Spinal cord repair: advances in biology and technology

Microglia Sculpt Postnatal Neural Circuits in an Activity and Complement-Dependent Manner

Schafer, D. P., Lehrman, E. K., Kautzman, A. G., Koyama, R., Mardinly, A. R., Yamasaki, R., Ransohoff, R. M., Greenberg, M. E., Barres, B. A., & Stevens, B. (2012) · Neuron · doi:10.1016/j.neuron.2012.03.026 · Cited by 4,089

The Classical Complement Cascade Mediates CNS Synapse Elimination

Stevens, B., Allen, N. J., Vazquez, L. E., Howell, G. R., Christopherson, K. S., Nouri, N., Micheva, K. D., Mehalow, A. K., Huberman, A. D., Stafford, B., et al. (2007) · Cell · doi:10.1016/j.cell.2007.10.036 · Cited by 3,313

Reach and grasp by people with tetraplegia using a neurally controlled robotic arm

Hochberg, L. R., Bacher, D., Jarosiewicz, B., Masse, N. Y., Simeral, J. D., Vogel, J., Haddadin, S., Liu, J., Cash, S. S., van der Smagt, P., et al. (2012) · Nature · doi:10.1038/nature11076 · Cited by 2,719

Targeting Recovery: Priorities of the Spinal Cord-Injured Population

Anderson, K. D. (2004) · Journal of Neurotrauma · doi:10.1089/neu.2004.21.1371 · Cited by 2,094

Experience-dependent structural synaptic plasticity in the mammalian brain

Holtmaat, A., & Svoboda, K. (2009) · Nature Reviews Neuroscience · doi:10.1038/nrn2699 · Cited by 1,934

Astrocyte scar formation aids central nervous system axon regeneration

Anderson, M. A., Burda, J. E., Ren, Y., Ao, Y., O’Shea, T. M., Kawaguchi, R., Coppola, G., Khakh, B. S., Deming, T. J., & Sofroniew, M. V. (2016) · Nature · doi:10.1038/nature17623 · Cited by 1,851

High-performance neuroprosthetic control by an individual with tetraplegia

Collinger, J. L., Wodlinger, B., Downey, J. E., Wang, W., Tyler-Kabara, E. C., Weber, D. J., McMorland, A. J., Velliste, M., Boninger, M. L., & Schwartz, A. B. (2013) · The Lancet · doi:10.1016/s0140-6736(12)61816-9 · Cited by 1,848

Thrombospondins are astrocyte-secreted proteins that promote CNS synaptogenesis

Christopherson, K. S., Ullian, E. M., Stokes, C. C. A., Mullowney, C. E., Hell, J. W., Agah, A., Lawler, J., Mosher, D. F., Bornstein, P., & Barres, B. A. (2005) · Cell · doi:10.1016/j.cell.2004.12.020 · Cited by 1,688

Promoting Axon Regeneration in the Adult CNS by Modulation of the PTEN/mTOR Pathway

Park, K. K., Liu, K., Hu, Y., Smith, P. D., Wang, C., Cai, B., Xu, B., Connolly, L., Kramvis, I., Sahin, M., et al. (2008) · Science · doi:10.1126/science.1161566 · Cited by 1,686

Reactive Gliosis and the Multicellular Response to CNS Damage and Disease

Burda, J. E., & Sofroniew, M. V. (2014) · Neuron · doi:10.1016/j.neuron.2013.12.034 · Cited by 1,500

Semaphorin 6D regulate corralling, hematoma compaction and white matter injury in mice after intracerebral hemorrhage

Sun, T., Zeng, H., Fan, L., Jing, F., & Chen, G. (2022) · Journal of Stroke and Cerebrovascular Diseases · doi:10.1016/j.jstrokecerebrovasdis.2022.106803 · Cited by 2

Single-cell analysis combined with transcriptome sequencing identifies autophagy hub genes in macrophages after spinal cord injury

Ju, C., Liu, R., Ma, Y., Dong, H., Xu, R., Hu, H., & Hao, D. (2024) · Clinical Immunology · doi:10.1016/j.clim.2024.110412 · Cited by 2

