The multifunctional RNA-binding protein hnRNP A1 is required for processing of miR-18a

The functions of animal microRNAs

Ambros, V. (2004) · Nature · doi:10.1038/nature02871 · Cited by 10,728

Identification of Novel Genes Coding for Small Expressed RNAs

Lagos-Quintana, M., Rauhut, R., Lendeckel, W., & Tuschl, T. (2001) · Science · doi:10.1126/science.1064921 · Cited by 4,956

A microRNA polycistron as a potential human oncogene

He, L., Thomson, J. M., Hemann, M. T., Hernando, E., Mu, D., Goodson, S. G., Powers, S., Cordon‐Cardo, C., Lowe, S. W., Hannon, G. J., et al. (2005) · Nature · doi:10.1038/nature03552 · Cited by 3,642

Nuclear Export of MicroRNA Precursors

Lund, E., Güttinger, S., Calado, Â., Dahlberg, J. E., & Kutay, U. (2003) · Science · doi:10.1126/science.1090599 · Cited by 2,705

MicroRNA maturation: stepwise processing and subcellular localization

Lee, Y., Jeon, K., Lee, J., Kim, S., & Kim, V. N. (2002) · The EMBO Journal · doi:10.1093/emboj/cdf476 · Cited by 2,572

The Drosha-DGCR8 complex in primary microRNA processingPreprint

Han, J., Lee, Y., Yeom, K.-H., Kim, Y. K., Jin, H., & Kim, V. N. (2004) · Genes & Development · doi:10.1101/gad.1262504 · Cited by 2,208

Identification of Mammalian microRNA Host Genes and Transcription Units

Rodriguez, A., Griffiths-Jones, S., Ashurst, J. L., & Bradley, A. (2004) · Genome Research · doi:10.1101/gr.2722704 · Cited by 2,128

Dicer functions in RNA interference and in synthesis of small RNA involved in developmental timing in C. elegans

Ketting, R. F., Fischer, S. E. J., Bernstein, E., Sijen, T., Hannon, G. J., & Plasterk, R. H. A. (2001) · Genes & Development · doi:10.1101/gad.927801 · Cited by 1,852

Molecular Basis for the Recognition of Primary microRNAs by the Drosha-DGCR8 Complex

Han, J., Lee, Y., Yeom, K., Nam, J., Heo, I., Rhee, J., Sohn, S. Y., Cho, Y., Zhang, B.-T., & Kim, V. N. (2006) · Cell · doi:10.1016/j.cell.2006.03.043 · Cited by 1,641

Messenger-RNA-binding proteins and the messages they carry

Dreyfuss, G., Kim, V. N., & Kataoka, N. (2002) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm760 · Cited by 1,457

CLIP Identifies Nova-Regulated RNA Networks in the Brain

Ule, J., Jensen, K. B., Ruggiu, M., Mele, A., Ule, A., & Darnell, R. B. (2003) · Science · doi:10.1126/science.1090095 · Cited by 1,120

Augmentation of tumor angiogenesis by a Myc-activated microRNA cluster

Dews, M., Homayouni, A., Yu, D., Murphy, D. A., Sevignani, C., Wentzel, E. A., Furth, E. E., Lee, W. M., Enders, G. H., Mendell, J. T., et al. (2006) · Nature Genetics · doi:10.1038/ng1855 · Cited by 1,049

Extensive post-transcriptional regulation of microRNAs and its implications for cancer

Thomson, J. M., Newman, M., Parker, J. S., Morin-Kensicki, E. M., Wright, T., & Hammond, S. M. (2006) · Genes & Development · doi:10.1101/gad.1444406 · Cited by 877

A Role for the RNase III Enzyme DCR-1 in RNA Interference and Germ Line Development in Caenorhabditis elegans

Knight, S. W., & Bass, B. (2001) · Science · doi:10.1126/science.1062039 · Cited by 875

Shuttling of pre-mRNA binding proteins between nucleus and cytoplasm

Piñol-Roma, S., & Dreyfuss, G. (1992) · Nature · doi:10.1038/355730a0 · Cited by 842

Identification and Characterization of a Novel Gene, C13orf25 , as a Target for 13q31-q32 Amplification in Malignant Lymphoma

Ota, A., Tagawa, H., Karnan, S., Tsuzuki, S., Karpas, A., Kira, S., Yoshida, Y., & Seto, M. (2004) · Cancer Research · doi:10.1158/0008-5472.can-03-3773 · Cited by 736

Regulation of alternative pre-mRNA splicing by hnRNP A1 and splicing factor SF2

Mayeda, A., & Krainer, A. R. (1992) · Cell · doi:10.1016/0092-8674(92)90477-t · Cited by 735

Molecular Evolution of a MicroRNA Cluster

Andrea Tanzer, A., & Stadler, P. F. (2004) · Journal of Molecular Biology · doi:10.1016/j.jmb.2004.03.065 · Cited by 650

