The gut microbiome as a modulator of healthy ageing

The Hallmarks of Aging

López-Otín, C., Blasco, M. A., Partridge, L., Serrano, M., & Kroemer, G. (2013) · Cell · doi:10.1016/j.cell.2013.05.039 · Cited by 14,982

The Microbiota-Gut-Brain Axis

Cryan, J. F., O'Riordan, K. J., Cowan, C. S. M., Sandhu, K. V., Bastiaanssen, T. F. S., Boehme, M., Codagnone, M. G., Cussotto, S., Fulling, C., Golubeva, A. V., et al. (2019) · Physiological Reviews · doi:10.1152/physrev.00018.2018 · Cited by 5,286

Faecalibacterium prausnitzii is an anti-inflammatory commensal bacterium identified by gut microbiota analysis of Crohn disease patients

Sokol, H., Pigneur, B., Watterlot, L., Lakhdari, O., Bermúdez-Humarán, L. G., Gratadoux, J.-J., Blugeon, S., Bridonneau, C., Furet, J.-P., Corthier, G., et al. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0804812105 · Cited by 4,413

Evolution of mammals and their gut microbes

Ley, R. E., Hamady, M., Lozupone, C., Turnbaugh, P. J., Ramey, R. R., Bircher, J. S., Schlegel, M. L., Tucker, T. A., Schrenzel, M. D., Knight, R., et al. (2008) · Science · doi:10.1126/science.1155725 · Cited by 3,747

The Human Intestinal Microbiome in Health and Disease

Lynch, S. V., & Pedersen, O. (2016) · New England Journal of Medicine · doi:10.1056/nejmra1600266 · Cited by 3,637

Gut microbiota composition correlates with diet and health in the elderly

Claesson, M. J., Jeffery, I. B., Conde, S., Power, S. E., O’Connor, E. M., Cusack, S., Harris, H. M. B., Coakley, M., Lakshminarayanan, B., O’Sullivan, O., et al. (2012) · Nature · doi:10.1038/nature11319 · Cited by 3,314

Supplementation with Akkermansia muciniphila in overweight and obese human volunteers: A proof-of-concept exploratory study

Depommier, C., Everard, A., Druart, C., Plovier, H., Van Hul, M., Vieira-Silva, S., Falony, G., Raes, J., Maiter, D., Delzenne, N. M., et al. (2019) · Nature Medicine · doi:10.1038/s41591-019-0495-2 · Cited by 2,357

The role of the gut microbiota in nutrition and health

Flint, H. J., Scott, K. P., Louis, P., & Duncan, S. H. (2012) · Nature Reviews Gastroenterology & Hepatology · doi:10.1038/nrgastro.2012.156 · Cited by 2,283

Human gut microbes impact host serum metabolome and insulin sensitivity

Pedersen, H. K., Gudmundsdottir, V., Nielsen, H. B., Hyotylainen, T., Nielsen, T., Jensen, B. A. H., Forslund, K., Hildebrand, F., Prifti, E., Falony, G., et al. (2016) · Nature · doi:10.1038/nature18646 · Cited by 2,116

Effects of a Balanced Diet and Probiotics on Blood Biomarkers and Gut Microbiota in the Elderly: A Community-Based Intervention Study

Park, J., Lee, Y., Lee, D., Hong, J., Park, S., Lee, B. W., Park, S. M., & Lee, H. (2025) · Nutrients · doi:10.3390/nu17111933 · Cited by 6

Nicotine Reprograms Aging‐Related Metabolism and Protects Against Motor Decline in Mice

Jia, S., Jing, X., Wang, R., Su, M., Wang, P., Feng, Y., Ren, X., Tu, L., Wei, P., Lu, Z. Z., et al. (2025) · Advanced Science · doi:10.1002/advs.202415311 · Cited by 6

Microbial diversity in drug-naïve Parkinson’s disease patients

Papić, E., Rački, V., Hero, M., Zimani, A. N., Sajko, M. Č., Rožmarić, G., Čizmarević, N. S., Ostojić, S., Kapović, M., Hauser, G., et al. (2025) · PLoS ONE · doi:10.1371/journal.pone.0328761 · Cited by 6

