Adipose tissue browning and metabolic health

Brown Adipose Tissue: Function and Physiological Significance

CANNON, B., & NEDERGAARD, J. (2004) · Physiological Reviews · doi:10.1152/physrev.00015.2003 · Cited by 6,433

A PGC1-α-dependent myokine that drives brown-fat-like development of white fat and thermogenesis

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Obesity induces a phenotypic switch in adipose tissue macrophage polarization

Lumeng, C. N., Bodzin, J. L., & Saltiel, A. R. (2007) · Journal of Clinical Investigation · doi:10.1172/jci29881 · Cited by 4,664

Identification and Importance of Brown Adipose Tissue in Adult Humans

Cypess, A. M., Lehman, S., Williams, G., Tal, I., Rodman, D., Goldfine, A. B., Kuo, F. C., Palmer, E. L., Tseng, Y.-H., Doria, A., et al. (2009) · New England Journal of Medicine · doi:10.1056/nejmoa0810780 · Cited by 4,399

Resveratrol Improves Mitochondrial Function and Protects against Metabolic Disease by Activating SIRT1 and PGC-1α

Lagouge, M., Argmann, C., Gerhart-Hines, Z., Meziane, H., Lerin, C., Daussin, F., Messadeq, N., Milne, J., Lambert, P., Elliott, P., et al. (2006) · Cell · doi:10.1016/j.cell.2006.11.013 · Cited by 4,057

Autophagy regulates lipid metabolism

Singh, R., Kaushik, S., Wang, Y., Xiang, Y., Novak, I., Komatsu, M., Tanaka, K., Cuervo, A. M., & Czaja, M. J. (2009) · Nature · doi:10.1038/nature07976 · Cited by 3,975

A Cold-Inducible Coactivator of Nuclear Receptors Linked to Adaptive Thermogenesis

Puigserver, P., Wu, Z., Park, C. W., Graves, R., Wright, M., & Spiegelman, B. M. (1998) · Cell · doi:10.1016/s0092-8674(00)81410-5 · Cited by 3,864

Cold-Activated Brown Adipose Tissue in Healthy Men

van Marken Lichtenbelt, W. D., Vanhommerig, J. W., Smulders, N. M., Drossaerts, J. M. A. F. L., Kemerink, G. J., Bouvy, N. D., Schrauwen, P., & Teule, G. J. J. (2009) · New England Journal of Medicine · doi:10.1056/nejmoa0808718 · Cited by 3,452

Beige Adipocytes Are a Distinct Type of Thermogenic Fat Cell in Mouse and Human

Wu, J., Boström, P., Sparks, L. M., Li, Y., Choi, J. H., Giang, A.-H., Khandekar, M. J., Virtanen, K. A., Nuutila, P., Schaart, G., et al. (2012) · Cell · doi:10.1016/j.cell.2012.05.016 · Cited by 3,406

AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity

Cantó, C., Gerhart-Hines, Z., Feige, J. N., Lagouge, M., Noriega, L., Milne, J. C., Elliott, P. J., Puigserver, P., & Auwerx, J. (2009) · Nature · doi:10.1038/nature07813 · Cited by 3,300

Cellular models for the evaluation of the antiobesity effect of selected phytochemicals from food and herbs

Tung, Y., Hsieh, P., Pan, M., & Ho, C. (2016) · Journal of Food and Drug Analysis · doi:10.1016/j.jfda.2016.10.018 · Cited by 64

Fndc5 loss‐of‐function attenuates exercise‐induced browning of white adipose tissue in mice

Xiong, Y., Wu, Z., Zhang, B., Wang, C., Mao, F., Liu, X., Hu, K., Sun, X., Jin, W. L., & Kuang, S. (2019) · The FASEB Journal · doi:10.1096/fj.201801754rr · Cited by 64

The Presence of Active Brown Adipose Tissue Determines Cold-Induced Energy Expenditure and Oxylipin Profiles in Humans

