The DOI matches its Crossref record; 156 of the 156 references it cites were found in a registry or an index.
Interactions of commensal and pathogenic microorganisms with the intestinal mucosal barrier
Abstract
The intestinal mucosal barrier is composed of epithelial cells that are protected by an overlying host-secreted mucous layer and functions as the first line of defence against pathogenic and non-pathogenic microorganisms. Some microorganisms have evolved strategies to either survive in the mucosal barrier or circumvent it to establish infection. In this Review, we discuss the current state of knowledge of the complex interactions of commensal microorganisms with the intestinal mucosal barrier, and we discuss strategies used by pathogenic microorganisms to establish infection by either exploiting different epithelial cell lineages or disrupting the mucous layer, as well as the role of defects in mucus production in chronic disease.
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“As mucin- and junction-degrading bacteria can cause damage, these enzymes may provide targets for protease inhibitors to treat or prevent intestinal diseases.25,117”
From The emerging roles of bacterial proteases in intestinal diseases (2023) · cites this paper as [117]
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Рецензия на статью: СТРУКТУРНЫЕ ОСОБЕННОСТИ ХИМУСА И ЭНТЕРАЛЬНЫЙ МЕТАБОЛИЗМ КАЛЬЦИЯ У ПЕСЦОВ
журнала, С. Р. М. Н.-И. (2026) · Cifra LLC Journals · doi:10.60797/irj.2026.172.72.5
Содержание кальция во фракциях химуса
Ksenofontov, D. A. (2026) · Cifra LLC Journals · doi:10.60797/irj.2026.172.72.4
Содержание кальция в стенке кишечника
Ksenofontov, D. A. (2026) · Cifra LLC Journals · doi:10.60797/irj.2026.172.72.3
СТРУКТУРНЫЕ ОСОБЕННОСТИ ХИМУСА И ЭНТЕРАЛЬНЫЙ МЕТАБОЛИЗМ КАЛЬЦИЯ У ПЕСЦОВ
Ksenofontov, D. A. (2026) · Cifra LLC Journals · doi:10.60797/irj.2026.172.72
Соотношение фракций в сухом веществе химуса
Ksenofontov, D. A. (2026) · Cifra LLC Journals · doi:10.60797/irj.2026.172.72.1
Metadata
- Authors
- Martens, E. C., Neumann, M., & Desai, M. S.
- Affiliations
- University of Michigan (US)
- Luxembourg Institute of Health (LU)
- University of Southern Denmark (DK)
- Corresponding author
- Martens, Eric C.
- Desai, Mahesh S.
- Venue
- Nature Reviews Microbiology
- Published
- 2018-06-14
- Volume
- 16
- Issue
- 8
- Pages
- 457-470
- ISSN
- 1740-1526 (ISSN-L)
- 1740-1534
- OpenAlex
- W2807724532
- Cited by
- 711
- References
- 156
- Citations by year
- 2026: 62 · 2025: 93 · 2024: 106 · 2023: 104 · 2022: 149 · 2021: 96 · 2020: 54 · 2019: 41 · 2018: 6
- FWCI
- 4.82
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Nature Reviews Microbiology (publishedVersion)
- PubMed (publishedVersion)
- University of Southern Denmark Research Portal (University of Southern Denmark) (submittedVersion)
- Funders
- Kenneth Rainin Foundation
- National Institutes of Health
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Gut microbiota and health
- Life Sciences › Immunology and Microbiology › Microbiology › Escherichia coli research studies
- Health Sciences › Medicine › Gastroenterology › Gastrointestinal motility and disorders
- Keywords
- intestinal barrier, commensal microorganisms, enteric pathogens, mucus layer, intestinal epithelial cells, host defense, chronic intestinal diseases
- MeSH terms
- Bacteria, Humans, Intestinal Mucosa, Symbiosis, Bacterial Physiological Phenomena
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