Adipose tissue browning and metabolic health

Brown Adipose Tissue: Function and Physiological Significance

CANNON, B., & NEDERGAARD, J. (2004) · Physiological Reviews · doi:10.1152/physrev.00015.2003 · Cited by 6,433

A PGC1-α-dependent myokine that drives brown-fat-like development of white fat and thermogenesis

Boström, P., Wu, J., Jedrychowski, M. P., Korde, A., Ye, L., Lo, J. C., Rasbach, K. A., Boström, E. A., Choi, J. H., Long, J. Z., et al. (2012) · Nature · doi:10.1038/nature10777 · Cited by 4,810

Obesity induces a phenotypic switch in adipose tissue macrophage polarization

Lumeng, C. N., Bodzin, J. L., & Saltiel, A. R. (2007) · Journal of Clinical Investigation · doi:10.1172/jci29881 · Cited by 4,664

Identification and Importance of Brown Adipose Tissue in Adult Humans

Cypess, A. M., Lehman, S., Williams, G., Tal, I., Rodman, D., Goldfine, A. B., Kuo, F. C., Palmer, E. L., Tseng, Y.-H., Doria, A., et al. (2009) · New England Journal of Medicine · doi:10.1056/nejmoa0810780 · Cited by 4,399

Resveratrol Improves Mitochondrial Function and Protects against Metabolic Disease by Activating SIRT1 and PGC-1α

Lagouge, M., Argmann, C., Gerhart-Hines, Z., Meziane, H., Lerin, C., Daussin, F., Messadeq, N., Milne, J., Lambert, P., Elliott, P., et al. (2006) · Cell · doi:10.1016/j.cell.2006.11.013 · Cited by 4,057

Autophagy regulates lipid metabolism

Singh, R., Kaushik, S., Wang, Y., Xiang, Y., Novak, I., Komatsu, M., Tanaka, K., Cuervo, A. M., & Czaja, M. J. (2009) · Nature · doi:10.1038/nature07976 · Cited by 3,975

A Cold-Inducible Coactivator of Nuclear Receptors Linked to Adaptive Thermogenesis

Puigserver, P., Wu, Z., Park, C. W., Graves, R., Wright, M., & Spiegelman, B. M. (1998) · Cell · doi:10.1016/s0092-8674(00)81410-5 · Cited by 3,864

Cold-Activated Brown Adipose Tissue in Healthy Men

van Marken Lichtenbelt, W. D., Vanhommerig, J. W., Smulders, N. M., Drossaerts, J. M. A. F. L., Kemerink, G. J., Bouvy, N. D., Schrauwen, P., & Teule, G. J. J. (2009) · New England Journal of Medicine · doi:10.1056/nejmoa0808718 · Cited by 3,452

Beige Adipocytes Are a Distinct Type of Thermogenic Fat Cell in Mouse and Human

Wu, J., Boström, P., Sparks, L. M., Li, Y., Choi, J. H., Giang, A.-H., Khandekar, M. J., Virtanen, K. A., Nuutila, P., Schaart, G., et al. (2012) · Cell · doi:10.1016/j.cell.2012.05.016 · Cited by 3,406

AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity

Cantó, C., Gerhart-Hines, Z., Feige, J. N., Lagouge, M., Noriega, L., Milne, J. C., Elliott, P. J., Puigserver, P., & Auwerx, J. (2009) · Nature · doi:10.1038/nature07813 · Cited by 3,300

Nutritional and non-nutritional agents that stimulate white adipose tissue browning

Concha, F., Prado, G., Quezada, J. U. C., Ramı́rez, A., Bravo, N., Flores, C., Herrera, J. J., Lopez, N., Uribe, D., Duarte-Silva, L., et al. (2019) · Reviews in Endocrine and Metabolic Disorders · doi:10.1007/s11154-019-09495-y · Cited by 41

Irisin levels in the progression of diabetes in sedentary women

Duran, İ. D., Gülçelik, N. E., Ünal, M., Topçuoğlu, C., Sezer, S., Tuna, M. M., Berker, D. S., & Güler, S. (2015) · Clinical Biochemistry · doi:10.1016/j.clinbiochem.2015.07.098 · Cited by 41