Regulation of Alternative Splicing in Vivo by Overexpression of Antagonistic Splicing Factors

Cáceres, J. F., Stamm, S., Helfman, D. M., & Krainer, A. R. (1994) · Science · doi:10.1126/science.8085156 · Cited by 619

CLIP: A method for identifying protein–RNA interaction sites in living cells

Ule, J., Jensen, K. B., Mele, A., & Darnell, R. B. (2005) · Methods · doi:10.1016/j.ymeth.2005.07.018 · Cited by 614

Recognition and cleavage of primary microRNA precursors by the nuclear processing enzyme Drosha

Zeng, Y., Yi, R., & Cullen, B. R. (2004) · The EMBO Journal · doi:10.1038/sj.emboj.7600491 · Cited by 583

RNA binding specificity of hnRNP A1: significance of hnRNP A1 high‐affinity binding sites in pre‐mRNA splicing.

Burd, C. G., & Dreyfuss, G. (1994) · The EMBO Journal · doi:10.1002/j.1460-2075.1994.tb06369.x · Cited by 488

Post-transcriptional regulation of microRNA expression

Obernosterer, G., Leuschner, P. J. F., Alenius, M., & Martinez, J. (2006) · RNA · doi:10.1261/rna.2322506 · Cited by 474

Role of the Modular Domains of SR Proteins in Subnuclear Localization and Alternative Splicing Specificity

Cáceres, J. F., Misteli, T., Screaton, G. R., Spector, D. L., & Krainer, A. R. (1997) · The Journal of Cell Biology · doi:10.1083/jcb.138.2.225 · Cited by 417

A novel role for shuttling SR proteins in mRNA translationPreprint

Sanford, J. R., Gray, N. K., Beckmann, K., & Cáceres, J. F. (2004) · Genes & Development · doi:10.1101/gad.286404 · Cited by 407

Function of conserved domains of hnRNP A1 and other hnRNP A/B proteins.

Mayeda, A., Munroe, S. H., Cáceres, J. F., & Krainer, A. R. (1994) · The EMBO Journal · doi:10.1002/j.1460-2075.1994.tb06883.x · Cited by 329

Regulated tissue-specific expression of antagonistic pre-mRNA splicing factors.

Hanamura, A., Cáceres, J. F., Mayeda, A., Franza, B. R., & Krainer, A. R. (1998) · PubMed Central · Cited by 329

hnRNP A1 Relocalization to the Stress Granules Reflects a Role in the Stress Response

Guil, S., Long, J. C., & Cáceres, J. F. (2006) · Molecular and Cellular Biology · doi:10.1128/mcb.00224-06 · Cited by 318

A Role for the M9 Transport Signal of hnRNP A1 in mRNA Nuclear Export

Izaurralde, E., Jarmołowski, A., Beisel, C., Mattaj, I. W., Dreyfuss, G., & Fischer, U. (1997) · The Journal of Cell Biology · doi:10.1083/jcb.137.1.27 · Cited by 269

hnRNP A/B proteins are required for inhibition of HIV‐1 pre‐mRNA splicing

Caputi, M., Mayeda, A., Krainer, A. R., & Zahler, A. M. (1999) · The EMBO Journal · doi:10.1093/emboj/18.14.4060 · Cited by 258

Intronic Binding Sites for hnRNP A/B and hnRNP F/H Proteins Stimulate Pre-mRNA Splicing

Martínez-Contreras, R. D., Fisette, J., Nasim, F., Madden, R., Cordeau, M., & Chabot, B. (2006) · PLoS Biology · doi:10.1371/journal.pbio.0040021 · Cited by 226

The A1 and A1B proteins of heterogeneous nuclear ribonucleoparticles modulate 5' splice site selection in vivo.

Yang, X., Bani, M. R., Lu, S. J., Rowan, S., Ben‐David, Y., & Chabot, B. (1994) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.91.15.6924 · Cited by 191

A Combinatorial Code for Splicing Silencing: UAGG and GGGG Motifs

Han, K., Yeo, G. W.-M., An, P., Burge, C. B., & Grabowski, P. J. (2005) · PLoS Biology · doi:10.1371/journal.pbio.0030158 · Cited by 171

Regulation of heterogenous nuclear ribonucleoprotein A1 transport by phosphorylation in cells stressed by osmotic shock

Allemand, E., Guil, S., Myers, M. P., Moscat, J., Cáceres, J. F., & Krainer, A. R. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0409889102 · Cited by 161

Heterogeneous Nuclear Ribonucleoprotein A1 Is a Novel Internal Ribosome Entry Site trans-Acting Factor That Modulates Alternative Initiation of Translation of the Fibroblast Growth Factor 2 mRNA

Bonnal, S., Pileur, F., Orsini, C., Parker, F., Pujol, F., Prats, A., & Vagner, S. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m411492200 · Cited by 156

Roles of hnRNP A1, SR Proteins, and p68 Helicase in c-H-ras Alternative Splicing Regulation