Edonerpic maleate enhances functional recovery from spinal cord injury with cortical reorganization in non-human primates

Uramaru, K., Abe, H., Nakajima, W., Ota, W., Suzuki, M., Yokoyama, O., Yamamoto, T., Nishimura, Y., & Takahashi, T. (2025) · Brain Communications · doi:10.1093/braincomms/fcaf036 · Cited by 2

Lactate-mediated Ran lactylation at lysine 123 promotes astrocytes polarization after oxygen-glucose deprivation/reoxygenation

Wang, Z., Li, M., Guo, S., Deng, C., Wang, B., Gao, F., Lv, J., & Sun, L. (2025) · International Immunopharmacology · doi:10.1016/j.intimp.2025.115861 · Cited by 2

Enhanced Actin Dynamics: A Therapeutic Strategy for Axonal Regeneration?

Werner, H. B., & Nave, K. (2019) · Neuron · doi:10.1016/j.neuron.2019.09.008 · Cited by 2

Evaluation of the effect of myelotomy on nerve function in rats with spinal cord injury by diffusion tensor imaging

Liu, Y., Liu, C., Qin, C., Zhang, X., Feng, H., Wang, Z., & Li, J. (2020) · Acta Radiologica · doi:10.1177/0284185120975182 · Cited by 2

Sensorimotor and Locomotor Adjustments in the Chronic Post-Traumatic Spinal Cord Damage in Human Adults as Evidence of Activity-Dependent Neuroplasticity

Shapkova, E. Y., Емельянников, Д. В., & Larionova, Y. E. (2021) · Human Physiology · doi:10.1134/s0362119721040149 · Cited by 2

Historical Perspectives of Regenerative Rehabilitation: Recovering and Restoring Functional Capacity

Raymond‐Pope, C. J., Hoffman, D. B., Saunders, D., & Greising, S. M. (2022) · Physiology in health and disease · doi:10.1007/978-3-030-95884-8_1 · Cited by 2

Efficacy and safety of Buyang Huanwu Decoction in patients with spinal cord injury: A meta-analysis of randomized controlled trials

He, Z., Yang, S., Tan, Y., Liao, Y., & Song, S. (2024) · Medicine · doi:10.1097/md.0000000000037865 · Cited by 2

Spinal cord neural stem cells heterogeneity in postnatal development

Ban, J., & Mladinić, M. (2020) · STEMedicine · doi:10.37175/stemedicine.v1i1.19 · Cited by 2

GRP78-Mediated Signaling Contributes to Axonal Growth Resulting in Motor Function Recovery in Spinal Cord-Injured Mice

Tanie, Y., Kuboyama, T., & Tohda, C. (2020) · Frontiers in Pharmacology · doi:10.3389/fphar.2020.00789 · Cited by 2

Electrospun bioactive composites for neural tissue engineering applications

Bai, Y., He, L., Lou, X., & Quan, D. (2020) · Elsevier eBooks · doi:10.1016/b978-0-12-819611-3.00001-7 · Cited by 2

Prok2/PKR signaling regulates ferroptosis after spinal cord injury

Zhu, Q., Xu, T., Huang, Q., Gu, Q., Wang, J., Zhu, Y., Wang, L., Sha, W., Gao, R., Ge, J., et al. (2025) · Neuroscience · doi:10.1016/j.neuroscience.2025.02.030 · Cited by 1

The Outcomes of Schwann Cell Therapy on Functional Recovery, Axonal Regeneration, and Remyelination in Spinal Cord Injury: A Systematic Review Study

Asadollahi, K., Heidarizadi, S., & Azizi, M. (2025) · Current Stem Cell Research & Therapy · doi:10.2174/011574888x368052250722173956 · Cited by 1

The effects of UCN2 on neural cell function of spinal cord injury rats facilitate post-injury neuronal regeneration

Hu, Y., Liu, P., Tang, X.-L., Li, B., Yuan, L., Dou, F.-F., Zhao, L., & Zhang, B.-M. (2025) · Cellular Signalling · doi:10.1016/j.cellsig.2025.112134 · Cited by 1