Chemical modulation of gut bacterial metabolism induces colanic acid and extends the lifespan of nematode and mammalian hosts

Hu, G., Savini, M., Cooke, M. B., Wei, X. L., Deng, D., Gao, S. M., Xia, R. A., Guan, Y., Wen, A. X., Yu, X., et al. (2025) · PLoS Biology · doi:10.1371/journal.pbio.3002749 · Cited by 6

Association of Gut Microbiota With Objective Sleep Measures in Women With and Without Human Immunodeficiency Virus Infection: The IDOze Study

Zhang, Y., Lin, C. L., Weber, K. M., Xing, J., Peters, B. A., Sollecito, C. C., Grassi, E., Wiek, F., Xue, X., Seaberg, E. C., et al. (2023) · The Journal of Infectious Diseases · doi:10.1093/infdis/jiad371 · Cited by 6

Does a pickle a day keep Alzheimer's away? Fermented food in Alzheimer's disease: A review

Tyliszczak, M., Wiatrak, B., Danielewski, M., Szeląg, A., Kucharska, A. Z., & Sozański, T. (2023) · Experimental Gerontology · doi:10.1016/j.exger.2023.112332 · Cited by 6

Signatures of disease outcome severity in the intestinal fungal and bacterial microbiome of COVID-19 patients

Rizzello, F., Viciani, E., Gionchetti, P., Filippone, E., Imbesi, V., Melotti, L., Dussias, N. K., Salice, M., Santacroce, B., Padella, A., et al. (2024) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2024.1352202 · Cited by 6

Lactobacillus paracasei subsp. paracasei 2004 improves health and lifespan in Caenorhabditis elegans

Kishimoto, S., Nono, M., Makizaki, Y., Tanaka, Y., Ohno, H., Nishida, E., & Uno, M. (2024) · Scientific Reports · doi:10.1038/s41598-024-60580-y · Cited by 6

The influence of aging and the microbiome in multiple sclerosis and other neurologic diseases

Fettig, N. M., Pu, A., Osborne, L. C., & Gommerman, J. L. (2024) · Immunological Reviews · doi:10.1111/imr.13361 · Cited by 7

Possible Role of Tauroursodeoxycholic Acid (TUDCA) and Antibiotic Administration in Modulating Human Gut Microbiota in Home Enteral Nutrition Therapy for the Elderly: A Case Report

Francini, E., Orlandoni, P., Sparvoli, D., Peladic, N. J., Cardelli, M., Recchioni, R., Silvi, S., Stocchi, V., Zeppa, S. D., Procopio, A. D., et al. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25137115 · Cited by 6

Aging Modulates the Effect of Dietary Glycemic Index on Gut Microbiota Composition in Mice

Zhu, Y., Yeo, E. N., Smith, K., Greenberg, A. S., & Rowan, S. (2024) · Journal of Nutrition · doi:10.1016/j.tjnut.2024.07.014 · Cited by 6

Impact of gut microbiota on cardiac aging

Yin, Z., Fu, L., Wang, Y., & Tai, S. (2024) · Archives of Gerontology and Geriatrics · doi:10.1016/j.archger.2024.105639 · Cited by 6

Bioactive fraction of Musa balbisiana seed mitigates D-galactose-induced brain aging via SIRT1/PGC-1α/FoxO3a activation and intestinal barrier dysfunction by modulating gut microbiota and core metabolites

Gurumayum, N., Devi, M. B., Khound, P., Bhattacharya, A., Sarma, H., Khan, M. R., & Devi, R. (2024) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2024.11.016 · Cited by 6

Methods to extract and study the biological effects of murine gut microbiota using Caenorhabditis elegans as a screening host

la Rosa, C. M. A.-D., Miard, S., Taubert, S., & Picard, F. (2023) · PLoS ONE · doi:10.1371/journal.pone.0281887 · Cited by 6

Model organism life extending therapeutics modulate diverse nodes in the drug-gene-microbe tripartite human longevity interactome

