosis of osteosarcoma cells via ROS-mediated EGR1 expression

Chen, Z., Wu, F., Li, J., Dong, J.-B., He, H., Li, X.-F., Lu, Q., Zhang, W.-X., Shao, C., Yao, Z.-N., et al. (2024) · Phytomedicine · doi:10.1016/j.phymed.2024.155459 · Cited by 22

Intraoperative Resection Guidance and Rapid Pathological Diagnosis of Osteosarcoma using B7H3 Targeted Probe under NIR‐II Fluorescence Imaging

Zeng, F., Li, C., Wang, H., Wang, Y., Ren, T., He, F., Jiang, J., Xu, J., Wang, B., Wu, Y., et al. (2024) · Advanced Science · doi:10.1002/advs.202310167 · Cited by 23

Identification of Key Genes and miRNAs in Osteosarcoma Patients with Chemoresistance by Bioinformatics Analysis

Xie, B., Li, Y., Zhao, R., Xu, Y., Wu, Y., Wang, J., Xia, D., Han, W., & Chen, D. (2018) · BioMed Research International · doi:10.1155/2018/4761064 · Cited by 22

Human p21-activated kinase 5 (PAK5) expression and potential mechanisms in relevant cancers: Basic and clinical perspectives for molecular cancer therapeutics

Li, Y., Zou, J., Ye, D., Zeng, Y., Chen, C.-Y., Luo, G., & Zeng, X. (2019) · Life Sciences · doi:10.1016/j.lfs.2019.117113 · Cited by 22

Identification of tumorigenicity-associated genes in osteosarcoma cell lines based on bioinformatic analysis and experimental validation

Jiang, S., Zhou, F., Zhang, Y., Zhou, W., Zhu, L., Zhang, M., Luo, J., Ma, R., Xu, X., Zhu, J., et al. (2020) · Journal of Cancer · doi:10.7150/jca.37393 · Cited by 22

Effects of vitamin C on osteoblast proliferation and osteosarcoma inhibition using plasma coated hydroxyapatite on titanium implants

Sarkar, N., Morton, H., & Bose, S. (2020) · Surface and Coatings Technology · doi:10.1016/j.surfcoat.2020.125793 · Cited by 22

Downregulation of miR-22 Contributes to Epithelial-Mesenchymal Transition in Osteosarcoma by Targeting Twist1

Zhu, S., Wang, X., Wang, J., Xi, G.-H., & Liu, Y. (2020) · Frontiers in Oncology · doi:10.3389/fonc.2020.00406 · Cited by 22

Prognostic Factors in Patients With Osteosarcoma With the Surveillance, Epidemiology, and End Results Database

Fu, P., Shi, Y., Chen, G., Fan, Y., Gu, Y., & Gao, Z. (2020) · Technology in Cancer Research & Treatment · doi:10.1177/1533033820947701 · Cited by 22

MicroRNA-761 suppresses tumor progression in osteosarcoma via negatively regulating ALDH1B1

Wang, X., Li, C., Yao, W., Tian, Z., Liu, Z., & Ge, H. (2020) · Life Sciences · doi:10.1016/j.lfs.2020.118544 · Cited by 22

Circular RNA Circ-03955 Promotes Epithelial-Mesenchymal Transition in Osteosarcoma by Regulating miR-3662/Metadherin Pathway

Wang, Z., Deng, M., Chen, L., Wang, W., Liu, G., Liu, D., Han, Z., & Zhou, Y. (2020) · Frontiers in Oncology · doi:10.3389/fonc.2020.545460 · Cited by 22

Verteporfin Inhibits the Progression of Spontaneous Osteosarcoma Caused by Trp53 and Rb1 Deficiency in Ctsk-Expressing Cells via Impeding Hippo Pathway

Li, Y., Yang, S., & Yang, S. (2022) · Cells · doi:10.3390/cells11081361 · Cited by 22

The Rb1 tumour suppressor gene modifies telomeric chromatin architecture by regulating TERRA expression

González-Vasconcellos, I., Schneider, R., Anastasov, N., Alonso-Rodríguez, S., Sanli-Bonazzi, B., Fernández, J. L., & Atkinson, M. J. (2017) · Scientific Reports · doi:10.1038/srep42056 · Cited by 23

Histone deacetylase 6 regulated expression of IL-8 is involved in the doxorubicin (Dox) resistance of osteosarcoma cells via modulating ABCB1 transcription

Cheng, M., Cai, W., Huang, W., Chen, Y. X., Wu, Z., Luo, P., & Yan, W. (2018) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2018.09.032 · Cited by 22

Single nucleotide polymorphism of hsa-miR-124a affects risk and prognosis of osteosarcoma

Shi, Z.-W., Wang, J.-L., Zhao, N., Guan, Y., & He, W. (2016) · Cancer Biomarkers · doi:10.3233/cbm-160637 · Cited by 21

