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Why do many psychiatric disorders emerge during adolescence?
Open accessAbstract
The peak age of onset for many psychiatric disorders is adolescence, a time of remarkable physical and behavioural changes. The processes in the brain that underlie these behavioural changes have been the subject of recent investigations. What do we know about the maturation of the human brain during adolescence? Do structural changes in the cerebral cortex reflect synaptic pruning? Are increases in white-matter volume driven by myelination? Is the adolescent brain more or less sensitive to reward? Finding answers to these questions might enable us to further our understanding of mental health during adolescence.
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“this developmental period is also associated with increased risk taking, accidents, and susceptibility to psychopathology (Crone et al., 2016; Giedd et al., 2008; Kessler, Berglund, et al., 2005; Steinberg, 2007).”
From Atypical interoception as a common risk factor for psychopathology: A review (2021) · cites this paper as Giedd et al., 2008
Experimental — accuracy not yet measuredThe source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
In the citing paper
“Despite these limitations, it is thought that reductions in gray matter volume might reflect synaptic reorganization and/or increases in white matter integrity (Paus et al. 2008).”
From Is Adolescence a Sensitive Period for Sociocultural Processing? (2014) · cites this paper as Paus et al. 2008
Experimental — accuracy not yet measuredThe cited source says what the claim attributes to it.
In the citing paper
“Further, adolescence is a time of increased vulnerability to develop anxiety or depressive symptoms (Paus et al., 2008)”
From Effects of traumatic experiences on obsessive-compulsive and internalizing symptoms: The role of avoidance and mindfulness. (2018) · cites this paper as Paus et al., 2008
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In the citing paper
“Faced with this cocktail of stressful new experiences on a background of unstable hormones and altered brain function, it is perhaps unsurprising that adolescents are vulnerable to mental health problems (Kessler et al., 2005;Lee et al., 2014;Paus et al., 2008).”
From The Microbiota-Gut-Brain Axis (2019) · cites this paper as Paus et al., 2008
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In the citing paper
“Magnetic Resonance Imaging (MRI) studies in humans have shown that white matter volume steadily increases from childhood into adolescence, accompanied by changes in Diffusion Weighted Imaging (DWI) parameters, suggesting that maturation of axons/myelin sheaths represents an ongoing (developmental) process (Paus et al., 2008).”
From Acceptance and Commitment Therapy and white matter plasticity in individuals with subclinical depression and psychotic experiences: A Randomised Controlled Trial (2023) · cites this paper as Paus et al., 2008
In the citing paper
“Early abnormalities of maturational changes appear from the ectodermal phase to the first year after birth (first-wave hits) 49 .”
From Preventive psychiatry: a blueprint for improving the mental health of young people (2021) · cites this paper as [49]
In the citing paper
“Depression typically does not emerge until the adolescent period despite early environmental insults, and this relatively late onset of depression has been documented in both human and non-human animal models of ELS”
From Reduced nucleus accumbens reactivity and adolescent depression following early-life stress (2013) · cites this paper as Paus et al., 2008
In the citing paper
“It has been well established in the literature that children, and especially adolescents, are susceptible to experiencing mental health problems, while most mental disorders have their onset in this age period [51,52].”
From Exploring the Impact of COVID-19 on Mental Health Outcomes in Children and Adolescents: A Systematic Review (2020) · cites this paper as [52]
In the citing paper
“It has been well established in the literature that children, and especially adolescents, are susceptible to experiencing mental health problems, while most mental disorders have their onset in this age period [51,52].”
From Exploring the Impact of COVID-19 on Mental Health Outcomes in Children and Adolescents: A Systematic Review (2020) · cites this paper as [52]
In the citing paper
“It is important to resolve these inconsistencies to gain a better understanding of the neural correlates of risky behaviors and risk factors for psychopathology that emerge during adolescence (Galvan, 2010; Paus et al., 2008).”