Fatty Liver/Adipose Tissue Dual‐Targeting Nanoparticles with Heme Oxygenase‐1 Inducer for Amelioration of Obesity, Obesity‐Induced Type 2 Diabetes, and Steatohepatitis

Hong, J., & Kim, Y. (2022) · Advanced Science · doi:10.1002/advs.202203286 · Cited by 42

Polyphenols and intestinal microorganisms: A review of their interactions and effects on human health

Li, Z., Kanwal, R., Yue, X., Li, M., & Xie, A. (2024) · Food Bioscience · doi:10.1016/j.fbio.2024.105220 · Cited by 40

Ambient Temperature and Prevalence of Obesity: A Nationwide Population-Based Study in Korea

Yang, H. K., Han, K., Cho, J., Yoon, K., Cha, B., & Lee, S. (2015) · PLoS ONE · doi:10.1371/journal.pone.0141724 · Cited by 43

Browning and thermogenic programing of adipose tissue

Kiefer, F. W. (2016) · Best Practice & Research Clinical Endocrinology & Metabolism · doi:10.1016/j.beem.2016.09.003 · Cited by 41

Senescent T Cell Induces Brown Adipose Tissue “Whitening” Via Secreting IFN-γ

Pan, X., Yao, K.-L., Yang, Y., Ge, Q., Zhang, R., Gao, P., Ruan, C., & Wu, F. (2021) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2021.637424 · Cited by 41

Peripheral IL-6/STAT3 signaling promotes beiging of white fat

Li, H., Dong, M., Liu, W., Gao, C., Jia, Y., Zhang, X., Xiao, X., Liu, Q., & Lin, H. (2021) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · doi:10.1016/j.bbamcr.2021.119080 · Cited by 40

Anti-Obesity Drug Delivery Systems: Recent Progress and Challenges

Ashour, M. M., Mabrouk, M., Aboelnasr, M. A., Beherei, H. H., Tohamy, K. M., & Das, D. B. (2023) · Pharmaceutics · doi:10.3390/pharmaceutics15112635 · Cited by 42

Modulation of Energy Expenditure by Estrogens and Exercise in Women

Gavin, K. M., Kohrt, W. M., Klemm, D. J., & Melanson, E. L. (2018) · Exercise and Sport Sciences Reviews · doi:10.1249/jes.0000000000000160 · Cited by 45

Berberine is a potential therapeutic agent for metabolic syndrome via brown adipose tissue activation and metabolism regulation.

Hu, X., Zhang, Y., Xue, Y., Zhang, Z., & Wang, J. (2018) · Europe PMC (PubMed Central) · Cited by 38

Towards a Better Understanding of Beige Adipocyte Plasticity

Paulo, E., & Wang, B. (2019) · Cells · doi:10.3390/cells8121552 · Cited by 39

Adiponectin/SIRT1 Axis Induces White Adipose Browning After Vertical Sleeve Gastrectomy of Obese Rats with Type 2 Diabetes

Liu, L., Zhang, T., Hu, J., Ma, R., He, B., Wang, M., & Wang, Y. (2019) · Obesity Surgery · doi:10.1007/s11695-019-04295-4 · Cited by 40

Adipose Tissue Metabolic Function and Dysfunction: Impact of Burn Injury

Kaur, S., Auger, C., & Jeschke, M. G. (2020) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2020.599576 · Cited by 39

Skeletal muscle non-shivering thermogenesis as an attractive strategy to combat obesity

Li, H., Wang, C., Li, L., & Li, L. (2021) · Life Sciences · doi:10.1016/j.lfs.2021.119024 · Cited by 38

Adipocyte‐derived extracellular vesicles in health and diseases: Nano‐packages with vast biological properties

Lay, S. L., Rome, S., Loyer, X., & Nieto, L. (2021) · FASEB BioAdvances · doi:10.1096/fba.2020-00147 · Cited by 42

Intrinsic differences in BRITE adipogenesis of primary adipocytes from two different mouse strains

Li, Y., Bolze, F., Fromme, T., & Klingenspor, M. (2014) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · doi:10.1016/j.bbalip.2014.06.003 · Cited by 38