AAV9-mediated KCC2 upregulation enhances functional recovery following cervical spinal cord injury

Zavvarian, M.-M., Modi, A. D., Khazaei, M., Luo, Z., Velumian, A. R., Hassan, O. I., Hong, J., Ahuja, C. S., Patel, Z. H., He, M., et al. (2025) · Communications Biology · doi:10.1038/s42003-025-08734-0 · Cited by 1

Modulation of the inflammatory microenvironment after SCI to achieve enhanced nerve regeneration using pteryxin-releasing methylacrylated hyaluronic acid

Hu, B., Sun, B., Zhao, Y., Chen, C., Wu, B., Zhang, H., Liu, B., Yang, X., & Fang, F. (2025) · Biomaterials Science · doi:10.1039/d5bm01322d · Cited by 1

Omaveloxolone promotes functional recovery of spinal cord injury by reducing inflammatory response and regulating macrophage polarization

Zhao, P., Yuan, W., Zhang, J., Gao, E., Zhang, D., Wu, Z., Zhang, Y., Chen, J., Hu, D., Fan, B., et al. (2026) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2025.1737798 · Cited by 1

Integrated cryopreservation-thawing-transplantation platform for neural stem cell-based spinal cord injury repair

Ren, J., Li, J., Wang, H., Feng, H., Hao, H., Chen, J., Li, Y., Xu, Z., Li, C., Jiang, W. J., et al. (2026) · Bioactive Materials · doi:10.1016/j.bioactmat.2026.01.024 · Cited by 1

Dual strategies for neural injury repair: Targeted modulation of reactive astrocytes and functional astrocyte transplantation

Cai, Z., Zhou, X., Teng, T., Li, H., Chen, T., Dai, S., & Zhang, K. (2026) · Neural Regeneration Research · doi:10.4103/nrr.nrr-d-25-01020 · Cited by 1

Reorganization of Spinal Cord Microarchitecture by Bioluminescent Optogenetic and Rehabilitative Interventions

Ageeva, T. V., Shigapova, R. R., Bilalova, A., Plotnikova, E., Akmanova, A., Rizvanov, A. A., & Mukhamedshina, Y. O. (2026) · Cells · doi:10.3390/cells15060571 · Cited by 1

Mesenchymal Stem Cell-Lysate Sustained-Release Nano-Hydrogel Alleviates Spinal Cord Injury by Inhibiting Ferroptosis and Mitochondrial Intrinsic Apoptosis

Sun, M. L., Wu, H., Liu, S., Jiang, C. L., Zhou, H., & Hou, A. (2026) · International Dental Journal · doi:10.1016/j.identj.2026.109557 · Cited by 1

Mechanisms and Applications of Conductive Biomaterials in Spinal Cord Injury Repair

Zhao, B., Wang, Z., Yu, T., Cui, X., Zhang, J., Danzeng, Q., Wang, W., Shen, Y., Ma, C., Zhao, Y., et al. (2026) · Biomaterials Research · doi:10.34133/bmr.0381 · Cited by 1

Screening the optimal rTSMS frequency to orchestrate immune-fibrotic remodeling for adult spinal cord repair

Hou, X., Zhou, S., Wang, Q., Sun, H., & Yu, H. (2026) · Frontiers in Neuroscience · doi:10.3389/fnins.2026.1845752 · Cited by 1

Neurorehabilitation Based on Spinal Cord Stimulation and Motor Training

Stolbkov, Y. K., & Gerasimenko, Y. P. (2023) · Успехи физиологических наук · doi:10.31857/s0301179823040070 · Cited by 1

Spinal Cord Injury Associated Disease of the Skeleton, an Unresolved Problem with Need for Multimodal Interventions

Cruz, E. C. E., McMillan, D. W., Reid, K. F., & Valderrábano, R. J. (2024) · Advanced Biology · doi:10.1002/adbi.202400213 · Cited by 1

