Cellular adaptation to hypoxia through hypoxia inducible factors and beyond

Repertoires of Autophagy in the Pathogenesis of Ocular Diseases

Li, Y., Jiang, Q. L., Cao, G.-F., Yao, J., & Yan, B. (2015) · Cellular Physiology and Biochemistry · doi:10.1159/000373980 · Cited by 16,351

A role for mitochondria in nlrp3 inflammasome activation

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Control of inositol 1,4,5-trisphosphate-induced Ca2+ release by cytosolic Ca2+

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Targeting Hypoxia-Inducible Factors for the Treatment of Anemia in Chronic Kidney Disease Patients

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Mitochondria, Oxidants, and Aging

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The unfolded protein response: controlling cell fate decisions under ER stress and beyond

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XBP1 mRNA Is Induced by ATF6 and Spliced by IRE1 in Response to ER Stress to Produce a Highly Active Transcription Factor

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HIF-1-mediated expression of pyruvate dehydrogenase kinase: A metabolic switch required for cellular adaptation to hypoxia

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Mutation of the mouse klotho gene leads to a syndrome resembling ageing

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Role of inflammatory microenvironment: potential implications for improved breast cancer nano-targeted therapy

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The Normobaric Oxygen Paradox—Hyperoxic Hypoxic Paradox: A Novel Expedient Strategy in Hematopoiesis Clinical Issues

Salvagno, M., Coppalini, G., Taccone, F. S., Strapazzon, G., Mrakic‐Sposta, S., Rocco, M., Khalifé, M., & Balestra, C. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms24010082 · Cited by 43

Macrophage Polarization Induced by Bacteria‐Responsive Antibiotic‐Loaded Nanozymes for Multidrug Resistance‐Bacterial Infections Management

Zhu, X., Guo, J., Yang, Y., & Liu, J. (2023) · Small · doi:10.1002/smll.202204928 · Cited by 39

Hypoxia causes pancreatic β‐cell dysfunction and impairs insulin secretion by activating the transcriptional repressor BHLHE40

Tsuyama, T., Sato, Y., Yoshizawa, T., Matsuoka, T., & Yamagata, K. (2023) · EMBO Reports · doi:10.15252/embr.202256227 · Cited by 42

Manganese Oxide-Incorporated Hybrid Lipid Nanoparticles Amplify the Potency of mRNA Vaccine via Oxygen Generation and STING Activation

Gan, J., Lei, J., Li, Y., Lu, M., Yu, X., & Yu, G. (2024) · Journal of the American Chemical Society · doi:10.1021/jacs.4c12166 · Cited by 40

Supramolecular approaches for the treatment of hypoxic regions in tumours

Regeni, I., & Bonnet, S. A. (2025) · Nature Reviews Chemistry · doi:10.1038/s41570-025-00705-7 · Cited by 39

Compartmentalization of adenosine metabolism in cancer cells and its modulation during acute hypoxia

Losenkova, K., Zuccarini, M., Karikoski, M., Laurila, J., Boison, D., Jalkanen, S., & Yegutkin, G. G. (2020) · Journal of Cell Science · doi:10.1242/jcs.241463 · Cited by 41

Targeting MYC at the intersection between cancer metabolism and oncoimmunology

Venkatraman, S., Balasubramanian, B., Thuwajit, C., Meller, J., Tohtong, R., & Chutipongtanate, S. (2024) · Frontiers in Immunology · doi:10.3389/fimmu.2024.1324045 · Cited by 40

Endothelial HIF-2α as a Key Endogenous Mediator Preventing Emphysema

Pasupneti, S., Tian, W., Tu, A. B., Dahms, P. A., Granucci, E. J., Gandjeva, A., Xiang, M., Butcher, E. C., Semenza, G. L., Tuder, R. M., et al. (2020) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.202001-0078oc · Cited by 38

