The gut microbiome as a modulator of healthy ageing

The Hallmarks of Aging

López-Otín, C., Blasco, M. A., Partridge, L., Serrano, M., & Kroemer, G. (2013) · Cell · doi:10.1016/j.cell.2013.05.039 · Cited by 14,982

The Microbiota-Gut-Brain Axis

Cryan, J. F., O'Riordan, K. J., Cowan, C. S. M., Sandhu, K. V., Bastiaanssen, T. F. S., Boehme, M., Codagnone, M. G., Cussotto, S., Fulling, C., Golubeva, A. V., et al. (2019) · Physiological Reviews · doi:10.1152/physrev.00018.2018 · Cited by 5,286

Faecalibacterium prausnitzii is an anti-inflammatory commensal bacterium identified by gut microbiota analysis of Crohn disease patients

Sokol, H., Pigneur, B., Watterlot, L., Lakhdari, O., Bermúdez-Humarán, L. G., Gratadoux, J.-J., Blugeon, S., Bridonneau, C., Furet, J.-P., Corthier, G., et al. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0804812105 · Cited by 4,413

Evolution of mammals and their gut microbes

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The Human Intestinal Microbiome in Health and Disease

Lynch, S. V., & Pedersen, O. (2016) · New England Journal of Medicine · doi:10.1056/nejmra1600266 · Cited by 3,637

Gut microbiota composition correlates with diet and health in the elderly

Claesson, M. J., Jeffery, I. B., Conde, S., Power, S. E., O’Connor, E. M., Cusack, S., Harris, H. M. B., Coakley, M., Lakshminarayanan, B., O’Sullivan, O., et al. (2012) · Nature · doi:10.1038/nature11319 · Cited by 3,314

Supplementation with Akkermansia muciniphila in overweight and obese human volunteers: A proof-of-concept exploratory study

Depommier, C., Everard, A., Druart, C., Plovier, H., Van Hul, M., Vieira-Silva, S., Falony, G., Raes, J., Maiter, D., Delzenne, N. M., et al. (2019) · Nature Medicine · doi:10.1038/s41591-019-0495-2 · Cited by 2,357

The role of the gut microbiota in nutrition and health

Flint, H. J., Scott, K. P., Louis, P., & Duncan, S. H. (2012) · Nature Reviews Gastroenterology & Hepatology · doi:10.1038/nrgastro.2012.156 · Cited by 2,283

Human gut microbes impact host serum metabolome and insulin sensitivity

Pedersen, H. K., Gudmundsdottir, V., Nielsen, H. B., Hyotylainen, T., Nielsen, T., Jensen, B. A. H., Forslund, K., Hildebrand, F., Prifti, E., Falony, G., et al. (2016) · Nature · doi:10.1038/nature18646 · Cited by 2,116

Association of Gut Microbiome and Dipeptidyl Peptidase 4 in Immune-Mediated Inflammatory Bowel Disease: A Rapid Literature Review

Gomes, S. F., Valois, A., Estevinho, M. M., Santiago, M., & Magro, F. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms252312852 · Cited by 11

Aging and sex differences in salt sensitivity of blood pressure

Demirci, M., Afolabi, J., & Kirabo, A. (2025) · Clinical Science · doi:10.1042/cs20240788 · Cited by 11

Effects of Blueberry Consumption on Fecal Microbiome Composition and Circulating Metabolites, Lipids, and Lipoproteins in a Randomized Controlled Trial of Older Adults with Overweight or Obesity: The BEACTIVE Trial

Starr, K. N. P., Connelly, M. A., Wallis, J., North, R., Zhang, Q., Song, K., González-Delgado, J. M., Brochu, H. N., Icenhour, C. R., Iyer, L. K., et al. (2025) · Nutrients · doi:10.3390/nu17071200 · Cited by 11

In vitro wound healing effects of postbiotics derived from the gut microbiota of long‐lived blind mole rats, a model of healthy ageing

Demirhan, H. K., Aksoy, Z. B., Karaca, B., Kankılıç, T., Akçalı, K. C., & Kıran, F. (2025) · Wound Repair and Regeneration · doi:10.1111/wrr.70023 · Cited by 11

Biological properties, synthetic pathways and anti-aging mechanisms of nicotinamide mononucleotide (NMN): Research progress and challenges

Wang, E., Wang, Y., Zhang, Z., Jiang, Y., & Zhao, C. (2025) · Biogerontology · doi:10.1007/s10522-025-10270-7 · Cited by 11

Cloudberry-derived nanovesicles as stable oral drug delivery systems: gastrointestinal stability and age-related biodistribution in mice

