Cellular adaptation to hypoxia through hypoxia inducible factors and beyond

Repertoires of Autophagy in the Pathogenesis of Ocular Diseases

Li, Y., Jiang, Q. L., Cao, G.-F., Yao, J., & Yan, B. (2015) · Cellular Physiology and Biochemistry · doi:10.1159/000373980 · Cited by 16,351

A role for mitochondria in nlrp3 inflammasome activation

Zhou, R., Yazdi, A. S., Menu, P., & Tschopp, J. (2011) · Nature · doi:10.1038/nature09663 · Cited by 5,602

Control of inositol 1,4,5-trisphosphate-induced Ca2+ release by cytosolic Ca2+

Bootman, M. D., Missiaen, L., Parys, J. B., SMEDT, H. D., & Casteels, R. (1995) · Biochemical Journal · doi:10.1042/bj3060445 · Cited by 5,131

Targeting Hypoxia-Inducible Factors for the Treatment of Anemia in Chronic Kidney Disease Patients

Locatelli, F., Fishbane, S. N., Block, G. A., & Macdougall, I. C. (2017) · American Journal of Nephrology · doi:10.1159/000455166 · Cited by 4,836

Mitochondria, Oxidants, and Aging

Balaban, R. S., Nemoto, S., & Finkel, T. (2005) · Cell · doi:10.1016/j.cell.2005.02.001 · Cited by 4,388

The unfolded protein response: controlling cell fate decisions under ER stress and beyond

Hetz, C. A. (2012) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm3270 · Cited by 4,223

XBP1 mRNA Is Induced by ATF6 and Spliced by IRE1 in Response to ER Stress to Produce a Highly Active Transcription Factor

Yoshida, H., Matsui, T., Yamamoto, A., Okada, T., & Mori, K. (2001) · Cell · doi:10.1016/s0092-8674(01)00611-0 · Cited by 4,054

HIF-1-mediated expression of pyruvate dehydrogenase kinase: A metabolic switch required for cellular adaptation to hypoxia

Kim, J.-W., Tchernyshyov, I., Semenza, G. L., & Dang, C. V. (2006) · Cell Metabolism · doi:10.1016/j.cmet.2006.02.002 · Cited by 3,905

Mutation of the mouse klotho gene leads to a syndrome resembling ageing

Kuro-o, M., Matsumura, Y., Aizawa, H., Kawaguchi, H., Suga, T., Utsugi, T., Ohyama, Y., Kurabayashi, M., Kaname, T., Kume, E., et al. (1997) · Nature · doi:10.1038/36285 · Cited by 3,837

A Nitroreductase‐Activatable Metabolic Reporter for Covalent Labeling of Pathological Hypoxic Cells in Tumorigenesis

Wang, Z., Lau, J. W., Liu, S., Ren, Z., Gong, Z., Liu, X., & Xing, B. (2024) · Angewandte Chemie International Edition · doi:10.1002/anie.202411636 · Cited by 17

Nicotinamide Mononucleotide (NMN) Ameliorates Free Fatty Acid-Induced Pancreatic β-Cell Dysfunction via the NAD+/AMPK/SIRT1/HIF-1α Pathway

Wang, Y., Liu, S., Ying, L., Zhang, K., Li, H., Liang, N., Xiao, L., & Luo, G. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms251910534 · Cited by 18

Placental Adaptation to Hypoxia: The Case of High-Altitude Pregnancies

Ahrens, S., & Singer, D. (2025) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph22020214 · Cited by 19

Treatment with hypoxia‐mimetics protects cultured rat Schwann cells against oxidative stress‐induced cell death

David, B. T., Curtin, J. J., Brown, J. L., Coutts, D. J. C., Boles, N. C., & Hill, C. E. (2021) · Glia · doi:10.1002/glia.24019 · Cited by 17

Targeting Hypoxia: Revival of Old Remedies

Vilaplana‐Lopera, N., Besh, M., & Moon, E. J. (2021) · Biomolecules · doi:10.3390/biom11111604 · Cited by 17

iASPP is essential for HIF-1α stabilization to promote angiogenesis and glycolysis via attenuating VHL-mediated protein degradation

Zhao, D. H., Zheng, S., Wang, X., Liu, H., Zhao, K., Li, L., & Hu, Y. (2022) · Oncogene · doi:10.1038/s41388-022-02234-9 · Cited by 18