Salekeen, R., Lustgarten, M. S., Khan, U., & Islam, K. M. D. (2023) · Journal of Biomolecular Structure and Dynamics · doi:10.1080/07391102.2023.2192823 · Cited by 6

Unlocking the potential for microbiome‐based therapeutics to address the sustainable development goal of good health and wellbeing

Gulliver, E. L., Simone, S. K. D., Chonwerawong, M., & Forster, S. C. (2024) · Microbial Biotechnology · doi:10.1111/1751-7915.70041 · Cited by 5

Combination of Inulin and Resistant Dextrin Has Superior Prebiotic Effects and Reduces Gas Production During In Vitro Fermentation of Fecal Samples from Older People

Yoshida, K., Kokubo, E., Morita, S., Sonoki, H., & Miyaji, K. (2024) · Nutrients · doi:10.3390/nu16244262 · Cited by 5

Healthy Aging and the Gut Microbiome in People With and Without HIV

Peters, B. A., Xue, X., Hanna, D. B., Wang, Y., Wang, Z., Sharma, A., Floris-Moore, M., Konkle‐Parker, D. J., Alcaide, M. L., Sheth, A. N., et al. (2025) · The Journal of Infectious Diseases · doi:10.1093/infdis/jiae644 · Cited by 5

TAS2R5 and TAS2R38 are bitter taste receptors whose colonic expressions could play important roles in age-associated processes

Jalševac, F., Segú, H., Balaguer, F., Ocaña, T., Moreira, R., Abad‐Jordà, L., Gracia‐Sancho, J., Fernández‐Iglesias, A., Andrés‐Lacueva, C., Martínez‐Huélamo, M., et al. (2025) · The Journal of Nutritional Biochemistry · doi:10.1016/j.jnutbio.2025.109872 · Cited by 5

Associations of microbiome pathophysiology with social activity and behavior are mediated by epigenetic modulations: Avenues for designing innovative therapeutic strategies

Nohesara, S., Abdolmaleky, H. M., Dickerson, F., Pinto‐Tomás, A. A., Jeste, D. V., & Thiagalingam, S. (2025) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2025.106208 · Cited by 5

Grape Seed Proanthocyanidins: A Potential Microbiome‐Targeted Intervention for Healthy Aging in Rats

Sierra‐Cruz, M., Vilalta, A., Miguéns‐Gómez, A., Park, H., Rodríguez‐Gallego, E., Blay, M., Ardèvol, A., Pinent, M., Behmoaras, J. V., Beltrán‐Debón, R., et al. (2025) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.70150 · Cited by 5

Vital Role of Visceral Adipose Tissue in Maintaining Cognitive Functions

Shirafuji, R., Amagase, Y., Goto, A., & Takei, Y. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms26146597 · Cited by 5

Systems and Molecular Biology of Longevity and Preventive Medicine: Brain-Energy–Microbiome–Exposome Synergies in Blue Zones and the Cilento Case

Aliberti, S. M., Capunzo, M., & Funk, R. H. W. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms26167887 · Cited by 5

Sea cucumber polypeptide ameliorates aging properties via the brain-gut axis in naturally aging mice

Feng, C., Shou, Y., Wu, S., Mo, H., Mao, X., Huang, H., Lu, Q., Li, X., Lu, L., Su, Z., et al. (2025) · Chinese Medicine · doi:10.1186/s13020-025-01201-2 · Cited by 5

The Gut–brain–immune Triad in Neurodegeneration: An Integrated Perspective

Chakrabarti, S. K., & Chattopadhyay, D. (2025) · Journal of Translational Gastroenterology · doi:10.14218/jtg.2025.00027 · Cited by 5

Impact of aging on gut-lung-adipose tissue interactions and lipid metabolism during influenza infection in mice

Bogard, G., Makki, K., Rodrigues, P. B., Tan, J., Molendi‐Coste, O., Barthelemy, J., Descat, A., Bouilloux, F., Lecœur, C., Grangette, C., et al. (2025) · Scientific Reports · doi:10.1038/s41598-025-21363-1 · Cited by 5