Shanthi, K. B., Pratiwi, F. W., Naillat, F., Mammadova, R., Sarpola, M., Wu, S., Suokas, M., Jokipii‐Lukkari, S., Kaisto, S., Samoylenko, A., et al. (2025) · Nanoscale · doi:10.1039/d4nr04694c · Cited by 11

Qula-derived Limosilactobacillus fermentum TD-3 and Lactococcus lactis MQ1-1 alleviate aging-related intestinal barrier dysfunction via microbiota–short-chain fatty acid–AMPK/MLCK–tight junction axis

Liu, X., Guan, K., Liu, C., Sun, Y., Ma, Y., Mao, K., Li, Q., Wang, R., & Lu, W. (2025) · Journal of Dairy Science · doi:10.3168/jds.2025-26740 · Cited by 11

Aging-dependent skin microbiome alterations across body sites in a United Kingdom cohort

Swaney, M. H., Newman, D. J., Mao, J., Hilton, A. C., Worthington, T., & Li, M. (2025) · Frontiers in Aging · doi:10.3389/fragi.2025.1644012 · Cited by 11

Gut microbiome features associated with Bifidobacterium colonization predict personalized probiotic persistence patterns

Goswami, S., Ansari, A., Saraf, C., O’Toole, P. W., Shanahan, F., Ahuja, V., & Ghosh, T. S. (2026) · Nature Communications · doi:10.1038/s41467-026-72289-9 · Cited by 11

Aging, Cutaneous Burn Injury and Multi-Organ Complications: The Role of the Gut

McMahan, R. H., Boe, D. M., Walrath, T., Idrovo, J., & Kovacs, E. J. (2022) · Advances in Geriatric Medicine and Research · doi:10.20900/agmr20220004 · Cited by 11

Short-chain fatty acid production in accessible and inaccessible body pools as assessed by novel stable tracer pulse approach is reduced by aging independent of presence of COPD

Kirschner, S. K., Ghane, P., Park, J. K., Simbo, S. Y., Ivanov, I. V., Braga-Neto, U., Have, G. A. M. T., Thaden, J. J., ENGELEN, M. P. K. J., & Deutz, N. E. P. (2023) · Metabolism · doi:10.1016/j.metabol.2023.155399 · Cited by 11

Guidelines for microbiome studies in renal physiology

Muralitharan, R. R., Snelson, M., Méric, G., Coughlan, M. T., & Marques, F. Z. (2023) · American Journal of Physiology-Renal Physiology · doi:10.1152/ajprenal.00072.2023 · Cited by 11

Evidence that the loss of colonic anti-microbial peptides may promote dysbiotic Gram-negative inflammaging-associated bacteria in aging mice

Forsyth, C. B., Shaikh, M. W., Engen, P. A., Preuss, F., Naqib, A. D., Palmen, B. A., Green, S. J., Zhang, L., Bogin, Z. R., Lawrence, K. M., et al. (2024) · Frontiers in Aging · doi:10.3389/fragi.2024.1352299 · Cited by 11

Prognostic Significance of the Relative Load of KPC-Producing Klebsiella pneumoniae within the Intestinal Microbiota in a Prospective Cohort of Colonized Patients

Pérez‐Nadales, E., Natera, A. M., Recio, M., Guzmán-Puche, J., Marín-Sanz, J. A., Martín-Pérez, C., Cano, Á., Castón, J. J., Elías-López, C., Machuca, I., et al. (2022) · Microbiology Spectrum · doi:10.1128/spectrum.02728-21 · Cited by 11

What Can the Gut Microbiota of Animals Teach Us about the Relationship between Nutrition and Burden of Lifestyle Diseases?

Mafra, D., Borges, N. A., Baptista, B. G., Martins, L. F., Borland, G., Shiels, P. G., & Stenvinkel, P. (2024) · Nutrients · doi:10.3390/nu16111789 · Cited by 11

Microbiota from young mice counteracts susceptibility to age-related gout through modulating butyric acid levels in aged mice

Song, N., Gao, H., Li, J., Liu, Y., Wang, M., Ma, Z., Zhang, N., & Zhang, W. (2024) · eLife · doi:10.7554/elife.98714.4 · Cited by 10

The Potential Role of Microbiota in Age-Related Cognitive Decline: A Narrative Review of the Underlying Molecular Mechanisms

Olejnik, P., Golenia, A., & Małyszko, J. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms26041590 · Cited by 10

Modulation of oral vaccine efficacy by the gut microbiota

Hou, Y., Li, J., & Wu, Y. (2025) · npj Vaccines · doi:10.1038/s41541-025-01240-8 · Cited by 11

The microbiome is associated with obesity-related metabolome signature in the process of aging

Binyamin, D., Turjeman, S., Asulin, N., Schweitzer, R., & Koren, O. (2025) · npj Biofilms and Microbiomes · doi:10.1038/s41522-025-00811-w · Cited by 10