Opportunities and Challenges of Biomaterials in Brain Disease

Zheng, W., Jiang, M., Dong, N., Fang, H., Tian, H., & Chen, X. (2025) · Advanced Healthcare Materials · doi:10.1002/adhm.202500746 · Cited by 2

General Aspects of Traumatic Neural Diseases and Requirements of Central Nervous System Implantable Biomaterials as Diagnostic and Therapeutic Tools

Dominguez, A. L., González‐Mayorga, A., López‐Dolado, E., & Serrano, M. C. (2021) · Springer eBooks · doi:10.1007/978-3-030-81400-7_1 · Cited by 1

Plastic Changes Induced by Motor Activity in Spinal Cord Injury

Stolbkov, Y. K., & Gerasimenko, Y. P. (2023) · Neuroscience and Behavioral Physiology · doi:10.1007/s11055-023-01438-0 · Cited by 1

Self-Catheterization Post-Cervical Spinal Cord Injury: Hand and Upper Extremity Rehabilitation

Gavaghan, G., & Maye, F. (2023) · Springer eBooks · doi:10.1007/978-981-99-1659-7_73 · Cited by 1

Spatiotemporal dynamics of molecular expression pattern and intercellular interactions in glial scar responding to spinal cord injuryPreprint

Gong, L., Gu, Y., Han, X., Luan, C., Wang, X., Sun, Y., Fang, M., Yang, S., Xu, L., Sun, H., et al. (2021) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2021.12.20.473346 · Cited by 1

Inducing Hebbian Plasticity at Multiple Spinal Cord Levels Restores Grasping and Walking in Humans With Tetraplegia: A Prospective StudyPreprint

Jo, H. J., Kizziar, E., Sangari, S., Chen, D., Kessler, A., Kim, K., Anschel, A. S., Heinemann, A. W., Mensh, B. D., Lieber, R. L., et al. (2021) · SSRN Electronic Journal · doi:10.2139/ssrn.3907191 · Cited by 1

Connexins are essential for the contribution of latent progenitors to healing after spinal cord injuryPreprint

Falco, M. V., Fabbiani, G., Prieto, D., Vidal, M., Benitez, M., Rehermann, M. I., Silvera, M. C., Simeone, R., Trigo, F. F., & Russo, R. E. (2026) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.64898/2026.01.16.699895 · Cited by 1

Nociceptive (Pain) Input After Spinal Cord Injury (SCI) Enhances Secondary Injury: Identifying Treatments that can be Translated to Clinical Practice

Grau, J. W. (2019)

Restoring neuron connections

Salinas, P. C. (2020) · Science · doi:10.1126/science.abd4762

Genetic control of neuronal activity enhances axonal growth only on permissive substratesPreprint

Mesquida-Veny, F., Martínez‐Torres, S., del Rı́o, J. A., & Hervera, A. (2022) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2022.01.21.477184

Spatiotemporal dynamics of molecular expression pattern and intercellular interactions in glial scar responding to spinal cord injuryPreprint

Zhou, S., Gong, L., Gu, Y., Han, X., Luan, C., Wang, X., Sun, Y., Fang, M., Yang, S., Xu, L., et al. (2022) · Research Square · doi:10.21203/rs.3.rs-1210885/v1

Three-dimensional nanofibrous sponges with controlled hierarchy regulating neural stem cell fate for spinal cord regenerationPreprint

Ni, S., Li, Z., Qi, Y., Sun, L., Li, Z., Chen, S., Zhang, Y., Ma, Y., Han, J., Zhang, Y., et al. (2022) · Research Square · doi:10.21203/rs.3.rs-1491678/v1

Femtosecond laser microdissection isolating regenerating C. elegans neurons for single cell RNA sequencingPreprint

Zhao, P., Martin, C., Ma, K.-Y., Jiang, N. J., & Ben‐Yakar, A. (2021) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2021.01.21.427576

Spinal cord injury

Boido, M., & Vercelli, A. (2022) · Elsevier eBooks · doi:10.1016/b978-0-323-85654-6.00050-2

Melatonin protect PC12 cells from hydrogen peroxide-induced damage via the Nrf2/HO-1 signaling pathwayPreprint