Towards global healthy longevity: report from the 1st World Longevity Summit in Kyotango, Japan

Kitani, T., Matoba, S., Naito, Y., Horvath, S., Yoshimori, T., Chan, F. K. L., 松田, 智., Bandini, S., Nakagami, H., Morishita, R., et al. (2025) · npj Aging · doi:10.1038/s41514-025-00279-0 · Cited by 5

Bacterial exopolysaccharides mediate activation of flavin-containing monooxygenase 2 to extend lifespan in Caenorhabditis elegans

Jakovljević, S., Radojević, D., Bajić, S. S., Brdarić, E., Mitrović, H., Đokić, J., Baumann, L. C., Trifunović, A., Golić, N., & Dinić, M. (2025) · Cell Communication and Signaling · doi:10.1186/s12964-025-02567-4 · Cited by 5

Boron Bioavailability Revisited: From Plasma-Accessible Species to Microbiota-Accessible Complexes—Implications for Nutritional Essentiality

Biţă, A., Scorei, I. R., Soriano-Ursua, M. A., Pisoschi, C. G., Biță, C. E., Dincă, L., Ștefănescu, S., Racu, M.-V., Pînzaru, I., Florescu, C., et al. (2025) · Biomolecules · doi:10.3390/biom15121711 · Cited by 5

Synergistic Effects of Plant Polysaccharides and Probiotics: A Novel Dietary Approach for Parkinson’s Disease Intervention

Jin, Y. H., Wang, L., Lin, R., He, J., Liu, D., Liu, Y., & Deng, Y. (2026) · Pharmaceuticals · doi:10.3390/ph19010157 · Cited by 5

Mechanistic Links Between the Gut Microbiome and Longevity Therapeutics

Garzon-Escamilla, N., Medina-Cardena, M., Roy, P., Trent, J., Jamous, J., Somesan, Y., & Denslow, S. (2026) · Biomedicines · doi:10.3390/biomedicines14020316 · Cited by 5

Effect of bedrest on the human gut and oral microbiome: implications for frailty

Alvaro-Fuss, M., DeClercq, V., Blodgett, J. M., Theou, O., Langille, M. G. I., & Beiko, R. G. (2026) · Experimental Gerontology · doi:10.1016/j.exger.2026.113079 · Cited by 5

Processed Diets and Food Additives Shape the Gut Microbiota and Chronic Disease Risk Across the Life Course—A Three-Layer Ecosystem Disruption Model (TLED) Model

Profir, M., Pavelescu, L. A., Mogoș, G. F. R., Stancu, A. C., Creţoiu, S. M., & Marinescu, I. P. (2026) · Life · doi:10.3390/life16030505 · Cited by 5

Gut microbiota orchestrates bone homeostasis: a multi-pathway network from intestine to skeleton

Gong, Y., Ma, X., Wang, L., Zhang, P., Liu, T., Li, Y. D., & Dong, W. (2026) · Frontiers in Endocrinology · doi:10.3389/fendo.2026.1767726 · Cited by 5

Probiotics: From natural to artificial

Liu, L.-H., Zhang, X., Huang, Y., Chen, R., Huang, J., Wang, S., Li, W., & Jiang, A. (2026) · Biotechnology Advances · doi:10.1016/j.biotechadv.2026.108916 · Cited by 5

The microbiome-gerogene axis: a new frontier in precision geromedicine

Bautista, J., & López‐Cortés, A. (2026) · Frontiers in Aging · doi:10.3389/fragi.2026.1794192 · Cited by 5

Gut microbial age modulates cardiovascular disease risk in metabolically unhealthy older people

(2024) · Nature Medicine · doi:10.1038/s41591-024-03058-8 · Cited by 5

Gut microbiome and orthopaedic health: Bridging the divide between digestion and bone integrity

Jeyaraman, N., Jeyaraman, M., Dhanpal, P., Ramasubramanian, S., Ragavanandam, L., Muthu, S., Santos, G. S., da Fonseca, L. F., & Lana, J. F. (2024) · World Journal of Orthopedics · doi:10.5312/wjo.v15.i12.1135 · Cited by 5