Emerging oncogene ATAD2: Signaling cascades and therapeutic initiatives

Nayak, A., Dutta, M., & Roychowdhury, A. (2021) · Life Sciences · doi:10.1016/j.lfs.2021.119322 · Cited by 38

Two‐Photon Small‐Molecule Fluorogenic Probes for Visualizing Endogenous Nitroreductase Activities from Tumor Tissues of a Cancer Patient

Yu, C., Wang, S., Xu, C., Ding, Y., Zhang, G., Yang, N., Wu, Q., Xiao, Q., Wang, L., Fang, B., et al. (2022) · Advanced Healthcare Materials · doi:10.1002/adhm.202200400 · Cited by 38

Engineered stem cells by emerging biomedical stratagems

Wang, J., Zhang, X., Chen, H., Ren, H., Zhou, M., & Zhao, Y. (2024) · Science Bulletin · doi:10.1016/j.scib.2023.12.006 · Cited by 37

Intermittent hypoxia conditioning as a potential prevention and treatment strategy for ischemic stroke: Current evidence and future directions

Yuan, H., Liu, J., Gu, Y., Ji, X., & Nan, G. (2022) · Frontiers in Neuroscience · doi:10.3389/fnins.2022.1067411 · Cited by 37

Association of NRF2 with HIF-2α-induced cancer stem cell phenotypes in chronic hypoxic condition

Hallis, S. P., Kim, S. K., Lee, J., & Kwak, M. (2023) · Redox Biology · doi:10.1016/j.redox.2023.102632 · Cited by 38

Hypoxia and panvascular diseases: exploring the role of hypoxia-inducible factors in vascular smooth muscle cells under panvascular pathologies

Hu, Y., Zhao, Y., Li, P., Lu, H., Li, H., & Ge, J. (2023) · 中国科学通报：英文版 · doi:10.1016/j.scib.2023.07.032 · Cited by 37

Lipid nanoparticle-mediated hepatocyte delivery of siRNA and silibinin in metabolic dysfunction-associated steatotic liver disease

Lyu, Y., Yang, X., Yang, L., Dai, J., Qin, H., Zhou, Y., Huang, Y., Wang, Y., Wu, D., Shuai, Q., et al. (2024) · Journal of Controlled Release · doi:10.1016/j.jconrel.2024.07.011 · Cited by 37

The immunometabolic topography of cellular organization and bacterial control in tuberculosis granulomas

McCaffrey, E., Delmastro, A. C., Fitzhugh, I., Ranek, J. S., Douglas, S., Peters, J. M., Fullaway, C. C., Bosse, M. M., Liu, C. C., Gillen, C., et al. (2026) · Nature Immunology · doi:10.1038/s41590-026-02431-8 · Cited by 37

Roles of oxygen level and hypoxia-inducible factor signaling pathway in cartilage, bone and osteochondral tissue engineering

Fu, L., Zhang, L., Zhang, X., Chen, L., Cai, Q., & Yang, X. (2021) · Biomedical Materials · doi:10.1088/1748-605x/abdb73 · Cited by 37

Intestinal Inflammation as a Dysbiosis of Energy Procurement: New Insights into an Old Topic

Lee, J. S., Wang, R. X., Alexeev, E. E., & Colgan, S. P. (2021) · Gut Microbes · doi:10.1080/19490976.2021.1880241 · Cited by 37

Hypoxia Drives Dihydropyrimidine Dehydrogenase Expression in Macrophages and Confers Chemoresistance in Colorectal Cancer

Malier, M., Court, M., Gharzeddine, K., Laverierre, M.-H., Marsili, S., Thomas, F., Decaens, T., Roth, G. S., & Millet, A. (2021) · Cancer Research · doi:10.1158/0008-5472.can-21-1572 · Cited by 40

Photomedicine based on heme-derived compounds

Keum, H., Yoo, D., & Jon, S. (2022) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2022.114134 · Cited by 37