Zhang, Y., Guo, X., Cheng, X., Hu, X., Kang, J., Lin, A., Kang, X., & He, X. (2022) · Research Square · doi:10.21203/rs.3.rs-1668785/v1

Genetic or transcranial magnetic stimulation of B-RAF–MEK signaling promotes CST axon sprouting and functional regenerationPreprint

Boato, F., Guan, X., Zhu, Y., Ryu, Y., Voutounou, M., Rynne, C., Freschlin, C. R., Zumbo, P., Betel, D., Matho, K. S., et al. (2022) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2022.06.01.494346

Treating spinal cord injury with implanted spinal cord stimulators

You, H., Zheng, Y., & Alam, M. (2022) · Elsevier eBooks · doi:10.1016/b978-0-12-822498-4.00019-1

The assessment of biceps voluntary activation with transcranial magnetic stimulation in individuals with tetraplegia

Roumengous, T. P. T., & Peterson, C. L. (2022) · Restorative Neurology and Neuroscience · doi:10.3233/rnn-221254

Three-dimensional nanofibrous sponges with aligned architecture and controlled hierarchy regulating neural stem cell fate for spinal cord regenerationPreprint

Ni, S., Li, Z., Qi, Y., Sun, L., Li, Z., Chen, S., Zhang, Y., Ma, Y., Han, J., Wang, Z., et al. (2022) · Research Square · doi:10.21203/rs.3.rs-2004136/v1

Nanoneurology

Israel, L. L., & Holler, E. (2022) · Wiley eBooks · doi:10.1002/9781119558026.ch2

Spatiotemporal orchestration of multicellular transcriptional programs and communications in the early stage of spinal cord injuryPreprint

Wang, Z., Li, Z., Luan, T., Cui, G., Shu, S., Liang, Y., Xiao, J., Zhang, K., Yu, W., Cui, J., et al. (2022) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2022.10.07.511269

Humans at the dawn of the in-body electrical nerve stimulation era

Possover, M. (2022) · Facts Views and Vision in ObGyn · doi:10.52054/fvvo.14.4.041

Study of Combinatorial Cell Therapy and Neuroprotective Agents for the Treatment of Spinal Cord Injury in Experimental Models

Villamil, P. B. (2022) · doi:10.4995/thesis/10251/191500

Advancing spinal cord injury research with optical clearing, light sheet microscopy, and artificial intelligence-based image analysis

Li, Q., Sandoval, A., & Chen, B. (2023) · Neural Regeneration Research · doi:10.4103/1673-5374.373708

Self-Catheterization Post-Cervical Spinal Cord Injury: Hand and Upper Extremity Rehabilitation

Gavaghan, G., & Maye, F. (2022) · Springer eBooks · doi:10.1007/978-981-16-7939-1_73-1

A digital bridge between brain and spinal cord restores walking after paralysis

Courtine, G., & Bloch, J. (2023) · Nature · doi:10.1038/d41586-023-01345-x

Vasculature cells control neuroglial co-localization and synaptic connection in a central nervous system tissue mimic system

Moon, S., & Ito, Y. (2023) · Human Cell · doi:10.1007/s13577-023-00955-x

A spinal cord injury time and severity consensus transcriptomic reference suite in rat reveals translationally-relevant biomarker genesPreprint

Grillo-Risco, R., Hidalgo, M. R., Martínez-Rojas, B., Moreno‐Manzano, V., & Garcia‐García, F. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.01.30.578030

Investigation of Transcriptome Profile of Genes in Rats with Injured Spinal Cord after Transplantation of Menstrual Blood-derived Stem Cells and Treadmill Training by Sequencing AnalysisPreprint

Sun, Y., Zhang, J., Hong, H., & Chen, L. (2024) · Research Square · doi:10.21203/rs.3.rs-4177689/v1

Additional file 1 of Imatinib inhibits pericyte-fibroblast transition and inflammation and promotes axon regeneration by blocking the PDGF-BB/PDGFRβ pathway in spinal cord injury