Diffuse optical spectroscopic imaging of subcutaneous adipose tissue metabolic changes during weight loss

Ganesan, G., Warren, R. V., Leproux, A., Compton, M., Cutler, K., Wittkopp, S., Tran, G., O’Sullivan, T. D., Malik, S., Galassetti, P. R., et al. (2016) · International Journal of Obesity · doi:10.1038/ijo.2016.43 · Cited by 38

UCP1 deficiency increases adipose tissue monounsaturated fatty acid synthesis and trafficking to the liver

Bond, L. M., & Ntambi, J. M. (2017) · Journal of Lipid Research · doi:10.1194/jlr.m078469 · Cited by 38

Lysosomal acid lipase regulates fatty acid channeling in brown adipose tissue to maintain thermogenesis

Duta-Mare, M., Sachdev, V., Leopold, C., Kolb, D., Vujić, N., Korbelius, M., Hofer, D., Xia, W., Huber, K., Auer, M., et al. (2018) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · doi:10.1016/j.bbalip.2018.01.011 · Cited by 37

Perilipin-2 deletion promotes carbohydrate-mediated browning of white adipose tissue at ambient temperature

Libby, A. E., Bales, E. S., Monks, J., Orlicky, D. J., & McManaman, J. L. (2018) · Journal of Lipid Research · doi:10.1194/jlr.m086249 · Cited by 38

Aerobic exercise training prevents obesity and insulin resistance independent of the renin angiotensin system modulation in the subcutaneous white adipose tissue

Américo, A. L. V., Muller, C. R., Vecchiatto, B., Martucci, L. F., Fonseca‐Alaniz, M. H., & Evangelista, F. S. (2019) · PLoS ONE · doi:10.1371/journal.pone.0215896 · Cited by 38

Tbx15 is required for adipocyte browning induced by adrenergic signaling pathway

Sun, W., Zhao, X., Wang, Z., Chu, Y., Mao, L., Lin, S., Gao, X., Yu-na, S., Hui, X. H., Jia, S., et al. (2019) · Molecular Metabolism · doi:10.1016/j.molmet.2019.07.004 · Cited by 37

Natural Bioactive Compounds as Potential Browning Agents in White Adipose Tissue

Choi, Y., & Yu, L. (2021) · Pharmaceutical Research · doi:10.1007/s11095-021-03027-7 · Cited by 39

Pancreatic cancer: branched-chain amino acids as putative key metabolic regulators?

Rossmeislová, L., Gojda, J., & Smolková, K. (2021) · Cancer and Metastasis Reviews · doi:10.1007/s10555-021-10016-0 · Cited by 38

Withania somnifera Extract Enhances Energy Expenditure via Improving Mitochondrial Function in Adipose Tissue and Skeletal Muscle

Lee, D.-H., Ahn, J., Jang, Y. J., Seo, H., Ha, T. Y., Kim, M. J., Huh, Y. H., & Jung, C. H. (2020) · Nutrients · doi:10.3390/nu12020431 · Cited by 42

Adipose tissue engineering

Louis, F., & Matsusaki, M. (2020) · Elsevier eBooks · doi:10.1016/b978-0-08-102906-0.00008-8 · Cited by 37

Metformin alleviates hyperuricaemia-induced serum FFA elevation and insulin resistance by inhibiting adipocyte hypertrophy and reversing suppressed white adipose tissue beiging

Su, M., Sun, L., Li, W., Liu, H., Liu, Y., Wei, Y., Yuan, Y., Zheng, L., Yin, S., Dai, C., et al. (2020) · Clinical Science · doi:10.1042/cs20200580 · Cited by 37

Adipose Tissue Immunometabolism and Apoptotic Cell Clearance

Rőszer, T. (2021) · Cells · doi:10.3390/cells10092288 · Cited by 41

Reduced hepatic bradykinin degradation accounts for cold-induced BAT thermogenesis and WAT browning in male mice

Xiao, F., Jiang, H., Li, Z., Jiang, X., Chen, S., Niu, Y., Yin, H., Shu, Y., Peng, B., Lu, W., et al. (2023) · Nature Communications · doi:10.1038/s41467-023-38141-0 · Cited by 36

Nanomedicine for obesity treatment

Zhang, Y., Yu, J., Qiang, L., & Gu, Z. (2018) · Science China Life Sciences · doi:10.1007/s11427-017-9257-1 · Cited by 36

Brown Adipose Tissue—A Therapeutic Target in Obesity?