Kulterer, O. C., Niederstaetter, L., Herz, C. T., Haug, A. R., Bileck, A., Pils, D., Kautzky‐Willer, A., Gerner, C., & Kiefer, F. W. (2020) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/clinem/dgaa183 · Cited by 64

Polyphenols and their anti-obesity role mediated by the gut microbiota: a comprehensive review

Duarte-Silva, L., Gasaly, N., Poblete-Aro, C., Uribe, D., Echeverría, F., Gotteland, M., & García‐Díaz, D. F. (2021) · Reviews in Endocrine and Metabolic Disorders · doi:10.1007/s11154-020-09622-0 · Cited by 67

Lactate induces FGF21 expression in adipocytes through a p38-MAPK pathway

Jeanson, Y., Ribas‐Aulinas, F., Galinier, A., Arnaud, E., Ducos, M., André, M., Chenouard, V., Villarroya, F., Casteilla, L., & Carrière, A. (2016) · Biochemical Journal · doi:10.1042/bj20150808 · Cited by 59

The use of infrared thermography in the measurement and characterization of brown adipose tissue activation

Law, J., Chalmers, J., Morris, D. E., Robinson, L., Budge, H., & Symonds, M. E. (2017) · Temperature · doi:10.1080/23328940.2017.1397085 · Cited by 65

The Apolipoprotein M/S1P Axis Controls Triglyceride Metabolism and Brown Fat Activity

Christoffersen, C., Federspiel, C. K., Borup, A., Christensen, P. M., Madsen, A. N., Heine, M., Nielsen, C. H., Kjær, A., Holst, B., Heeren, J., et al. (2018) · Cell Reports · doi:10.1016/j.celrep.2017.12.029 · Cited by 63

Sympathetic inputs regulate adaptive thermogenesis in brown adipose tissue through cAMP-Salt inducible kinase axis

Paulo, E., Wu, D., Wang, Y., Zhang, Y., Wu, Y., Swaney, D. L., Soucheray, M., Jimenez-Morales, D., Chawla, A., Krogan, N. J., et al. (2018) · Scientific Reports · doi:10.1038/s41598-018-29333-6 · Cited by 59

Hepatic PTEN deficiency improves muscle insulin sensitivity and decreases adiposity in mice

Peyrou, M., Bourgoin, L., Poher, A.-L., Altirriba, J., Maeder, C., Caillon, A., Fournier, M., Montet, X., Rohner‐Jeanrenaud, F., & Foti, M. (2014) · Journal of Hepatology · doi:10.1016/j.jhep.2014.09.012 · Cited by 59

Uncovering the Role of p38 Family Members in Adipose Tissue Physiology

Leiva, M., Matesanz, N., Pulgarín-Alfaro, M., Nikolić, I., & Sabio, G. (2020) · Frontiers in Endocrinology · doi:10.3389/fendo.2020.572089 · Cited by 62

Nutritional approaches for managing obesity-associated metabolic diseases

Botchlett, R. E., Woo, S., Liu, M., Pei, Y., Guo, X., Li, H., & Wu, C. (2017) · Journal of Endocrinology · doi:10.1530/joe-16-0580 · Cited by 65

Involvement of calcium channels in the regulation of adipogenesis

Zhai, M., Yang, D., Yi, W., & Sun, W. (2020) · Adipocyte · doi:10.1080/21623945.2020.1738792 · Cited by 59

Present and Future: Crosstalks Between Polycystic Ovary Syndrome and Gut Metabolites Relating to Gut Microbiota

Zhang, M., Hu, R., Huang, Y., Zhou, F., Li, F., Liu, Z., Geng, Y., Dong, H., Ma, W., Song, K., et al. (2022) · Frontiers in Endocrinology · doi:10.3389/fendo.2022.933110 · Cited by 58

Postbiotics against Obesity: Perception and Overview Based on Pre-Clinical and Clinical Studies

Park, S., Sharma, A., & Lee, H. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24076414 · Cited by 63

Cannabidiol promotes browning in 3T3-L1 adipocytes

Parray, H. A., & Yun, J. W. (2016) · Molecular and Cellular Biochemistry · doi:10.1007/s11010-016-2702-5 · Cited by 62

