Mechanisms of mitophagy

Youle, Richard J., Narendra, Derek P.·2011·Nature Reviews Molecular Cell Biology

Cited by (1,021)

Items 101–200 of 1,021

  1. Selective autophagy of intracellular organelles: Recent research advances
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  2. Secretory autophagy
    Marisa Ponpuak, Michael A. Mandell, Tomonori Kimura, Santosh Chauhan, Cédric Cleyrat, Vojo P. Deretic · 2015 · Current Opinion in Cell Biology
  3. Mitochondria and Endothelial Function
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  4. Mitochondrial Dysfunction in Cancer
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  5. Treatment of nonalcoholic fatty liver disease: role of AMPK
    Brennan K. Smith, Katarina Marcinko, Eric M. Desjardins, James Lally, Rebecca J. Ford, Gregory R. Steinberg · 2016 · American Journal of Physiology-Endocrinology and Metabolism
  6. Lipophagy: Connecting Autophagy and Lipid Metabolism
    Singh, Rajat, Cuervo, Ana Maria · 2012 · International Journal of Cell Biology
  7. The endoplasmic reticulum–mitochondria connection: One touch, multiple functions
    Saverio Marchi, Simone Patergnani, Paolo Pinton · 2013 · Biochimica et Biophysica Acta (BBA) - Bioenergetics
  8. Is mitochondrial DNA content a potential biomarker of mitochondrial dysfunction?
    Afshan N. Malik, Anna Czajka · 2012 · Mitochondrion
  9. Mitofusins, from Mitochondria to Metabolism
    Emilie Schrepfer, Luca Scorrano · 2016 · Molecular Cell
  10. Autophagy and apoptosis: what is the connection?
    Jacob M. Gump, Andrew M. Thorburn · 2011 · Trends in Cell Biology
  11. Integration of cellular bioenergetics with mitochondrial quality control and autophagy
    Bradford G. Hill, Gloria A. Benavides, Jack R. Lancaster, Scott W. Ballinger, Louis Dell’Italia, Jianhua Zhang, Victor M. Darley-Usmar · 2012 · Biological Chemistry
  12. De novo mutations in the autophagy gene WDR45 cause static encephalopathy of childhood with neurodegeneration in adulthood
    Saitsu, Hirotomo, Nishimura, Taki, Muramatsu, Kazuhiro, Kodera, Hirofumi, Kumada, Satoko, Sugai, Kenji, Kasai-Yoshida, Emi, Sawaura, Noriko, Nishida, Hiroya, Hoshino, Ai et al. · 2013 · Nature Genetics
  13. Mitochondrial oxidative stress in aging and healthspan
    Dao‐Fu Dai, Ying Ann Chiao, David Joseph Marcinek, Hazel H. Szeto, Peter S. Rabinovitch · 2014 · Longevity & Healthspan
  14. New insights into the function and regulation of mitochondrial fission
    Hidenori Otera, Naotada Ishihara, Katsuyoshi Mihara · 2013 · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
  15. Mechanism of phospho-ubiquitin-induced PARKIN activation
    Tobias Wauer, Michal Šimíček, Alexander F. Schubert, David Komander · 2015 · Nature
  16. Degradation of Paternal Mitochondria by Fertilization-Triggered Autophagy in C. elegans Embryos
    Miyuki Sato, Ken Sato · 2011 · Science
  17. Mitochondria and cell signalling
    Tait, Stephen W. G., Green, Douglas R. · 2012 · Journal of Cell Science
  18. Inflammasome activation leads to Caspase-1–dependent mitochondrial damage and block of mitophagy
    Jiu-Jiu Yu, Hajime Nagasu, T. Murakami, Hai Hoang, L. Broderick, H. Hoffman, Tiffany Horng · 2014 · Proceedings of the National Academy of Sciences of the United States of America
  19. Complex interplay between autophagy and oxidative stress in the development of pulmonary disease
    Wojciech Ornatowski, Qing Lü, Manivannan Yegambaram, Alejandro Garcia Flores, Evgeny A. Zemskov, Emin Maltepe, Jeffrey R. Fineman, Ting Wang, Stephen M. Black · 2020 · Redox Biology
  20. Drp1-Dependent Mitochondrial Autophagy Plays a Protective Role Against Pressure Overload–Induced Mitochondrial Dysfunction and Heart Failure
    Akihiro Shirakabe, Peiyong Zhai, Yoshiyuki Ikeda, Toshiro Saito, Yasuhiro Maejima, Chiao‐Po Hsu, Masatoshi Nomura, Kensuke Egashira, Beth Levine, Junichi Sadoshima · 2016 · Circulation