HIF signaling: A new propellant in bone regeneration

Bai, H., Wang, Y., Zhao, Y. D., Chen, X., Xiao, Y. M., & Bao, C. (2022) · Biomaterials Advances · doi:10.1016/j.bioadv.2022.212874 · Cited by 37

Hypoxia induces an early primitive streak signature, enhancing spontaneous elongation and lineage representation in gastruloids

López-Anguita, N., Gassaloglu, S. I., Stötzel, M., Typou, M., Virta, I., Hetzel, S., Buschow, R., Koksal, B., Atilla, D., Maitschke-Rajasekharan, R., et al. (2022) · Development · doi:10.1242/dev.200679 · Cited by 40

The Signalling Effects of Photobiomodulation on Osteoblast Proliferation, Maturation and Differentiation: A Review

Crous, A., & Abrahamse, H. (2021) · Stem Cell Reviews and Reports · doi:10.1007/s12015-021-10142-w · Cited by 38

The Role of Hypoxia-Inducible Factor Isoforms in Breast Cancer and Perspectives on Their Inhibition in Therapy

Kozal, K., & Krześlak, A. (2022) · Cancers · doi:10.3390/cancers14184518 · Cited by 37

Resveratrol-induced SIRT1 activation inhibits glycolysis-fueled angiogenesis under rheumatoid arthritis conditions independent of HIF-1α

Jiang, T., Ji, C., Yu, L., Song, M.-K., Li, Y., Liao, Q., Wei, T., Olatunji, O. J., Zuo, J., & Han, J. H. (2023) · Inflammation Research · doi:10.1007/s00011-023-01728-w · Cited by 36

Lactylation: A Novel Post-Translational Modification with Clinical Implications in CNS Diseases

Liu, J., Zhao, F., & Qu, Y. (2024) · Biomolecules · doi:10.3390/biom14091175 · Cited by 37

The SUMO pathway in pancreatic cancer: insights and inhibition

Schneeweis, C., Hassan, Z., Schick, M., Keller, U. B., & Schneider, G. (2020) · British Journal of Cancer · doi:10.1038/s41416-020-01119-6 · Cited by 36

Hypoxia and the integrated stress response promote pulmonary hypertension and preeclampsia: Implications in drug development

Hu, X., & Zhang, L. (2021) · Drug Discovery Today · doi:10.1016/j.drudis.2021.07.011 · Cited by 37

Hypoxia in Cancer and Fibrosis: Part of the Problem and Part of the Solution

Romero, Y., & Aquino‐Gálvez, A. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22158335 · Cited by 39

Redox Dysregulation in the Tumor Microenvironment Contributes to Cancer Metastasis

Liu, W., Wang, B., Zhou, M., Liu, D., Chen, F., Zhao, X., & Lu, Y. (2023) · Antioxidants and Redox Signaling · doi:10.1089/ars.2023.0272 · Cited by 37

Mechanical force induces mitophagy-mediated anaerobic oxidation in periodontal ligament stem cells

Zhang, Z., Cui, S., Fu, Y., Wang, J., Liu, J., & Wei, F. (2023) · Cellular & Molecular Biology Letters · doi:10.1186/s11658-023-00453-w · Cited by 35

Regulatory mechanisms of Sesn2 and its role in multi-organ diseases

Wang, J., Wang, S., Xiao, M., Zhang, J., Wang, J., Guo, Y., Tang, Y., & Gu, J. (2020) · Pharmacological Research · doi:10.1016/j.phrs.2020.105331 · Cited by 36

A Rationale for Hypoxic and Chemical Conditioning in Huntington’s Disease

Burtscher, J., Maglione, V., Pardo, A. D., Millet, G. P., Schwarzer, C., & Zangrandi, L. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22020582 · Cited by 35

Hypoxia-Inducible Factors in Cancer

Kim, L. C., & Simon, M. C. (2022) · Cancer Research · doi:10.1158/0008-5472.can-21-3780 · Cited by 35