Lipopolysaccharide-binding protein is a negative regulator of adipose tissue browning in mice and humans

Gavaldà‐Navarro, A., Moreno‐Navarrete, J. M., Quesada‐López, T., Cairó, M., Giralt, M., Fernández‐Real, J. M., & Villarroya, F. (2016) · Diabetologia · doi:10.1007/s00125-016-4028-y · Cited by 56

Mitochondria-associated ER membranes in glucose homeostasis and insulin resistance

Townsend, L. K., Brunetta, H. S., & Mori, M. A. (2020) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00271.2020 · Cited by 57

The Eicosanoids, Redox-Regulated Lipid Mediators in Immunometabolic Disorders

de Araújo, A. C. J., Wheelock, C. E., & Haeggström, J. Z. (2017) · Antioxidants and Redox Signaling · doi:10.1089/ars.2017.7332 · Cited by 58

Retinoic Acid Increases Fatty Acid Oxidation and Irisin Expression in Skeletal Muscle Cells and Impacts Irisin In Vivo

Amengual, J., García‐Carrizo, F., Arreguín, A., Mušinović, H., Granados, N., Palou, A., Bonet, M. L., & Ribot, J. (2018) · Cellular Physiology and Biochemistry · doi:10.1159/000488422 · Cited by 56

The Importance of Biophysical and Biochemical Stimuli in Dynamic Skeletal Muscle Models

Maleiner, B., Tomasch, J., Heher, P., Oliver Spadiut, A., Rünzler, D., & Fuchs, C. (2018) · Frontiers in Physiology · doi:10.3389/fphys.2018.01130 · Cited by 60

Role of VEGFs in metabolic disorders

Somma, M. D., Vliora, M., Grillo, E., Castro, B., Dakou, E., Schaafsma, W., Vanparijs, J., Corsini, M., Ravelli, C., Sakellariou, E., et al. (2019) · Angiogenesis · doi:10.1007/s10456-019-09700-1 · Cited by 55

Insights into brown adipose tissue evolution and function from non-model organisms

Jastroch, M., Oelkrug, R., & Keipert, S. (2018) · Journal of Experimental Biology · doi:10.1242/jeb.169425 · Cited by 55

TGF-β receptor 1 regulates progenitors that promote browning of white fat

Wankhade, U. D., Lee, J.-H., Dagur, P. K., Yadav, H., Shen, M., Chen, W., Kulkarni, A. B., McCoy, J. P., Finkel, T., Cypess, A. M., et al. (2018) · Molecular Metabolism · doi:10.1016/j.molmet.2018.07.008 · Cited by 58

Depot-specific UCP1 expression in human white adipose tissue and its association with obesity-related markers

Lim, J., Park, H. S., Kim, J., Jang, Y. J., Kim, J.-H., Lee, Y., & Heo, Y. (2020) · International Journal of Obesity · doi:10.1038/s41366-020-0528-4 · Cited by 56

Follistatin targets distinct pathways to promote Brown adipocyte characteristics in Brown and white adipose tissues

Singh, R., Braga, M., Reddy, S. T., Lee, S.-J., Parveen, M., Grijalva, V., Vergnes, L., & Pervin, S. (2017) · Endocrinology · doi:10.1210/en.2016-1607 · Cited by 54

Intrinsic expression of viperin regulates thermogenesis in adipose tissues

Eom, J., Kim, J. J., Yoon, S. G., Jeong, H., Son, S., Lee, J.-B., Yoo, J., Seo, H. J., Cho, Y., Kim, K. S., et al. (2019) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1904480116 · Cited by 55

Basal and cold-induced fatty acid uptake of human brown adipose tissue is impaired in obesity

Saari, T., Raiko, J. R. H., U-Din, M., Niemi, T. S., Taittonen, M. T., Laine, J., Savisto, N., Haaparanta‐Solin, M., Nuutila, P., & Virtanen, K. A. (2020) · Scientific Reports · doi:10.1038/s41598-020-71197-2 · Cited by 59

Role of RAGE in obesity-induced adipose tissue inflammation and insulin resistance

Feng, Z., Du, Z., Shu, X. Y., Zhu, L., Wu, J., Gao, Q., Wang, L., Chen, N., Li, Y., Luo, M., et al. (2021) · Cell Death Discovery · doi:10.1038/s41420-021-00711-w · Cited by 56

Browning Epicardial Adipose Tissue: Friend or Foe?