Targeting Metabolic Reprogramming of T-Cells for Enhanced Anti-Tumor Response

Dabi, Y. T., Henok, A., Degechisa, S. T., & Gizaw, S. T. (2022) · Biologics · doi:10.2147/btt.s365490 · Cited by 17

Isoform-resolved mRNA profiling of ribosome load defines interplay of HIF and mTOR dysregulation in kidney cancer

Sugimoto, Y., & Ratcliffe, P. J. (2022) · Nature Structural & Molecular Biology · doi:10.1038/s41594-022-00819-2 · Cited by 18

Long-read Ribo-STAMP simultaneously measures transcription and translation with isoform resolutionPreprint

Jagannatha, P., Tankka, A. T., Lorenz, D. A., Yu, T., Yee, B. A., Brannan, K. W., Zhou, C. J., Underwood, J. G., & Yeo, G. W.-M. (2024) · Genome Research · doi:10.1101/gr.279176.124 · Cited by 18

An active peptide from yak inhibits hypoxia-induced lung injury via suppressing VEGF/MAPK/inflammatory signaling

Yang, F., He, Z., Chu, Z., Li, W., Qu, G., Lu, H., Tang, Y., Sun, S., Luo, Z., & Luo, F. (2024) · Redox Biology · doi:10.1016/j.redox.2024.103252 · Cited by 16

Cardiomyocytes in Hypoxia: Cellular Responses and Implications for Cell-Based Cardiac Regenerative Therapies

Dwyer, K. D., Snyder, C. A., & Coulombe, K. L. K. (2025) · Bioengineering · doi:10.3390/bioengineering12020154 · Cited by 16

Intestinal oxygen and microbiota crosstalk: implications for pathogenesis of gastrointestinal diseases and emerging therapeutic strategies

Shang, T., Zhang, R., Liu, Y., & Shi, S. (2025) · Gut Pathogens · doi:10.1186/s13099-025-00783-4 · Cited by 16

Ultrasound-triggered piezocatalytic MOF(Hf)-Pt nanozymes for efficient ROS scavenging in the treatment of osteoarthritis

Yao, Y., Gao, Z., Pan, Z., Zhong, Y., Qin, L., Zhao, K., Liu, S., Zhang, S., Han, H., Yin, F., et al. (2025) · Chemical Engineering Journal · doi:10.1016/j.cej.2025.167229 · Cited by 16

Nanobooster-encapsulated hybrid RNA as anti-tumor viral mimicry

Liu, C., Zhou, Y., Ji, X., Xie, H., Hu, X., Yin, M., Chen, N., Fan, C., & Song, H. (2021) · Nano Today · doi:10.1016/j.nantod.2021.101211 · Cited by 16

Proteomic and Morphological Profiling of Mice Ocular Tissue During High-altitude Acclimatization Process: An Animal Study at Lhasa

Hou, J., Zheng, D., Wen, X., Xiao, W., Han, F., Lang, H., Xiong, S., Jiang, W., Hu, Y., He, M., et al. (2022) · Journal of Inflammation Research · doi:10.2147/jir.s361174 · Cited by 16

Hydroxytyrosol Alleviated Hypoxia‐Mediated PC12 Cell Damage through Activating PI3K/AKT/mTOR‐HIF‐1α Signaling

Li, X., Tian, X., Liu, T., Li, M., Wang, W., Wang, P., & Guo, Z. (2022) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2022/8673728 · Cited by 16

NIR diagnostic imaging of triple-negative breast cancer and its lymph node metastasis for high-efficiency hypoxia-activated multimodal therapy

Pan, Y., Liu, L., He, Y., Ye, L., Zhao, X., Hu, Z., Mou, X., & Cai, Y. (2023) · Journal of Nanobiotechnology · doi:10.1186/s12951-023-02010-1 · Cited by 16

miRNA-21-5p is an important contributor to the promotion of injured peripheral nerve regeneration using hypoxia-pretreated bone marrow–derived neural crest cells

Meng, C., Hu, J., Yu, Y., Li, X.-L., Sun, X., Wang, L., Wu, X., Zhu, L.-J., Yang, X., He, Q., et al. (2023) · Neural Regeneration Research · doi:10.4103/1673-5374.390956 · Cited by 17

Roles of HIF-1α signaling in Mycobacterium tuberculosis infection: New targets for anti-TB therapeutics?

