Single-cell analysis of olfactory neurogenesis and differentiation in adult humans

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(2008) · Journal of Machine Learning Research · Cited by 33,051 · see citing works

Fast unfolding of communities in large networks

Blondel, V. D., Guillaume, J.-L., Lambiotte, R., & Lefebvre, E. (2008) · Journal of Statistical Mechanics: Theory and Experiment · doi:10.1088/1742-5468/2008/10/p10008 · Cited by 21,424 · see citing works

Comprehensive Integration of Single-Cell Data

Stuart, T., Butler, A., Hoffman, P., Hafemeister, C., Papalexi, E., Mauck, W. M., Hao, Y., Stoeckius, M., Smibert, P., & Satija, R. (2019) · Cell · doi:10.1016/j.cell.2019.05.031 · Cited by 15,453 · see citing works

Integrating single-cell transcriptomic data across different conditions, technologies, and species

Butler, A., Hoffman, P., Smibert, P., Papalexi, E., & Satija, R. (2018) · Nature Biotechnology · doi:10.1038/nbt.4096 · Cited by 13,174 · see citing works

Enrichr: a comprehensive gene set enrichment analysis web server 2016 update

Kuleshov, M. V., Jones, M. R., Rouillard, A. D., Fernandez, N. F., Duan, Q., Wang, Z., Koplev, S., Jenkins, S. L., Jagodnik, K. M., Lachmann, A., et al. (2016) · Nucleic Acids Research · doi:10.1093/nar/gkw377 · Cited by 10,799 · see citing works

Complex heatmaps reveal patterns and correlations in multidimensional genomic data

Gu, Z., Eils, R., & Schlesner, M. (2016) · Bioinformatics · doi:10.1093/bioinformatics/btw313 · Cited by 10,122 · see citing works

UMAP: Uniform Manifold Approximation and Projection

McInnes, L., Healy, J., Saul, N., & Großberger, L. (2018) · Journal of Open Source Software · doi:10.21105/joss.00861 · Cited by 9,826 · see citing works

Dimensionality reduction for visualizing single-cell data using UMAP

Becht, E., McInnes, L., Healy, J., Dutertre, C.-A., Kwok, I. W. H., Ng, L. G., Ginhoux, F., & Newell, E. W. (2019) · Nature Biotechnology · doi:10.1038/nbt.4314 · Cited by 5,358 · see citing works

A novel multigene family may encode odorant receptors: A molecular basis for odor recognition

Buck, L., & Axel, R. (1991) · Cell · doi:10.1016/0092-8674(91)90418-x · Cited by 4,987 · see citing works

Fast gene set enrichment analysisPreprint

Korotkevich, G., Sukhov, V., Budin, N., Shpak, B., Artyomov, M. N., & Sergushichev, A. (2016) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/060012 · Cited by 3,742 · see citing works

The Reactome Pathway Knowledgebase

Fabregat, A., Jupe, S., Matthews, L. R., Sidiropoulos, K., Gillespie, M. E., Garapati, P. V., Haw, R., Jassal, B., Korninger, F., May, B., et al. (2017) · Nucleic Acids Research · doi:10.1093/nar/gkx1132 · Cited by 2,798 · see citing works

The Reactome pathway Knowledgebase

Fabregat, A., Sidiropoulos, K., Garapati, P., Gillespie, M., Hausmann, K., Haw, R., Jassal, B., Jupe, S., Korninger, F., McKay, S., et al. (2016) · Nucleic Acids Research · doi:10.1093/nar/gkv1351 · Cited by 1,201 · see citing works

Allelic inactivation regulates olfactory receptor gene expression

Chess, A. J., Simon, I., Cedar, H., & Axel, R. (1994) · Cell · doi:10.1016/s0092-8674(94)90562-2 · Cited by 1,066 · see citing works

Contribution of olfactory neural stem cells to tissue maintenance and regeneration

Leung, C. T., Coulombe, P. A., & Reed, R. R. (2007) · Nature Neuroscience · doi:10.1038/nn1882 · Cited by 466 · see citing works

Sox17 is indispensable for acquisition and maintenance of arterial identity

Corada, M., Orsenigo, F., Morini, M. F., Pitulescu, M. E., Bhat, G. P., Nyqvist, D., Breviario, F., Conti, V., Briot, A., Iruela‐Arispe, M. L., et al. (2013) · Nature Communications · doi:10.1038/ncomms3609 · Cited by 301 · see citing works

Olfactory sensory neurons are trophically dependent on the olfactory bulb for their prolonged survival