Insight into the Effects of High‐Altitude Hypoxic Exposure on Learning and Memory

Zhang, Z.-A., Sun, Y., Yuan, Z., Wang, L., Dong, Q., Zhou, Y., Zheng, G., Aschner, M., Zou, Y., & Luo, W. (2022) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2022/4163188 · Cited by 35

Natural products targeting glycolysis in cancer

Zhao, Y., Chard, L. S., Cheng, Z., Wang, Y., & Si, L. (2022) · Frontiers in Pharmacology · doi:10.3389/fphar.2022.1036502 · Cited by 35

Immune consequences of exercise in hypoxia: A narrative review

Burtscher, J., Pasha, Q., Chanana, N., Millet, G. P., Burtscher, M., & Strasser, B. (2023) · Journal of sport and health science/Journal of Sport and Health Science · doi:10.1016/j.jshs.2023.09.007 · Cited by 34

Nanotechnology‐mediated photodynamic therapy: Focus on overcoming tumor hypoxia

Moloudi, K., Abrahamse, H., & George, B. P. A. (2023) · Wiley Interdisciplinary Reviews Nanomedicine and Nanobiotechnology · doi:10.1002/wnan.1937 · Cited by 34

Exploring Stressors: Impact on Cellular Organelles and Implications for Cellular Functions

Zayani, Z., Matinahmadi, A., Tavakolpournegari, A., & Bidooki, S. H. (2025) · Stresses · doi:10.3390/stresses5020026 · Cited by 35

Hypoxia-inducible long noncoding RNA NPSR1-AS1 promotes the proliferation and glycolysis of hepatocellular carcinoma cells by regulating the MAPK/ERK pathway

He, H., Chen, T., Mo, H., Chen, S., Liu, Q., & Guo, C. (2020) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2020.09.076 · Cited by 34

Rewiring cell signalling pathways in pathogenic mtDNA mutations

Chung, C.-Y., Valdebenito, G. E., Chacko, A. R., & Duchen, M. R. (2021) · Trends in Cell Biology · doi:10.1016/j.tcb.2021.10.005 · Cited by 37

HIF-1α/FOXO1 axis regulated autophagy is protective for β cell survival under hypoxia in human islets

Liang, R., Liu, N., Cao, J., Liu, T., Sun, P., Cai, X., Zhang, L., Liu, Y., Zou, J., Wang, L., et al. (2022) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2022.166356 · Cited by 34

Glucose- and Non-Glucose-Induced Mitochondrial Dysfunction in Diabetic Kidney Disease

Ito, M., Gurumani, M. Z., Merscher, S., & Fornoni, A. (2022) · Biomolecules · doi:10.3390/biom12030351 · Cited by 34

Boosting mitochondrial health to counteract neurodegeneration

Burtscher, J., Romani, M., Bernardo, G., Popa, T., Ziviani, E., Hummel, F. C., Sorrentino, V., & Millet, G. P. (2022) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2022.102289 · Cited by 36

The Role of Imaging Biomarkers to Guide Pharmacological Interventions Targeting Tumor Hypoxia

Gallez, B. (2022) · Frontiers in Pharmacology · doi:10.3389/fphar.2022.853568 · Cited by 35

Outcomes and associated factors of traumatic brain injury among adult patients treated in Amhara regional state comprehensive specialized hospitals

Michael, S. G., Terefe, B., Asfaw, M. G., & Liyew, B. (2023) · BMC Emergency Medicine · doi:10.1186/s12873-023-00859-x · Cited by 35

A comprehensive review on signaling attributes of serine and serine metabolism in health and disease

Wu, D., Zhang, K., Khan, F. A., Pandupuspitasari, N. S., Guan, K., Sun, F., & Huang, C. (2024) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2024.129607 · Cited by 35

Hypoxia-induced TREM1 promotes mesenchymal-like states of glioma stem cells via alternatively activating tumor-associated macrophages

