The DOI matches its Crossref record; 117 of the 117 references it cites were found in a registry or an index.
Exploring mechanisms of FGF signalling through the lens of structural biology
Open accessAbstract
Fibroblast growth factors (FGFs) mediate a broad range of functions in both the developing and adult organism. The accumulated wealth of structural information on the FGF signalling pathway has begun to unveil the underlying molecular mechanisms that modulate this system to generate a myriad of distinct biological outputs in development, tissue homeostasis and metabolism. At the ligand and receptor level, these mechanisms include alternative splicing of the ligand (FGF8 subfamily) and the receptor (FGFR1–FGFR3), ligand homodimerization (FGF9 subfamily), site-specific proteolytic cleavage of the ligand (FGF23), and interaction of the ligand and the receptor with heparan sulphate cofactor and Klotho co-receptor.
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Cites
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Cited by
Remodelling the extracellular matrix in development and disease
Bonnans, C., Chou, J., & Werb, Z. (2014) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm3904 · Cited by 4,367
The Fibroblast Growth Factor signaling pathway
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“A novel Fibroblast Growth Factor receptor-5 preferentially expressed in the pancreas(1).”
BackgroundFGF/FGFR signaling in health and disease
Xie, Y., Su, N., Yang, J., Tan, Q., Huang, S., Jin, M., Ni, Z., Zhang, B., Zhang, D., Luo, F., et al. (2020) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-020-00222-7 · Cited by 904
The cellular and molecular mechanisms of vertebrate lens development
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Metabolic fibroblast growth factors (FGFs): Mediators of energy homeostasis
Markan, K. R., & Potthoff, M. J. (2016) · Seminars in Cell & Developmental Biology · doi:10.1016/j.semcdb.2015.09.021 · Cited by 103
Metadata
- Authors
- Goetz, R., & Mohammadi, M.
- Venue
- Nature Reviews Molecular Cell Biology
- Published
- 2013-02-13
- Volume
- 14
- Issue
- 3
- Pages
- 166-180
- ISSN
- 1471-0072 (ISSN-L)
- 1471-0080
- OpenAlex
- W1965358479
- Cited by
- 573
- References
- 117
- FWCI
- 3.54
- Type
- journal article
- Language
- en
- Open access
- green
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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