Trayhurn, P. (2018) · Frontiers in Physiology · doi:10.3389/fphys.2018.01672 · Cited by 37

Oxyresveratrol Increases Energy Expenditure through Foxo3a-Mediated Ucp1 Induction in High-Fat-Diet-Induced Obese Mice

Choi, J. H., Song, N., Lee, A. R., Lee, D. H., Seo, M.-J., Kim, S., Chang, S., Yang, D. K., Hwang, Y.-J., Hwang, K., et al. (2018) · International Journal of Molecular Sciences · doi:10.3390/ijms20010026 · Cited by 36

Association of uncoupling protein (Ucp) gene polymorphisms with cardiometabolic diseases

Pravednikova, A. E., Shevchenko, S. Y., Kerchev, V. V., Схиртладзе, М. Р., Николаевна, Л. С., Kachaev, Z. M., Egorov, A. D., & Shidlovskii, Y. V. (2020) · Molecular Medicine · doi:10.1186/s10020-020-00180-4 · Cited by 37

Adipocyte-targeted delivery of rosiglitazone with localized photothermal therapy for the treatment of diet-induced obesity in mice

Zhang, Y., Luo, M., Jia, Y., Gao, T., Deng, L., Gong, T., Zhang, Z., Cao, X., & Fu, Y. S. (2024) · Acta Biomaterialia · doi:10.1016/j.actbio.2024.04.029 · Cited by 35

Metabolaging: a new geroscience perspective linking aging pathologies and metabolic dysfunction

Khalaf, F., Barayan, D., Saldanha, S., & Jeschke, M. G. (2025) · Metabolism · doi:10.1016/j.metabol.2025.156158 · Cited by 43

FGF21, energy expenditure and weight loss – How much brown fat do you need?

Straub, L. G., & Wolfrum, C. (2015) · Molecular Metabolism · doi:10.1016/j.molmet.2015.06.008 · Cited by 35

Classification of Therapeutic and Experimental Drugs for Brown Adipose Tissue Activation: Potential Treatment Strategies for Diabetes and Obesity

Mukherjee, J., Baranwal, A., & Schade, K. N. (2016) · Current Diabetes Reviews · doi:10.2174/1573399812666160517115450 · Cited by 37

The emerging roles of lactate as a redox substrate and signaling molecule in adipose tissues

Carrière, A., Lagarde, D., Jeanson, Y., Portais, J., Galinier, A., Ader, I., & Casteilla, L. (2020) · Journal of Physiology and Biochemistry · doi:10.1007/s13105-019-00723-2 · Cited by 35

Dietary apple polyphenols promote fat browning in high‐fat diet‐induced obese mice through activation of adenosine monophosphate‐activated protein kinase α

Zou, T., Wang, B., Li, S., Liu, Y., & You, J. (2020) · Journal of the Science of Food and Agriculture · doi:10.1002/jsfa.10248 · Cited by 35

Ginsenoside Rd Ameliorates High Fat Diet‐Induced Obesity by Enhancing Adaptive Thermogenesis in a cAMP‐Dependent Manner

Yao, L., Han, Z., Zhao, G., Xiao, Y., Zhou, X., Dai, R., Han, M., Wang, Z., Xin, R., & Wang, S. (2020) · Obesity · doi:10.1002/oby.22761 · Cited by 35

Nobiletin activates thermogenesis of brown and white adipose tissue in high‐fat diet‐fed C57BL/6 mice by shaping the gut microbiota

Kou, G., Li, P., Hu, Y., Chen, H., Amoah, A. N., Traore, S. S., Cui, Z., & Lyu, Q. (2021) · The FASEB Journal · doi:10.1096/fj.202002197r · Cited by 34

TFEB deficiency attenuates mitochondrial degradation upon brown adipose tissue whitening at thermoneutrality