Synthetic β- d -Glucuronides: Substrates for Exploring Glucuronide Degradation by Human Gut Bacteria

Gorecka, A., Schacht, H., Fraser, M. K., Teriosina, A., London, J. A., Barsukov, I., Powell, A. K., Cartmell, A., Stachulski, A. V., & Yates, E. A. (2024) · ACS Omega · doi:10.1021/acsomega.4c09036 · Cited by 5

Exploring the Pharmacokinetics and Gut Microbiota Modulation of Hesperidin and Nobiletin from Mandarin Orange Peel in Experimental Dogs: A Pilot Study

Nakahigashi, J., Kurikami, M., Iwai, S., Iwamoto, S., Kobayashi, S., & Kobayashi, E. (2024) · Metabolites · doi:10.3390/metabo15010003 · Cited by 5

Investigation of Pancreatic-beta Cells Role in the Biological Process of Ageing

Chaudhary, R., Khanna, J., Rohilla, M., Gupta, S., & Bansal, S. (2023) · Endocrine Metabolic & Immune Disorders - Drug Targets · doi:10.2174/1871530323666230822095932 · Cited by 5

Gut Microbiota and (Neuro)Inflammation: Involvement of Endotoxin in the Pathogenesis of Endogenous Psychoses

Zozulya, S. A., Yakovlev, M. Y., & Klyushnik, T. P. (2023) · Psikhiatriya · doi:10.30629/2618-6667-2023-21-5-86-96 · Cited by 5

Gut Microbes: The Gut Brain Connection

Lynch, C. M. K., O’Riordan, K. J., Clarke, G. A., & Cryan, J. F. (2023) · Springer eBooks · doi:10.1007/978-3-031-46712-7_4 · Cited by 5

Scoring Microbiota Function: A Proposal to Use Features of Evolutionary, Symbiotic Innovation to Recognize a “Healthy” Human Gut Microbiota

Tannock, G. W. (2024) · Gut Microbes Reports · doi:10.1080/29933935.2024.2376543 · Cited by 5

An Optimal Dietary Pattern for Healthy Longevity: Scoping Differencing Review between the Mediterranean and the Japanese Diet

Vitale, E. (2023) · Endocrine Metabolic & Immune Disorders - Drug Targets · doi:10.2174/0118715303256362230926053558 · Cited by 5

Randomised, Placebo-Controlled Investigation of the Impact of Probiotic Consumption on Gut Microbiota Diversity and the Faecal Metabolome in Seniors

van Zanten, G. C., Madsen, A. L., Yde, C. C., Krych, Ł., Yeung, N., Saarinen, M., Kot, W., Jensen, H. M., Rasmussen, M. A., Ouwehand, A. C., et al. (2024) · Microorganisms · doi:10.3390/microorganisms12040796 · Cited by 6

Investigating the bidirectional interactions between senotherapeutic agents and human gut microbiota

Sangfuang, N., Xie, Y., McCoubrey, L. E., Taub, M., Favaron, A., Mai, Y., Gaisford, S., & Basit, A. W. (2025) · European Journal of Pharmaceutical Sciences · doi:10.1016/j.ejps.2025.107098 · Cited by 5

Lactiplantibacillus plantarum 1008 Promotes Reproductive Function and Cognitive Activity in Aged Male Mice with High-Fat-Diet-Induced Obesity by Altering Metabolic Parameters and Alleviating Testicular Oxidative Damage, Inflammation and Apoptosis

Liu, C.-Y., Tsai, T.-Y., Liu, T.-H., Chang, T.-C., Chen, Y.-W., & Tsao, C. (2024) · Antioxidants · doi:10.3390/antiox13121498 · Cited by 4

The role of secondary genomes in neurodevelopment and co-evolutionary dynamics

Singh, S., Saini, V., & Jha, H. C. (2025) · International review of neurobiology · doi:10.1016/bs.irn.2025.03.008 · Cited by 4

