Hexadirectional coding of visual space in human entorhinal cortex
Open accessAbstract
Entorhinal grid cells map the local environment, but their involvement beyond spatial navigation remains elusive. We examined human functional MRI responses during a highly controlled visual tracking task and show that entorhinal cortex exhibited a sixfold rotationally symmetric signal encoding gaze direction. Our results provide evidence for a grid-like entorhinal code for visual space and suggest a more general role of the entorhinal grid system in coding information along continuous dimensions.
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Grid cells in the ERC are posited to provide a structural scaffold for episodic events and spatial representations, with ERC acting as a mediator between HPC and neocortex by providing a geometric code for the global properties of the environment.
“Grid cells in the ERC are posited to provide a structural scaffold for episodic events and spatial representations 7 , with ERC acting as a mediator between HPC and neocortex by providing a geometric code for the global properties of the environment 155,156 .”
From From cognitive maps to spatial schemas (2023) · cites this paper as [156]
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- Authors
- Nau, M., Navarro Schröder, T., Bellmund, J. L. S., & Doeller, C. F.
- Affiliations
- Radboud University Nijmegen (NL)
- Corresponding author
- Nau, Matthias
- Doeller, Christian F.
- Venue
- Nature Neuroscience
- Published
- 2018-01-08
- Volume
- 21
- Issue
- 2
- Pages
- 188-190
- ISSN
- 1097-6256 (ISSN-L)
- 1546-1726
- OpenAlex
- W2782119748
- Cited by
- 182
- References
- 20
- Citations by year
- 2026: 11 · 2025: 14 · 2024: 24 · 2023: 24 · 2022: 21 · 2021: 26 · 2020: 22 · 2019: 21 · 2018: 18 · 2017: 1
- FWCI
- 12.84
- Type
- journal article
- Language
- en
- Open access
- green
- hdl.handle.net
- Licence
- Locations
- Nature Neuroscience (publishedVersion)
- PubMed (publishedVersion)
- Max Planck Digital Library (submittedVersion)
- NORA - Norwegian Open Research Archives (submittedVersion, other-oa)
- MPG.PuRe (Max Planck Society) (submittedVersion)
- Radboud Repository (Radboud University) (submittedVersion)
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Memory and Neural Mechanisms
- Physical Sciences › Engineering › Automotive Engineering › Spatial Cognition and Navigation
- Life Sciences › Neuroscience › Cognitive Neuroscience › Visual perception and processing mechanisms
- Keywords
- entorhinal cortex, grid cells, gaze direction, eye movements, rotational symmetry, spatial cognition
- MeSH terms
- Grid Cells, Adolescent, Adult, Attention, Eye Movements, Female, Humans, Image Processing, Computer-Assisted, Magnetic Resonance Imaging, Male, Orientation, Oxygen, Space Perception, Visual Pathways, Linear Models, Entorhinal Cortex, Young Adult, Spatial Navigation
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