  21. Mitochondrial dynamics in neurodegeneration
    Kie Itoh, Ken Nakamura, Miho Iijima, Hiromi Sesaki · 2012 · Trends in Cell Biology
  22. Metabolic checkpoints in activated T cells
    Ruoning Wang, Douglas R. Green · 2012 · Nature Immunology
  23. Functional Impairment in Miro Degradation and Mitophagy Is a Shared Feature in Familial and Sporadic Parkinson’s Disease
    Chung-Han Hsieh, Atossa Shaltouki, Ashley E. Gonzalez, Alexandre Bettencourt da Cruz, Lena F. Burbulla, Erica St. Lawrence, Birgitt Schüle, Dimitri Krainc, Theo D. Palmer, Xinnan Wang · 2016 · Cell stem cell
  24. Mitochondrial Function, Biology, and Role in Disease
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  25. Oxidative Stress, Redox Signaling, and Autophagy: Cell Death Versus Survival
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  26. Control of autophagy as a therapy for neurodegenerative disease
    Harry Harris, David Chaim Rubinsztein · 2011 · Nature Reviews Neurology
  27. Defects in trafficking bridge Parkinson’s disease pathology and genetics
    Abeliovich, Asa, Gitler, Aaron D. · 2016 · Nature
  28. Exosomes and Autophagy: Coordinated Mechanisms for the Maintenance of Cellular Fitness
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  29. Organelle-specific autophagy in inflammatory diseases: a potential therapeutic target underlying the quality control of multiple organelles
    Yao, Ren-Qi, Ren, Chao, Xia, Zhao-Fan, Yao, Yong-Ming · 2021 · Autophagy
  30. DNA Damage, DNA Repair, Aging, and Neurodegeneration
    Scott Maynard, Evandro Fei Fang, Morten Scheibye‐Knudsen, Deborah L. Croteau, Vilhelm A. Bohr · 2015 · Cold Spring Harbor Perspectives in Medicine
  31. Functions of autophagy in normal and diseased liver
    Mark J. Czaja, Wen‐Xing Ding, Terrence M. Donohue, Scott L. Friedman, Kim Js, Masaaki Komatsu, John J. Lemasters, Antoinette Lemoine, Jiandie D. Lin, Jing‐hsiung James Ou et al. · 2013 · Autophagy
  32. Autophagy promotes the survival of dormant breast cancer cells and metastatic tumour recurrence
    Laura Vera Ramírez, Suman Kumar Vodnala, Ryan Nini, Kent W. Hunter, Jeffrey E. Green · 2018 · Nature Communications
  33. Structure of the human ATG12~ATG5 conjugate required for LC3 lipidation in autophagy
    Chinatsu Otomo, Zoltan Metlagel, Giichi Takaesu, Takanori Otomo · 2012 · Nature Structural & Molecular Biology
  34. Activation of Autophagy Protects Against Acetaminophen–Induced Hepatotoxicity
    Hong‐Min Ni, Abigail B. Bockus, Nikki Boggess, Hartmut Jaeschke, Wen‐Xing Ding · 2011 · Hepatology
  35. ROS-induced mitochondrial depolarization initiates PARK2/PARKIN-dependent mitochondrial degradation by autophagy
    Yuqing Wang, Yulia Nartiss, Boris Steipe, G. Angus McQuibban, Peter Kijun Kim · 2012 · Autophagy
  36. Mito‐Bomb: Targeting Mitochondria for Cancer Therapy
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  37. Parkin‐independent mitophagy requires Drp1 and maintains the integrity of mammalian heart and brain
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  38. Mitochondria: from cell death executioners to regulators of cell differentiation
    Atsuko Kasahara, Luca Scorrano · 2014 · Trends in Cell Biology
  39. Mitochondrial quality control: a matter of life and death for neurons
    Elena I. Rugarli, Thomas Langer · 2012 · The EMBO Journal
  40. The Mitochondrial Basis of Aging and Age-Related Disorders
    Sarika Srivastava · 2017 · Genes
  41. The Delicate Balance Between Secreted Protein Folding and Endoplasmic Reticulum-Associated Degradation in Human Physiology
    Christopher J. Guerriero, Jeffrey L. Brodsky · 2012 · Physiological Reviews
  42. Mitochondrial calcium exchange in physiology and disease
    Joanne F. Garbincius, John W. Elrod · 2021 · Physiological Reviews