The mechanism of disease progression by aging and age-related gut dysbiosis in multiple sclerosis

Yadav, S. K., Chen, C., Dhib-Jalbut, S. S., & Ito, K. (2025) · Neurobiology of Disease · doi:10.1016/j.nbd.2025.106956 · Cited by 4

Exploring Individual Factors Affecting Endothelial Function Response Variability in Aging: Implications for Precision Nutrition

Woolf, E. K., & Redman, L. M. (2025) · Nutrients · doi:10.3390/nu17142285 · Cited by 4

Blood-borne immune cells carry low biomass DNA remnants of microbes in patients with colorectal cancer or inflammatory bowel disease

Morsy, Y., Walberg, Ã., Wawrzyniak, P., Hubeli, B., Truscello, L., Mamie, C., Niechcial, A., Gueguen, E., Manzini, R., Gottier, C., et al. (2025) · Gut Microbes · doi:10.1080/19490976.2025.2530157 · Cited by 4

Sex‐Specific Aging Patterns of Gut Microbiota in Urban Chinese Adults: Guild‐Based Analysis and Implications for Healthy Aging

Fu, J., Xu, W., Yu, D., Jiang, Y., Wang, L., Cai, H., Xia, Q., Shu, X., & Zheng, W. (2025) · Aging Cell · doi:10.1111/acel.70192 · Cited by 4

Microbiome drives age-dependent shifts in brain transcriptomic programs at the single-cell level in Drosophila

Zhao, D., Shiga, R. T., Song, Z., Shu, R., Loo, L., & Wong, A. C.-N. (2025) · npj Biofilms and Microbiomes · doi:10.1038/s41522-025-00781-z · Cited by 4

The Brain-Gut-Microbiome Axis Across the Life Continuum and the Role of Microbes in Maintaining the Balance of Health

Halverson, T., & Alagiakrishnan, K. (2025) · Journal of Integrative Neuroscience · doi:10.31083/jin36616 · Cited by 4

Microbial modulators of the mind: probiotic interventions in hippocampal neurogenesis and cognitive flexibility

Zhao, J., Liu, H., & Badehnoosh, B. (2025) · Antonie van Leeuwenhoek · doi:10.1007/s10482-025-02162-0 · Cited by 4

Potential dietary geroprotectors and their impact on key mechanisms of aging

Moskalev, A., & Veselova, O. M. (2025) · Biogerontology · doi:10.1007/s10522-025-10355-3 · Cited by 4

Microbe–Diet Interactions and Personalized Nutrition

Kujawska, M., & Hall, L. J. (2025) · Annual Review of Food Science and Technology · doi:10.1146/annurev-food-111523-121845 · Cited by 4

Crocetin as a Neuroprotective Agent: Targeting Western Diet-Induced Cognitive Dysfunction Through Antioxidant, Anti-Inflammatory and Gut-Brain Axis Modulation

Babu, K. S., Gupta, V., Dar, A. A., Sheikh, J. A., Kumar, D., Choudhary, N., Tanwar, R., Gupta, S., Rani, P., & Arunprasad, V. K. (2025) · ASN NEURO · doi:10.1080/17590914.2025.2603409 · Cited by 4

Integrative analysis across metagenomic taxonomic classifiers: A case study of the gut microbiome in aging and longevity in the Integrative Longevity Omics Study

Karagiannis, T. T., Chen, Y., Bald, S., Tai, A., Reed, E. R., Milman, S., Andersen, S. L., Perls, T. T., Segrè, D., Sebastiani, P., et al. (2026) · PLoS Computational Biology · doi:10.1371/journal.pcbi.1013883 · Cited by 4

Fermented and non-fermented pickles modulate gut microbiota in older adults with dysphagia: A pilot crossover study

Mayama, T., Nakagawa, K., Ogata, Y., Yoshimi, K., Ishii, M., Moritoyo, R., Yanagida, R., Yamaguchi, K., & Tohara, H. (2026) · Clinical Nutrition ESPEN · doi:10.1016/j.clnesp.2026.102918 · Cited by 4