From A systematic review of fMRI reward paradigms used in studies of adolescents vs. adults: The impact of task design and implications for understanding neurodevelopment (2013) · cites this paper as Paus et al., 2008
In the citing paper
“Instead, grey matter decline may reflect an artefact of increased myelination of intra-cortical axons (Bourgeois and Rakic, 1993, Paus, 2005, Paus et al., 2008).”
From Neurocognitive bases of emotion regulation development in adolescence (2015) · cites this paper as Paus et al., 2008
In the citing paper
“Adolescence is a period of increased emotional reactivity and psychopathology.”
From Neurocognitive bases of emotion regulation development in adolescence (2015) · cites this paper as Paus et al., 2008
In the citing paper
“Evidence suggests that structural brain development in brain regions subserving emotion regulation continues into adulthood (Paus et al., 2008).”
From Neurocognitive bases of emotion regulation development in adolescence (2015) · cites this paper as Paus et al., 2008
In the citing paper
“Psychopathology associated with internalising symptoms notably increases during the adolescent years (Lee et al., 2014, Paus et al., 2008).”
From Neurocognitive bases of emotion regulation development in adolescence (2015) · cites this paper as Paus et al., 2008
In the citing paper
“Given that the onset of many psychiatric conditions occurs during adolescence (72), and that genotype variations have been associated with the incidence of developmental psychiatric disorders, elucidating the role of genetics in determining brain function during childhood and adolescence is critical to our understanding of the development of these disorders.”
From Influence of the COMT genotype on working memory and brain activity changes during development (2011) · cites this paper as [72]
In the citing paper
“We then analyzed transcriptional dynamics in each of the neuron subtypes between adolescence8,9 (P21) and adulthood (P60) in mouse, a critical postnatal period believed to be associated with greatly increased neuroplasticity, and manifestation of most neuropsychiatric disorders7,10.”
From Cell type-specific transcriptional programs in mouse prefrontal cortex during adolescence and addiction (2019) · cites this paper as [10]
In the citing paper
“transcriptional plasticity during this period is believed to play a key role in disease pathogenesis10.”
From Cell type-specific transcriptional programs in mouse prefrontal cortex during adolescence and addiction (2019) · cites this paper as [10]
In the citing paper
“Since initial manifestation of these disorders frequently occur during adolescence”
From Cell type-specific transcriptional programs in mouse prefrontal cortex during adolescence and addiction (2019) · cites this paper as [10]
In the citing paper
“Many psychiatric disorders associated with genetic defects surface during adolescence10.”
From Cell type-specific transcriptional programs in mouse prefrontal cortex during adolescence and addiction (2019) · cites this paper as [10]
In the citing paper
“A potential imbalance between the time courses of cortical and subcortical neural circuitry development is one hypothesized mechanism of adolescent vulnerability to disorders such as SAD (Paus et al., 2008).”