Up-Regulation of Long Noncoding RNA CCAL Predicts Poor Patient Prognosis and Promotes Tumor Metastasis in Osteosarcoma

Zhou, D., Yang, X., Li, H., Yang, Y., Zhen-jun, Z., & Wu, N. (2016) · The International Journal of Biological Markers · doi:10.5301/jbm.5000240 · Cited by 21

The Simultaneous Inhibitory Effect of Niclosamide on RANKL-Induced Osteoclast Formation and Osteoblast Differentiation

Liu, F.-L., Chen, C., Lee, C.-C., Wu, C.-C., Hsu, T.-H., Tsai, C., Huang, H., & Chang, D. (2017) · International Journal of Medical Sciences · doi:10.7150/ijms.19268 · Cited by 21

TRIM37 promotes tumor cell proliferation and drug resistance in pediatric osteosarcoma

Tao, Y., Xin, M., Cheng, H.-C., Huang, Z., Hu, T., Zhang, T., & Wang, J. (2017) · Oncology Letters · doi:10.3892/ol.2017.7059 · Cited by 21

MicroRNA-136 functions as a tumor suppressor in osteosarcoma via regulating metadherin

Guo, T., & Pan, G.-B. (2018) · Cancer Biomarkers · doi:10.3233/cbm-170970 · Cited by 21

Wogonin Influences Osteosarcoma Stem Cell Stemness Through ROS-dependent Signaling

Koh, H., Sun, H., Xing, Z., Liu, R., Chandimali, N., Kwon, T., & Lee, D. (2020) · In Vivo · doi:10.21873/invivo.11878 · Cited by 21

Discovery of Potent and Orally Bioavailable Platelet-Derived Growth Factor Receptor (PDGFR) Inhibitors for the Treatment of Osteosarcoma

Chen, X., Liu, L., Liu, P., Chen, Y., Lin, D., Yan, H., Qi, Y., Wang, Y., Qiu, Y., Fang, B., et al. (2022) · Journal of Medicinal Chemistry · doi:10.1021/acs.jmedchem.1c01732 · Cited by 21

Multifunctional mesoporous silica nanoparticles for pH-response and photothermy enhanced osteosarcoma therapy

Shi, Q., Lu, Y., Zhang, G., Yang, X. Y., Li, R., Zhang, G., Guo, X., Song, J., & Ding, Q. (2022) · Colloids and Surfaces B Biointerfaces · doi:10.1016/j.colsurfb.2022.112615 · Cited by 21

Chitosan targets PI3K/Akt/FoxO3a axis to up-regulate FAM172A and suppress MAPK/ERK pathway to exert anti-tumor effect in osteosarcoma

Ren, Z., Xiao, W., He, M., & Bai, L. (2023) · Chemico-Biological Interactions · doi:10.1016/j.cbi.2023.110354 · Cited by 21

Schottky Heterojunction Facilitates Osteosarcoma Ferroptosis and Enhances Bone Formation in a Switchable Mode

Lv, Z., Wu, Y., Lin, J., Li, W., Weisbecker, H., Wang, P., Song, X., Sun, W. Y., Sun, Z., Xie, Y., et al. (2023) · Advanced Functional Materials · doi:10.1002/adfm.202312032 · Cited by 22

Upregulation of ALDH1B1 promotes tumor progression in osteosarcoma

Wang, X., Yu, Y. H., He, Y., Cai, Q., Gao, S., Yao, W., Liu, Z., Tian, Z., Han, Q., Wang, W., et al. (2017) · Oncotarget · doi:10.18632/oncotarget.23506 · Cited by 21

miR‑590‑5p suppresses osteosarcoma cell proliferation and invasion via targeting KLF5

Cai, W., Xu, Y., Yin, J., Zuo, W., & Su, Z. Z. (2018) · Molecular Medicine Reports · doi:10.3892/mmr.2018.9173 · Cited by 21

2-Bromopalmitate sensitizes osteosarcoma cells to adriamycin-induced apoptosis via the modulation of CHOP

Xu, T., Huang, C., Qi, X., Yang, X., Zhang, N., Cao, J., Wang, C., Zhu, H., Yang, B., He, Q., et al. (2018) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2018.12.019 · Cited by 21

MicroRNA-206 Reduces Osteosarcoma Cell MalignancyIn Vitroby Targeting the PAX3-MET Axis

Zhan, F., Zhang, X.-W., Feng, S.-L., Cheng, J., Zhang, Y., Li, B., Xie, L., & Deng, Q. (2019) · Yonsei Medical Journal · doi:10.3349/ymj.2019.60.2.163 · Cited by 21

Expression profile analysis identifies key genes as prognostic markers for metastasis of osteosarcoma

Guan, X., Guan, Z., 季加孚, & Song, C. (2020) · Cancer Cell International · doi:10.1186/s12935-020-01179-x · Cited by 21