Gut Microbiota and Nutrition in Nursing Homes: Challenges and Translational Approaches for Healthy Aging

Jiménez-Arroyo, C., Molinero, N., & Moreno-Arribas, M. V. (2025) · Advances in Nutrition · doi:10.1016/j.advnut.2025.100520 · Cited by 10

Polypharmacy is associated with altered gut microbiota diversity in older post-stroke inpatients

Matsumoto, A., Yoshimura, Y., Wakabayashi, H., Nagano, F., Shimazu, S., Kido, Y., Shiraishi, A., Hamada, T., Yoneda, K., & Maeda, K. (2025) · Clinical Nutrition ESPEN · doi:10.1016/j.clnesp.2025.10.015 · Cited by 10

Aging in women – The microbiome perspective

Ferrando, M. L., Busonero, F., Crobu, F., & Sanna, S. (2025) · Ageing Research Reviews · doi:10.1016/j.arr.2025.102950 · Cited by 10

Sex-Specific Diet–Microbiota Interactions in Ageing: Implications for Healthy Longevity

Hernández-Acosta, J., Tovar, A. R., & Torres, N. (2025) · Nutrients · doi:10.3390/nu17243833 · Cited by 10

Gut microbiota responses to bariatric surgery are associated with metabolic outcomes and type 2 diabetes remission

Olsson, L. M., Borgeraas, H., Chakaroun, R., Hofsø, D., Hertel, J. K., Dwibedi, C. K., Mitteregger, M., Holst, J. J., Tremaroli, V., Hjelmesaeth, J. S., et al. (2026) · Nature Metabolism · doi:10.1038/s42255-026-01525-9 · Cited by 10

Early Oral Administration of Ginseng Stem-Leaf Saponins Enhances the Peyer’s Patch-Dependent Maternal IgA Antibody Response to a PEDV Inactivated Vaccine in Mice, with Gut Microbiota Involvement

Su, F., Li, J., Xue, Y., Yu, B., Ye, S., Xu, L., Fu, Y., & Yuan, X. (2023) · Vaccines · doi:10.3390/vaccines11040830 · Cited by 10

A Novel Prebiotic Fibre Blend Supports the Gastrointestinal Health of Senior Dogs

Bon, M. L., Carvell-Miller, L. J., Marshall-Jones, Z. V., Watson, P., & Amos, G. C. A. (2023) · Animals · doi:10.3390/ani13203291 · Cited by 10

Short-term periodic restricted feeding elicits metabolome-microbiome signatures with sex dimorphic persistence in primate intervention

Yanai, H., Park, B., Koh, H., Jang, H. J., Vaughan, K. L., Tanaka-Yano, M., Aon, M. A., Blanton, M. B., Messaoudi, I., Díaz‐Ruiz, A., et al. (2024) · Nature Communications · doi:10.1038/s41467-024-45359-z · Cited by 10

Gut Microbiome Dysbiosis in Patients with Pemphigus and Correlation with Pathogenic Autoantibodies

Li, S., Wu, Q., Fan, Y., Guo, F., Hu, X., & Zuo, Y. (2024) · Biomolecules · doi:10.3390/biom14070880 · Cited by 10

Integrative metagenomics and metabolomics reveal age-associated gut microbiota and metabolite alterations in a hamster model of COVID-19

Rodrigues, P. B., Rodovalho, V. D. R., Sencio, V., Benech, N., Creskey, M., Angulo, F. S., Delval, L., Robil, C., Gosset, P., Machelart, A., et al. (2025) · Gut Microbes · doi:10.1080/19490976.2025.2486511 · Cited by 10

Perspectives on using bacteriophages in biogerontology research and interventions

Gierlicka, I., Rattan, S. I. S., & Wnuk, M. (2022) · Chemico-Biological Interactions · doi:10.1016/j.cbi.2022.110098 · Cited by 10

Older adults and healthcare professionals have limited awareness of the link between the Mediterranean diet and the gut microbiome for healthy aging

O’Mahony, L., O’Shea, E., O’Connor, E. M., Tierney, A. C., Harkin, M., Harrington, J. M., Kennelly, S., Arendt, E. K., O’Toole, P. W., & Timmons, S. (2023) · Frontiers in Nutrition · doi:10.3389/fnut.2023.1104238 · Cited by 10

Gut microbial genetic variation modulates host lifespan, sleep, and motor performance

Li, Y., Xu, S., Wang, L., Shi, H., Fang, Z., Fang, Z., Hu, Y., Jin, J., Du, Y.-R., Deng, M., et al. (2023) · The ISME Journal · doi:10.1038/s41396-023-01478-x · Cited by 10