Doukbi, E., Soghomonian, A., Sengenès, C., Ahmed, S., Ancel, P., Dutour, A., & Gaborit, B. (2022) · Cells · doi:10.3390/cells11060991 · Cited by 60

Human White and Brite Adipogenesis is Supported by MSCA1 and is Impaired by Immune Cells

Estève, D., Boulet, N., Volat, F., Zakaroff‐Girard, A., Ledoux, S., Coupaye, M., Decaunes, P., Belles, C., Gaits‐Iacovoni, F., Iacovoni, J. S., et al. (2014) · Stem Cells · doi:10.1002/stem.1916 · Cited by 62

Does IRISIN Have a BRITE Future as a Therapeutic Agent in Humans?

Irving, B. A., Still, C. D., & Argyropoulos, G. A. (2014) · Current Obesity Reports · doi:10.1007/s13679-014-0091-1 · Cited by 56

Hydrogen Sulfide in the Adipose Tissue—Physiology, Pathology and a Target for Pharmacotherapy

Bełtowski, J., & Jamróz-Wiśniewska, A. (2016) · Molecules · doi:10.3390/molecules22010063 · Cited by 54

Adipocytes in hematopoiesis and acute leukemia: friends, enemies, or innocent bystanders?

Zinngrebe, J., Debatin, K., & Fischer‐Posovszky, P. (2020) · Leukemia · doi:10.1038/s41375-020-0886-x · Cited by 64

A-FABP in Metabolic Diseases and the Therapeutic Implications: An Update

Li, H., Wu, X., Xu, A., & Hoo, R. L. C. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22179386 · Cited by 57

Redox regulation of endothelial cell fate

Song, P., & Zou, M. (2014) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-014-1598-z · Cited by 53

Diet‐induced obesity and insulin resistance are associated with brown fat degeneration in SIRT 1‐deficient mice

Xu, F. L., Zheng, X., Lin, B., Liang, H., Cai, M., Cao, H., Ye, J., & Weng, J. (2016) · Obesity · doi:10.1002/oby.21393 · Cited by 56

Magnolol promotes thermogenesis and attenuates oxidative stress in 3T3-L1 adipocytes

Parray, H. A., Lone, J. B., Park, J. P., Choi, J. W., & Yun, J. W. (2018) · Nutrition · doi:10.1016/j.nut.2018.01.017 · Cited by 54

EGCG stimulates the recruitment of brite adipocytes, suppresses adipogenesis and counteracts TNF-α-triggered insulin resistance in adipocytes

Mi, Y., Liu, X., Tian, H., Liu, H., Li, J., Qi, G., & Liu, X. (2018) · Food & Function · doi:10.1039/c8fo00167g · Cited by 53

The therapeutic effect of interleukin-22 in high androgen-induced polycystic ovary syndrome

Qi, X., Yun, C., Liao, B., Qiao, J., & Pang, Y. (2020) · Journal of Endocrinology · doi:10.1530/joe-19-0589 · Cited by 52

Adrenomedullin 2 Enhances Beiging in White Adipose Tissue Directly in an Adipocyte-autonomous Manner and Indirectly through Activation of M2 Macrophages

Lv, Y., Zhang, S., Liang, X., Zhang, H., Zhi, X., Liu, B., Xu, M., Jiang, C., Shang, J., & Wang, X. (2016) · Journal of Biological Chemistry · doi:10.1074/jbc.m116.735563 · Cited by 53

Regulation of immunometabolism in adipose tissue

Kumari, M., Heeren, J., & Scheja, L. (2017) · Seminars in Immunopathology · doi:10.1007/s00281-017-0668-3 · Cited by 53