Dong, M., Zhang, X., Peng, P., Chen, Z., Zhang, Y., Wan, L., Wang, X., Liu, G., Guo, Y., Xiao, Q., et al. (2024) · Cancer Letters · doi:10.1016/j.canlet.2024.216801 · Cited by 33

Multi-omics reveals immune response and metabolic profiles during high-altitude mountaineering

Yin, J., Lv, J., Yang, S., Wang, Y., Huang, Z., Wang, X., Hou, G., Zhou, W., Liu, Y., Wang, W., et al. (2024) · Cell Reports · doi:10.1016/j.celrep.2024.115134 · Cited by 36

The regulation of cell metabolism by hypoxia and hypercapnia

Reddan, B., & Cummins, E. P. (2025) · Journal of Biological Chemistry · doi:10.1016/j.jbc.2025.108252 · Cited by 34

Biological pathways and mechanisms linking COPD and cardiovascular disease

Ragnoli, B., Chiazza, F., Tarsi, G., & Malerba, M. (2025) · Therapeutic Advances in Chronic Disease · doi:10.1177/20406223251314286 · Cited by 34

Aberrant Notch-signaling promotes tumor angiogenesis in esophageal squamous-cell carcinoma

Li, C., Wu, P., Xie, X., Chen, X., Chen, L., Zhu, L., Xuan, Z., Liu, T., Tan, W., Zhang, S., et al. (2025) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-025-02309-5 · Cited by 35

Nuclear hormone receptor NHR-49 acts in parallel with HIF-1 to promote hypoxia adaptation in Caenorhabditis elegans

Doering, K. R. S., Cheng, X., Milburn, L. J., Ratnappan, R., Ghazi, A., Miller, D. L., & Taubert, S. (2022) · eLife · doi:10.7554/elife.67911 · Cited by 34

A light-driven nanopipette ion pump for probing subcellular oxygen levels

Yu, S.-Y., Liu, Y., Dong, H., Xu, Y., Hu, J., Lin, P., Zhao, W., Jiang, D., Chen, H., & Xu, J. (2023) · Device · doi:10.1016/j.device.2023.100001 · Cited by 33

Hypoxia-Inducible Factor and Oxidative Stress in Tendon Degeneration: A Molecular Perspective

Shahid, H., Morya, V. K., Oh, J.-U., Kim, J. H., & Noh, K.-C. (2024) · Antioxidants · doi:10.3390/antiox13010086 · Cited by 33

Hypoxic tumor microenvironment: Destroyer of natural killer cell function

Zhang, Y., Guo, F., & Wang, Y. (2024) · Chinese Journal of Cancer Research · doi:10.21147/j.issn.1000-9604.2024.02.04 · Cited by 32

Supramolecular discrimination and diagnosis-guided treatment of intracellular bacteria

Tian, J., Huang, S., Wang, Z.-H., Li, J., Song, X., Jiang, Z.-T., Shi, B.-S., Zhao, Y., Zhang, H., Wang, K., et al. (2025) · Nature Communications · doi:10.1038/s41467-025-56308-9 · Cited by 32

Exposure to hypoxia causes stress erythropoiesis and downregulates immune response genes in spleen of mice

Wang, H., Liu, D., Song, P., Jiang, F., Chi, X., & Zhang, T. (2021) · BMC Genomics · doi:10.1186/s12864-021-07731-x · Cited by 34

Oxygen enhances antiviral innate immunity through maintenance of EGLN1-catalyzed proline hydroxylation of IRF3

Liu, X., Tang, J., Wang, Z., Zhu, C., Deng, H., Sun, X., Yu, G., Rong, F., Chen, X., Liao, Q., et al. (2024) · Nature Communications · doi:10.1038/s41467-024-47814-3 · Cited by 33

