The DOI matches its Crossref record; 174 of the 174 references it cites were found in a registry or an index.
Diet-microbiota interactions and personalized nutrition
Abstract
Conceptual scientific and medical advances have led to a recent realization that there may be no single, one-size-fits-all diet and that differential human responses to dietary inputs may rather be driven by unique and quantifiable host and microbiome features. Integration of these person-specific host and microbiome readouts into actionable modules may complement traditional food measurement approaches in devising diets that are of benefit to the individual. Although many host-derived factors are hardwired and difficult to modulate, the microbiome may be more readily reshaped by environmental factors such as dietary exposures and is increasingly recognized to potentially impact human physiology by participating in digestion, the absorption of nutrients, shaping of the mucosal immune response and the synthesis or modulation of a plethora of potentially bioactive compounds. Thus, diet-induced microbiota alterations may be harnessed in order to induce changes in host physiology, including disease development and progression. However, major limitations in 'big-data' processing and analysis still limit our interpretive and translational capabilities concerning these person-specific host, microbiome and diet interactions. In this Review, we describe the latest advances in understanding diet-microbiota interactions, the individuality of gut microbiota composition and how this knowledge could be harnessed for personalized nutrition strategies to improve human health.
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“Because of infinite confounders such as medication history, geographical variation in food availability and quality, and host-specific factors, there is large interindividual variation between the responses to dietary interventions for PD, as seen for other chronic conditions [187].”
From The gut–brain axis in early Parkinson’s disease: from prodrome to prevention (2025) · cites this paper as [187]
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“Microbiome-mediated links between diet and health have been prevalently investigated by considering the role of the abiotic components of foods. 35-41”
From Unexplored microbial diversity from 2,500 food metagenomes and links with the human microbiome. (2024) · cites this paper as [35]
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Metadata
- Authors
- Kolodziejczyk, A. A., Zheng, D., & Elinav, E.
- Affiliations
- Weizmann Institute of Science (IL)
- Sun Yat-sen University (CN)
- German Cancer Research Center (DE)
- Corresponding author
- Elinav, Eran
- Venue
- Nature Reviews Microbiology
- Published
- 2019-09-20
- Volume
- 17
- Issue
- 12
- Pages
- 742-753
- ISSN
- 1740-1526 (ISSN-L)
- 1740-1534
- OpenAlex
- W2974721962
- Cited by
- 879
- References
- 174
- Citations by year
- 2026: 89 · 2025: 122 · 2024: 131 · 2023: 125 · 2022: 143 · 2021: 175 · 2020: 88 · 2019: 6
- FWCI
- 9.14
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Nature Reviews Microbiology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Gut microbiota and health
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Nutrition, Genetics, and Disease
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Nutritional Studies and Diet
- Keywords
- diet-microbiome interactions, gut microbiota, personalized nutrition, host-microbiome interactions, host physiology, mucosal immune response, nutrient absorption, disease development, big data analytics
- MeSH terms
- Gastrointestinal Microbiome, Host Microbial Interactions, Diet, Humans, Individuality, Precision Medicine, Microbiota
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
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