Yao, F., Luo, Y., Liu, Y.-C., Chen, Y., Li, Y.-T., Hu, X., You, X., Yu, S., Li, Z., Chen, L., et al. (2022) · Figshare · doi:10.6084/m9.figshare.21213362

Meta-SCI app: a comprehensive transcriptional reference for understanding the severity and progression of spinal cord injuryPreprint

Grillo-Risco, R., Hidalgo, M. R., Martínez-Rojas, B., Moreno‐Manzano, V., & García-García, F. (2024) · Research Square · doi:10.21203/rs.3.rs-4358401/v1

A TrkB-mTOR Peptidomimetic Promotes Axon Regeneration and Restores Walking After Adult Spinal Cord InjuryPreprint

Bai, C., She, C., Shan, H., Chai, J.-L., Xu, C., Marshall, J. J., Cao, C., & Zhou, X. (2024) · SSRN Electronic Journal · doi:10.2139/ssrn.5055101

A reactive oxygen species- and acidic pH-responsive hydrogel loaded with Tempol and poly-lysine enhances spinal cord injury repair in rat modelsPreprint

Xia, G., Shuai, R., Li, Z., Tang, C., Zhang, Y., Kong, Q., Li, W., Ma, F., Li, X., & Du, Y. (2025) · Research Square · doi:10.21203/rs.3.rs-6993042/v1

In Vivo Local Administration of Para-Amino-Bebblistatin to the Injured Spinal Cord Fails to Improve the NaChBac-Expressing DRGs Transplantation

Hingorani, S., Paniagua, G., Sánchez-Huertas, C., & Moreno‐Manzano, V. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms262110479

Axon regeneration in the central nervous system

Zochodne, D. W. (2025) · Elsevier eBooks · doi:10.1016/b978-0-443-22065-4.00002-6

References

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Advances in Bionic Therapies for Targeting Neural Circuit Reconstruction and Integration for Spinal Cord Injury

Li, T., Zhao, Z.-H., Tang, H., Chen, Z., Lu, Z., Yang, X.-L., Zhao, L.-L., Li, Y., Dang, M., Chen, Z., et al. (2025) · Cellular and Molecular Neurobiology · doi:10.1007/s10571-025-01647-w

Hederagenin may promote functional recovery following spinal cord injury by modulating microglial polarization through the PPAR-γ signaling pathway

Wu, L., Lu, D., Yao, J.-Z., Zuo, W., & Xu, J. (2025) · Journal of Spinal Cord Medicine · doi:10.1080/10790268.2025.2593706

Additional file 4 of Photobiomodulation promotes spinal cord injury repair by inhibiting macrophage polarization through lncRNA TUG1-miR-1192/TLR3 axis

Ju, C., Ma, Y., Zuo, X., Wang, X., Song, Z., Zhang, Z., Zhu, Z., Li, X., Liang, Z., Ding, T., et al. (2024) · Figshare · doi:10.6084/m9.figshare.26562856

Additional file 1 of Photobiomodulation promotes spinal cord injury repair by inhibiting macrophage polarization through lncRNA TUG1-miR-1192/TLR3 axis

Ju, C., Ma, Y., Zuo, X., Wang, X., Song, Z., Zhang, Z., Zhu, Z., Li, X., Liang, Z., Ding, T., et al. (2024) · Figshare · doi:10.6084/m9.figshare.26562844

Additional file 3 of Photobiomodulation promotes spinal cord injury repair by inhibiting macrophage polarization through lncRNA TUG1-miR-1192/TLR3 axis

Ju, C., Ma, Y., Zuo, X., Wang, X., Song, Z., Zhang, Z., Zhu, Z., Li, X., Liang, Z., Ding, T., et al. (2024) · Figshare · doi:10.6084/m9.figshare.26562850

Additional file 6 of Photobiomodulation promotes spinal cord injury repair by inhibiting macrophage polarization through lncRNA TUG1-miR-1192/TLR3 axis

Ju, C., Ma, Y., Zuo, X., Wang, X., Song, Z., Zhang, Z., Zhu, Z., Li, X., Liang, Z., Ding, T., et al. (2024) · Figshare · doi:10.6084/m9.figshare.26562865