Hypoxia and aging: molecular mechanisms, diseases, and therapeutic targets

Nisar, A., Khan, S., Li, W., Hu, L., Samarawickrama, P. N., Gold, N. M., Zi, M., Mehmood, S. A., Miao, J., & He, Y. (2024) · MedComm · doi:10.1002/mco2.786 · Cited by 33

Genome-wide CRISPR/Cas9 deletion screen defines mitochondrial gene essentiality and identifies routes for tumour cell viability in hypoxia

Thomas, L. W., Esposito, C., Morgan, R., Price, S., Young, J., Williams, S. P., Maddalena, L. A., McDermott, U., & Ashcroft, M. A. (2021) · Communications Biology · doi:10.1038/s42003-021-02098-x · Cited by 31

Hypoxia-inducible factor 1α induces osteo/odontoblast differentiation of human dental pulp stem cells via Wnt/β-catenin transcriptional cofactor BCL9

Orikasa, S., Kawashima, N., Tazawa, K., Hashimoto, K., Nara, K., Noda, S., Fujii, M., Akiyama, T., & Okiji, T. (2022) · Scientific Reports · doi:10.1038/s41598-021-04453-8 · Cited by 31

Noncoding RNAs as sensors of tumor microenvironmental stress

Lv, Y., Lv, Y., Wang, Z., Yuan, K., & Zeng, Y. (2022) · Journal of Experimental & Clinical Cancer Research · doi:10.1186/s13046-022-02433-y · Cited by 31

A Carbonic Anhydrase IX/SLC1A5 Axis Regulates Glutamine Metabolism Dependent Ferroptosis in Hypoxic Tumor Cells

Venkateswaran, G., McDonald, P. C., Chafe, S. C., Brown, W. S., Gerbec, Z. J., Awrey, S. J., Parker, S. J., & Dedhar, S. (2022) · Molecular Cancer Therapeutics · doi:10.1158/1535-7163.mct-23-0041 · Cited by 31

A mitochondrial EglN1‐AMPKα axis drives breast cancer progression by enhancing metabolic adaptation to hypoxic stress

Jiang, W., Zhang, M., Gao, C., Yan, C., Gao, R., He, Z., Wei, X. L., Xiong, J., Ruan, Z.-L., Yang, Q., et al. (2023) · The EMBO Journal · doi:10.15252/embj.2023113743 · Cited by 30

Hypoxia as a Target for Combination with Transarterial Chemoembolization in Hepatocellular Carcinoma

Wang, Z., Li, Q., & Liang, B. (2024) · Pharmaceuticals · doi:10.3390/ph17081057 · Cited by 30

The molecular mosaic of regulated cell death in the cardiovascular system

Martens, M. D., Karch, J. M., & Gordon, J. W. (2021) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2021.166297 · Cited by 31

Adipocyte HIF2α functions as a thermostat via PKA Cα regulation in beige adipocytes

Han, J. S., Jeon, Y. G., Oh, M., Lee, G., Nahmgoong, H., Han, S. M., Choi, J., Kim, Y. Y., Shin, K. C., Kim, J., et al. (2022) · Nature Communications · doi:10.1038/s41467-022-30925-0 · Cited by 30

Reoxygenation Modulates the Adverse Effects of Hypoxia on Wound Repair

Bai, Q., Gao, Q., Hu, F., Zheng, C., Sun, N., Chen, W., Liu, J., Zhang, Y., Wu, X., & Lu, T. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms232415832 · Cited by 29

Mechanism and regulation of iron absorption throughout the life cycle

Qiu, L., Frazer, D. M., Hu, M., Song, R., Liu, X., Qin, X., Ma, J., Zhou, J., Tan, Z., Ren, F., et al. (2025) · Journal of Advanced Research · doi:10.1016/j.jare.2025.01.002 · Cited by 33

Redox imbalance and hypoxia‐inducible factors: a multifaceted crosstalk

Ravi, R., & Singh, J. (2025) · FEBS Journal · doi:10.1111/febs.70013 · Cited by 29