From Gaining insight into adolescent vulnerability for social anxiety from developmental cognitive neuroscience (2014) · cites this paper as Paus et al., 2008
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Cites
Kessler, R. C., Berglund, P., Demler, O., Jin, R., Merikangas, K. R., & Walters, E. E. (2005) · Archives of General Psychiatry · doi:10.1001/archpsyc.62.6.593 · Cited by 20,391
Rizzolatti, G., & Craighero, L. (2004) · Annual Review of Neuroscience · doi:10.1146/annurev.neuro.27.070203.144230 · Cited by 7,433
Neurophysiological investigation of the basis of the fMRI signal
Logothetis, N. K., Pauls, J., Augath, M., Trinath, T., & Oeltermann, A. (2001) · Nature · doi:10.1038/35084005 · Cited by 6,551
Dynamic mapping of human cortical development during childhood through early adulthood
Gogtay, N., Giedd, J. N., Lusk, L., Hayashi, K. M., Greenstein, D., Vaituzis, A. C., Nugent, T. F., Herman, D. H., Clasen, L. S., Toga, A. W., et al. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0402680101 · Cited by 5,604 · cited 1×
“Plots of grey-matter density (top graph) are based on data by Gogtay et al.(8) and illustrate the local grey-matter density in th mid-dorsolateral”
MethodSelf-citationBrain development during childhood and adolescence: a longitudinal MRI study
Giedd, J. N., Blumenthal, J., Jeffries, N. O., Castellanos, F. X., Liu, H., Zijdenbos, A., Paus, T., Evans, A. C., & Rapoport, J. L. (1999) · Nature Neuroscience · doi:10.1038/13158 · Cited by 5,552
Self-citationA social neuroscience perspective on adolescent risk-taking
Steinberg, L. (2008) · Developmental Review · doi:10.1016/j.dr.2007.08.002 · Cited by 3,644
A self‐report measure of pubertal status: Reliability, validity and initial norms
Petersen, A. C., Crockett, L., Richards, M., & Boxer, A. (1988) · Journal of Youth and Adolescence · doi:10.1007/bf01537962 · Cited by 3,129
Cognitive and affective development in adolescence
Steinberg, L. (2005) · Trends in Cognitive Sciences · doi:10.1016/j.tics.2004.12.005 · Cited by 2,978
Synaptic density in human frontal cortex —Developmental changes and effects of aging
Peter R., H. (1979) · Brain Research · doi:10.1016/0006-8993(79)90349-4 · Cited by 2,645
Animal Physiology: Adaptation and Environment
Schmidt‐Nielsen, K. (1962) · Cited by 2,489
Flagged first, then by citations
Research works printed but not linked: 2
- Kaes, T. Die Grosshirnrinde des Menschen in ihren Massen und ihrem Fasergehalt (Fisher, Jena, 1907).
- Conel, J. Postnatal development of the human cerebral cortex: the cortex of the seventy- two- month infant. Vol. 8. (Harvard Univ. Press, Cambridge, Massachusetts, 1967).
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McGorry, P. D. (2010) · Neurotoxicity Research · doi:10.1007/s12640-010-9179-x · Cited by 42
RetractedMicroglial PCGF1 alleviates neuroinflammation associated depressive behavior in adolescent mice
Li, N., Du, J., Yang, Y., Zhao, T., Wu, D., Peng, F., Wang, D., Kong, L., Zhou, W., & Hao, A. (2024) · Molecular Psychiatry · doi:10.1038/s41380-024-02714-2 · Cited by 41
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Xiao, B., Wang, S., Liu, J., Meng, T., He, Y., & Luo, X. (2017) · Neuropsychiatric Disease and Treatment · doi:10.2147/ndt.s126678 · Cited by 41
Griffith, J. M., Young, J. F., & Hankin, B. L. (2019) · Emotion · doi:10.1037/emo0000682 · Cited by 41