Treating Leaky Syndrome in the Over 65s: Progress and Challenges

Jain, S., Marotta, F., Haghshenas, L., & Yadav, H. (2023) · Clinical Interventions in Aging · doi:10.2147/cia.s409801 · Cited by 10

Network modeling and topology of aging

Li, F., Yang, D., Wu, S., Xue, C., Sang, M., Liu, X., Che, J., Wu, J., Gragnoli, C., Griffin, C. H., et al. (2024) · Physics Reports · doi:10.1016/j.physrep.2024.10.006 · Cited by 9

Ampelopsis grossedentata tea polysaccharide alleviates D-galactose-induced aging in mice and regulates gut microbiota

Pan, J., Chen, F., Yu, L., Hong, K., Ye, Z., Zhang, Q., Zhang, C., Zhao, J., Zhai, Q., & Tian, F. (2024) · Food Bioscience · doi:10.1016/j.fbio.2024.105635 · Cited by 9

Human Milk Oligosaccharides Modulating Inflammation in Infants, Adults, and Older Individuals—From Concepts to Applications

Häsler, R., Mikš‐Krajnik, M., Bajic, D., Soyyılmaz, B., Bendik, I., van Buul, V. J., Steinert, R. E., & Rehman, A. (2025) · Advances in Nutrition · doi:10.1016/j.advnut.2025.100433 · Cited by 9

Alternative splicing in aging and aging-related diseases: From pathogenesis to therapy

Han, M., Han, P., Wang, Z., Kong, L., Xu, Q., Liu, Q., & Sun, Y. (2025) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2025.108887 · Cited by 9

Genesis, Health Benefits, and Future Perspectives of Probiotics: Exploring Endogenous and Exogenous Classes, Innovations, and Research Gaps

Mafe, A. N., Obumneme, O. S., Edo, G. I., Akpoghelie, P. O., Gaaz, T. S., Yousif, E., Isoje, E. F., Igbuku, U. A., Ismael, S. A., Essaghah, A. E. A., et al. (2025) · Probiotics and Antimicrobial Proteins · doi:10.1007/s12602-025-10756-3 · Cited by 9

Impact of probiotic, prebiotic, and synbiotic supplementation on the gut microbiome in older adults with sarcopenia, obesity, and sarcopenic obesity

Gandham, A., Prokopidis, K., Glavas, C., Scott, D., & Lorentzon, M. (2026) · Osteoporosis International · doi:10.1007/s00198-025-07801-w · Cited by 9

Advances in fucoidan extraction and structure-bioactivity relationships

Mensah, E. O., Sommer‐Knudsen, J., Thaysen‐Andersen, M., & Sunna, A. (2026) · Carbohydrate Polymers · doi:10.1016/j.carbpol.2026.125134 · Cited by 9

Talk to Me—Interplay between Mitochondria and Microbiota in Aging

Endres, K., & Friedland, K. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms241310818 · Cited by 9

The aging tumor metabolic microenvironment

Pilley, S. E., Esparza, E., & Mullen, P. J. (2023) · Current Opinion in Biotechnology · doi:10.1016/j.copbio.2023.102995 · Cited by 9

The gut microbiome as a modulator of arterial function and age-related arterial dysfunction

Longtine, A. G., Greenberg, N., de Quirós, Y. B., & Brunt, V. E. (2024) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00764.2023 · Cited by 9

Immune aging in annual killifish

Morabito, G., Ryabova, A., & Valenzano, D. R. (2024) · Immunity & Ageing · doi:10.1186/s12979-024-00418-3 · Cited by 9

Insights into Gut Microbiome Composition in Hidradenitis Suppurativa: A Comprehensive Examination of Dietary Habits and Environmental Influences

Lelonek, E., & Szepietowski, J. C. (2024) · Nutrients · doi:10.3390/nu16111776 · Cited by 9

Understanding Aging through the Lense of Gut Microbiome

Ira, R., Adwani, J., Krishnan, A. O., Subramanian, G., Yadav, S., Shukla, S., Rao, S., & Prakash, T. (2024) · Exploratory Research and Hypothesis in Medicine · doi:10.14218/erhm.2024.00008 · Cited by 9

The role of gut-derived short-chain fatty acids in Parkinson's disease

Saadh, M. J., Mustafa, A. N., Mustafa, M. A., Renuka Jyothi, S., Dabis, H. K., Prasad, G. V. S., Mohammad, I. J., Adnan, A., & Idan, A. H. (2024) · Neurogenetics · doi:10.1007/s10048-024-00779-3 · Cited by 9

