Single-defect spectroscopy in the shortwave infrared
Open accessAbstract
Chemical defects that fluoresce in the shortwave infrared open exciting opportunities in deep-penetration bioimaging, chemically specific sensing, and quantum technologies. However, the atomic size of defects and the high noise of infrared detectors have posed significant challenges to the studies of these unique emitters. Here we demonstrate high throughput single-defect spectroscopy in the shortwave infrared capable of quantitatively and spectrally resolving chemical defects at the single defect level. By cooling an InGaAs detector array down to −190 °C and implementing a nondestructive readout scheme, we are able to capture low light fluorescent events in the shortwave infrared with a signal-to-noise ratio improved by more than three orders-of-magnitude. As a demonstration, we show it is possible to resolve individual chemical defects in carbon nanotube semiconductors, simultaneously collecting a full spectrum for each defect within the entire field of view at the single defect limit.
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OCC fluorescence is molecularly specific and extremely sensitive to the local chemical environment of the atomic defect sites.
“OCC fluorescence, on the other hand, is molecularly specific and extremely sensitive to the local chemical environment of the atomic defect sites32,41.”
From Detection of ovarian cancer via the spectral fingerprinting of quantum-defect-modified carbon nanotubes in serum by machine learning (2022) · cites this paper as [41]
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- Authors
- Wu, X., Kim, M., Qu, H., & Wang, Y.
- Affiliations
- University of Maryland, College Park (US)
- Corresponding author
- Wang, YuHuang
- Venue
- Nature Communications
- Published
- 2019-06-17
- Volume
- 10
- Issue
- 1
- Pages
- 2672-2672
- ISSN
- 2041-1723 (ISSN-L)
- PMC
- PMC6572808
- OpenAlex
- W2949192847
- Cited by
- 58
- References
- 36
- Citations by year
- 2026: 5 · 2025: 6 · 2024: 3 · 2023: 4 · 2022: 12 · 2021: 15 · 2020: 7 · 2019: 6
- FWCI
- 3.59
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Locations
- Nature Communications (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- RePEc: Research Papers in Economics (submittedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion)
- OSTI OAI (U.S. Department of Energy Office of Scientific and Technical Information) (submittedVersion)
- Funders
- U.S. Department of Health & Human Services | NIH | National Institute of General Medical Sciences (R01GM114167)
- U.S. Department of Energy (DE-SC0019112)
- National Science Foundation (CHE-1904488)
- Topics
- Physical Sciences › Engineering › Electrical and Electronic Engineering › Advanced Semiconductor Detectors and Materials
- Physical Sciences › Chemistry › Spectroscopy › Spectroscopy and Laser Applications
- Physical Sciences › Engineering › Aerospace Engineering › Infrared Target Detection Methodologies
- Keywords
- shortwave infrared, infrared fluorescence, chemical defects, nondestructive readout, signal-to-noise ratio, defect quantification, infrared detection
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