Phytol stimulates the browning of white adipocytes through the activation of AMP-activated protein kinase (AMPK) α in mice fed high-fat diet

Zhang, F., Ai, W., Hu, X., Meng, Y., Yuan, C., Su, H., Wang, L., Zhu, X., Gao, P., Shu, G., et al. (2018) · Food & Function · doi:10.1039/c7fo01817g · Cited by 52

Beige Fat Maintenance; Toward a Sustained Metabolic Health

Rabiee, A. (2020) · Frontiers in Endocrinology · doi:10.3389/fendo.2020.00634 · Cited by 53

Energy Metabolism and Aging

Bartke, A., Brannan, S., Hascup, E. R., Hascup, K. N., & Darcy, J. (2020) · The World Journal of Men s Health · doi:10.5534/wjmh.200112 · Cited by 52

New approaches targeting brown adipose tissue transplantation as a therapy in obesity

Soler‐Vázquez, M. C., Mera, P., Zagmutt, S., Serra, D., & Herrero, L. (2018) · Biochemical Pharmacology · doi:10.1016/j.bcp.2018.07.022 · Cited by 55

Transdermal Drug Delivery Systems and Their Use in Obesity Treatment

Li, Z., Fang, X., & Yu, D. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms222312754 · Cited by 53

Natural bioactive constituents from herbs and nutraceuticals promote browning of white adipose tissue

Ma, P.-Y., Li, X., Wang, Y., Lang, D.-Q., Liu, L., Yi, Y., Liu, Q., & Shen, C. (2022) · Pharmacological Research · doi:10.1016/j.phrs.2022.106175 · Cited by 52

Not all fats are created equal: adipose vs. ectopic fat, implication in cardiometabolic diseases

Gaggini, M., Saponaro, C., & Gastaldelli, A. (2015) · Hormone Molecular Biology and Clinical Investigation · doi:10.1515/hmbci-2015-0006 · Cited by 51

Unlock the Thermogenic Potential of Adipose Tissue: Pharmacological Modulation and Implications for Treatment of Diabetes and Obesity

Peng, X., Gennemark, P., O’Mahony, G., & Bartesaghi, S. (2015) · Frontiers in Endocrinology · doi:10.3389/fendo.2015.00174 · Cited by 49

Attenuation of diet-induced obesity and induction of white fat browning with a chemical inhibitor of histone deacetylases

Ferrari, A., Fiorino, E., Longo, R., Barilla, S., Mitro, N., Cermenati, G., Giudici, M., Caruso, D., Mai, A., Guerrini, U., et al. (2016) · International Journal of Obesity · doi:10.1038/ijo.2016.191 · Cited by 53

Adipose tissue plasticity and the pleiotropic roles of BMP signaling

Qian, S., Tang, Y., & Tang, Q. (2021) · Journal of Biological Chemistry · doi:10.1016/j.jbc.2021.100678 · Cited by 56

20 Years with SGBS cells - a versatile in vitro model of human adipocyte biology

Tews, D., Brenner, R. E., Siebert, R., Debatin, K., Fischer‐Posovszky, P., & Wabitsch, M. (2022) · International Journal of Obesity · doi:10.1038/s41366-022-01199-9 · Cited by 49

SnapShot: Brown and Beige Adipose Thermogenesis

Kissig, M., Shapira, S. N., & Seale, P. (2016) · Cell · doi:10.1016/j.cell.2016.06.038 · Cited by 49

Observed changes in brown, white, hepatic and pancreatic fat after bariatric surgery: Evaluation with MRI

Hui, S. C. N., Wong, S. K., Ai, Q. Y. H., Yeung, D. K. W., Ng, E. K., & Chu, C. W. (2018) · European Radiology · doi:10.1007/s00330-018-5611-z · Cited by 49

Oral gallic acid improves metabolic profile by modulating SIRT1 expression in obese mice brown adipose tissue: A molecular and bioinformatic approach