Identification of age-associated microbial changes via long-read 16S sequencing

Toh, K. Y., Toh, T. S., Chua, K. P., Rajakumar, P. D., Lee, J. W. J., & Chong, C. W. (2024) · Gut Pathogens · doi:10.1186/s13099-024-00650-8 · Cited by 9

Rejuvenation Strategy for Inducing and Enhancing Autoimmune Response to Eliminate Senescent Cells

Wang, X., Zhang, C., Su, J., Ren, S., Wang, X., Zhang, Y., Yuan, Z., He, X., Wu, X., Li, M., et al. (2025) · Aging and disease · doi:10.14336/ad.2024.0579 · Cited by 8

Microbiome: A Key Regulator of Body-Brain Interactions

O’Riordan, K. J., Aburto, M. R., Nagpal, J. K., Clarke, G. A., & Cryan, J. F. (2025) · Advances in experimental medicine and biology · doi:10.1007/978-3-031-89525-8_6 · Cited by 9

Mitigating natural aging in Drosophila melanogaster with Tremella fuciformis polysaccharides

Qiang, Y., Min, Y., Li, W., Chen, D., Zhang, S., Chen, H., Guo, Z., ShaoXiao, Z., & Zheng, B. (2025) · Food Bioscience · doi:10.1016/j.fbio.2025.107145 · Cited by 8

The Effects of a Multidomain Lifestyle Intervention on Brain Function and Its Relation With Immunometabolic Markers and Intestinal Health in Older Adults at Risk of Cognitive Decline: Study Design and Baseline Characteristics of the HELI Randomized Controlled Trial

van Loenen, M. R., Remie, L. B., van Trijp, M. P. H., Jansen, M. G., Marques, J. P., Claassen, J. A. H. R., van de Rest, O., Vermeiren, Y., Smidt, N., Sikkes, S. A. M., et al. (2025) · JMIR Research Protocols · doi:10.2196/69814 · Cited by 8

Iron-saturated bovine lactoferrin preserves microbiota diversity and healthy ageing-associated taxa in an in vitro colon model of elderly gut microbiota (Iron-saturated bovine lactoferrin impact on elderly gut microbiota)

Ruiz‐Rico, M., Ye, H., O’Callaghan, T. F., O’Toole, P. W., & McCarthy, E. K. (2025) · PLoS ONE · doi:10.1371/journal.pone.0332631 · Cited by 8

The Interplay of Aging and Cancer: Mechanisms, Implications, and Therapeutic Strategies

Wang, L., Luo, Y., Chen, X., Wang, Y., & Zhang, Y. (2025) · MedComm – Oncology · doi:10.1002/mog2.70041 · Cited by 8

Microbiota shape the colon epithelium controlling inter-crypt absorptive goblet cells via butyrate–GP R109A signalling

Nirello, V. D., Araújo, N. V. P., de Assis, H. C., Moreno‐Gonzalez, M., Ruiz, P. S. B., Castro, P. R., Shealy, N. G., Shelton, C. D., Fernandes, M. F., de Oliveira, S., et al. (2025) · Gut Microbes · doi:10.1080/19490976.2025.2573045 · Cited by 8

Odoribacter splanchnicus rescues aging-related intestinal P-glycoprotein damage via GDP-L-fucose secretion

Cui, C., Fang, L., Li, L., Lai, X., Zhang, R., Zhang, Q., Miao, R., Hu, G., Zhang, M., Sia, J. E. V., et al. (2025) · Nature Communications · doi:10.1038/s41467-025-65692-1 · Cited by 8

Links Between Autophagy and Healthy Aging

Ebata, H., & Hansen, M. (2026) · Journal of Molecular Biology · doi:10.1016/j.jmb.2026.169656 · Cited by 10

Human Milk Microbiota and Oligosaccharides: Origin, Structure, Impact Factors, and Benefits for Infant Health

Wei, X., Yu, L., Zhao, J., Zhai, Q., Chen, W., & Tian, F. (2024) · Food Reviews International · doi:10.1080/87559129.2024.2383854 · Cited by 8

Alleviating D-Galactose-Induced Aging in Mice by Modulating Gut-Liver Axis Using Lactiplantibacillus plantarum TY-Y10

Shi, S., Li, X., Zhang, F., Jiang, Z., Wang, J., Zhao, L., Chen, J., Shu, X., Fang, B., Liu, P., et al. (2024) · Foods · doi:10.3390/foods13223618 · Cited by 9

Ribose-induced advanced glycation end products reduce the lifespan in Drosophila melanogaster by changing the redox state and down-regulating the Sirtuin genes

Mishra, L., & Mishra, M. (2024) · Biogerontology · doi:10.1007/s10522-024-10172-0 · Cited by 8

Intestinal metabolites predict treatment resistance of patients with depression and anxiety