Sea cucumber Cucumaria frondosa fucoidan inhibits osteosarcoma adhesion and migration by regulating cytoskeleton remodeling

Zhang, M., Chen, L., Liu, Y., Chen, M., Zhang, S., & Kong, D. (2020) · Oncology Reports · doi:10.3892/or.2020.7614 · Cited by 21

The new horizon of liquid biopsy in sarcoma: the potential utility of circulating tumor nucleic acids

Wei, J., Liu, X., Li, T., Xing, P., Zhang, C., & Yang, J. (2020) · Journal of Cancer · doi:10.7150/jca.42816 · Cited by 21

Identification of 9-Gene Epithelial–Mesenchymal Transition Related Signature of Osteosarcoma by Integrating Multi Cohorts

Zhang, Y., Ziyun, L., Fu, Q., Xingli, W., & Yang, L. (2020) · Technology in Cancer Research & Treatment · doi:10.1177/1533033820980769 · Cited by 21

Histone demethylase KDM5A promotes tumorigenesis of osteosarcoma tumor

Peng, D., Lin, B., Xie, M., Zhang, P., Guo, Q., Li, Q., Gu, Q., Yang, S., & Li, S. (2021) · Cell Death Discovery · doi:10.1038/s41420-020-00396-7 · Cited by 21

The Role of Forkhead Box Family in Bone Metabolism and Diseases

Xu, J., Wang, K., Zhang, Z., Xue, D., Li, W., & Pan, Z. (2022) · Frontiers in Pharmacology · doi:10.3389/fphar.2021.772237 · Cited by 21

Ferroptosis and its implications in bone-related diseases

Wang, Z., Yan, Q., Wang, Z., Hu, Z., Wang, C., Zhang, X., Gao, X., Bai, X., Chen, X., Zhang, L., et al. (2024) · PeerJ · doi:10.7717/peerj.18626 · Cited by 23

Eriodictyol-cisplatin coated nanomedicine synergistically promote osteosarcoma cells ferroptosis and chemosensitivity

Lin, Z., Li, Y., Wu, Z., Liu, Q., Li, X., & Luo, W. (2025) · Journal of Nanobiotechnology · doi:10.1186/s12951-025-03206-3 · Cited by 20

miR-766-3p Targeting BCL9L Suppressed Tumorigenesis, Epithelial-Mesenchymal Transition, and Metastasis Through the β-Catenin Signaling Pathway in Osteosarcoma Cells

Zhang, S., Chen, H., Liu, W., Fang, L., Qian, Z., Kong, R., Zhang, Q., Li, J., & Cao, X. (2020) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2020.594135 · Cited by 20

Identification and Development of a Novel 4-Gene Immune-Related Signature to Predict Osteosarcoma Prognosis

Cao, M., Zhang, J., Xu, H., Lin, Z., Chang, H., Wang, Y., Huang, X., Chen, X., Wang, H., & Song, Y. (2020) · Frontiers in Molecular Biosciences · doi:10.3389/fmolb.2020.608368 · Cited by 20

Classification of Osteosarcoma Based on Immunogenomic Profiling

Wang, X., Wang, L., Xu, W., Wang, X., Ke, D., Lin, J., Lin, W., & Bai, X. (2021) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2021.696878 · Cited by 20

Nuclear receptor modulators inhibit osteosarcoma cell proliferation and tumour growth by regulating the mTOR signaling pathway

Yuan, B., Shi, K., Zha, J., Cai, Y., Gu, Y., Huang, K., Yue, W., Zhai, Q., Ding, N., Ren, W., et al. (2023) · Cell Death and Disease · doi:10.1038/s41419-022-05545-7 · Cited by 21

CPPs-modified chitosan as permeability-enhancing chemotherapeutic combined with gene therapy nanosystem by thermosensitive hydrogel for the treatment of osteosarcoma

Cao, J., Zhu, C., Cao, Z., & Ke, X. (2024) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2024.130915 · Cited by 20

Integrating Radiogenomics and Machine Learning in Musculoskeletal Oncology Care

Kumar, R. R., Sporn, K., Khanna, A., Paladugu, P., Gowda, C., Ngo, A., Jagadeesan, R., Zaman, N., & Tavakkoli, A. (2025) · Diagnostics · doi:10.3390/diagnostics15111377 · Cited by 21

TIMP3 Overexpression Improves the Sensitivity of Osteosarcoma to Cisplatin by Reducing IL-6 Production

Han, X., Mo, H., Liu, X., Li, Y., Du, L., Qiao, H., Fan, Q., Zhao, J., Zhang, S.-H., & Tang, T. (2018) · Frontiers in Genetics · doi:10.3389/fgene.2018.00135 · Cited by 20

SP1-mediated upregulation of lncRNA LMCD1-AS1 functions a ceRNA for miR-106b-5p to facilitate osteosarcoma progression

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