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Insulin Resistance and a Diabetes Mellitus-Like Syndrome in Mice Lacking the Protein Kinase Akt2 (PKBβ)

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Mutations in PTPN11, encoding the protein tyrosine phosphatase SHP-2, cause Noonan syndrome

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A Common Allele on Chromosome 9 Associated with Coronary Heart Disease

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Identification of ALK as a major familial neuroblastoma predisposition gene

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BRAF mutation predicts sensitivity to MEK inhibition

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Mutations in the transmembrane domain of FGFR3 cause the most common genetic form of dwarfism, achondroplasia.

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A recurrent mutation in the BMP type I receptor ACVR1 causes inherited and sporadic fibrodysplasia ossificans progressiva

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Mutations of the gene encoding the protein kinase A type I-α regulatory subunit in patients with the Carney complex

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Acquired mutation of the tyrosine kinase JAK2 in human myeloproliferative disorders

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Multiple, Distinct Forms of Bovine and Human Protein Kinase C Suggest Diversity in Cellular Signaling Pathways

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Evolution of protein kinase signaling from yeast to man

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Apert syndrome results from localized mutations of FGFR2 and is allelic with Crouzon syndrome

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Oncogenic mutations of ALK kinase in neuroblastoma

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The Catalogue of Somatic Mutations in Cancer (COSMIC)

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Somatic and germline activating mutations of the ALK kinase receptor in neuroblastoma

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Activating mutations in ALK provide a therapeutic target in neuroblastoma

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A TEL-JAK2 Fusion Protein with Constitutive Kinase Activity in Human Leukemia

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Mutations in the fibroblast growth factor receptor 2 gene cause Crouzon syndrome

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Genome-wide association study of restless legs syndrome identifies common variants in three genomic regions

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BMP type I receptor inhibition reduces heterotopic ossification

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A common mutation in the fibroblast growth factor receptor 1 gene in Pfeiffer syndrome

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Colocalization of X-Linked Agammaglobulinemia and X-Linked Immunodeficiency Genes

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Germline KRAS and BRAF mutations in cardio-facio-cutaneous syndrome

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Germline Mutations in Genes Within the MAPK Pathway Cause Cardio-facio-cutaneous Syndrome

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A Family with Severe Insulin Resistance and Diabetes Due to a Mutation in AKT2

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RET tyrosine kinase signaling in development and cancer.

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Mutations that cause osteoglophonic dysplasia define novel roles for FGFR1 in bone elongation.

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Identical mutations in three different fibroblast growth factor receptor genes in autosomal dominant craniosynostosis syndromes

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Whole-genome association study identifies <i>STK39</i> as a hypertension susceptibility gene

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Mutations in fibroblast growth factor receptor 1 cause both Kallmann syndrome and normosmic idiopathic hypogonadotropic hypogonadism

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Missense Mutations in the Regulatory Domain of PKCγ: A New Mechanism for Dominant Nonepisodic Cerebellar Ataxia

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The hallmark of AGC kinase functional divergence is its C-terminal tail, a cis-acting regulatory module

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Mouse Ror2 receptor tyrosine kinase is required for the heart development and limb formation

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Integrin-linked kinase regulates phosphorylation of serine 473 of protein kinase B by an indirect mechanism

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