Schwob, J., Szumowski, K., & Stasky, A. (1992) · Journal of Neuroscience · doi:10.1523/jneurosci.12-10-03896.1992 · Cited by 300 · see citing works

An autoradiographic study of the mouse olfactory epithelium: Evidence for long‐lived receptors

Hinds, J. W., Hinds, P. L., & McNelly, N. A. F. (1984) · The Anatomical Record · doi:10.1002/ar.1092100213 · Cited by 272 · see citing works

Reconstitution of the rat olfactory epithelium after methyl bromide‐induced lesion

Schwob, J. E., Youngentob, S. L., & Mezza, R. C. (1995) · The Journal of Comparative Neurology · doi:10.1002/cne.903590103 · Cited by 267 · see citing works

Lhx2/Ldb1-mediated trans interactions regulate olfactory receptor choice

Monahan, K., Horta, A., & Lomvardas, S. (2019) · Nature · doi:10.1038/s41586-018-0845-0 · Cited by 245 · see citing works

A lifetime of neurogenesis in the olfactory system

Brann, J. H., & Firestein, S. (2014) · Frontiers in Neuroscience · doi:10.3389/fnins.2014.00182 · Cited by 238 · see citing works

Deconstructing Olfactory Stem Cell Trajectories at Single-Cell Resolution

Fletcher, R. B., Das, D., Gadye, L., Street, K., Baudhuin, A., Wagner, A., Cole, M. B., Flores-Ramirez, Q., Choi, Y. G., Yosef, N., et al. (2017) · Cell stem cell · doi:10.1016/j.stem.2017.04.003 · Cited by 229 · see citing works

An Epigenetic Trap Stabilizes Singular Olfactory Receptor Expression

Lyons, D. B., Allen, W. E., Goh, T., Tsai, L., Barnea, G., & Lomvardas, S. (2013) · Cell · doi:10.1016/j.cell.2013.06.039 · Cited by 189 · see citing works

Immunohistochemical characterization of human olfactory tissue

Holbrook, E. H., Wu, E., Curry, W. T., Lin, D. T., & Schwob, J. E. (2011) · The Laryngoscope · doi:10.1002/lary.21856 · Cited by 189 · see citing works

The LIM-homeodomain protein Lhx2 is required for complete development of mouse olfactory sensory neurons

Hirota, J., & Mombaerts, P. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0400940101 · Cited by 152 · see citing works

In vivo and in vitro neurogenesis in human olfactory epithelium

Hahn, C.-G., Han, L., Rawson, N. E., Mirza, N. A., Borgmann‐Winter, K. E., Lenox, R. H., & Arnold, S. E. (2005) · The Journal of Comparative Neurology · doi:10.1002/cne.20424 · Cited by 129 · see citing works

Acute inflammation regulates neuroregeneration through the NF-κB pathway in olfactory epithelium

Chen, M., Reed, R. R., & Lane, A. P. (2017) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1620664114 · Cited by 116 · see citing works

Neurogenesis of sensory neurons in the primate olfactory system after section of the fila olfactoria

Graziadei, P. P. C., Karlan, M. S., Monti, G., & Bernstein, J. J. (1980) · Brain Research · doi:10.1016/0006-8993(80)90976-2 · Cited by 115 · see citing works

Adult c‐Kit(+) progenitor cells are necessary for maintenance and regeneration of olfactory neurons

Goldstein, B. J., Goss, G. M., Hatzistergos, K. E., Rangel, É. B., Seidler, B., Saur, D., & Hare, J. M. (2014) · The Journal of Comparative Neurology · doi:10.1002/cne.23653 · Cited by 51 · see citing works

Contribution of Polycomb group proteins to olfactory basal stem cell self-renewal in a novel c-KIT+ culture model and in vivo

Goldstein, B. J., Goss, G. M., Choi, R., Saur, D., Seidler, B., Hare, J. M., & Chaudhari, N. (2016) · Development · doi:10.1242/dev.142653 · Cited by 34 · see citing works

The smelling of Hedione results in sex-differentiated human brain activity

Wallrabenstein, I., Gerber, J., Rasche, S., Croy, I., Kurtenbach, S., Hummel, T., & Hatt, H. (2015) · NeuroImage · doi:10.1016/j.neuroimage.2015.03.029 · Cited by 31 · see citing works