Urbanicity, biological stress system functioning and mental health in adolescents
Evans, B. E., Huizink, A. C., Greaves‐Lord, K., Tulen, J. H. M., Roelofs, K., & van der Ende, J. (2020) · PLoS ONE · doi:10.1371/journal.pone.0228659 · Cited by 42
Bøen, R., Ferschmann, L., Vijayakumar, N., Øverbye, K., Fjell, A. M., Espeseth, T., & Tamnes, C. K. (2021) · Cortex · doi:10.1016/j.cortex.2021.01.018 · Cited by 41
Dvorsky, M. R., Breaux, R., Cusick, C. N., Fredrick, J. W., Green, C. D., Steinberg, A., Langberg, J. M., Sciberras, E., & Becker, S. P. (2021) · Research on Child and Adolescent Psychopathology · doi:10.1007/s10802-021-00857-2 · Cited by 41
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Lei, T., Liao, X., Chen, X., Zhao, T., Xu, Y., Xia, M., Zhang, J., Xia, Y., Sun, X., Wei, Y., et al. (2021) · Cerebral Cortex · doi:10.1093/cercor/bhab263 · Cited by 41
Swartz, J. R., & Monk, C. S. (2013) · Current topics in behavioral neurosciences · doi:10.1007/7854_2013_242 · Cited by 41
Bakshi, N. K., Pruitt, P. J., Radwan, J., Keshavan, M. S., Rajan, U., Zajac‐Benitez, C., & Diwadkar, V. A. (2011) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2011.01.002 · Cited by 41
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Bore, M. C., Liu, X., Huang, X., Kendrick, K. M., Zhou, B., Zhang, J., Klugah‐Brown, B., & Becker, B. (2024) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2024.105835 · Cited by 40
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Self-citationMoore, H. M. (2010) · Schizophrenia Bulletin · doi:10.1093/schbul/sbq106 · Cited by 40
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Botellero, V. L., Skranes, J. S., Bjuland, K. J., Haberg, A. K., Lydersen, S., Brubakk, A., Indredavik, M. S., & Martinussen, M. (2017) · BMC Pediatrics · doi:10.1186/s12887-017-0793-0 · Cited by 40
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Waters, L. E., Loton, D. J., Grace, D., Jacques-Hamilton, R., & Zyphur, M. J. (2019) · Frontiers in Psychology · doi:10.3389/fpsyg.2019.02273 · Cited by 40
Development and heritability of subcortical brain volumes at ages 9 and 12
Swagerman, S. C., Brouwer, R. M., de Geus, E. J. C., Pol, H. E. H., & Boomsma, D. I. (2014) · Genes Brain & Behavior · doi:10.1111/gbb.12182 · Cited by 40
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McGrath, J. J., & Richards, L. J. (2009) · Schizophrenia Bulletin · doi:10.1093/schbul/sbp004 · Cited by 40
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Bakken, T. E., Miller, J. A., Luo, R., Bernard, A., Bennett, J. L., Lee, C., Bertagnolli, D., Parikshak, N., Smith, K. A., Sunkin, S. M., et al. (2015) · Human Molecular Genetics · doi:10.1093/hmg/ddv166 · Cited by 40
Andersen, S. L., & Navalta, C. P. (2011) · Journal of Child Psychology and Psychiatry · doi:10.1111/j.1469-7610.2011.02376.x · Cited by 40
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Lü, M., Yang, C., Chu, T., & Wu, S. (2018) · Frontiers in Neurology · doi:10.3389/fneur.2018.00704 · Cited by 40
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Köck, P., Meyer, M., Elsner, J., Dürsteler, K. M., Vogel, M., & Walter, M. (2022) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2022.827658 · Cited by 41
Li, J., Zhang, C., Meng, Y., Yang, S., Xia, J., Chen, H., & Liao, W. (2024) · PLoS Biology · doi:10.1371/journal.pbio.3002647 · Cited by 39