Li, C., Wang, J., Xu, J., Pi, J., & Zheng, B. (2024) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2024.149920 · Cited by 18

Divergent landscapes of A-to-I editing in postmortem and living human brain

Santos, M. R. D. L., Kopell, B. H., Grice, A. B., Ganesh, G., Yang, A., Amini, P., Liharska, L. E., Vornholt, E., Fullard, J. F., Dong, P., et al. (2024) · Nature Communications · doi:10.1038/s41467-024-49268-z · Cited by 16

Mitochondria to plasma membrane redox signaling is essential for fatty acid β-oxidation-driven insulin secretion

Jabůrek, M., Klöppel, E., Průchová, P., Mozheitová, O., Tauber, J. A., Engstová, H., & Ježek, P. (2024) · Redox Biology · doi:10.1016/j.redox.2024.103283 · Cited by 16

Harnessing the Power of Photosynthesis: from Current Engineering Strategies to Cell Factory Applications

Shi, Y., Wang, Z., Zhao, X., Li, Z., Zheng, J., & Liu, J. (2025) · Small Methods · doi:10.1002/smtd.202402147 · Cited by 16

The multifaceted functions of RNA helicases in the adaptive cellular response to hypoxia: From mechanisms to therapeutics

Wang, Y., Li, G., Deng, M., Liu, X., Huang, W., Zhang, Y., Liu, M., & Chen, Y. (2020) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2020.107783 · Cited by 16

An overview of the developments and potential applications of 68Ga-labelled PET/CT hypoxia imaging

Bresser, P. L., Vorster, M., & Sathekge, M. M. (2021) · Annals of Nuclear Medicine · doi:10.1007/s12149-020-01563-7 · Cited by 16

Mechanism Analysis of Antiangiogenic d -Isofloridoside from Marine Edible Red algae Laurencia undulata in HUVEC and HT1080 cell

Yang, S., Xiao, Z., Lin, L., Tang, Y., Hong, P., Sun, S., Zhou, C., & Qian, Z. (2021) · Journal of Agricultural and Food Chemistry · doi:10.1021/acs.jafc.1c05007 · Cited by 16

Comparing the Secretomes of Chemorefractory and Chemoresistant Ovarian Cancer Cell Populations

Lee, A. H., Peña, C. M., & Dawson, M. (2022) · Cancers · doi:10.3390/cancers14061418 · Cited by 17

Plant growth-promoting effects and possible mechanisms of a plant endophytic fungus Aureobasidium sp. JRF1

Jiang, Z., Peng, F., Yu, J., & Li, Q. (2025) · Plant Physiology and Biochemistry · doi:10.1016/j.plaphy.2025.109724 · Cited by 15

Research progress on NAT10-mediated acetylation in normal development and disease

Qin, D., Liu, Q., Ma, X., Wang, R., Lu, T., Yang, Y., Tang, Z., & Zhu, Y. (2025) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2025.1623276 · Cited by 15

Stimuli‐Responsive Supramolecular Biomaterials for Cancer Theranostics

Hu, W., Ye, B., Yu, G., Huang, F., & Mao, Z. (2026) · Advanced Science · doi:10.1002/advs.202515860 · Cited by 17

Increased M2 Isoform of Pyruvate Kinase in Fibroblasts Contributes to the Growth, Aggressiveness, and Osteoclastogenesis of Odontogenic Keratocysts

Zou, Y., Wang, R., Zhao, J., Cai, Y., & Zhong, W. (2021) · American Journal Of Pathology · doi:10.1016/j.ajpath.2021.02.010 · Cited by 15

Hypoxia-inducible factor expression is related to apoptosis and cartilage degradation in temporomandibular joint osteoarthritis

Zhang, J., Hu, Y., Wang, Z., Wu, X., Yang, C., & Yang, H. (2022) · BMC Musculoskeletal Disorders · doi:10.1186/s12891-022-05544-x · Cited by 15

Advances in Understanding of Metabolism of B-Cell Lymphoma: Implications for Therapy

Kľučková, K., D’Avola, A., & Riches, J. C. (2022) · Cancers · doi:10.3390/cancers14225552 · Cited by 16

Hypoxia as a regulator of tumor stroma and metastasis

Lee, K. E. (2022) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.00158.2022 · Cited by 17

Hypoxic regulation of extracellular vesicles: Implications for cancer therapy

Yoo, S., Choi, S., Kim, I., & Kim, I. (2023) · Journal of Controlled Release · doi:10.1016/j.jconrel.2023.09.034 · Cited by 15