Matsuzaki, J., Kurokawa, S., Iwamoto, C., Miyaho, K., Takamiya, A., Ishii, C., Hirayama, A., Sanada, K., Fukuda, S., Mimura, M., et al. (2024) · Gut Pathogens · doi:10.1186/s13099-024-00601-3 · Cited by 8

Exploration of green preparation strategy for Lycium barbarum polysaccharide targeting Bacteroides proliferative and immune-enhancing activities and its potential use in geriatric foods

Liang, L., Lin, L., & Zhao, M. (2024) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2024.131316 · Cited by 8

Dys-R Questionnaire: A Novel Screening Tool for Dysbiosis Linked to Impaired Gut Microbiota Richness

Balmant, B. D., Fonseca, D. C., Rocha, I. M., Callado, L., Torrinhas, R. S. M. D. M., & Waitzberg, D. L. (2023) · Nutrients · doi:10.3390/nu15194261 · Cited by 7

Gut Microbiota and Metabolic Dysregulation in Elderly Diabetic Patients: Is There a Gender-Specific Effect

Piłot, M., Dzięgielewska-Gęsiak, S., Walkiewicz, K. W., Bednarczyk, M., Waniczek, D., & Muc‐Wierzgoń, M. (2025) · Journal of Clinical Medicine · doi:10.3390/jcm14093103 · Cited by 7

The association between a dietary index for the gut microbiota and frailty in older adults: emphasising the mediating role of inflammatory indicators

Yin, H., Qiu, Y., Gan, C., Zhou, Y., Chen, T., & Liang, M. (2025) · Frontiers in Nutrition · doi:10.3389/fnut.2025.1562278 · Cited by 7

Aging: a possible road toward gut microbiota pathoadaptation

Melo-Miranda, R., Pinto, A., Barreto, H. C., Jesus, C. S. H., Gordo, I., Duarte, I. F., & Sousa, A. (2025) · Gut Microbes · doi:10.1080/19490976.2025.2542375 · Cited by 7

Deciphering the anti-aging potential of probiotics: A narrative review on gerobiotics

Hussain, A., Mojgani, N., Koser, N., Siddiqui, M. F., & Ali, S. A. (2025) · The Microbe · doi:10.1016/j.microb.2025.100607 · Cited by 7

Polypharmacy, anticholinergic burden and oral microbiome among U.S. middle-aged and older adults: a representative national survey

Wei, K., Yang, Y., Chen, C., Yang, Y., Hu, K. R., & Chen, Q. (2025) · Journal of Oral Microbiology · doi:10.1080/20002297.2025.2580559 · Cited by 7

Ganoderma lucidum polysaccharides target the gut-brain axis: Unveiling a novel mechanism for ameliorating aging-induced cognitive impairment and oxidative stress

Chen, Y., Zeng, X., Gong, X., Chen, Y., Zhang, X., & Luo, S. (2025) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2025.149519 · Cited by 7

Managing Gut Dysbiosis: Clinical Evidence and Perspectives on Saccharomyces boulardii CNCM I-745 for Diarrhoeal Conditions in Adults and Children

Nardone, G., Cicero, A. F. G., Gallelli, L., & Canani, R. B. (2026) · Microorganisms · doi:10.3390/microorganisms14010150 · Cited by 7

A short-lived fish with long-lasting effects: hallmarks of aging in Nothobranchius furzeri

Savel, O., Lehmann, J., Poyraz, Y. K., & Page, M. M. (2026) · Frontiers in Aging · doi:10.3389/fragi.2025.1741819 · Cited by 7

A Multi‐Organ Atlas Links Gut Microbial Metabolites to Systemic Redox Changes in Aging Mice

Sajid, S., Huang, J., Kong, S., Lai, C., Tan, Z., Shao, Y., & Guo, L. (2026) · Aging Cell · doi:10.1111/acel.70433 · Cited by 7

The skin of the naked mole-rat and its resilience against aging and cancer

Wlaschek, M., Singh, K., Maity, P., & Scharffetter‐­Kochanek, K. (2023) · Mechanisms of Ageing and Development · doi:10.1016/j.mad.2023.111887 · Cited by 7

Association of enterolactone with blood pressure and hypertension risk in NHANES

Weiner, C. M., Khan, S. E., Leong, C., Ranadive, S. M., Campbell, S. C., Howard, J. T., & Heffernan, K. S. (2024) · PLoS ONE · doi:10.1371/journal.pone.0302254 · Cited by 7

Cutting-Edge iPSC-Based Approaches in Studying Host—Microbe Interactions in Neuropsychiatric Disorders

Mihailovich, M., Bajić, S. S., Dinić, M., Đokić, J., Živković, M., Radojević, D., & Golić, N. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms251810156 · Cited by 7