Bernstein, H., Nussbaumer, M., Vasilevska, V., Dobrowolny, H., Nickl‐Jockschat, T., Guest, P. C., & Steiner, J. (2024) · Molecular Psychiatry · doi:10.1038/s41380-024-02861-6 · Cited by 42
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Prevost, M. L., Arenas‐Pinto, A., Melvin, D., Parrott, F., Foster, C., Ford, D., Evangeli, M., Winston, A., Sturgeon, K., Rowson, K., et al. (2018) · AIDS Care · doi:10.1080/09540121.2018.1441972 · Cited by 39
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Pile, V., & Lau, J. Y. F. (2019) · Behaviour Research and Therapy · doi:10.1016/j.brat.2019.103508 · Cited by 39
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Ferrett, H. L., Thomas, K. G. F., Tapert, S. F., Carey, P. D., Conradie, S., Cuzen, N. L., Stein, D. J., & Fein, G. (2014) · Metabolic Brain Disease · doi:10.1007/s11011-014-9495-6 · Cited by 39
Brand, S., Wilhelm, F. H., Kossowsky, J., Holsboer‐Trachsler, E., & Schneider, S. (2010) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2010.08.014 · Cited by 39
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Self-citationPauli‐Pott, U., & Becker, K. (2015) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2015.04.011 · Cited by 39
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Yao, X., Yang, C., Jia, X., Yu, Z., Wang, C., Zhao, J., Chen, Y., Xie, B., Zhuang, H., Sun, C., et al. (2024) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2024.04.005 · Cited by 38
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Zhang, Y., Zheng, J., Fan, X., Guo, X., Guo, W., Yang, G., Chen, H., Zhao, J., & Lv, L. (2015) · Schizophrenia Research · doi:10.1016/j.schres.2015.07.031 · Cited by 38
O’Connor, R. M., & Cryan, J. F. (2013) · Biological Psychiatry · doi:10.1016/j.biopsych.2013.10.022 · Cited by 38
Roy, A. V., Thai, M., Klimes‐Dougan, B., Schreiner, M. W., Mueller, B. A., Albott, C. S., Lim, K. O., Fiecas, M. J. A., Tye, S. J., & Cullen, K. R. (2020) · Journal of Psychopharmacology · doi:10.1177/0269881120928203 · Cited by 38
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Cattaneo, A., Suderman, M. J., Cattane, N., Mazzelli, M., Begni, V., Maj, C., D'Aprile, I., Pariante, C. M., Luoni, A., Berry, A., et al. (2020) · Neurobiology of Stress · doi:10.1016/j.ynstr.2020.100271 · Cited by 38
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Yu, Z., Han, Y., Hu, D., Chen, N., Zhang, Z., Chen, W., Xue, Y.-X., Meng, S., Lü, L., Zhang, W., et al. (2022) · Molecular Psychiatry · doi:10.1038/s41380-022-01495-w · Cited by 39
Effect of Growth Mindset on Mental Health Two Years Later: The Role of Smartphone Use
Lai, X., Nie, C., Huang, S., Li, Y., Xin, T., Zhang, C., & Wang, Y. (2022) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph19063355 · Cited by 38
Pathways for engaging in prosocial behavior in adolescence
Crone, E. A., Sweijen, S., Brinke, L. T., & van de Groep, S. (2022) · Advances in child development and behavior · doi:10.1016/bs.acdb.2022.03.003 · Cited by 38
Fang, Q., Cai, H., Jiang, P., Zhao, H., Song, Y., Zhao, W., Yu, Y., & Zhu, J. (2023) · Journal of Affective Disorders · doi:10.1016/j.jad.2023.01.051 · Cited by 38
Lawn, W., Trinci, K., Mokrysz, C., Borissova, A., Ofori, S., Petrilli, K., Bloomfield, M., Haniff, Z. R., Hall, D., Fernandez‐Vinson, N., et al. (2023) · Addiction · doi:10.1111/add.16154 · Cited by 38
Mood disorders in childhood and adolescence