Global lipid remodelling by hypoxia aggravates migratory potential in pancreatic cancer while maintaining plasma membrane homeostasis

Agarwala, P. K., Nie, S., Reid, G. E., & Kapoor, S. (2023) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · doi:10.1016/j.bbalip.2023.159398 · Cited by 15

Role of Microenvironmental Components in Head and Neck Squamous Cell Carcinoma

Jumaniyazova, E. D., Lokhonina, А. V., Dzhalilova, D. S., Kosyreva, A. M., & Fatkhudinov, T. (2023) · Journal of Personalized Medicine · doi:10.3390/jpm13111616 · Cited by 19

Mint3-depletion-induced energy stress sensitizes triple-negative breast cancer to chemotherapy via HSF1 inactivation

Tanaka, N., Okada, H., Yamaguchi, K., Seki, M., Matsubara, D., Gotoh, N., Suzuki, Y., Furukawa, Y., Yamashita, T., Inoue, J., et al. (2023) · Cell Death and Disease · doi:10.1038/s41419-023-06352-4 · Cited by 15

The Emerging Role of Deubiquitinases in Radiosensitivity

Cao, X., Yan, Z., Chen, Z., Ge, Y., Hu, X., Peng, F., Huang, W., Zhang, P., Sun, R., Chen, J., et al. (2023) · International Journal of Radiation Oncology*Biology*Physics · doi:10.1016/j.ijrobp.2023.12.003 · Cited by 15

Impact of hypoxia on glucose metabolism and hypoxia signaling pathways in juvenile horseshoe crabs Tachypleus tridentatus

Jiang, L., Shang, Y., Shi, Y., Ma, X., Khalid, M. S., Huang, M., Fang, J. K., Wang, Y., Tan, K., & Hu, M. (2024) · Marine Environmental Research · doi:10.1016/j.marenvres.2024.106467 · Cited by 15

Non-coding RNAs, metabolic stress and adaptive mechanisms in cancer

Liu, X., Feng, S., Zhang, X. D., Li, J., Zhang, K., Wu, M., & Thorne, R. F. (2020) · Cancer Letters · doi:10.1016/j.canlet.2020.06.024 · Cited by 15

Metabolic adaptations to hypoxia in the neonatal mouse forebrain can occur independently of the transporters SLC7A5 and SLC3A2

Fitzgerald, E., Roberts, J., Tennant, D. A., Boardman, J. P., & Drake, A. J. (2021) · Scientific Reports · doi:10.1038/s41598-021-88757-9 · Cited by 15

Redox and Inflammatory Signaling, the Unfolded Protein Response, and the Pathogenesis of Pulmonary Hypertension.

Katseff, A. S., Alhawaj, R., & Wolin, M. (2021) · Advances in Experimental Medicine and Biology · doi:10.1007/978-3-030-68748-9_17 · Cited by 14

Pixantrone Sensitizes Gram-Negative Pathogens to Rifampin

She, P., Li, Z., Li, Y., Liu, S., Li, L., Yang, Y., Zhou, L., & Wu, Y. C. (2022) · Microbiology Spectrum · doi:10.1128/spectrum.02114-22 · Cited by 15

Advances in Molecular Pathology of Obstructive Sleep Apnea

Zhang, M., Lu, Y., Sheng, L., Han, X., Yu, L., Zhang, W., Liu, S., & Liu, Y. (2022) · Molecules · doi:10.3390/molecules27238422 · Cited by 17

Cell line development for continuous high cell density biomanufacturing: Exploiting hypoxia for improved productivity

Zeh, N., Schlossbauer, P., Raab, N., Klingler, F., Handrick, R., & Otte, K. (2021) · Metabolic Engineering Communications · doi:10.1016/j.mec.2021.e00181 · Cited by 15

RNF20 links the DNA damage response and metabolic rewiring in lung cancer through HIF1α

Liu, H., Tang, Y., Singh, A., Vong, J. S. L., Cordero, J., Mathes, A., Gao, R., Jia, Y., Garvalov, B. K., Acker, T., et al. (2025) · Nature Communications · doi:10.1038/s41467-025-60223-4 · Cited by 14

Decoding inflammatory signaling networks: From molecular mechanisms to therapeutic targets

Satapathy, T., Patel, N. T., Sahu, P., & Satapathy, A. (2025) · Advances in Biomarker Sciences and Technology · doi:10.1016/j.abst.2025.07.002 · Cited by 14