Influence of Early Life Factors on the Breast Milk and Fecal Microbiota of Mother–Newborn Dyads

Cervantes-Monroy, E., Zarzoza-Mendoza, I. C., Canizales‐Quinteros, S., Morán‐Ramos, S., Villa-Morales, J., López-Contreras, B. E., Carmona-Sierra, F. V., & Rodríguez‐Cruz, M. (2024) · Microorganisms · doi:10.3390/microorganisms12112142 · Cited by 7

Identification of disease-specific gut microbial markers in vitiligo

Dou, Y., Niu, Y., Shen, H., Wang, L., Lv, Y., Liu, S., Xie, X., Feng, A., & Liu, X. (2025) · Frontiers in Microbiology · doi:10.3389/fmicb.2025.1499035 · Cited by 7

Synbiotic combination of fructooligosaccharides and probiotics ameliorates the metabolic dysfunction-associated steatotic liver disease

Lee, S. Y., Lee, S.-B., Kwon, G.-H., Song, S. H., Park, J. H., Kim, M. J., Eom, J. A., Lee, K. J., Yoon, S. J., Park, H., et al. (2025) · The Journal of Microbiology · doi:10.71150/jm.2411002 · Cited by 7

Gerobiotics: Exploring the Potential and Limitations of Repurposing Probiotics in Addressing Aging Hallmarks and Chronic Diseases

Mahamud, A. G. M. S. U., Tanvir, I. A., Kabir, M. E., Samonty, I., Chowdhury, M. A. H., & Rahman, M. A. (2025) · Probiotics and Antimicrobial Proteins · doi:10.1007/s12602-025-10501-w · Cited by 7

Mapping the canine gut microbiome: insights from the Dog Aging Project

Bamberger, T., Muller, E., Algavi, Y. M., Greenier, A., Adjangba, C., Slikas, B., Brassington, L., Mariner, B. L., McCoy, B. M., Harrison, B. R., et al. (2026) · Nature Communications · doi:10.1038/s41467-026-73193-y · Cited by 7

Effects of physical distancing by COVID-19 pandemic on diet quality, neurological and immunological markers, and fecal microbiota of Brazilian older women

Longo, P. L., de Aquino, R. D. C., Ortiz, S. R. M., de Oliveira, R. S., Gavioli, A., do Amaral, J. B., Monteiro, F. R., Franco, R. R. D. A., Mereu, G. R., Bachi, A. L. L., et al. (2022) · Frontiers in Nutrition · doi:10.3389/fnut.2022.972100 · Cited by 7

A qualitative study of older adults’ and healthcare professionals’ perspectives on the potential of functional food products to support healthy ageing

O’Mahony, L., O’Shea, E., O’Connor, E. M., Tierney, A. C., Harkin, M., Harrington, J. M., Kennelly, S., Arendt, E. K., O’Toole, P. W., & Timmons, S. (2023) · Journal of Functional Foods · doi:10.1016/j.jff.2023.105689 · Cited by 7

Changes of faecal bacterial communities and microbial fibrolytic activity in horses aged from 6 to 30 years old

Baraille, M., Buttet, M., Grimm, P., Milojevic, V., Julliand, S., & Julliand, V. (2024) · PLoS ONE · doi:10.1371/journal.pone.0303029 · Cited by 7

Stimulation of microbial butyrate synthesis through prebiotics

Simonelli, N., Abraham, A. G., & Medrano, M. (2024) · Food Bioscience · doi:10.1016/j.fbio.2024.105329 · Cited by 7

Microbiome and Hemato-immune Aging

Johansson, A., Ho, N. P. Y., & Takizawa, H. (2024) · Experimental Hematology · doi:10.1016/j.exphem.2024.104685 · Cited by 7

Metagenomic analyses of gut microbiome composition and function with age in a wild bird; little change, except increased transposase gene abundance

Lee, C. Z., Worsley, S. F., Davies, C. S., Sılan, E., Burke, T. A., Komdeur, J., Hildebrand, F., Dugdale, H. L., & Richardson, D. S. (2025) · ISME Communications · doi:10.1093/ismeco/ycaf008 · Cited by 7

The gut microbiome associated with LGI1 ‐antibody encephalitis

Gilbert, E. H., Binks, S. N. M., Damato, V., Uy, C. E., Colmenero, P., Kelly, M., Khalil, M. I., O’Brien, M., Claesson, M. J., Cryan, J. F., et al. (2025) · Epilepsia · doi:10.1111/epi.18556 · Cited by 6

Subcutaneous white adipose tissue–derived extracellular vesicles maintain intestinal homeostasis via IgA biosynthesis in aging mice

