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N6-methyladenosine (m6A) recruits and repels proteins to regulate mRNA homeostasis
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“The association of this complex with m6A appears to contrast with those SG complexes containing G3BP1 or 2, CAPRIN1 and USP10, which are repelled by RNA containing m6A”
From Interaction of tau with HNRNPA2B1 and N6-methyladenosine RNA mediates the progression of tauopathy (2021) · cites this paper as Edupuganti et al., 2017
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N6-methyladenosine-dependent regulation of messenger RNA stability
Wang, X., Lu, Z., Gomez, A., Hon, G. C., Yue, Y., Han, D., Fu, Y., Parisien, M., Dai, Q., Jia, G., et al. (2014) · Nature · doi:10.1038/nature12730 · Cited by 4,558
Self-citationComprehensive Analysis of mRNA Methylation Reveals Enrichment in 3′ UTRs and near Stop Codons
Meyer, K. D., Saletore, Y., Zumbo, P., Elemento, O., Mason, C. E., & Jaffrey, S. R. (2012) · Cell · doi:10.1016/j.cell.2012.05.003 · Cited by 4,223
N6-Methyladenosine in nuclear RNA is a major substrate of the obesity-associated FTO
Jia, G., Fu, Y., Zhao, X., Dai, Q., Zheng, G., Yang, Y., Yi, C., Lindahl, T., Pan, T., Yang, Y.-G., et al. (2011) · Nature Chemical Biology · doi:10.1038/nchembio.687 · Cited by 4,106
Self-citationALKBH5 Is a Mammalian RNA Demethylase that Impacts RNA Metabolism and Mouse Fertility
Zheng, G., Dahl, J. A., Niu, Y., Fedorcsak, P., Huang, C.-M., Li, C. J., Vågbø, C. B., Shi, Y., Wang, W.-L., Song, S.-H., et al. (2013) · Molecular Cell · doi:10.1016/j.molcel.2012.10.015 · Cited by 3,550
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Reading, writing and erasing mRNA methylation
Zaccara, S., Ries, R. J., & Jaffrey, S. R. (2019) · Nature Reviews Molecular Cell Biology · doi:10.1038/s41580-019-0168-5 · Cited by 2,597
G3BP1 is a tunable switch that triggers phase separation to assemble stress granules
Yang, P., Mathieu, C., Kolaitis, R.-M., Zhang, P., Messing, J., Yurtsever, U., Yang, Z., Wu, J., Li, Y., Pan, Q., et al. (2020) · Cell · doi:10.1016/j.cell.2020.03.046 · Cited by 1,249
The m6A epitranscriptome: transcriptome plasticity in brain development and function
Livneh, I., Moshitch-Moshkovitz, S., Amariglio, N., Rechavi, G., & Dominissini, D. (2020) · Nature Reviews Neuroscience · doi:10.1038/s41583-019-0244-z · Cited by 330
RNA m6A regulates transcription via DNA demethylation and chromatin accessibility
Deng, S., Zhang, J., Su, J., Zuo, Z., Zeng, L., Liu, K., Zheng, Y., Huang, X., Bai, R., Zhuang, L., et al. (2022) · Nature Genetics · doi:10.1038/s41588-022-01173-1 · Cited by 187
Interaction of tau with HNRNPA2B1 and N6-methyladenosine RNA mediates the progression of tauopathy
Jiang, L., Lin, W., Zhang, C., Ash, P. E. A., Verma, M., Kwan, J., van Vliet, E., Yang, Z., Cruz, A. L., Boudeau, S., et al. (2021) · Molecular Cell · doi:10.1016/j.molcel.2021.07.038 · Cited by 177
Profiling of m6A RNA modifications identified an age‐associated regulation of AGO 2 mRNA stability
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McMillan, M., Gomez, N., Hsieh, C., Bekier, M., Li, X., Miguez, R., Tank, E. M. H., & Barmada, S. J. (2023) · Molecular Cell · doi:10.1016/j.molcel.2022.12.019 · Cited by 112
Regué, L., Wang, W., Ji, F., Avruch, J., Wang, H., & Dai, N. (2023) · Diabetes · doi:10.2337/db21-1087 · Cited by 12
SUPREM: an engineered non-site-specific m6A RNA methyltransferase with highly improved efficiency
Ochiai, Y., Clifton, B. E., Le Coz, M., Terenzio, M., & Laurino, P. (2024) · Nucleic Acids Research · doi:10.1093/nar/gkae887 · Cited by 9
Metadata
- Authors
- Edupuganti, R. R., Geiger, S., Lindeboom, R. G. H., Shi, H., Hsu, P. J., Lu, Z., Wang, S.-Y., Baltissen, M. P. A., Jansen, P. W. T. C., Rossa, M., Müller, M., Stunnenberg, H. G., He, C., Carell, T., & Vermeulen, M.
- Venue
- Nature Structural & Molecular Biology
- Published
- 2017-09-04
- Volume
- 24
- Issue
- 10
- Pages
- 870-878
- ISSN
- 1545-9993
- 1545-9985
- PMC
- PMC5725193
- Cited by
- 556
- References
- 22
- Language
- en
- Licence
- www.springer.com/tdm (tdm)
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