Sass, F., Schlein, C., Jaeckstein, M. Y., Pertzborn, P., Schweizer, M., Schinke, T., Ballabio, A., Scheja, L., Heeren, J., & Fischer, A. W. (2021) · Molecular Metabolism · doi:10.1016/j.molmet.2021.101173 · Cited by 34

RNA-Seq Reveals Function of Bta-miR-149-5p in the Regulation of Bovine Adipocyte Differentiation

Guo, H., Khan, R., Raza, S. H. A., Suhail, S. M., Khan, H., Khan, S. B., El-Aziz, A. H. A., & Zan, L. (2021) · Animals · doi:10.3390/ani11051207 · Cited by 35

A direct tissue-grafting approach to increasing endogenous brown fat

Blumenfeld, N. R., Kang, H. J., Fenzl, A., Song, Z., Chung, J., Singh, R., Johnson, R., Karakeçili, A. G., FERANIL, J. B., Rossen, N. S., et al. (2018) · Scientific Reports · doi:10.1038/s41598-018-25866-y · Cited by 35

Salvianolic acid B protects against pulmonary fibrosis by attenuating stimulating protein 1‐mediated macrophage and alveolar type 2 cell senescence

Li, Y., Chen, R., Wu, J., Xue, X., Liu, T., Peng, G., Wu, R., Wang, L., Jia, K., Cai, Y., et al. (2023) · Phytotherapy Research · doi:10.1002/ptr.8070 · Cited by 34

Eosinophils in Fat: Pink Is the New Brown

Lee, S. D., & Tontonoz, P. (2014) · Cell · doi:10.1016/j.cell.2014.05.025 · Cited by 34

Beneficial Effects of Evogliptin, a Novel Dipeptidyl Peptidase 4 Inhibitor, on Adiposity with Increased Ppargc1a in White Adipose Tissue in Obese Mice

Chae, Y., Kim, T., Kim, M. K., Shin, C.-Y., Jung, I.-H., Sohn, Y. S., & Son, M.-H. (2015) · PLoS ONE · doi:10.1371/journal.pone.0144064 · Cited by 34

Feast and famine: Adipose tissue adaptations for healthy aging

Lettieri‐Barbato, D., & Aquilano, K. (2016) · Ageing Research Reviews · doi:10.1016/j.arr.2016.05.007 · Cited by 35

An ERβ agonist induces browning of subcutaneous abdominal fat pad in obese female mice

Miao, Y., Su, W., Dai, Y.-B., Wu, W.-F., Huang, B., Barros, R. P. A., Nguyen, H., Maneix, L., Guan, Y., Warner, M. N., et al. (2016) · Scientific Reports · doi:10.1038/srep38579 · Cited by 34

Effects of sildenafil treatment on thermogenesis and glucose homeostasis in diet-induced obese mice

Johann, K., Reis, M. C., Harder, L., Herrmann, B., Gachkar, S., Mittag, J., & Oelkrug, R. (2018) · Nutrition and Diabetes · doi:10.1038/s41387-018-0026-0 · Cited by 34

Deletion of iRhom2 protects against diet-induced obesity by increasing thermogenesis

Badenes, M., Amin, A., González‐García, I., Félix, I., Burbridge, E., Cavadas, M. A. S., Ortega, F. J., de Carvalho, É., Faísca, P., Carobbio, S., et al. (2019) · Molecular Metabolism · doi:10.1016/j.molmet.2019.10.006 · Cited by 31

Regulation of thermogenic adipocytes during fasting and cold

Reinisch, I., Schreiber, R., & Prokesch, A. (2020) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2020.110869 · Cited by 36

Mulberry leaf activates brown adipose tissue and induces browning of inguinal white adipose tissue in type 2 diabetic rats through regulating AMP-activated protein kinase signalling pathway

Cheng, L., Wang, J., An, Y., Dai, H., Duan, Y., Shi, L., Lv, Y., Li, H., Wang, C., Du, H., et al. (2021) · British Journal Of Nutrition · doi:10.1017/s0007114521001537 · Cited by 34

Empagliflozin Induces White Adipocyte Browning and Modulates Mitochondrial Dynamics in KK Cg-Ay/J Mice and Mouse Adipocytes