Long, K., Liu, P., Wang, Y., Sulaiman, J. E., Hoque, M., Li, G. H., Zhao, D. D., Lee, P.-K., Siu, G. G., Lee, A. W.-T., et al. (2025) · Journal of Clinical Investigation · doi:10.1172/jci188947 · Cited by 6

The association between phenotypic age acceleration and the risk of all-cause and cancer mortality among cancer survivors: NHANES 1999–2018

Luo, L., Fu, J., Wang, X., & Sui, X. (2025) · Scientific Reports · doi:10.1038/s41598-025-30747-2 · Cited by 7

Gut Microbiota, Probiotics, and Aging: Molecular Mechanisms and Implications for Healthy Aging

Kim, J.-Y. (2026) · Journal of Microbiology and Biotechnology · doi:10.4014/jmb.2511.11046 · Cited by 6

Age-driven dysbiosis: gut microbiota in the pathogenesis and treatment of aging disorders

Kopalli, S. R., Wankhede, N. L., Rahangdale, S. R., Sammeta, S. S., Aglawe, M. M., Koppula, S., Taksande, B. G., Upaganlawar, A., Umekar, M. J., & Kale, M. B. (2026) · Biogerontology · doi:10.1007/s10522-026-10389-1 · Cited by 6

The gut as a central hub for multi-organ crosstalk in aging

Zhang, X., Li, R., Gao, Y., Zhang, W., Ni, T., & Liu, Y. (2026) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-026-06129-w · Cited by 7

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

Mehl, A., & Blacher, E. (2026) · FEBS Letters · doi:10.1002/1873-3468.70324 · Cited by 6

Microbiota and immune-related adverse events in cancer immunotherapy

Schneider, S. M., Fan, C., Wang, Y., Jenq, R. R., & Watowich, S. S. (2026) · Nature reviews. Cancer · doi:10.1038/s41568-026-00921-3 · Cited by 6

Vascular Aging

Wang, R., Chan, S. Y., & Finkel, T. (2026) · Circulation · doi:10.1161/circulationaha.125.075567 · Cited by 6

Lactiplantibacillus plantarum CCFM8610 mitigates oxidative stress-related intestinal aging through its metabolite indole-3-lactic acid

Fang, J., Dai, Y., Chen, J., Zhang, H., Li, H., & Chen, W. (2025) · Food Bioscience · doi:10.1016/j.fbio.2024.105822 · Cited by 6

Comparison of In Vitro Biotransformation of Olive Polyphenols Between Healthy Young and Elderly

Lauwers, S., Weyns, A.-S., Breynaert, A., Rillaer, T. V., Huynegem, V. V., Fransén, E., Bittremieux, W., Lebeer, S., Tuenter, E., & Hermans, N. (2025) · Metabolites · doi:10.3390/metabo15010026 · Cited by 6

The role of the gut microbiome in Alzheimer's disease

Łysiak, K., & Łysiak, A. (2024) · Prospects in Pharmaceutical Sciences · doi:10.56782/pps.273 · Cited by 6

Unlocking the therapeutic potential of gut microbiota for preventing and treating aging-related neurological disorders

Garg, G., Trisal, A., & Singh, A. K. (2025) · Neuroscience · doi:10.1016/j.neuroscience.2025.03.020 · Cited by 6

Age related gut microbiota regulates energy-related metabolism to influence natural aging phenotypes in the heart

Wu, S., Qiao, L., Liu, H., Li, Y., Wang, R., Yin, Y., Li, E., Wang, L., Guan, X., Yin, L., et al. (2025) · Experimental Gerontology · doi:10.1016/j.exger.2025.112734 · Cited by 6

Gut Microbiota and Ageing: Mechanisms, Age-Related Diseases, and Therapeutic Perspectives

Ferreira, J. M. A., Тукаєв, С., & Giannouli, V. (2026) · Healthcare · doi:10.3390/healthcare14142117 · Cited by 4

Ageing, microbes and health

O’Toole, P. W. (2024) · Microbial Biotechnology · doi:10.1111/1751-7915.14477 · Cited by 14

The human gut microbiome and aging

Bradley, E. S., & Haran, J. P. (2024) · Gut Microbes · doi:10.1080/19490976.2024.2359677 · Cited by 197

Gut microbiome and healthy ageing: a systematic review of literature

Almatrafi, R., Alqurainy, N., Hakami, M., Ajina, R., Alrabiah, S., Arafah, A. M., Alotibi, R. S., & Aldriwesh, M. G. (2026) · Microbiology · doi:10.1099/mic.0.001779

Gut microbiome in healthy aging versus those associated with frailty

Lim, M. Y., & Nam, Y. (2023) · Gut Microbes · doi:10.1080/19490976.2023.2278225 · Cited by 72