How lactate and lactylation shape the immunity system in atherosclerosis (Review)

Xiong, Y., Zhou, J., Wang, J., & Huang, H. (2025) · International Journal of Molecular Medicine · doi:10.3892/ijmm.2025.5604 · Cited by 14

Harnessing Cuproptosis resistance to advance cancer therapeutics

Li, Z., Wu, T.-F., & Zhi-Jun, S. (2026) · APOPTOSIS · doi:10.1007/s10495-026-02266-6 · Cited by 14

Advanced Drug Delivery Strategies for Overcoming Biological Barriers: Tumor Microenvironment and Blood–Brain Barrier

Lei, Y., Xiao, T., Hu, X., & Lin, H. (2026) · Drugs in R&D · doi:10.1007/s40268-026-00538-9 · Cited by 14

Oxygen nanocarrier broke the hypoxia trap of solid tumors and rescued transfection efficiency for gene therapy

Qin, B., Jiang, M., Li, X., Shi, Y., Zhang, J., Luo, Z., Luo, L., Lu, Y., Liu, X., Wang, S., et al. (2021) · Journal of Nanobiotechnology · doi:10.1186/s12951-021-01144-4 · Cited by 14

Investigations into photoreceptor energy metabolism during experimental retinal detachment

Chidlow, G., Chan, W. O., Wood, J. P. M., & Casson, R. J. (2022) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2022.1036834 · Cited by 14

3, 3'-diindolylmethane, a natural aryl hydrocarbon receptor agonist, alleviates ulcerative colitis by enhancing “glycolysis-lactate-STAT3″ and TIP60 signals-mediated Treg differentiation

Liu, S., Yan, W., Lv, Q., Yang, L., Miao, Y., Hu, Y., & Wei, Z. (2023) · Molecular Immunology · doi:10.1016/j.molimm.2023.09.009 · Cited by 14

Hypoxia-mimetic by CoCl2 increases SLC7A5 expression in breast cancer cells in vitro

Canhasi, L., Tina, E., & Eremo, A. G. (2023) · BMC Research Notes · doi:10.1186/s13104-023-06650-2 · Cited by 14

MicroRNA ‐210 mediates hypoxia‐induced pulmonary hypertension by targeting mitochondrial bioenergetics and mtROS flux

Ahmed, A. S. I., Blood, A. B., & Zhang, L. (2024) · Acta Physiologica · doi:10.1111/apha.14212 · Cited by 14

Oxygen metabolism abnormalities and high-altitude cerebral edema

Li, Z., Zhang, J., Zhang, X., Jin, Q., Zheng, X., Mo, L., & Da, Z. (2025) · Frontiers in Immunology · doi:10.3389/fimmu.2025.1555910 · Cited by 14

An mRNA-display derived cyclic peptide scaffold reveals the substrate binding interactions of an N-terminal cysteine oxidase

Jiramongkol, Y., Patel, K., Johansen‐Leete, J., Maxwell, J. W. C., Chang, Y., Du, J. J., Passioura, T., Cook, K. M., Payne, R. J., & White, M. D. (2025) · Nature Communications · doi:10.1038/s41467-025-59960-3 · Cited by 14

Embryonic developmental arrest in the annual killifish Austrolebias charrua: A proteomic approach to diapause III

Chalar, C., Clivio, G., Montagne, J., Costábile, A., Lima, A. E., Papa, N. G., Berois, N., & Arezo, M. J. (2021) · PLoS ONE · doi:10.1371/journal.pone.0251820 · Cited by 14

Does Normobaric Hypoxic Resistance Training Confer Benefit over Normoxic Training in Athletes? A Narrative Review

Deldicque, L. (2022) · Journal of Science in Sport and Exercise · doi:10.1007/s42978-021-00159-5 · Cited by 14

Hypoxia and Hypoxia-Inducible Factors in Lymphedema

Jiang, X., Tian, W., Kim, D., McQuiston, A. S., Vinh, R., Rockson, S. G., Semenza, G. L., & Nicolls, M. R. (2022) · Frontiers in Pharmacology · doi:10.3389/fphar.2022.851057 · Cited by 16

Decellularized extracellular matrix-based scaffold and hypoxic priming: A promising combination to improve the phenotype of degenerate intervertebral disc cells