Selective inhibition of carbonic anhydrase IX and XII by coumarin and psoralen derivatives

Meleddu, R., Deplano, S., Maccioni, E., Ortuso, F., Cottiglia, F., Secci, D., Onali, A., Sanna, E., Angeli, A., Angius, R., et al. (2021) · Journal of Enzyme Inhibition and Medicinal Chemistry · doi:10.1080/14756366.2021.1887171 · Cited by 29

Intrinsic Mechanisms Underlying Hypoxia-Tolerant Mitochondrial Phenotype During Hypoxia-Reoxygenation Stress in a Marine Facultative Anaerobe, the Blue Mussel Mytilus edulis

Sokolov, E. P., Adzigbli, L., Markert, S., Bundgaard, A., Fago, A., Becher, D., Hirschfeld, C., & Sokolova, I. M. (2021) · Frontiers in Marine Science · doi:10.3389/fmars.2021.773734 · Cited by 31

Metabolic response provides insights into the mechanism of adaption to hypoxia in largemouth bass (Micropterus salmoides) under intermittent hypoxic conditions

Zhao, L., Yan, H., Cheng, L., He, K., Liu, Q., Luo, J., Luo, W., Zhang, X., Yan, T., Du, Z., et al. (2022) · Ecotoxicology and Environmental Safety · doi:10.1016/j.ecoenv.2022.113957 · Cited by 29

Effects of hypoxia-inducible factor-prolyl hydroxylase inhibitors vs. erythropoiesis-stimulating agents on iron metabolism in non-dialysis-dependent anemic patients with CKD: A network meta-analysis

Yang, J., Xing, J., Zhu, X., Xie, X., Wang, L., & Zhang, X. (2023) · Frontiers in Endocrinology · doi:10.3389/fendo.2023.1131516 · Cited by 29

Activation of HIF-1α C-terminal transactivation domain protects against hypoxia-induced kidney injury through hexokinase 2-mediated mitophagy

Li, Z., Ding, L., Ma, R., Zhang, Y., Zhang, Y., Ni, W., Tang, T., Wang, G., Wang, B., Lv, L., et al. (2023) · Cell Death and Disease · doi:10.1038/s41419-023-05854-5 · Cited by 30

Reprogramming the immunosuppressive tumor microenvironment: exploiting angiogenesis and thrombosis to enhance immunotherapy

Shafqat, A., Omer, M. H., Ahmed, E. N., Mushtaq, A. H., Ijaz, E., Ahmed, Z., AlKattan, K. M., & Yaqinuddin, A. (2023) · Frontiers in Immunology · doi:10.3389/fimmu.2023.1200941 · Cited by 32

Longitudinal dynamics of the tumor hypoxia response: From enzyme activity to biological phenotype

Lee, S. C.-E. S., Pyo, A. H. A., & Koritzinsky, M. (2023) · Science Advances · doi:10.1126/sciadv.adj6409 · Cited by 28

Whole-Body and Whole-Organ 3D Imaging of Hypoxia Using an Activatable Covalent Fluorescent Probe Compatible with Tissue Clearing

Sakamoto, D. M., Tamura, I., Yi, B., Hasegawa, S., Saito, Y., Yamada, N., Takakusagi, Y., Kubota, S. I., Kobayashi, M., Harada, H., et al. (2024) · ACS Nano · doi:10.1021/acsnano.3c12716 · Cited by 28

Research progress on the role of reactive oxygen species in the initiation, development and treatment of breast cancer

Zhong, J., & Tang, Y. J. (2024) · Progress in Biophysics and Molecular Biology · doi:10.1016/j.pbiomolbio.2024.02.005 · Cited by 29

Hypoxia-inducible factor and cellular senescence in pulmonary aging and disease

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Decreased lymphatic HIF-2α accentuates lymphatic remodeling in lymphedema

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