  43. PHB2 (prohibitin 2) promotes PINK1-PRKN/Parkin-dependent mitophagy by the PARL-PGAM5-PINK1 axis
    Chaojun Yan, Longlong Gong, Li Chen, Meng Xu, Hussein Abou‐Hamdan, Mingliang Tang, Laurent Désaubry, Zhiyin Song · 2019 · Autophagy
  44. Minimizing the damage: repair pathways keep mitochondrial DNA intact
    Lawrence Kazak, Aurelio Reyes, Ian James Holt · 2012 · Nature Reviews Molecular Cell Biology
  45. Emerging therapies for idiopathic pulmonary fibrosis, a progressive age-related disease
    Ana Lucia Mora, Mauricio Rojas, Annie Pardo, Moisés Selman · 2017 · Nature Reviews Drug Discovery
  46. Mechanistic insights into selective autophagy pathways: lessons from yeast
    Jean‐Claude Farré, Suresh Ellappa Subramani · 2016 · Nature Reviews Molecular Cell Biology
  47. Multiple Roles of the Small GTPase Rab7
    Flora Guerra, Cecilia Bucci · 2016 · Cells
  48. Mitophagy programs: mechanisms and physiological implications of mitochondrial targeting by autophagy
    Anne Hamacher‐Brady, Nathan Ryan Brady · 2015 · Cellular and Molecular Life Sciences
  49. Inhibiting NLRP3 inflammasome attenuates apoptosis in contrast-induced acute kidney injury through the upregulation of HIF1A and BNIP3-mediated mitophagy
    Qisheng Lin, Shu Li, Na Jiang, Haijiao Jin, Xinghua Shao, Xuying Zhu, Jingkui Wu, Minfang Zhang, Zhen Zhang, Jianxiao Shen et al. · 2020 · Autophagy
  50. Autophagy in acute kidney injury
    Kaushal, Gur P., Shah, Sudhir V. · 2016 · Kidney International
  51. Autophagy: A Critical Regulator of Cellular Metabolism and Homeostasis
    Stefan W. Ryter, Suzanne M. Cloonan, Augustine M.K. Choi · 2013 · Molecules and Cells
  52. Mitochondrial quality control mechanisms as molecular targets in cardiac ageing
    Anna Picca, Robert T. Mankowski, Jonathon L. Burman, Luca Donisi, Kim Js, Emanuele Marzetti, Christiaan Leeuwenburgh · 2018 · Nature Reviews Cardiology
  53. Pharmacological approaches to restore mitochondrial function
    Andreux, Pénélope A., Houtkooper, Riekelt H., Auwerx, Johan · 2013 · Nature Reviews Drug Discovery
  54. Heterogeneity of the gut microbiome in mice: guidelines for optimizing experimental design
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  55. Mitochondrial dysfunction associated with increased oxidative stress and α-synuclein accumulation in PARK2 iPSC-derived neurons and postmortem brain tissue
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  56. Tau Promotes Neurodegeneration via DRP1 Mislocalization In Vivo
    DuBoff, Brian, Götz, Jürgen, Feany, Mel B. · 2012 · Neuron
  57. Autophagy in liver diseases: A review
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  58. Autophagy provides metabolic substrates to maintain energy charge and nucleotide pools in Ras-driven lung cancer cells
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  59. Parkinson's Disease–Associated Kinase PINK1 Regulates Miro Protein Level and Axonal Transport of Mitochondria
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  60. Regulation of autophagy by mTOR-dependent and mTOR-independent pathways: autophagy dysfunction in neurodegenerative diseases and therapeutic application of autophagy enhancers
    Sovan Sarkar · 2013 · Biochemical Society Transactions
  61. The role of mitochondria in aging
    Jang, Ji Yong, Blum, Arnon, Liu, Jie, Finkel, Toren · 2018 · Journal of Clinical Investigation
  62. Mitochondrial dysfunction in ataxia-telangiectasia
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  63. A current perspective of autophagosome biogenesis
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  64. Mitophagy in neurodegeneration and aging
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  65. The Roles of Mitochondrial Damage-Associated Molecular Patterns in Diseases