Penolazzi, L., Lambertini, E., D’Agostino, S., Pozzobon, M., Notarangelo, M. P., Greco, P., BONIS, P. D., Nastruzzi, C., & Piva, R. (2022) · Life Sciences · doi:10.1016/j.lfs.2022.120623 · Cited by 14

Enhancing autophagy and energy metabolism in the meniscus can delay the occurrence of PTOA in ACLT rat

Zhu, H., Liu, H., Chen, X., Xu, X., Zhang, S., & Xie, D. (2022) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2022.971736 · Cited by 14

In-hospital mortality and SpO2 incritical care patients with cerebral injury: data from the MIMIC‑IV Database

Yin, H., Yang, R., Xin, Y., Jiang, T., & Zhong, D. (2022) · BMC Anesthesiology · doi:10.1186/s12871-022-01933-w · Cited by 14

NR4A1 Aggravates Myocardial Ischaemia–Reperfusion Injury by Inhibiting OPA1-Mediated Mitochondrial Fusion

Li, M., Hu, Y., Zhou, H., & Chen, Y. (2023) · Journal of Cardiovascular Translational Research · doi:10.1007/s12265-023-10396-4 · Cited by 14

Limosilactobacillus reuteri ZY15 Alleviates Intestinal Inflammation and Barrier Dysfunction via AKT/mTOR/HIF-1α/RORγt/IL-17 Signaling and the Gut Microbiota in ETEC K88-Challenged Mice

Xu, X., Zhang, H., Meng, K., Cai, H., Liu, W., Song, L., Zhang, Z., Zhu, Q., Han, X., Han, Y., et al. (2025) · Antioxidants · doi:10.3390/antiox14010058 · Cited by 14

Hypoxia Alleviation Enhances the Efficacy of 5‐Fluorouracil in Hypertrophic Scar Therapy via an Oxygen‐Popping Microneedle System

Fu, J., Yu, W., Mu, Y., Qian, X., Li, X., Sun, K., Wang, Y., & Ji, J. (2025) · Advanced Functional Materials · doi:10.1002/adfm.202422678 · Cited by 13

Hypoxia-Induced Changes in Endothelial Cell Phenotype and Function

Tóth, A., & Jeney, V. (2025) · Antioxidants and Redox Signaling · doi:10.1089/ars.2025.1022 · Cited by 14

Excitatory amino acid transporters support mast cell degranulation via α-KG-mediated methylation of Spp1

Gan, Z., Xia, Y., Bin, P., Zhao, M., Zhou, Y., Liu, B., & Ren, W. (2026) · Cellular and Molecular Immunology · doi:10.1038/s41423-025-01375-7 · Cited by 13

Red light photobiomodulation rescues murine brain mitochondrial respiration after acute hypobaric hypoxia

Pchelin, P. V., Shkarupa, D., Smetanina, N., Grigorieva, T., Дмитриевич, Л. Р., Schelchkova, N. A., Machneva, T., & Петровна, Б. А. (2022) · Journal of Photochemistry and Photobiology B Biology · doi:10.1016/j.jphotobiol.2022.112643 · Cited by 13

3-Bromopyruvate-Loaded Ti3C2 MXene/Cu2O Nanosheets for Photoacoustic Imaging-Guided and Hypoxia-Relieving Enhanced Photothermal/Chemodynamic Therapy

Wang, Z., Li, H., She, W., Zhang, X., Liu, Y., Liu, Y., & Jiang, P. (2023) · Analytical Chemistry · doi:10.1021/acs.analchem.2c04953 · Cited by 13

Live-cell imaging-based dynamic vascular formation assay for antivascular drug evaluation and screening

Li, Z., Zhang, H., Sun, Y., Feng, Z., Cui, B., Han, J., Li, Y., Liu, H., & Sun, T. (2023) · iScience · doi:10.1016/j.isci.2023.106721 · Cited by 13

eIF4EHP promotes Ldh mRNA translation in and fruit fly adaptation to hypoxia

Liang, M., Hody, C., Yammine, V., Soin, R., Sun, Y., Lin, X., Tian, X., Meurs, R., Perdrau, C., Delacourt, N., et al. (2023) · EMBO Reports · doi:10.15252/embr.202256460 · Cited by 13