Guil, S., Gattoni, R. C., Carrascal, M., Abián, J., Stévenin, J., & Bach‐Elias, M. (2003) · Molecular and Cellular Biology · doi:10.1128/mcb.23.8.2927-2941.2003 · Cited by 126

Modulation of AUUUA Response Element Binding by Heterogeneous Nuclear Ribonucleoprotein A1 in Human T Lymphocytes

Hamilton, B. J., Burns, C. M., Nichols, R. C., & Rigby, W. F. C. (1997) · Journal of Biological Chemistry · doi:10.1074/jbc.272.45.28732 · Cited by 109

Heterogeneous Ribonucleoprotein A1 Is Part of an Exon-specific Splice-silencing Complex Controlled by Oncogenic Signaling Pathways

Matter, N., Marx, M., Weg‐Remers, S., Ponta, H., Herrlich, P. A., & König, H. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.m004692200 · Cited by 100

Roles for SR Proteins and hnRNP A1 in the Regulation of c -src Exon N1

Rooke, N., Markovtsov, V. V., Çağavi, E., & Black, D. L. (2003) · Molecular and Cellular Biology · doi:10.1128/mcb.23.6.1874-1884.2003 · Cited by 92

Identification of an hnRNP A1-Dependent Splicing Silencer in the Human Papillomavirus Type 16 L1 Coding Region That Prevents Premature Expression of the Late L1 Gene

Zhao, X., Rush, M., & Schwartz, S. (2004) · Journal of Virology · doi:10.1128/jvi.78.20.10888-10905.2004 · Cited by 79

Decrease in hnRNP A/B expression during erythropoiesis mediates a pre‐mRNA splicing switch

Hou, V., Lersch, R., Gee, S. L., Ponthier, J. L., Lo, A., Wu, M., Turck, C. W., Koury, M. J., Krainer, A. R., Mayeda, A., et al. (2002) · The EMBO Journal · doi:10.1093/emboj/cdf625 · Cited by 69

Alternative Splicing of the Adenylyl Cyclase Stimulatory G-protein Gαs Is Regulated by SF2/ASF and Heterogeneous Nuclear Ribonucleoprotein A1 (hnRNPA1) and Involves the Use of an Unusual TG 3′-Splice Site

Pollard, A. J., Krainer, A. R., Robson, S. C., & Europe‐Finner, G. N. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m109046200 · Cited by 59

Regulation of microRNA biogenesis

Ha, M., & Kim, V. N. (2014) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm3838 · Cited by 5,462

Biogenesis of small RNAs in animals

Kim, V. N., Han, J., & Siomi, M. C. (2009) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm2632 · Cited by 2,814

Transcriptome-wide Identification of RNA-Binding Protein and MicroRNA Target Sites by PAR-CLIP

Hafner, M., Landthaler, M., Burger, L., Khorshid, M., Hausser, J., Berninger, P., Rothballer, A., Ascano, M., Jungkamp, A.-C., Munschauer, M., et al. (2010) · Cell · doi:10.1016/j.cell.2010.03.009 · Cited by 2,873

Many roads to maturity: microRNA biogenesis pathways and their regulation

Winter, J. J., Jung, S., Keller, S., Gregory, R. I., & Diederichs, S. (2009) · Nature Cell Biology · doi:10.1038/ncb0309-228 · Cited by 2,765

MicroRNA biogenesis pathways in cancer

Lin, S., & Gregory, R. I. (2015) · Nature reviews. Cancer · doi:10.1038/nrc3932 · Cited by 2,169

Stimulation of pri-miR-18a Processing by hnRNP A1

Michlewski, G., Guil, S., & Cáceres, J. F. (2010) · Advances in experimental medicine and biology · doi:10.1007/978-1-4419-7823-3_3 · Cited by 48

Structural basis for the recognition of pri‐mir‐18a by hnRNP A1

Ding, L., & Ma, J. (2009) · The FASEB Journal · doi:10.1096/fasebj.23.1_supplement.844.3

Structural basis for terminal loop recognition and stimulation of pri-miRNA-18a processing by hnRNP A1

Kooshapur, H., Choudhury, N. R., Simon, B., Mühlbauer, M. E., Jussupow, A., Fernández, N., Jones, A. N., Dallmann, A., Gabel, F., Camilloni, C., et al. (2018) · Nature Communications · doi:10.1038/s41467-018-04871-9 · Cited by 113

Posttranscriptional Regulation of miRNAs Harboring Conserved Terminal Loops

Michlewski, G., Guil, S., Semple, C. A. M., & Cáceres, J. F. (2008) · Molecular Cell · doi:10.1016/j.molcel.2008.10.013 · Cited by 350

Not miR-ly a splicing factor: hnRNP A1 succumbs to microRNA temptation

Nielsen, A. F., Leuschner, P. J. F., & Martı̂nez, J. (2007) · Nature Structural & Molecular Biology · doi:10.1038/nsmb0707-572 · Cited by 5