Paraíso, A. F., Sousa, J. N., Andrade, J. M. O., Santos, E. M., Lelis, D. D. F., de Paula, A. M. B., Martins, A. M. E. B.-L., Lima, W. J. N., Guimarães, A. L. S., Melo, G. A., et al. (2019) · Life Sciences · doi:10.1016/j.lfs.2019.116914 · Cited by 49

Novel adipokine asprosin modulates browning and adipogenesis in white adipose tissue

Miao, Y., Qin, H., Zhong, Y., Huang, K., & Rao, C. (2021) · Journal of Endocrinology · doi:10.1530/joe-20-0503 · Cited by 49

The Hypothalamic Preoptic Area and Body Weight Control

Yu, S., François, M., Huesing, C., & Münzberg, H. (2017) · Neuroendocrinology · doi:10.1159/000479875 · Cited by 48

Low temperature exposure induces browning of bone marrow stem cell derived adipocytes in vitro

Veličković, K., Leija, H. A. L., Bloor, I. D., Law, J., Sacks, H. S., Symonds, M. E., & Sottile, V. (2018) · Scientific Reports · doi:10.1038/s41598-018-23267-9 · Cited by 50

Allicin induces beige-like adipocytes via KLF15 signal cascade

Lee, C. G., Rhee, D. K., Kim, B. O., Um, S. H., & Pyo, S. (2018) · The Journal of Nutritional Biochemistry · doi:10.1016/j.jnutbio.2018.09.014 · Cited by 50

During Adipocyte Remodeling, Lipid Droplet Configurations Regulate Insulin Sensitivity through F-Actin and G-Actin Reorganization

Kim, J. I., Park, J., Ji, Y., Jo, K., Han, S. M., Sohn, J. H., Shin, K. C., Han, J. S., Jeon, Y. G., Nahmgoong, H., et al. (2019) · Molecular and Cellular Biology · doi:10.1128/mcb.00210-19 · Cited by 48

Curcumin improves insulin sensitivity and increases energy expenditure in high-fat-diet–induced obese mice associated with activation of FNDC5/irisin

Zou, T., Li, S., Wang, B., Wang, Z., Liu, Y., & You, J. (2021) · Nutrition · doi:10.1016/j.nut.2021.111263 · Cited by 48

Distinct AMPK-Mediated FAS/HSL Pathway Is Implicated in the Alleviating Effect of Nuciferine on Obesity and Hepatic Steatosis in HFD-Fed Mice

Xu, H., Lyu, X., Guo, X., Yang, H., Duan, L., Zhu, H., Pan, H., Gong, F., & Wang, L. (2022) · Nutrients · doi:10.3390/nu14091898 · Cited by 47

Glutathione Decrement Drives Thermogenic Program In Adipose Cells

Lettieri‐Barbato, D., Tatulli, G., Cannata, S. M., Bernardini, S., Aquilano, K., & Ciriolo, M. R. (2015) · Scientific Reports · doi:10.1038/srep13091 · Cited by 47

A New Role for Browning as a Redox and Stress Adaptive Mechanism?

Jeanson, Y., Carrière, A., & Casteilla, L. (2015) · Frontiers in Endocrinology · doi:10.3389/fendo.2015.00158 · Cited by 49

Serum PTHrP Predicts Weight Loss in Cancer Patients Independent of Hypercalcemia, Inflammation, and Tumor Burden

Hong, N., Yoon, H. J., Lee, Y., Kim, H. R., Lee, B., Rhee, Y., Kang, E. S., Soo, B., & Lee, H. C. (2016) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2015-3785 · Cited by 47

Wheat gluten intake increases weight gain and adiposity associated with reduced thermogenesis and energy expenditure in an animal model of obesity

Freire, R. H., Fernandes, L. R., da Silva, R. B., Coelho, B. S., Araújo, L. P., Ribeiro, L. S., Andrade, J. M. O., Lima, P. M. A., Araújo, R. S., Santos, S. H. S., et al. (2015) · International Journal of Obesity · doi:10.1038/ijo.2015.204 · Cited by 47