Multifactorial Mechanisms and Therapeutic Role of the Gut Microbiota in Sarcopenic Obesity: Role of Lifestyle and Gut Microbiota–Derived Metabolites

Tao, Y., Wang, Z., Wang, Q., & Zhong, S. (2025) · Nutrition Reviews · doi:10.1093/nutrit/nuaf274 · Cited by 4

Premature aging in serious mental illness

Diniz, B. S., Fries, G. R., Kuo, C.-L., Xu, M., & Lenze, E. J. (2026) · Neuropsychopharmacology · doi:10.1038/s41386-026-02322-4 · Cited by 4

Dysbiosis and the gut–brain axis impairment in the pathophysiology of Alzheimer’s disease and related dementias: is ‘pathobiome’ an etiological element?

Park, G., Chakrabarty, P., Efron, P. A., & Nagpal, R. (2025) · Essays in Biochemistry · doi:10.1042/ebc20253055 · Cited by 4

Abundance-weighted pathway mapping demonstrates family-level structure of butyrate and propionate production across the human gut microbiome

Christensen, R. D., Wang, Y., Arnoldini, M., & Cremer, J. (2026) · ISME Communications · doi:10.1093/ismeco/ycag075 · Cited by 4

Cancer and aging: complex associations and therapeutic targets

Liang, J., Zang, S., Zhe, W. A. N. G., & Zhang, R. (2026) · Molecular Biomedicine · doi:10.1186/s43556-026-00423-6 · Cited by 4

The impact of ageing on faecal short chain fatty acids levels in apparently healthy adults: A systematic review and meta-analysis

Alqarni, S., Pugh, J. E., Deremiens, V., Lett, A. M., Morrison, D. J., Riddell, N. E., Frost, G. S., & Chambers, E. S. (2026) · Ageing Research Reviews · doi:10.1016/j.arr.2026.103128 · Cited by 4

Microbial keystone taxa and metabolic signatures in centenarians regulate intestinal homeostasis during aging

Lin, W.-C., Zhang, C., Lei, H., Cao, Z., Gao, X., Yu, W., Li, X., Xiang, Q., Zhang, Z.-W., Pang, S., et al. (2026) · iMeta · doi:10.1002/imt2.70134 · Cited by 4

Temporal variations of the gut microbiome in human health

Zeng, S., Almeida, A., Mu, D., & Wang, S. (2026) · The Lancet Microbe · doi:10.1016/j.lanmic.2026.101388 · Cited by 4

Gut microbiota associates with frailty in older women

Geraldi, M. V., Dwibedi, C. K., Jaiswal, R., Gregori, G., Zhou, X., Lv, B., Zheng, Y., Wang, X., Wu, H., Axelsson, K. F., et al. (2026) · Nature Communications · doi:10.1038/s41467-026-75176-5 · Cited by 4

Gut Microbiota and Ageing: Mechanisms, Age-Related Diseases, and Therapeutic Perspectives

Ferreira, J. M. A., Тукаєв, С., & Giannouli, V. (2026) · Healthcare · doi:10.3390/healthcare14142117 · Cited by 4

Gut microbiota in health and disease

Li, Y. N., Xiao, X., Jiang, X., Li, X., WANG, W., & Lin, R. (2026) · Molecular Biomedicine · doi:10.1186/s43556-026-00512-6 · Cited by 6

Gut microbiota: an ideal biomarker and intervention strategy for aging

Xu, X., Xu, T., Wei, J., & Chen, T. (2023) · Microbiome Research Reports · doi:10.20517/mrr.2023.68 · Cited by 4

Age and sex-related variations in murine laryngeal microbiota

An, R., Venkatraman, A., Binns, J., Saric, C., Rey, F. E., & Thibeault, S. L. (2024) · PLoS ONE · doi:10.1371/journal.pone.0300672 · Cited by 4

Does Microbiome Contribute to Longevity? Compositional and Functional Differences in Gut Microbiota in Chinese Long-Living (>90 Years) and Elderly (65–74 Years) Adults

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