Additional file 1 of Clinical translation of stem cell therapy for spinal cord injury still premature: results from a single-arm meta-analysis based on 62 clinical trials

Shang, Z., Wang, M., Zhang, B., Wang, X., & Wanyan, P. (2022) · Figshare · doi:10.6084/m9.figshare.20921215

Additional file 2 of Photobiomodulation promotes spinal cord injury repair by inhibiting macrophage polarization through lncRNA TUG1-miR-1192/TLR3 axis

Ju, C., Ma, Y., Zuo, X., Wang, X., Song, Z., Zhang, Z., Zhu, Z., Li, X., Liang, Z., Ding, T., et al. (2024) · Figshare · doi:10.6084/m9.figshare.26562847

Additional file 5 of Photobiomodulation promotes spinal cord injury repair by inhibiting macrophage polarization through lncRNA TUG1-miR-1192/TLR3 axis

Ju, C., Ma, Y., Zuo, X., Wang, X., Song, Z., Zhang, Z., Zhu, Z., Li, X., Liang, Z., Ding, T., et al. (2024) · Figshare · doi:10.6084/m9.figshare.26562862

Thoracic Fracture-Dislocation with Complete Vertebral Body Translation and Spinal Cord Transection

Negishi, R., Takasawa, E., Sorimachi, Y., & Chikuda, H. (2026) · JBJS Case Connector · doi:10.2106/jbjs.cc.24.00482

MAFG Induces the Methylation of CRYAB to Promote the Activation of A1 Astrocyte After Spinal Cord Injury

Li, X., Zhu, Z., Wang, Y. L., Wan, H., Wang, Z., & Qiao, W. (2026) · Immunity Inflammation and Disease · doi:10.1002/iid3.70334

NR4A1 attenuates neuroinflammation after spinal cord injury by modulating microglial polarization via negatively regulating the VAV1 pathway

Qu, N., You, W., Gong, L., Wang, K. Y., Shu, Q. W., Tao, L., Zhong, Y., Qi, Q., & Zuo, W. (2026) · Cellular Signalling · doi:10.1016/j.cellsig.2026.112385

TTBK2‐Driven Ciliogenesis Is Required for Intrinsic Neuronal Regeneration After Spinal Cord Injury

Zhang, R., Su, P., Tian, Z., Du, H., Wang, J., Yang, X., & Qi, Z. (2026) · CNS Neuroscience & Therapeutics · doi:10.1002/cns.70763

Can Transcutaneous Vagus Nerve Stimulation be Effective After Rats’ Spinal Cord Injury?

Tanaka, T., Gökden, M., & Landes, R. D. (2026) · Cureus · doi:10.7759/cureus.102944

Neuroprotection and immunomodulation after treatment with NeuroBoost and NeuroHeal following ventral root crush in mice

Coser, L. D. O., Balzani, M. F. V., Lombardi, J., Cartarozzi, L. P., & de Oliveira, A. L. R. (2026) · IBRO Neuroscience Reports · doi:10.1016/j.ibneur.2026.02.011

3D-Printed, Cellulose-Derived Scaffold Promotes Neuroregeneration and Functional Recovery after Spinal Cord Injury

Shi, X., Zhang, Y., Zhou, C., Xu, F., & Wang, C. (2026) · ACS Biomaterials Science & Engineering · doi:10.1021/acsbiomaterials.5c02180

Sirtuin1 modulates P53/Nrf2 pathway to promote spinal cord injury repair

Huang, X., Shi, S., Zhang, Z., Zhao, Z., Gao, J., Zhang, M., Qin, L., & Yu, X. (2026) · Neurological Sciences · doi:10.1007/s10072-025-08604-x

An integrated analysis of spinal cord transcriptome and gut microbiome unravel age-associated host-microbiome interactions following spinal cord injury

Jing, Y., Bai, F., Li, Z., Wang, Q., Li, Y., Liu, W., Zhang, S., Gao, C., & Yu, Y. (2026) · Frontiers in Immunology · doi:10.3389/fimmu.2026.1602745

