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Human memory T cells: generation, compartmentalization and homeostasis
Open accessAbstract
Memory T cells constitute the most abundant lymphocyte population in the body for the majority of a person's lifetime; however, our understanding of memory T cell generation, function and maintenance mainly derives from mouse studies, which cannot recapitulate the exposure to multiple pathogens that occurs over many decades in humans. In this Review, we discuss studies focused on human memory T cells that reveal key properties of these cells, including subset heterogeneity and diverse tissue residence in multiple mucosal and lymphoid tissue sites. We also review how the function and the adaptability of human memory T cells depend on spatial and temporal compartmentalization.
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“In such cases, memory B and T cells can be rapidly reactivated, resulting in the enhanced control of initial viral replication and limiting viral dissemination in the host (24, 25).”
From mRNA vaccines induce durable immune memory to SARS-CoV-2 and variants of concern (2021) · cites this paper as [25]
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“Seeding into tissues occurs in childhood, and the resident population persists throughout adulthood”
From Successful and Maladaptive T Cell Aging (2017) · cites this paper as Farber et al., 2014
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“Resident memory T cells in lungs, skin, and submucosal sites account for a large fraction of memory cells numbering more than 5 × 1010 cells in an individual.”
From Successful and Maladaptive T Cell Aging (2017) · cites this paper as Farber et al., 2014
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Two subsets of memory T lymphocytes with distinct homing potentials and effector functions
Sallusto, F., Lenig, D., Förster, R., Lipp, M., & Lanzavecchia, A. (1999) · Nature · doi:10.1038/44385 · Cited by 5,846
Phenotypic Analysis of Antigen-Specific T Lymphocytes
Altman, J. D., Moss, P. A. H., Goulder, P. J. R., Barouch, D. H., McHeyzer-Williams, M. G., Bell, J. I., McMichael, A. J., & Davis, M. M. (1996) · Science · doi:10.1126/science.274.5284.94 · Cited by 3,544
Central Memory and Effector Memory T Cell Subsets: Function, Generation, and Maintenance
Sallusto, F., Geginat, J., & Lanzavecchia, A. (2004) · Annual Review of Immunology · doi:10.1146/annurev.immunol.22.012703.104702 · Cited by 3,067
Bendall, S. C., Simonds, E. F., Qiu, P., Amir, E.-A. D., Krutzik, P. O., Finck, R., Bruggner, R. V., Melamed, R., Trejo, A., Ornatsky, O. I., et al. (2011) · Science · doi:10.1126/science.1198704 · Cited by 2,279
A human memory T cell subset with stem cell–like properties
Gattinoni, L., Lugli, E., Ji, Y., Pos, Z., Paulos, C. M., Quigley, M. F., Almeida, J. R., Gostick, E., Yu, Z., Carpenito, C., et al. (2011) · Nature Medicine · doi:10.1038/nm.2446 · Cited by 1,974
Self-citationPreferential Localization of Effector Memory Cells in Nonlymphoid Tissue
Masopust, D., Vezys, V., Marzo, A. L., & Lefrançois, L. (2001) · Science · doi:10.1126/science.1058867 · Cited by 1,952
Counting Antigen-Specific CD8 T Cells: A Reevaluation of Bystander Activation during Viral Infection
Murali‐Krishna, K., Altman, J. D., Suresh, M., Sourdive, D. J. D., Zajac, A. J., Miller, J. D., Slansky, J. E., & Ahmed, R. (1998) · Immunity · doi:10.1016/s1074-7613(00)80470-7 · Cited by 1,918
HIV reservoir size and persistence are driven by T cell survival and homeostatic proliferation
Chomont, N., Far, M. E., Ancuța, P., Trautmann, L., Procopio, F. A., Yassine‐Diab, B., Boucher, G., Boulassel, M., Ghattas, G., Brenchley, J. M., et al. (2009) · Nature Medicine · doi:10.1038/nm.1972 · Cited by 1,775
Reciprocal interactions of the intestinal microbiota and immune system
Maynard, C. L., Elson, C. O., Hatton, R. D., & Weaver, C. T. (2012) · Nature · doi:10.1038/nature11551 · Cited by 1,598
T-cell quality in memory and protection: implications for vaccine design
Seder, R. A., Darrah, P. A., & Roederer, M. (2008) · Nature reviews. Immunology · doi:10.1038/nri2274 · Cited by 1,565
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Dóra, D., Krencz, I., Sebestyén, A. R., Szalai, F., Roskó, B., Kamel, Y., Mokánszki, B., Király, P., Gálffy, G., & Lohinai, Z. (2026) · Research Square · doi:10.21203/rs.3.rs-11025245/v1
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Naeij, M. H., Ebrahimifard, M., Iravani, M., & Ghorbaninezhad, F. (2026) · Medical Hypotheses · doi:10.1016/j.mehy.2026.112215
Ran, J., Zhang, W., Zhang, W., Huang, H., 龚乐君, Yin, S., Chen, Y., Wang, A., Min, H., Zhu, L., et al. (2026) · Emerging Microbes & Infections · doi:10.1080/22221751.2026.2746253
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Single-cell transcriptomics of human T cells
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Metadata
- Authors
- Farber, D. L., Yudanin, N. A., & Restifo, N. P.
- Affiliations
- Columbia University Irving Medical Center (US)
- National Institutes of Health (US)
- Venue
- Nature Reviews Immunology
- Published
- 2013-12-13
- Volume
- 14
- Issue
- 1
- Pages
- 24-35
- ISSN
- 1474-1733 (ISSN-L)
- 1474-1741
- PMC
- PMC4032067
- OpenAlex
- W2033505817
- Cited by
- 897
- References
- 153
- Citations by year
- 2026: 50 · 2025: 53 · 2024: 81 · 2023: 64 · 2022: 78 · 2021: 91 · 2020: 85 · 2019: 86 · 2018: 78 · 2017: 83 · 2016: 69 · 2015: 54 · 2014: 25
- FWCI
- 4.30
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Licence
- Locations
- Nature reviews. Immunology (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institutes of Health
- National Institute of Allergy and Infectious Diseases (U01AI100119, AI106697, U19AI083022, P01AI106697, R01AI100119, AI100119, AI 083022)
- Topics
- Life Sciences › Immunology and Microbiology › Immunology › T-cell and B-cell Immunology
- Life Sciences › Immunology and Microbiology › Immunology › Psoriasis: Treatment and Pathogenesis
- Life Sciences › Immunology and Microbiology › Immunology › Immunotherapy and Immune Responses
- Keywords
- memory T cells, immunological memory, human T cells, T cell subsets, T cell heterogeneity, mucosal immunity, lymphoid tissue, spatial compartmentalization, T cell homeostasis, T cell generation
- MeSH terms
- Animals, Antigens, Cross Reactions, Homeostasis, Humans, Immunologic Memory, Lymphoid Tissue, Vaccines, T-Lymphocyte Subsets, Models, Immunological, Immunity, Mucosal, Mice, Adaptive Immunity, Microbiota
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