Xu, L., Xu, C., Liu, X., Li, X., Li, T., Yu, X., Xue, M., Yang, J., Kosmas, C. E., Moris, D., et al. (2021) · Frontiers in Physiology · doi:10.3389/fphys.2021.745058 · Cited by 34

Extending the translational potential of targeting NO/ cGMP ‐regulated pathways in the CVS

Papapetropoulos, A., Hobbs, A. J., & Topouzis, S. (2014) · British Journal of Pharmacology · doi:10.1111/bph.12980 · Cited by 35

Free fatty acids and IL-6 induce adipocyte galectin-3 which is increased in white and brown adipose tissues of obese mice

Krautbauer, S., Eisinger, K., Hader, Y., & Buechler, C. (2014) · Cytokine · doi:10.1016/j.cyto.2014.06.016 · Cited by 36

Characterization of the central neural projections to brown, white, and beige adipose tissue

Wiedmann, N. M., Stefanidis, A., & Oldfield, B. J. (2017) · The FASEB Journal · doi:10.1096/fj.201700433r · Cited by 33

Divergent responses to thermogenic stimuli in BAT and subcutaneous adipose tissue from interleukin 18 and interleukin 18 receptor 1-deficient mice

Pazos, P., Lima, L., Tovar, S., González-Touceda, D., Diéguez, C., & García, M. C. (2015) · Scientific Reports · doi:10.1038/srep17977 · Cited by 33

Neohesperidin Dihydrochalcone and Neohesperidin Dihydrochalcone-O-Glycoside Attenuate Subcutaneous Fat and Lipid Accumulation by Regulating PI3K/AKT/mTOR Pathway In Vivo and In Vitro

Kwon, M., Kim, Y., Lee, J., Manthey, J. A., Kim, Y., & Kim, Y. (2022) · Nutrients · doi:10.3390/nu14051087 · Cited by 35

Mechanisms of bariatric surgery for weight loss and diabetes remission

Yin, M., Wang, Y., Han, M., Liang, R., Li, S., Wang, G., & Gang, X. (2023) · Journal of Diabetes · doi:10.1111/1753-0407.13443 · Cited by 36

Intrinsic Properties of Brown and White Adipocytes Have Differential Effects on Macrophage Inflammatory Responses

Dowal, L. M., Parameswaran, P., Phat, S., Akella, S., Majumdar, I. D., Ranjan, J., Shah, C., Mogre, S., Guntur, K., Thapa, K., et al. (2017) · Mediators of Inflammation · doi:10.1155/2017/9067049 · Cited by 36

Brown Adipose Tissue: A Human Perspective

Boon, M. R., & Lichtenbelt, W. D. V. M. (2015) · Handbook of experimental pharmacology · doi:10.1007/164_2015_11 · Cited by 35

Caloric restriction for the immunometabolic control of human health

Procaccini, C., de Candia, P., Russo, C., Rosa, G. D., Lepore, M. T., Colamatteo, A., & Matarese, G. (2023) · Cardiovascular Research · doi:10.1093/cvr/cvad035 · Cited by 35

Aromatase Controls Sjögren Syndrome–Like Lesions through Monocyte Chemotactic Protein-1 in Target Organ and Adipose Tissue–Associated Macrophages

Iwasa, A., Arakaki, R., Honma, N., Ushio, A., Yamada, A., Kondo, T., Kurosawa, E., Kujiraoka, S., Tsunematsu, T., Kudo, Y., et al. (2014) · American Journal Of Pathology · doi:10.1016/j.ajpath.2014.09.006 · Cited by 32

Of mice and men: novel insights regarding constitutive and recruitable brown adipocytes

Townsend, K. L., & Tseng, Y.-H. (2015) · International Journal of Obesity Supplements · doi:10.1038/ijosup.2015.5 · Cited by 32

Effects of Bariatric Surgery on Change of Brown Adipocyte Tissue and Energy Metabolism in Obese Mice

Chen, Y., Yang, J., Nie, X., Song, Z., & Gu, Y. (2017) · Obesity Surgery · doi:10.1007/s11695-017-2899-8 · Cited by 32

Phyllodulcin, a Natural Sweetener, Regulates Obesity-Related Metabolic Changes and Fat Browning-Related Genes of Subcutaneous White Adipose Tissue in High-Fat Diet-Induced Obese Mice