Green tea extract induces genes related to browning of white adipose tissue and limits weight-gain in high energy diet-fed rat

Chen, L., Chien, Y., Liang, C.-T., Chan, C., Fan, M., & Huang, H. (2017) · Food & Nutrition Research · doi:10.1080/16546628.2017.1347480 · Cited by 48

Interleukin‐15 in obesity and metabolic dysfunction: current understanding and future perspectives

Duan, Y., Li, F., Wang, W., Guo, Q., Wen, C., Li, Y., & Yin, Y. (2017) · Obesity Reviews · doi:10.1111/obr.12567 · Cited by 47

Autophagy in Adipocyte Browning: Emerging Drug Target for Intervention in Obesity

Ro, S., Jang, Y., Bae, J., Kim, I. M., Schaecher, C., & Shomo, Z. D. (2019) · Frontiers in Physiology · doi:10.3389/fphys.2019.00022 · Cited by 47

Resveratrol promotes white adipocytes browning and improves metabolic disorders in Sirt1‐dependent manner in mice

Li, Z., Zhang, Z., Ke, L., Sun, Y., Li, W., Feng, X., Zhu, W., & Chen, S. (2020) · The FASEB Journal · doi:10.1096/fj.201902222r · Cited by 47

A transcribed ultraconserved noncoding RNA, uc.417, serves as a negative regulator of brown adipose tissue thermogenesis

Cui, X., You, L., Li, Y., Zhu, L., Zhang, F., Xie, K., Cao, Y., Ji, C., & Guo, X. (2016) · The FASEB Journal · doi:10.1096/fj.201600694r · Cited by 46

An emerging role for epigenetic regulation of Pgc-1α expression in environmentally stimulated brown adipose thermogenesis

Gill, J. A., & Merrill, M. A. L. (2017) · Current Zoology · doi:10.1093/eep/dvx009 · Cited by 48

Lyophilized Maqui (Aristotelia chilensis) Berry Induces Browning in the Subcutaneous White Adipose Tissue and Ameliorates the Insulin Resistance in High Fat Diet-Induced Obese Mice

Sandoval, V., Femenias, A., Martínez‐Garza, Ú., Sanz‐Lamora, H., Castagnini, J. M., Quifer‐Rada, P., Lamuela-Raventós, R. M., Marrero, P. F., Haro, D., & Relat, J. (2019) · Antioxidants · doi:10.3390/antiox8090360 · Cited by 46

Sex differences on adipose tissue remodeling: from molecular mechanisms to therapeutic interventions

Moreira‐Pais, A., Ferreira, R. M., Neves, J. S., Vitorino, R. M. P., Moreira‐Gonçalves, D., & Nogueira‐Ferreira, R. (2020) · Journal of Molecular Medicine · doi:10.1007/s00109-020-01890-2 · Cited by 51

Simvastatin-Loaded Polymeric Nanoparticles: Targeting Inflammatory Macrophages for Local Adipose Tissue Browning in Obesity Treatment

Mohaghegh, N., Ahari, A. F., Buttles, C., Davani, S., Hoang, H., Huang, Q., Huang, Y., Hosseinpour, B., Abbasgholizadeh, R., Cottingham, A. L., et al. (2024) · ACS Nano · doi:10.1021/acsnano.4c10742 · Cited by 48

Reduced adipose tissue H 2 S in obesity

Katsouda, A., Szabó, C., & Papapetropoulos, A. (2017) · Pharmacological Research · doi:10.1016/j.phrs.2017.09.023 · Cited by 45

Extract of the Microalga Nitzschia laevis Prevents High‐Fat‐Diet‐Induced Obesity in Mice by Modulating the Composition of Gut Microbiota

Guo, B., Liu, B., Wei, H., Cheng, K., & Chen, F. (2018) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.201800808 · Cited by 45

Looking on the “brite” side exercise-induced browning of white adipose tissue

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Role of thermogenic adipose tissue in lipid metabolism and atherosclerotic cardiovascular disease: lessons from studies in mice and humans

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