Rocha, T. B. M., Zeni, C., Caetano, S. C., & Kieling, C. (2013) · Brazilian Journal of Psychiatry · doi:10.1590/1516-4446-2013-s106 · Cited by 38
Taylor, S. B., Taylor, A. R., & Koenig, J. I. (2012) · Neuroscience · doi:10.1016/j.neuroscience.2012.09.045 · Cited by 38
Simmons, J. G., Byrne, M. L., Schwartz, O., Whittle, S., Sheeber, L., Kaess, M., Youssef, G. J., & Allen, N. B. (2015) · Developmental Psychobiology · doi:10.1002/dev.21275 · Cited by 38
Sankar, T., Chakravarty, M. M., Jawa, N. A., Li, S. X., Giacobbe, P., Kennedy, S. H., Rizvi, S. J., Mayberg, H. S., Hamani, C., & Lozano, A. M. (2019) · Journal of Psychiatry and Neuroscience · doi:10.1503/jpn.180207 · Cited by 38
Growth and refinement of excitatory synapses in the human auditory cortex
Pundir, A. S., Singh, U. A., Ahuja, N., Makhija, S., Dikshit, P. C., Radotra, B. D., Kumar, P., Shankar, S. K., Mahadevan, A., Roy, T. S., et al. (2015) · Brain Structure and Function · doi:10.1007/s00429-015-1124-6 · Cited by 37
Tian, J., Yan, N., Hu, X., Tian, S., Wang, Y., Mackay, L. E., Luo, Y., Wang, Y., Wang, Y., Liu, Y., et al. (2025) · General Psychiatry · doi:10.1136/gpsych-2025-102278 · Cited by 37
Karl, T. (2013) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2013.00106 · Cited by 37
Enduring influence of pubertal stressors on behavioral response to hormones in female mice
Blaustein, J. D., & Ismail, N. (2013) · Hormones and Behavior · doi:10.1016/j.yhbeh.2013.01.015 · Cited by 37
Filatova, S., Marttila, R., Koivumaa-Honkanen, H. T., Nordström, T., Veijola, J. M., Maki, P. M., Khandaker, G. M., Isohanni, M. K., Jääskeläinen, E., Moilanen, K., et al. (2016) · Epidemiology and Psychiatric Sciences · doi:10.1017/s2045796016000123 · Cited by 37
Kozareva, D. A., O’Leary, O. F., Cryan, J. F., & Nolan, Y. M. (2017) · Hippocampus · doi:10.1002/hipo.22805 · Cited by 37
Li, M., Becker, B., Zheng, J., Zhang, Y., Chen, H., Liao, W., Duan, X., Liu, H., Zhao, J., & Chen, H. (2018) · Schizophrenia Bulletin · doi:10.1093/schbul/sby063 · Cited by 37
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Wang, Y., Lv, Z., & Zheng, Y. (2018) · Sensors · doi:10.3390/s18092826 · Cited by 37
Nabel, E. M., Garkun, Y., Koike, H., Sadahiro, M., Liang, A., Norman, K. J., Taccheri, G., Demars, M. P., Im, S., Caro, K., et al. (2020) · Nature Communications · doi:10.1038/s41467-020-17787-0 · Cited by 37
Winters, D. E., Pruitt, P. J., Fukui, S., Cyders, M. A., Pierce, B. J., Lay, K., & Damoiseaux, J. S. (2021) · Neuropsychologia · doi:10.1016/j.neuropsychologia.2021.107832 · Cited by 37
Lombardi, E., Traficante, D., Bettoni, R., Offredi, I., Vernice, M., & Sarti, D. (2021) · Behavioral Sciences · doi:10.3390/bs11070103 · Cited by 37
Gruber, R., Gauthier-Gagné, G., Voutou, D., Somerville, G., Saha, S., & Boursier, J. (2021) · Child and Adolescent Psychiatry and Mental Health · doi:10.1186/s13034-021-00399-x · Cited by 37
Štark, T., Martino, S. D., Drago, F., Wotjak, C. T., & Micale, V. (2021) · Pharmacological Research · doi:10.1016/j.phrs.2021.105938 · Cited by 37
Smartphone Addiction and Anxiety in Adolescents – A Cross-sectional Study
Kim, K., Yee, J., Chung, J. E., Kim, H. J., Han, J. M., Kim, J. H., Lee, K. E., & Gwak, H. S. (2021) · American Journal of Health Behavior · doi:10.5993/ajhb.45.5.9 · Cited by 37
Measuring Adolescent Chronic Stress: A Review of Established Biomarkers and Psychometric Instruments