Kim, E., Lim, S.-M., Kim, M., Yoo, S., & Kim, Y. (2017) · Nutrients · doi:10.3390/nu9101049 · Cited by 33

A pivotal role of AMPK signaling in medicarpin‐mediated formation of brown and beige

Imran, K. M., Yoon, D., & Kim, Y. (2017) · BioFactors · doi:10.1002/biof.1392 · Cited by 31

ChREBP-β regulates thermogenesis in brown adipose tissue

Wei, C., Ma, X., Su, K., Qi, S., Zhu, Y., Lin, J., Wang, C., Yang, R., Chen, X., Wang, W., et al. (2020) · Journal of Endocrinology · doi:10.1530/joe-19-0498 · Cited by 33

The Potential Role of Exosomes in Child and Adolescent Obesity

Maligianni, I., Yapijakis, C., Bacopoulou, F., & Chrousos, G. P. (2021) · Children · doi:10.3390/children8030196 · Cited by 32

FNIP1 regulates adipocyte browning and systemic glucose homeostasis in mice by shaping intracellular calcium dynamics

Yin, Y., Xu, D., Mao, Y., Xiao, L., Sun, Z., Liu, J., Zhou, D., Xu, Z., Liu, L., Fu, T., et al. (2022) · The Journal of Experimental Medicine · doi:10.1084/jem.20212491 · Cited by 34

Metabolic Response of Visceral White Adipose Tissue of Obese Mice Exposed for 5 Days to Human Room Temperature Compared to Mouse Thermoneutrality

van der Stelt, I., Hoevenaars, F. P. M., Široká, J., de Ronde, L., Friedecký, D., Keijer, J., & van Schothorst, E. M. (2017) · Frontiers in Physiology · doi:10.3389/fphys.2017.00179 · Cited by 32

Theaflavin-3,3′-digallate, a black tea polyphenol, stimulates lipolysis associated with the induction of mitochondrial uncoupling proteins and AMPK–FoxO3A–MnSOD pathway in 3T3-L1 adipocytes

Ko, H.-J., Lo, C., Wang, B.-J., Chiou, R. Y. ‐., & Lin, S. (2015) · Journal of Functional Foods · doi:10.1016/j.jff.2015.05.033 · Cited by 32

PRMT4 Facilitates White Adipose Tissue Browning and Thermogenesis by Methylating PPARγ

Zhong, Y., Wang, Y., Li, X., Qin, H., Yan, S. W., Rao, C., Fan, D., Liu, D., Deng, F., Miao, Y., et al. (2023) · Diabetes · doi:10.2337/db22-1016 · Cited by 36

Heart Failure With Preserved Ejection Fraction and Adipose Tissue: A Story of Two Tales

Oh, A., Okazaki, R. A., Sam, F., & Valero‐Muñoz, M. (2019) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2019.00110 · Cited by 32

Polyphenol-rich green tea extract induces thermogenesis in mice by a mechanism dependent on adiponectin signaling

Bolin, A. P., Filho, C. P. B. S., Marinovic, M. P., Rodrigues, A. C., & Otton, R. (2019) · The Journal of Nutritional Biochemistry · doi:10.1016/j.jnutbio.2019.108322 · Cited by 31

Protective Effects of Polyphenols Present in Mediterranean Diet on Endothelial Dysfunction

Stromsnes, K., Mas‐Bargues, C., Gambini, J., & Gimeno-Mallench, L. (2020) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2020/2097096 · Cited by 32

Aging and Immunometabolic Adaptations to Thermogenesis

Lettieri‐Barbato, D., & Aquilano, K. (2020) · Ageing Research Reviews · doi:10.1016/j.arr.2020.101143 · Cited by 33

miRNA-22 deletion limits white adipose expansion and activates brown fat to attenuate high-fat diet-induced fat mass accumulation

Lima, V. M., Liu, J., Brandão, B. B., Lino, C. A., Balbino-Silva, C., Ribeiro, M. A. C., Oliveira, T. E., Real, C. C., Faria, D. D. P., Cederquist, C., et al. (2021) · Metabolism · doi:10.1016/j.metabol.2021.154723 · Cited by 32

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