    Kiichi Nakahira, Shu Hisata, Augustine M.K. Choi · 2015 · Antioxidants and Redox Signaling
  66. PINK1 Loss-of-Function Mutations Affect Mitochondrial Complex I Activity via NdufA10 Ubiquinone Uncoupling
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  67. Mitochondrial fusion/fission dynamics in neurodegeneration and neuronal plasticity
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  68. Ubiquitin-Like Proteins
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  69. Signaling the mitochondrial unfolded protein response
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  70. Unbiased screen for interactors of leucine-rich repeat kinase 2 supports a common pathway for sporadic and familial Parkinson disease
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  71. A fluorescence-based imaging method to measure in vitro and in vivo mitophagy using mt-Keima
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  72. Reconstitution of Mitochondria Derived Vesicle Formation Demonstrates Selective Enrichment of Oxidized Cargo
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  73. MitoCeption as a new tool to assess the effects of mesenchymal stem/stromal cell mitochondria on cancer cell metabolism and function
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  74. Stress‐induced OMA1 activation and autocatalytic turnover regulate OPA1‐dependent mitochondrial dynamics
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  75. MitoCPR—A surveillance pathway that protects mitochondria in response to protein import stress
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  76. Mouse Cre-LoxP system: general principles to determine tissue-specific roles of target genes
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  77. Autophagy
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  78. Parkin overexpression during aging reduces proteotoxicity, alters mitochondrial dynamics, and extends lifespan
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  79. Structure of the human Parkin ligase domain in an autoinhibited state
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  80. Repairing mitochondrial dysfunction in disease
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  81. Autophagy and Autophagy-Related Diseases: A Review
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  82. The mitochondrial permeability transition pore: a mystery solved?
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  83. Miro proteins coordinate microtubule‐ and actin‐dependent mitochondrial transport and distribution
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  84. Regenerative abilities of mesenchymal stem cells through mitochondrial transfer
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  85. Parkin and PINK1 function in a vesicular trafficking pathway regulating mitochondrial quality control
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  86. Protecting the mitochondrial powerhouse
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  87. Mitophagy defects arising from BNip3 loss promote mammary tumor progression to metastasis
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  88. The ATG1/ATG13 Protein Kinase Complex Is Both a Regulator and a Target of Autophagic Recycling in Arabidopsis
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  90. TBK1 controls autophagosomal engulfment of polyubiquitinated mitochondria through p62/SQSTM1 phosphorylation
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  96. Cellular metabolic and autophagic pathways: Traffic control by redox signaling
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  99. The pharmacological regulation of cellular mitophagy
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  100. Mitochondrial Channels: Ion Fluxes and More
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