A reparative neutrophil subpopulation promotes spinal cord regeneration in zebrafish by controlling macrophage inflammation via Il-4Preprint

Tian, X., Docampo-Seara, A., Heilemann, K., Kessel, F., Zöller, D., Bretschneider, A., Becker, T., & Becker, C. G. (2026) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.64898/2026.02.25.707887

Autologous Neural Stem Cell Encapsulation in CT04-Integrated Fibrin Hydrogel Enhances Tissue Regeneration After Spinal Cord Injury in Monkeys

Jaberi, R., Okoro, P. D., Hajinasrollah, M., Kheirabadi, M. Z., Mirsadeghi, S., Rahmani, S., Nazemi, Z., Noshadi, I., Kobeissy, F. H., & Kiani, S. (2026) · Molecular Neurobiology · doi:10.1007/s12035-026-05787-y

Microglial lipid metabolism and epigenetic regulation: Emerging targets for spinal cord injury therapy

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Molecular mechanisms orchestrating commissural axon guidance

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Effets des activateurs pharmacologiques de Nrf2 sur la réponse antioxydante et anti-inflammatoire dans le macrophage humain

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Diversity of visual projections in vertebrates

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Adaptation du mouvement humain à de nouvelles dynamiques gravito-inertielles induites par l’interaction avec un exosquelette de membre supérieur actionné

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Current Preclinical and Clinical Evidence of Shock Wave Therapy for Spinal Cord Injury: A Systematic Review

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Spatiotemporal Drug Delivery via a Neonatal Spinal Cord ECM Hydrogel for Biomimetic Microenvironment Remodeling After Spinal Cord Injury

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Recovery in gait and posture: a network-based approach to the assessment of rehabilitation effectiveness after spinal cord injury

Ageeva, T. V., Grigarevichius, K. R., Sinitca, A., Sabirov, D., Tsygankova, M., Сергеевич, П. Н., Bogachev, M. I., Rizvanov, A. A., & Mukhamedshina, Y. O. (2026) · Frontiers in Network Physiology · doi:10.3389/fnetp.2026.1853254

An integrated hydrogel-V3 interneuron therapy promotes functional repair of spinal cord injury via neural circuit reconstruction and microenvironment remodeling

Yin, W., Ma, G., Xu, J., Chen, X., Liu, Y., Zhou, Q., Tang, G., Shi, Z., Yang, G., & Chen, H. (2026) · Bioactive Materials · doi:10.1016/j.bioactmat.2026.05.034

Biofunctional biomaterials for traumatic spinal cord injury repair: From microenvironmental reprogramming to functional reconstruction

Yu, J., Gan, K., Lai, H., Li, J. X., Chao, M., Shu, G., Chen, M., Ji, J., & Shen, L. (2026) · Precision medicine and engineering. · doi:10.1016/j.preme.2026.100078

Sustainable cellulose nanofibrils as ultrasound-driven piezoelectric interfaces for wireless neuromodulation

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Surface circumferential spinal cord recording in freely moving rodents

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Transspinal stimulation preceding step training reorganizes spinal locomotor circuits in human spinal cord injury: a randomized sham-controlled clinical trial

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SVF Combined with HGF-Functionalized Self-Assembling Peptide Hydrogel Promotes Spinal Cord Injury Repair in Rats

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Electroactive scaffolds for spinal cord injury repair: Modulating the electrophysiological homeostasis

Su, X., Wang, S., Tian, J., Zhang, Z., Zhao, S., Lei, B., & Zhang, Y. (2026) · Translational research · doi:10.1016/j.trsl.2026.07.009

Engineering functional vasculatures to reconstruct sympathetic-parasympathetic circuits for bladder function after spinal cord injury

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Editorial: Bioengineering for spinal cord injury

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Hierarchical targeting biomimetic nanoparticles directing to lesion site and mitochondria promote neuroregeneration and attenuate inflammation after spinal cord injury

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Regenerative and Repair Strategies for the Central Nervous System: Progress in Basic and Clinical Research on Spinal Cord Injury

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