HIF1α-dependent hypoxia response in myeloid cells requires IRE1α

Mawambo, G., Oubaha, M., Ichiyama, Y., Blot, G., Crespo‐Garcia, S., Dejda, A., Binet, F., Diaz-Marin, R., Sawchyn, C., Sergeev, M., et al. (2023) · Journal of Neuroinflammation · doi:10.1186/s12974-023-02793-y · Cited by 13

microRNAs: critical targets for treating rheumatoid arthritis angiogenesis

Zhao, L., Wu, Q., Long, Y., Qu, Q.-R., Qi, F., Liu, L., Zhang, L. N., & Ai, K. (2023) · Journal of drug targeting · doi:10.1080/1061186x.2023.2284097 · Cited by 13

Enhancing HIF-1α–P2X2 signaling in dorsal raphe serotonergic neurons promotes psychological resilience

Zhang, Y., Pan, Y., Zheng, W.-Y., Li, H.-Y., Zhu, M., yang, W.-J. O., Qian, Y., Turecki, G., Mechawar, N., & Zhu, X. (2023) · Redox Biology · doi:10.1016/j.redox.2023.103005 · Cited by 13

Protein thermal sensing regulates physiological amyloid aggregation

Marijan, D., Momchilova, E. A., Burns, D., Chandhok, S., Zapf, R., Wille, H., Potoyan, D. A., & Audas, T. E. (2024) · Nature Communications · doi:10.1038/s41467-024-45536-0 · Cited by 13

Unveiling the link: exploring muscle oxygen saturation in fibromyalgia and its implications for symptomatology and therapeutic strategies

Rubio-Zarapuz, A., Parraça, J. A., Tornero-Aguilera, J. F., & Clemente‐Suárez, V. J. (2024) · Medical Gas Research · doi:10.4103/mgr.medgasres-d-24-00013 · Cited by 13

Roles of hypoxia-inducible factor-prolyl hydroxylases in aging and disease

Galkin, F., Pulous, F. E., Fu, Y., Zhang, M., Pun, F. W., Ren, F., & Zhavoronkov, A. A. (2024) · Ageing Research Reviews · doi:10.1016/j.arr.2024.102551 · Cited by 14

Low extracellular pH protects cancer cells from ammonia toxicity

Dravecka, M., Mikkola, I., Johansen, T., Seternes, O. M., & Mejlvang, J. (2025) · Cell Death Discovery · doi:10.1038/s41420-025-02440-w · Cited by 13

Improving cellular fitness of human stem cell-derived islets under hypoxia

Wang, X., Brielle, S., Kenty, J. H.-R., Korover, N., Bavli, D., Pop, R., & Melton, D. A. (2025) · Nature Communications · doi:10.1038/s41467-025-59924-7 · Cited by 14

Elevated trophoblastic Siglec6 contributes to the impairment of vascular endothelial cell functions by downregulating Wnt6/β-catenin signaling in preeclampsia

Guan, X., Yu, M., Wu, L., Chen, J., Tong, J., Wu, X., Yin, A., Xiao, T., Wang, B., Zhang, J. V., et al. (2022) · Archives of Biochemistry and Biophysics · doi:10.1016/j.abb.2022.109396 · Cited by 13

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MYC overrides HIF-1α to regulate proliferating primary cell metabolism in hypoxia

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The Effect of High-Altitude Hypoxia on Neuropsychiatric Functions

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Study of Transcriptomic Analysis of Yak (Bos grunniens) and Cattle (Bos taurus) Pulmonary Artery Smooth Muscle Cells under Oxygen Concentration Gradients and Differences in Their Lung Histology and Expression of Pyruvate Dehydrogenase Kinase 1-Related Factors

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Function and regulation of nitric oxide signaling in Drosophila

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Metabolic adaptation in epithelial ovarian cancer metastasis

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VHL suppresses UBE3B-mediated breast tumor growth and metastasis

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EBF1-COX4I2 signaling axis promotes a myofibroblast-like phenotype in cancer-associated fibroblasts (CAFs) and is associated with an immunosuppressive microenvironment

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SGLT2 Inhibitors and the Risk of Contrast-Associated Nephropathy Following Angiographic Intervention: Contradictory Concepts and Clinical Outcomes

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In Situ Oxygen Generation via a Platinum‐Based Wireless Nanopore Electrode for Single‐Cell Manipulation

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Cellular and Molecular Defenses Against Hypoxia

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Hypoxia Inducible Factor Pathway and Physiological Adaptation: A Cell Survival Pathway?

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Abstract IA017: Impact of oxygen and nutrient availability on sarcoma tumor neighborhood

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Molecular aspects of oxygen sensing in physiological adaptation to hypoxia

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