Kokka, I., Chrousos, G. P., Darviri, C., & Bacopoulou, F. (2022) · Hormone Research in Paediatrics · doi:10.1159/000522387 · Cited by 37
Elite Sport is Not an Additional Source of Distress for Adolescents with High Stress Levels
Gerber, M., Holsboer‐Trachsler, E., Pühse, U., & Brand, S. (2011) · Perceptual and Motor Skills · doi:10.2466/02.05.10.pms.112.2.581-599 · Cited by 37
Genc, S., Malpas, C. B., Gülenç, A., Sciberras, E., Efron, D., Silk, T. J., & Seal, M. L. (2020) · Developmental Cognitive Neuroscience · doi:10.1016/j.dcn.2020.100853 · Cited by 37
Razavi, N., Jann, K., Koenig, T. W., Kottlow, M., Hauf, M., Strik, W. K., & Dierks, T. (2013) · PLoS ONE · doi:10.1371/journal.pone.0076604 · Cited by 36
Carrara‐Nascimento, P. F., Olive, M. F., & Camarini, R. (2012) · Developmental Psychobiology · doi:10.1002/dev.21089 · Cited by 36
DePoy, L. M., Allen, A. G., & Gourley, S. L. (2016) · Translational Psychiatry · doi:10.1038/tp.2016.150 · Cited by 36
Gerber, M., Endes, K., Brand, S., Herrmann, C., Colledge, F., Donath, L., Faude, O., Hanssen, H., Pühse, U., & Zahner, L. (2016) · Quality of Life Research · doi:10.1007/s11136-016-1472-6 · Cited by 36
Lovato, N., Short, M. A., Micic, G., Hiller, R. M., & Gradisar, M. (2017) · Nature and Science of Sleep · doi:10.2147/nss.s111521 · Cited by 36
Bachman, P., Niendam, T. A., Jalbrzikowkski, M., Park, C. Y., Daley, M., Cannon, T. D., & Bearden, C. E. (2012) · Journal of Abnormal Child Psychology · doi:10.1007/s10802-011-9592-5 · Cited by 33
Neurobiological correlates of resilience during childhood and adolescence – A systematic review
Zhang, L., Rakesh, D., Cropley, V., & Whittle, S. (2023) · Clinical Psychology Review · doi:10.1016/j.cpr.2023.102333 · Cited by 33
Metadata
- Authors
- Paus, T., Keshavan, M., & Giedd, J. N.
- Affiliations
- Montreal Neurological Institute and Hospital (CA)
- Beth Israel Deaconess Medical Center (US)
- National Institute of Mental Health (US)
- Corresponding author
- Paus, Tomáš
- Giedd, Jay N.
- Venue
- Nature Reviews Neuroscience
- Published
- 2008-11-12
- Volume
- 9
- Issue
- 12
- Pages
- 947-957
- ISSN
- 1471-003X (ISSN-L)
- 1471-0048
- PMC
- PMC2762785
- OpenAlex
- W2040073285
- Semantic Scholar
- 7c469b7f89043f4867b02938be67d786fc761827
- Cited by
- 3,123
- References
- 117
- Citations by year
- 2026: 198 · 2025: 230 · 2024: 213 · 2023: 242 · 2022: 230 · 2021: 262 · 2020: 251 · 2019: 162 · 2018: 202 · 2017: 147 · 2016: 179 · 2015: 186 · 2014: 148 · 2013: 149 · 2012: 100
- FWCI
- 5.35
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Nature reviews. Neuroscience (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institutes of Health
- National Institute of Mental Health (Z01MH002794)
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neural and Behavioral Psychology Studies
- Social Sciences › Psychology › Clinical Psychology › Child and Adolescent Psychosocial and Emotional Development
- Life Sciences › Neuroscience › Cognitive Neuroscience › Functional Brain Connectivity Studies
- Keywords
- adolescent brain development, mental illness, synaptic pruning, cortical maturation, white matter myelination, reward sensitivity
- MeSH terms
- Adolescent, Mental Disorders, Brain, Humans, Synaptic Transmission, Peer Group, Sex Characteristics, Age of Onset, Adolescent Development
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