Neuropilin-1 facilitates SARS-CoV-2 cell entry and infectivity

Cantuti-Castelvetri, L., Ojha, R., Pedro, L. D., Djannatian, M., Franz, J., Kuivanen, S., van der Meer, F., Kallio, K., Kaya, T., Anastasina, M., et al. (2020) · Science · doi:10.1126/science.abd2985 · Cited by 1,925 · see citing works

SARS-CoV-2 Reverse Genetics Reveals a Variable Infection Gradient in the Respiratory Tract

Hou, Y. J., Okuda, K., Edwards, C. E., Martinez, D. R., Asakura, T., Dinnon, K. H., Kato, T., Lee, R. E., Yount, B. L., Mascenik, T. M., et al. (2020) · Cell · doi:10.1016/j.cell.2020.05.042 · Cited by 1,488 · see citing works

Non-neuronal expression of SARS-CoV-2 entry genes in the olfactory system suggests mechanisms underlying COVID-19-associated anosmia

Brann, D. H., Tsukahara, T., Weinreb, C., Lipovsek, M., Van den Berge, K., Gong, B., Chance, R., Macaulay, I. C., Chou, H.-J., Fletcher, R. B., et al. (2020) · Science Advances · doi:10.1126/sciadv.abc5801 · Cited by 1,198 · see citing works

Ageing and rejuvenation of tissue stem cells and their niches

Brunet, A., Goodell, M. A., & Rando, T. A. (2023) · Nature Reviews Molecular Cell Biology · doi:10.1038/s41580-022-00510-w · Cited by 407 · see citing works

Anosmia in COVID-19: Underlying Mechanisms and Assessment of an Olfactory Route to Brain Infection

Butowt, R., & von Bartheld, C. S. (2021) · The Neuroscientist · doi:10.1177/1073858420956905 · Cited by 345 · see citing works

Single-cell and spatial transcriptomics: deciphering brain complexity in health and disease

Piwecka, M., Rajewsky, N., & Rybak-Wolf, A. (2023) · Nature Reviews Neurology · doi:10.1038/s41582-023-00809-y · Cited by 320 · see citing works

SARS-CoV-2 receptor and entry genes are expressed by sustentacular cells in the human olfactory neuroepithelium

Fodoulian, L., Tuberosa, J., Rossier, D., Boillat, M., Kan, C., Pauli, V., Egervari, K., Lobrinus, J. A., Landis, B. N., Carleton, A., et al. (2020) · doi:10.1101/2020.03.31.013268 · Cited by 286 · see citing works

Aging and Rejuvenation of Neural Stem Cells and Their Niches

Navarro Negredo, P., Yeo, R. W., & Brunet, A. (2020) · Cell Stem Cell · doi:10.1016/j.stem.2020.07.002 · Cited by 246 · see citing works

Motor and non-motor circuit disturbances in early Parkinson disease: which happens first?

Blesa, J., Foffani, G., Dehay, B., Bezard, E., & Obeso, J. A. (2022) · Nature Reviews Neuroscience · doi:10.1038/s41583-021-00542-9 · Cited by 232 · see citing works

A pan-tissue DNA methylation atlas enables in silico decomposition of human tissue methylomes at cell-type resolution

Zhu, T., Liu, J., Beck, S., Pan, S., Capper, D., Lechner, M., Thirlwell, C., Breeze, C. E., & Teschendorff, A. E. (2022) · Nature Methods · doi:10.1038/s41592-022-01412-7 · Cited by 103 · see citing works

Neurogenesis persists in the subependymal layer of the adult mouse brain

Corotto, F. S., Henegar, J. A., & MARUNIAK, J. A. (1993) · Neuroscience Letters · doi:10.1016/0304-3940(93)90748-a · Cited by 267 · see citing works

Human olfaction is not neurogenesis-dependent

Lewis, S. (2012) · Nature reviews. Neuroscience · doi:10.1038/nrn3286

Peripheral contributions to olfactory bulb cell populations (migrations towards the olfactory bulb)

Blanchart, A., Martín-López, E., Carlos, J., et al. (2010) · Glia · doi:10.1002/glia.21100 · Cited by 28 · see citing works

Use of olfactory ensheathing cells as candidates for transplant-mediated repair of central nervous system lesions

Barnett, S. C. (2003) · Springer eBooks · doi:10.1007/978-3-7091-6016-9_3

Ultrastructural analysis of olfactory ensheathing cells derived from olfactory bulb and nerve of neonatal and juvenile rats

Gómez, R. M., Ghotme, K. A., Botero, L., et al. (2015) · Neuroscience Research · doi:10.1016/j.neures.2015.07.012 · Cited by 7 · see citing works